Basic Information

Insect
Noctua comes
Gene Symbol
-
Assembly
GCA_963082995.1
Location
OY720296.1:5247243-5251066[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.041 3.2 9.0 0.3 1 23 84 107 84 107 0.91
2 10 0.33 25 6.2 0.2 2 23 134 156 133 156 0.94
3 10 0.00028 0.022 15.8 2.8 2 23 179 200 178 200 0.97
4 10 1.9 1.4e+02 3.8 1.0 1 14 204 217 204 226 0.85
5 10 0.011 0.86 10.8 4.7 1 23 231 254 231 254 0.97
6 10 0.037 2.8 9.2 1.5 2 23 262 284 261 284 0.93
7 10 4.3e-05 0.0033 18.4 1.2 2 23 292 314 291 314 0.96
8 10 0.00046 0.035 15.2 0.8 1 23 320 342 320 342 0.98
9 10 4.1e-06 0.00031 21.6 2.7 1 23 348 370 348 370 0.99
10 10 2.1e-05 0.0016 19.4 4.5 1 23 376 399 376 399 0.98

Sequence Information

Coding Sequence
ATGCTCGACTTAAGAGAGTTAGATCGATATGAGGATGTAACAAAACCACAATGCGCCTGTGTTCAACGTTACGTGAATGCCAAGATTGAAACGGATTGTGACAAAAAAGTCACTCGCAAACGTACCCGAGGAAATCTCAAACAACCTGAGGAGCTCAAAATTAATGAGTTATTAAAACATAGAAGCAATATACGTCTTATATTACAATGTACCAACGCAACCCCTATACGATGCAGAGGGGGCATCGGGTACGCCTGTTGTTTTTGCGCAGATGAGTTTCCAGATCCTTctgacttaaaaaaacatactcTAGAAGGCCACGACGATAAAACCAAACTCAAATTCATGGTTGGCAAAATGATGTTCTCATTCCTTGTCAAATTAGACATTACTGATCTTACGTGCAAAATATGcgaaaacagcattcattcattAGAAGATCTCGTAGATCATTTGATCAAAATACACGATAAAAAGATTTACACTGATATTAAGAGCCACATAATGCCTTTTAAGTTCGACAGTGATACACTAAGATGCATGGTCTGCCAACATGTTTTcaacaaattcaaaaacttGCAACAACATATGAACGTACATTACAGAAATTTTGTTTGCGAATTTTGTGATGCTGGATTCATAAATAAACACATTCTAGCATGTCACACCGAAGGGCATAAGACTGGTACTTTCAAATGTGATTTATGTACGAAAGTATTCGATACCCATAGAAAGAAGAAAAGTCACGAAAAAACCGTTCATATTCATGCGAACTTGCTCAGTAAATGCGGGTACTGTAATGAGAAGTTTACGAATTACAAAAAAAGGGATGATCACTTACTCAAGGTCCATGGAGTTCAGATTAAAGCCGTCAAATGCAACGCGTGTGACAAGTCTTTTGACCACAAAGGCGCACTAACGATCCACACGAAACGAGATCACCTGATGGAGAGACGCTACAAATGTGCTCAGTGCGACATGAAATTTTTCGGATCAAACGAATTAAAACTCCACATGGTAAAACATACAGGAGTGAGGGAGTTCAAATGTAGTGTCTGCTTCAAGTCATATGGCcggaagaaaacattaaaagaGCATATGAGGATACATAACGACGATAGGCGGTTCAAGTGCGAGCACTGCGGTCAGGCATTCGTGCAGAAGTGCAGCTGGAAAGGGCACATGAGGACTAGGCATGGCACACTTGTctga
Protein Sequence
MLDLRELDRYEDVTKPQCACVQRYVNAKIETDCDKKVTRKRTRGNLKQPEELKINELLKHRSNIRLILQCTNATPIRCRGGIGYACCFCADEFPDPSDLKKHTLEGHDDKTKLKFMVGKMMFSFLVKLDITDLTCKICENSIHSLEDLVDHLIKIHDKKIYTDIKSHIMPFKFDSDTLRCMVCQHVFNKFKNLQQHMNVHYRNFVCEFCDAGFINKHILACHTEGHKTGTFKCDLCTKVFDTHRKKKSHEKTVHIHANLLSKCGYCNEKFTNYKKRDDHLLKVHGVQIKAVKCNACDKSFDHKGALTIHTKRDHLMERRYKCAQCDMKFFGSNELKLHMVKHTGVREFKCSVCFKSYGRKKTLKEHMRIHNDDRRFKCEHCGQAFVQKCSWKGHMRTRHGTLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01085784;
90% Identity
iTF_01065024;
80% Identity
-