Nlug002123.1
Basic Information
- Insect
- Nilaparvata lugens
- Gene Symbol
- lola
- Assembly
- GCA_014356525.1
- Location
- chr5:50550172-50585092[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.00042 0.065 14.2 1.9 1 21 100 120 100 121 0.96 2 19 0.019 2.9 9.0 4.1 1 23 129 152 129 152 0.94 3 19 0.0022 0.35 11.9 0.4 1 17 209 225 209 226 0.92 4 19 1.4e-05 0.0022 18.8 2.1 1 21 263 283 263 284 0.95 5 19 0.00045 0.071 14.1 0.4 3 21 332 350 331 351 0.94 6 19 0.061 9.6 7.4 1.4 1 17 359 375 359 376 0.95 7 19 2.3e-06 0.00036 21.3 1.3 1 21 407 427 407 428 0.96 8 19 0.0022 0.34 11.9 3.2 1 23 436 459 436 459 0.95 9 19 0.065 10 7.3 3.8 1 20 566 585 566 586 0.95 10 19 0.019 2.9 9.0 3.3 1 21 595 615 595 620 0.94 11 19 0.028 4.3 8.4 2.6 1 21 642 662 642 663 0.92 12 19 0.00027 0.043 14.7 2.5 1 21 673 693 673 694 0.94 13 19 0.00033 0.051 14.5 0.3 1 21 725 745 725 746 0.94 14 19 8.4e-06 0.0013 19.5 1.6 1 21 787 807 787 808 0.96 15 19 0.0025 0.39 11.7 2.0 1 23 816 839 816 839 0.95 16 19 0.098 15 6.7 0.0 2 21 852 871 851 872 0.93 17 19 9e-06 0.0014 19.4 0.9 1 21 880 900 880 901 0.95 18 19 0.01 1.6 9.8 0.4 1 21 949 970 949 971 0.93 19 19 0.0018 0.28 12.2 0.3 2 23 980 1002 979 1002 0.92
Sequence Information
- Coding Sequence
- ATGAATAAATTACAGTTCATCATATTGAGTCATCCTTTTTTTTCTTATGTGTTTTTTTCTTCGCAACAACTACATTCCAAATCGGTTGTAGAGTTCTTAAAAAAACATTTTCCTTACTTTTTGAATAATTTTCATCCTCAGAATAATATTATGGATTCAACTATATCCAAAATGAAGAGAACATTAATTTACTATGAGGAGAGCAGTCCATTCCAAGTTCAATCAGACATCCAACAACAGACATCAGACATCCGCCTTCCGACCGCCGACAATCCGGCGAACATTGATGGAAGAAAGTTCAAGTGTGAACAGTGCGGAAAGCTGTACAAACATCTCACCACCTTGAAGAATCACTTGAACAATGAGTGCGGAATGGAACCGCAGTTCAAATGTCAATTCTGTTCGTTTGCAACAAAAAGAAAGACTACCTTGAAAACTCACATTTTCTTGAAACATCAGGAATTGTTAAATAAACTTAATCTGTTATCAGATATCAATTGTGAAGAGAACTTTTTCTATGAGGAGAGAAGTTCAATCCTATTAGTTCAATCAGACATTCAACATCTGATGTCAGATACCCGGCTTCCGACATCCGAAAATGAAGCGAACTTTGATGGAAGAAAGTTCAAGTGTGAACAGTGTGGAAAGGTGTACAAACATCTCACCACCTTGAATGCGAAAGAGAACCGCAGTTCAAATGTCATTTCTGTTCGATTCATTCACTACGAGGATGCTCTATCACCCAGCTACGATGCTCTTGTAGATTCAGAAAACGATGAGAAAAAATTCAAATGCAACAAGTGCGGAAAAGCCTACAAGCATCAACAATCGCTCAATAATCACGTGAACTATGAATGCGGCAAGACACCACAGTTCAAATTGTTTTTCGACGCGGTTGGGAACGAGTATGTGAACCATGGAGATTATTTTGAGAACAGCGCTCTTTCAGCAGACTTCATTATTCCAGAAACCCTCAACAATGATAAAGTTGCGTGCGAAAATTGCGGAAAATCTTTCAAGAACAGGAATACAATGTGGACTCATGTGAAATTCGATTGTGGCAAAGAGCCTCAGTTTAAATGTCAAATGTGTCCGTTTTCGAGCAAGCGGAAAAACAATTTGAAAAGTGGTTCGTTCTTTGCTGAGGGATACTTGGCTCCAAGGATCTGTGGGAGTGGTGATCCTCTGAAGGCCATCCTCAGTCAAGGCGGCAAAAACTACAAGTGTCCCAGATGCGGCAAGAGCTATCAGTCTTCGAGCAACCTCAAGTCGCACTTGAAATTCGAGTGTGGTCTTGAGCCACGCTTCTCTTGTCCCTACTGCTCGCACCGCAGTAAGCTCAAAGGAAATCTCAGGAAGCATATCTTCATCAAGCACAGCGGTTCAGTTCTCAAGAGTACCGAACCACTGGTCAAACTTGAACAAAACTCTGGGTCAGAAATGAACTACGACGATGATGGAAGAACGAGTGACGAGGAGAGTCTCTGCATCTCGCAGTTTGTCGTCGTAGAAGATGGTGAGGGGGCTTGGGAGGGGGCGGAGTTGGAAGAGGGGGATTCCACCCCCACCGCCACCCCCGAGACAGCCATGAACCTCTCGGCGCGAAGATGGACCACTGAGGAGGCGACCTCCTCCTCATCTGACATCTCTCCTACGGCGAGCGGTCCTCAAGGCTGTGGAGGGGCGAATGGTACGCACAAGTGTCCCTTCTGCCTGAAATGCTACAAGCAGATCAAGTCACTCAAGTACCATGTGGTGTGGGAGTGCAAGAAGGAGCCCACTTTCAAATGCGACGATTGCAATTTGAAGTTCTACTATCCGTTCACCTACAGCAAGCACAAGAAGTATAATGTGTCTCACGAAAATAATATTTGGTCTCAACCAAAAACGAGACGGGAACAATTTGAAGTCAAGCAGGGTCGTTTCCTTTGTCCAAGATGCAGCAAAAACTACAAATACAAGGCTGGACTGCACCAACATCTGAAACACGAGTGTGGAGTCGAACCAAGATTCAAATTTTTTTGTCCTCAGTGTGGTAAAAACTATAAATACAAGAAAGGACTCAACCAGCATTTGAAGCACGAATGCGGAATGGAACCCAACCTCAAGTGTTCTTTCTGTTCATTCAAGTGTAGGCACAAGTTTCACATGAGAGCCCATGGCAGCCAGGGCCATTGCTGCCCGAACTGCGGCAAGGCGTACAGCTGGCTGGGAAACCTGACTCGGCATCTGCGCTACGAATGCAACAAGGCGCCTCAGTTCGCCTGCCCCGTCTGCAAGCGCATGTTATATTGTATCATGTACAATTTCCTGGACACTTTCTCGCTGTCCGAGTTTGACATCCTGTCGCAAGAGCAGTTTGTCTGCGAGAAGTGCCAGCGCGTGTACACGCACCAGAGGTCGCTGCAGCGGCACATGAAGGACGAGTGCGGAGTGCCCCCCAAGTTCACCTGTCAGCTGTGTCCCTATGCCACCTCGCGCAAGACAAGCCTCAAGCTCCACTTCAACAATAAACATGTGCTCAGGGAGATGCCCACTGATTCGCAGGGCTTGCAGTGTGATGGCTGTGAACGTGTGTACGGCAGCCTTGGTTCGCTGGGCTACCACAGACGATACGAGTGTGGCAAAGAGGCGCGTTTTCAGTGCACATTCTGCGGCAAGAAGAGCAAACGCAAGAGCAACATGCGCGCGCACATGGCCTCTTGTCCCATGAACGTTGATCTTTTTTTGCATATATATGCTACCCACTGGTCGGCTGCAGATGCTGTGAACTACGCAGACGAAGATGCGCCGTGGTCGAATGCGGTTGCAGACGGCAAGTACCCACGTGACAGCCGAGGTCGCTACGCGTGTCCGAATGCGTGCGGTCGCAGCTACAAGTACGAACGAGGTCTCAAGCAACATCTCAAGCATGAGTGTGGACTCGAGCCCAACGTAAAATGCCCCCTGTGCCCCGTCGTGACCCGGCACAAGTCCAATATTAGAGCGCACATAGTCAACAAGCATCCTGATTTTTATTGTGATAACGGAAAGATTATTTAA
- Protein Sequence
- MNKLQFIILSHPFFSYVFFSSQQLHSKSVVEFLKKHFPYFLNNFHPQNNIMDSTISKMKRTLIYYEESSPFQVQSDIQQQTSDIRLPTADNPANIDGRKFKCEQCGKLYKHLTTLKNHLNNECGMEPQFKCQFCSFATKRKTTLKTHIFLKHQELLNKLNLLSDINCEENFFYEERSSILLVQSDIQHLMSDTRLPTSENEANFDGRKFKCEQCGKVYKHLTTLNAKENRSSNVISVRFIHYEDALSPSYDALVDSENDEKKFKCNKCGKAYKHQQSLNNHVNYECGKTPQFKLFFDAVGNEYVNHGDYFENSALSADFIIPETLNNDKVACENCGKSFKNRNTMWTHVKFDCGKEPQFKCQMCPFSSKRKNNLKSGSFFAEGYLAPRICGSGDPLKAILSQGGKNYKCPRCGKSYQSSSNLKSHLKFECGLEPRFSCPYCSHRSKLKGNLRKHIFIKHSGSVLKSTEPLVKLEQNSGSEMNYDDDGRTSDEESLCISQFVVVEDGEGAWEGAELEEGDSTPTATPETAMNLSARRWTTEEATSSSSDISPTASGPQGCGGANGTHKCPFCLKCYKQIKSLKYHVVWECKKEPTFKCDDCNLKFYYPFTYSKHKKYNVSHENNIWSQPKTRREQFEVKQGRFLCPRCSKNYKYKAGLHQHLKHECGVEPRFKFFCPQCGKNYKYKKGLNQHLKHECGMEPNLKCSFCSFKCRHKFHMRAHGSQGHCCPNCGKAYSWLGNLTRHLRYECNKAPQFACPVCKRMLYCIMYNFLDTFSLSEFDILSQEQFVCEKCQRVYTHQRSLQRHMKDECGVPPKFTCQLCPYATSRKTSLKLHFNNKHVLREMPTDSQGLQCDGCERVYGSLGSLGYHRRYECGKEARFQCTFCGKKSKRKSNMRAHMASCPMNVDLFLHIYATHWSAADAVNYADEDAPWSNAVADGKYPRDSRGRYACPNACGRSYKYERGLKQHLKHECGLEPNVKCPLCPVVTRHKSNIRAHIVNKHPDFYCDNGKII
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -