Basic Information

Insect: Nineta flava
Gene Symbol: Bcl11a
Assembly: GCA_963920215.1
Location: OY986045.1:62982204-62984440[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0016 0.059 14.4 1.8 2 23 233 254 232 254 0.96

2 12 0.00068 0.025 15.5 2.3 1 23 262 284 262 284 0.97

3 12 0.016 0.6 11.2 1.9 1 23 290 313 290 313 0.88

4 12 0.0044 0.16 13.0 1.7 2 23 319 340 318 340 0.97

5 12 8.1e-06 0.0003 21.6 0.8 1 23 345 367 345 367 0.98

6 12 1e-05 0.00038 21.3 1.6 1 23 373 396 373 396 0.97

7 12 0.001 0.038 15.0 0.6 3 23 405 424 404 424 0.97

8 12 0.0039 0.14 13.2 0.3 1 23 430 453 430 453 0.93

9 12 9.1e-05 0.0034 18.3 0.2 1 23 462 485 462 485 0.95

10 12 5.2e-05 0.0019 19.1 0.5 2 23 492 514 491 514 0.96

11 12 0.00026 0.0096 16.9 5.0 1 23 520 542 520 542 0.97

12 12 2.4e-05 0.0009 20.1 0.3 1 23 548 570 548 570 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0016	0.059	14.4	1.8	2	23	233	254	232	254	0.96
2	12	0.00068	0.025	15.5	2.3	1	23	262	284	262	284	0.97
3	12	0.016	0.6	11.2	1.9	1	23	290	313	290	313	0.88
4	12	0.0044	0.16	13.0	1.7	2	23	319	340	318	340	0.97
5	12	8.1e-06	0.0003	21.6	0.8	1	23	345	367	345	367	0.98
6	12	1e-05	0.00038	21.3	1.6	1	23	373	396	373	396	0.97
7	12	0.001	0.038	15.0	0.6	3	23	405	424	404	424	0.97
8	12	0.0039	0.14	13.2	0.3	1	23	430	453	430	453	0.93
9	12	9.1e-05	0.0034	18.3	0.2	1	23	462	485	462	485	0.95
10	12	5.2e-05	0.0019	19.1	0.5	2	23	492	514	491	514	0.96
11	12	0.00026	0.0096	16.9	5.0	1	23	520	542	520	542	0.97
12	12	2.4e-05	0.0009	20.1	0.3	1	23	548	570	548	570	0.98

Sequence Information

Coding Sequence: atggaattaacaAATGTTTCATCAATTAGTTTAACAGATTTTAATACAATATGTCGTGTTTGTTTAGTTGCACGCTCAAATATGGTATCCATATCAACGGCACAAATTTTACATATGTTAGAAGAATGTACTTCTGCAGATGACGATTGTAATGGAAAACTACCAcaacaaatatgtaaaaattgtttttggcaACTGAAAAATGCCTACCATTTCAAACAACAATGTACGATTTCATTGGACATTCTACGAAATATTCTAAACAGTGATAAcgaaaatactgaaaataaagcTGAATCTCAAGATGATAGCATCATATCTGCGGTTAAAGTTGAAGTAATCGAAGCTATTGAAGATTTTAATAAACTGAATACAAGTAACAATTCGgatgtaaatgaaaatttagatgtgaAAAAGGAATCATCCAATTACACATTTAATTCGGACTTCAATGAGTATGTGACCAACTCGAAAAATAGTGATTTTGATGATTTAAAGGATTCTTTAAACAATGATGAATATTTGGATGATGATTCCTCACTATCAAACGATGACGACTGTAAGGACGAAAGCACAAATGACGAATCCAAAGACGAGGATAACAATTTACCAAACGAACAAACAACACAAACACgggaacaaaaacaaaaatctgtCGCCGATTTACTaatcaaaaaatacaatatcTACGGTTTAACATGTAACATATGCCATAAGGATTTGAGTAATCGATTTTCAATGCTTCGACATATGGAAGTTCACGATCAAAATCGATCCTTAAAATATCACTGTAAAACGTGTAACAAAGGATTTTATGCggctgaaaatttaaaaaaacatgaaatcCGTCATTTAGGCAAAACAAAGTACCAATGTGATAAGTGTCCTAAAAGATTTTACGTGTTAAGTGCTCTGGGGGTACATTGTAAGTCTAGTCACAAAGCGAAACCAATCACATGCACACAATGCCCTCAACAATTCTATCATCAACTACAAATCGAACAACATATGCAAACACATGAggagaaaaaatttgtatgcgaagattgtggaaaaattttcccCACACGTAATCgtttaacaaaacataaaaaaatccaTTCAGATGAACGACCCTACAAATGTGACATGTGCGACAGTGCGTTTAaacagaaatttaatttaacaattcaTATGAAATTGCGGCATCTAGAAACCGATCGACGTGAAATGTGTAATGTTTGTGGTAAATTATTTCATCCGGGTAGTTTACGCGCTCACTTAGAGACACACAACACCGATACGATTTACAAGTGCAATGAATGTGGCAAGATTTATGCAAATCGGATTATTTTAGGTAAACATattaatcaaaaacataaaaatggtggaacatcgaaaaaatattattgtaatatatgtaataaagcGTTAGGGAGTTCGGGTAGTTTACGTAAACATATGGTCGTAATGCATACAACGTTAGAGAAAAGTGAATGTCATATTTGTGGTAAATCATATAAATCGCAGAATGGCGTTAAGGTGCATATTTTAAGTGCAcacatggatgaacgtcctcaTATTTGTCAAACGTGTAACAAAGCGTTTCATTCGAAAAATGTGTTGGAGAAACATATGCGTACGCATACCGGCGAACGACCATTTCCTTGTAATGTTTGTGGGAAGGCGTTTGGATTTAAACAAGTATTAAAAACACATATGAAAATTCatgctaaataa
Protein Sequence: MELTNVSSISLTDFNTICRVCLVARSNMVSISTAQILHMLEECTSADDDCNGKLPQQICKNCFWQLKNAYHFKQQCTISLDILRNILNSDNENTENKAESQDDSIISAVKVEVIEAIEDFNKLNTSNNSDVNENLDVKKESSNYTFNSDFNEYVTNSKNSDFDDLKDSLNNDEYLDDDSSLSNDDDCKDESTNDESKDEDNNLPNEQTTQTREQKQKSVADLLIKKYNIYGLTCNICHKDLSNRFSMLRHMEVHDQNRSLKYHCKTCNKGFYAAENLKKHEIRHLGKTKYQCDKCPKRFYVLSALGVHCKSSHKAKPITCTQCPQQFYHQLQIEQHMQTHEEKKFVCEDCGKIFPTRNRLTKHKKIHSDERPYKCDMCDSAFKQKFNLTIHMKLRHLETDRREMCNVCGKLFHPGSLRAHLETHNTDTIYKCNECGKIYANRIILGKHINQKHKNGGTSKKYYCNICNKALGSSGSLRKHMVVMHTTLEKSECHICGKSYKSQNGVKVHILSAHMDERPHICQTCNKAFHSKNVLEKHMRTHTGERPFPCNVCGKAFGFKQVLKTHMKIHAK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00333104;
90% Identity: iTF_00333104;
80% Identity: -