Nfab014801.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nomada fabriciana
Gene Symbol
PRDM2
Assembly
GCA_907165295.1
Location
OU015689.1:19172046-19176596[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.0054 0.52 11.0 2.5 3 23 76 96 75 96 0.97
2 19 1.2e-05 0.0011 19.4 2.0 1 23 102 124 102 124 0.99
3 19 7.7e-05 0.0075 16.8 1.0 1 23 129 152 129 152 0.98
4 19 0.0028 0.27 11.9 2.9 1 20 158 177 158 180 0.94
5 19 1.5e-05 0.0014 19.1 3.2 1 23 185 208 185 208 0.95
6 19 1.9e-06 0.00018 21.9 0.7 1 23 216 238 216 238 0.98
7 19 1.4e-06 0.00014 22.2 3.3 1 23 242 264 242 264 0.98
8 19 0.0001 0.0096 16.5 0.2 1 23 270 292 270 292 0.98
9 19 0.00023 0.023 15.3 0.9 1 23 298 320 298 320 0.96
10 19 0.0012 0.11 13.1 0.5 2 23 555 577 554 577 0.95
11 19 0.00091 0.088 13.4 1.2 1 23 581 603 581 603 0.98
12 19 0.00037 0.035 14.7 1.6 1 23 609 632 609 632 0.97
13 19 1.4e-05 0.0014 19.1 0.8 1 23 639 662 639 662 0.97
14 19 0.00043 0.041 14.5 2.8 1 23 697 720 697 720 0.96
15 19 1.1 1e+02 3.8 0.2 5 20 733 748 732 750 0.91
16 19 0.00077 0.074 13.7 0.8 1 23 757 779 757 779 0.95
17 19 1.4e-07 1.4e-05 25.4 1.7 1 23 783 805 783 805 0.96
18 19 1.7e-05 0.0017 18.9 1.1 1 23 811 833 811 833 0.98
19 19 8.8e-07 8.4e-05 22.9 1.1 1 23 839 861 839 861 0.99

Sequence Information

Coding Sequence
ATGCACGACCTTTGGATCAGAGCTCCGGGGATCGTAGAAGGGTACGCGAATTCCAAAGGCAACGGTGGTAAGGACGTTGATATCAAAGCCAGACCCTCAAGAGCTTTGTCTGCTTCGTCGTTAGCGGGGCAAACCAGATGGATCCCAATCGCTGTCCGCGAATCGCATAAAACTGACGCTCTGATAAATACGACAGTCAAAGACGATAACGAACGAAAACGATTCTGCGTCATCTGCTCGGTGTATTTCTGCAGACAGAGAGACTACAAACGTCACATGGTGATGCACAGTGATCTAACGCCATATAAATGCGAGACTTGCCACCTCACCTTCAAACGTTTGTCCGGGCTGGCCGTTCACAAGCGCGTCCATCGTGGGATAGTGTTCACGTGCGACATCTGTGGATTCGCCACGATCAAAAAGTCCACGCTGACCATGCATCGTCGAAAGTTGCACGAGCGTGACTATTCGTTCCCCTGCAACCAGTGCGACAAATTTTTCATGTCGAACGCCGACCTGCAGGACCACAAGAGCTGTCACCTGGGTGAAACGTTCGCCTGCGATATCTGCGAGAAGGTCTACTCGCAGAAGAGTTATTTGAAAAGGCACAAACACAAGATGCACGATGCACACGAACCTCCTAAGTTTAAGTGCGACGTGTGCAAGAAGAGTTTCGTCAGCGGGAGCAATCTTCGTAATCACGCCAAAGTGCATTTGCAGGTACACCAGTGCTCCTACTGCGGCAAACAGTTCGCGAACAATCGAAACTTAACCGCGCACAATAGGAAGCACACAGGGGAGAAACCGTACAAGTGTAAAGTTTGCACAGAAAGTTTCGCCGCTTTATCGACACTCACTGTGCACGAACTCACGCACACCGAGGAGAAGCCGTATCTCTGCGATCTGTGTGGCAAGTGGTTCACGCAGAGGAGTAGTATGATGGTGCACCGTAAGACGCATCCTGGAAGTGACACTATACCGCCGCCTGAGAGGTCGTCGATTGCAGAAACGACTCGGGGCCAAGATAGAATTGATCGAGTGCCATACCAAGTTGCTATTCCAGTGTCTAGCCTGGCCGCGCACAATTCGATGCTGTGGAAAATCGAAGTAGACTGTGACGACGGCGACAGTGAAAGAACAAAGGCGATCGTAGAAACCGAATTTGACCGCGGCGTCCCCCCGGGGAAACGAATAAACGACGAGACGGTGGTAGAATCGACGAAAACAGTTTTGGTGCCTGTTCGGGATCCAGTGACGCGGCAGGTGAAAAATATATTGGTACCCGTTGAAGTGAAAGACGAGTCTGGCTTGAACATAATCAAGAGTGTGTTGATACCGGTCCAGGGTGGCGATGGATTGGTGTCTTACGAGATCAAAAGGGTTGTGGTACCGATCCAGCCGGTACTGAGCATACCTCAAAGGAAACAGACCGATACCAGGCCGGGTATGAATAAAAACAAATGGAAGCAAGCTAGTAACAAGAATACCAAAGAAACTGAGGAAAAGATGAAATTGGAGGCGGAGGAAAGGGAGAAGGAGCAGATAAAGAAGTCGGGAGAAGAAGAGGAGAGAACGACAGAAGGAACACAGAAAAGTGTACCAGCAGAAGGTGTCCCGAATGGGGATGTGGATCAAGTCCACATTCTGGACACCCTACGCACAACTTGTCCGTTCTGTGAGAAACGTTACAGGGACGTGGACGAAATGCAGAAGCACGTATCGAAAGTGCACAAGAAGCCCTACAATTGCGACAAGTGCCGCAAGGGTTACTTCACCGATTACGCGCTCGAGGAGCATCAGAAAACGCACGAGTTGCCTTCTTTCTATCAGTGTTCCATCTGTCAGCTGCAGTACAAAACCACGAGCGGCCTGAAGAACCATCGCACCCGAGAGCACACTAATCTGAAACCGAACTTCACGTGCGACTACTGTGGGAAACGGTTCAAACTGAAACTGGACCTGGCCCTCCACATCAATCGATCGCACATGAACGCCACGCATATATGCAGATTCTGCGGTATGGCGGTGAAGAATATCGCGCATCACGAATTGAAGCACGGACACGCTAGAAAACCGACGCCATCCTCGTATTGCTGCAAGCTCTGCCCCAGAACGTTCAAGGCGCGCAACAGCTTGGAAAATCATCTACTGATGAAGCACAAGGGTTCGAAAGGAGGGCCCGACATGCTGCGGACGCTGTGCGAGAAACCGTTCGAATCGAGAAATGACTTTTATCAACACCTGCATAATCGAACAGAAGTCAGACAGTACAAGTGCGACGTCTGCGGAAAAATCTGCGCCAACGAGGAAAATCTTCGTTTCCACATCACCCTGCACTCGCAGACGTTCCTGTGCCCCCACTGCGGCAAGATTTTCTCTACCAATTACTCGCTGAAACTGCACCTCCGCGTGCACACAGGCGAACGACCCTATCAGTGCAAGGAGTGCCTTAAATCGTTCGCCAGAACCACGTCGCTCAGAGTGCACGAGCTAACCCACACGGGGCAAAGGCCGTACGTTTGTGATATATGCGGGCAAAAATTCACTCAGAGGAGCAGCATGATGGTGCATCGTCGGAAACACCCTGGAAATCATCCACCACCTCCGCCTATGGTCCTGAGTAAACGGAAGAATAACGAGCATTAG
Protein Sequence
MHDLWIRAPGIVEGYANSKGNGGKDVDIKARPSRALSASSLAGQTRWIPIAVRESHKTDALINTTVKDDNERKRFCVICSVYFCRQRDYKRHMVMHSDLTPYKCETCHLTFKRLSGLAVHKRVHRGIVFTCDICGFATIKKSTLTMHRRKLHERDYSFPCNQCDKFFMSNADLQDHKSCHLGETFACDICEKVYSQKSYLKRHKHKMHDAHEPPKFKCDVCKKSFVSGSNLRNHAKVHLQVHQCSYCGKQFANNRNLTAHNRKHTGEKPYKCKVCTESFAALSTLTVHELTHTEEKPYLCDLCGKWFTQRSSMMVHRKTHPGSDTIPPPERSSIAETTRGQDRIDRVPYQVAIPVSSLAAHNSMLWKIEVDCDDGDSERTKAIVETEFDRGVPPGKRINDETVVESTKTVLVPVRDPVTRQVKNILVPVEVKDESGLNIIKSVLIPVQGGDGLVSYEIKRVVVPIQPVLSIPQRKQTDTRPGMNKNKWKQASNKNTKETEEKMKLEAEEREKEQIKKSGEEEERTTEGTQKSVPAEGVPNGDVDQVHILDTLRTTCPFCEKRYRDVDEMQKHVSKVHKKPYNCDKCRKGYFTDYALEEHQKTHELPSFYQCSICQLQYKTTSGLKNHRTREHTNLKPNFTCDYCGKRFKLKLDLALHINRSHMNATHICRFCGMAVKNIAHHELKHGHARKPTPSSYCCKLCPRTFKARNSLENHLLMKHKGSKGGPDMLRTLCEKPFESRNDFYQHLHNRTEVRQYKCDVCGKICANEENLRFHITLHSQTFLCPHCGKIFSTNYSLKLHLRVHTGERPYQCKECLKSFARTTSLRVHELTHTGQRPYVCDICGQKFTQRSSMMVHRRKHPGNHPPPPPMVLSKRKNNEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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