Basic Information

Insect: Noctua janthina
Gene Symbol: Bcl11a
Assembly: GCA_963576755.1
Location: OY755080.1:278786-293337[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2 1.6e+02 3.7 0.1 3 23 120 140 118 140 0.95

2 14 0.0021 0.16 13.1 2.8 1 23 279 301 279 301 0.99

3 14 8.5e-05 0.0067 17.5 0.2 1 23 307 330 307 330 0.96

4 14 0.0014 0.11 13.6 1.6 1 23 335 358 335 358 0.94

5 14 2e-05 0.0016 19.4 1.6 2 23 519 540 519 540 0.98

6 14 0.00021 0.017 16.2 3.2 1 23 546 568 546 568 0.98

7 14 3.4 2.7e+02 3.0 5.0 1 23 632 654 625 654 0.97

8 14 0.011 0.87 10.8 2.1 1 23 689 711 689 711 0.98

9 14 0.00024 0.019 16.1 2.3 1 23 717 739 717 739 0.98

10 14 0.2 16 6.9 7.3 1 23 748 770 748 770 0.98

11 14 0.00059 0.047 14.8 0.6 2 23 821 842 821 842 0.97

12 14 0.0055 0.44 11.8 3.9 1 23 859 881 859 881 0.96

13 14 1.8e-06 0.00014 22.8 0.7 1 23 887 909 887 909 0.98

14 14 6.1e-07 4.8e-05 24.2 3.1 1 23 915 938 915 938 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2	1.6e+02	3.7	0.1	3	23	120	140	118	140	0.95
2	14	0.0021	0.16	13.1	2.8	1	23	279	301	279	301	0.99
3	14	8.5e-05	0.0067	17.5	0.2	1	23	307	330	307	330	0.96
4	14	0.0014	0.11	13.6	1.6	1	23	335	358	335	358	0.94
5	14	2e-05	0.0016	19.4	1.6	2	23	519	540	519	540	0.98
6	14	0.00021	0.017	16.2	3.2	1	23	546	568	546	568	0.98
7	14	3.4	2.7e+02	3.0	5.0	1	23	632	654	625	654	0.97
8	14	0.011	0.87	10.8	2.1	1	23	689	711	689	711	0.98
9	14	0.00024	0.019	16.1	2.3	1	23	717	739	717	739	0.98
10	14	0.2	16	6.9	7.3	1	23	748	770	748	770	0.98
11	14	0.00059	0.047	14.8	0.6	2	23	821	842	821	842	0.97
12	14	0.0055	0.44	11.8	3.9	1	23	859	881	859	881	0.96
13	14	1.8e-06	0.00014	22.8	0.7	1	23	887	909	887	909	0.98
14	14	6.1e-07	4.8e-05	24.2	3.1	1	23	915	938	915	938	0.98

Sequence Information

Coding Sequence: ATGAACCAAGCAGCAGCAGCTATACCAGGGAACATGGATGTAGACCCGCTGCTCCCGTACGAGTACCCAGCGTACGACAGCTACGCGGCCCAGGCCTACCCATACCCCAGCAAGCTGCAGCAGTCCATCTACCAGGCTTACCAACAGACCAACACAAactatatcaacacacagccgcAAGAACCCGTCAGCAATCCACTACCAGCACCACCAACATCCATTGACATAGAGATCCcgcctaaaaatgaaaaaacagaCCCTGAACCAGTCTTAAAAAAGAGACGGAAGGAGAAGAACGGCCAGAAGAGTACTTATTGTTCTGAGAAGATCACGGATGCTGCGTTCAAGTTCTACGGTTGTGCGGTCTGTAATGTGAGTTACAATGCACTTCACGACCTTGACCAGCACGTGACCGTCCACAAGAACAGAATGACCAGTTACAGACTGCGGTTACGGaaccaatttaaaaagaaacaaattaagaaagaaaagaagaagttgaaaaagttggataaaattaagaaagaaaATGAGTTGGATGTGGACATCAAACCTGAGGACGGATATATTGGTGAAGAGAAGGCGacagattttattaataatggaATTAATCCAAATACTGAACTAAATggaaatgtaaataatgaaacTAGTGCAAGTGAAGCCCAGAAGAGTCAAATTACTACACATAATGATATAAATTCTACGAATAGCGACTCTCAGAGTAATGCAACTAATTGTTCAAGCAACGGTAATAGTGAAGACAATATACACAGCATGAACTGTAAGGACAACAGTATGGACGAAGCAGAGTTAAATAATTTAGAGAAAATTTACAAATGTTTTGCGTGTCAGAAACAGTTTACTTTGAGCTATTATTTGAAACTTCATGTGAGATCACATACGGACGAGAAACCGTACACGTGCGCGGTGTGCGGCCAGTCCTTCATCACGGCCAGCAAGCTCGGGCGGCACAACAAGCGCATCCACCTCGCCGAGCGCTACCAATGCCGCATCTGCTTCAAGGTCTACTCGCGGTTCGAGCTACTGACGGCACACTTCGACAAAACACATCCCGAAGACAAGCTGGAGGGAGAGCCGTATGACTACAACGCGATTCTGCCGTACCTGAAGGAGCTGGAGGAGCAGCTCCGCGTGCCAGAGCAGGACGGCGGGGCGGGCGAGCGGGACAGCAAGCCTCACGCCGACGAGCTGTTCTGGGAGCAGCAGCAGCCGGCGcgtgccgcggatcccgccgagATCAAGGAAGAGGCGCTCGACGAAGACCAGAAGGAGCTGGTGCCCAAACTAGACATACTGATCGAGGAGGTCAAAGTCGACTTCGACGTGCCGGTCAAGCGCGAGCTGACGGATGACGAGACGCCCGGCGACGGCGCCAGTGACGTCGGCGTCGGTGACGTGGGCGACGTCGGTGATGTCAAGGATGAAGATAGCCACTCCGACGAGGACTACTTCCCGGAGAACACGTGGGCAGCGCCCCCCGCCCCCTCGCCcgccccgccgcccccgccgcccgcgcgccgCGCGCCCCGCACCTGCGAGGTGTGCCACAAGAGCGTGAGCAGCGCGTCGTACATGCGCGTGCACATGCGCACGCACACGGGCGAGCGGCCCTTCAAGTGCTACACGTGCGGCCGCGGGTTCATCACCAGCTCCAAGATGCACCGCCACGTGCTCACGCATGCGCAAGACAAAGAGGAACTTAAAGCGGAAGGGGATGACACGAAACCGGAAGTGGCCGACGGAGCAGCGGGACAACAGGAACAAGATGGCGTCAAAAAACCAGCGAAGAAGAAATCCAAAATGAAGTCGAAAATGCCTAAAACGAAGAACAGCGAGGAAAAGCCGCGCCGCAAACACCAGAAGAGACCGCACGCTTGTGAGTTCTGCAACCAGAAGTTCCTGCACCTCAACATGCTGGAGGTGCACACGCAGTCGCACGCGGGCGAGGCGCTGGTGCTGCGCTGCCACTACTGCCTGCTGGCCGCGCCCGACGAGCCGGCCCGGCGCGCGCACGAGGCCACGCACTGCGGCGCCAAGCCCTACGTCTGCACGCTCTGCGGGAACACCTACAAGAAGCGGGAGACCATGGTGTACCACCGCAAGCGGCACTCGCCGGACGCGGAGTTCGTGTGCGACGTGTGCTCCAAGCGGTTCAGCGCCGCCTGCAAGCTGCGCAAGCACCTGCTCACGCACCGCCGCGACGCCTTCGTGCTGCGCTACGAGTGCCCCGTGTGCGCGCACATGTTCCACACCAAGTACCACGTGCACATGCACCTCAGCACGCACCAGAAGGAGGGCCTGATCTTAGAAGAGAACCGAAGCGAGATCCTCGCGATGGTACTACAGAACGCGCGCAAGATCCCGCGCGCCGGGCCCGCGCACGCGCacgccgcgcccgcgcacgcggcCGCGCTGCCGCCCGACGAGCGCTCGCGCGTCTGCAACATCTGCGGGGACGTCTTCTCACACTTTTACTACTTAGAAGAGCATTTGAAGAGCCACGGCTCAAGGATAAGCATCGAAGACATCGACAAGCAAGAAGAGAAGAAATACATTTGCACGATATGTAACAAAGGCTTCAAGTTGCACTATTATTTGAAACTCCACAGCTTCACGCACTCGAAGGAGAAGCCGTTCATCTGCCAGCAATGCGGGAAAGGATTCATCACGAAAGGCAAGTTGAAACGGCATCTGGAGACACATACGGGGCTGAAGAAGTATCAGTGCCACATCTGTTACAAGTTCTTCACGAGGCCGAGTTACCTGAGGATACATGTGAGGACTATACACGGGACTCAGGACTATAACTTCCGGTTCGACAAGGGCTACGGGCTGGGCTCGTTCGCGATGTCCATGACGGTGTCGGATGTGAGCCAGAATAGTGTTTAG
Protein Sequence: MNQAAAAIPGNMDVDPLLPYEYPAYDSYAAQAYPYPSKLQQSIYQAYQQTNTNYINTQPQEPVSNPLPAPPTSIDIEIPPKNEKTDPEPVLKKRRKEKNGQKSTYCSEKITDAAFKFYGCAVCNVSYNALHDLDQHVTVHKNRMTSYRLRLRNQFKKKQIKKEKKKLKKLDKIKKENELDVDIKPEDGYIGEEKATDFINNGINPNTELNGNVNNETSASEAQKSQITTHNDINSTNSDSQSNATNCSSNGNSEDNIHSMNCKDNSMDEAELNNLEKIYKCFACQKQFTLSYYLKLHVRSHTDEKPYTCAVCGQSFITASKLGRHNKRIHLAERYQCRICFKVYSRFELLTAHFDKTHPEDKLEGEPYDYNAILPYLKELEEQLRVPEQDGGAGERDSKPHADELFWEQQQPARAADPAEIKEEALDEDQKELVPKLDILIEEVKVDFDVPVKRELTDDETPGDGASDVGVGDVGDVGDVKDEDSHSDEDYFPENTWAAPPAPSPAPPPPPPARRAPRTCEVCHKSVSSASYMRVHMRTHTGERPFKCYTCGRGFITSSKMHRHVLTHAQDKEELKAEGDDTKPEVADGAAGQQEQDGVKKPAKKKSKMKSKMPKTKNSEEKPRRKHQKRPHACEFCNQKFLHLNMLEVHTQSHAGEALVLRCHYCLLAAPDEPARRAHEATHCGAKPYVCTLCGNTYKKRETMVYHRKRHSPDAEFVCDVCSKRFSAACKLRKHLLTHRRDAFVLRYECPVCAHMFHTKYHVHMHLSTHQKEGLILEENRSEILAMVLQNARKIPRAGPAHAHAAPAHAAALPPDERSRVCNICGDVFSHFYYLEEHLKSHGSRISIEDIDKQEEKKYICTICNKGFKLHYYLKLHSFTHSKEKPFICQQCGKGFITKGKLKRHLETHTGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQDYNFRFDKGYGLGSFAMSMTVSDVSQNSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00928932;
90% Identity: iTF_01063080;
80% Identity: -