Basic Information

Insect: Nicrophorus vespilloides
Gene Symbol: ham
Assembly: GCA_001412225.1
Location: NW:46783-114876[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0011 0.074 13.0 2.9 1 23 276 299 276 299 0.96

2 8 5.4e-08 3.7e-06 26.5 4.3 1 23 305 327 305 328 0.96

3 8 1.1e-06 7.5e-05 22.4 1.0 1 23 334 356 334 356 0.95

4 8 1.9e-05 0.0013 18.4 5.0 1 23 362 384 362 384 0.99

5 8 0.0042 0.29 11.1 1.1 2 21 392 411 391 412 0.95

6 8 4.5e-09 3.1e-07 29.9 1.2 1 23 703 725 703 725 0.99

7 8 8.5e-07 5.8e-05 22.7 1.6 1 23 731 754 731 754 0.97

8 8 8.8e-05 0.006 16.4 5.3 1 23 760 782 760 782 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0011	0.074	13.0	2.9	1	23	276	299	276	299	0.96
2	8	5.4e-08	3.7e-06	26.5	4.3	1	23	305	327	305	328	0.96
3	8	1.1e-06	7.5e-05	22.4	1.0	1	23	334	356	334	356	0.95
4	8	1.9e-05	0.0013	18.4	5.0	1	23	362	384	362	384	0.99
5	8	0.0042	0.29	11.1	1.1	2	21	392	411	391	412	0.95
6	8	4.5e-09	3.1e-07	29.9	1.2	1	23	703	725	703	725	0.99
7	8	8.5e-07	5.8e-05	22.7	1.6	1	23	731	754	731	754	0.97
8	8	8.8e-05	0.006	16.4	5.3	1	23	760	782	760	782	0.99

Sequence Information

Coding Sequence: ATGAGGTCCAAGAGCATCGCAAGGAAAATCACTTCCCACGAAGGTAGCGAGGATGAACTAGAGATTCCGCGTGGTGGTAACGAGGATATGGAGACGATGGTATCGCCGAATTCCGGGGATTTGGCCGGAGAGAGGTTACAGCTGAAGCCGGTTGAAGCACTCTACGACACGCATCATAGGCCCTCCGTCGATGATCCCTACAAGTTCCTCACGATTCACGCGAAGAATATCTTGGCGGAACACTTTTCCGGGATCAAGATGGCTAATGATTACGCTTGGTCGCGTCTCCTACCTGCTGATCTCGAGATCAGGGAAAACGGAGTCTTCGCCAAGTGTCCTCTTGCCAAACACATCAAGTACGGACCCTTCCAAGGGAAATGGGCCGGTATTCCTCAAGACAAACGATTCGCTTGGGAGgtgaTTGCGGGATCAGGAGATAGGGGTTGGTTGGACGGATCCCTCGAGCATCAGAATTGGTTGAAATTCATCAAGTGTTCGACGACGAAGAGCTCGGCCAACATGAGGCACTTCCTGCAGGGCGGAAAATTGTGGTACGAAACATGCATGGATATACCATCTGGTGCCGAATTAATTTTGGAACCGCGGGAACCGCTCTACCTGCAGGACATGTTCGGGGATTCCACCTCTGCAGACGAAAGGTCCGATCGCGAAACCGCTTCTCAACACAGTGGTACCGTTGAAGACGAAAGAGAAGACGAGGATGAGGATGCGCCCAGCCTGTGTTGCGTGTGCGATCAGCCTTACCATAATATAGATAGATTGGACGAACACTTGGTGCTCAAGCACAACTACAGGAAGGACGAGTACCGCTGCGACTTGTGCCCGAAGGCGTACTGTTACAGACCTTGCTTGATCAGACACAGATCCATCGTTCACGGGGAGCACAGGAAGTACCACTGCGAGAATTGCACTAAGGTTTTCACCGATCCTAGTAATCTGCAAAGACATATTAAGACTCATCATCCGGCTGCCAGATCGCACGCGTGTCCTGAGTGCGGTAAAGCGTTTGCGACTTCTTCGGGATTGAAGCAACACACCCACATCCATTCGAGCGTCAAGCCTTTCCAGTGCGAGGTTTGCTTCAAAGCTTACACTCAATTCTCAAACCTGTGCCGTCACAAGCGGATGCACGCCGACTGCCGCATGCAGATCAAGTGCGTCAAGTGCAGCCAAACGTTCTCGACGGTCACCTCTTTGTCGAAGCACAAGAGGTTCTGCGATTCGACCACCCCTAACAACTCGAACTTGCCCATCCACCAAATGCCCATCAATCCGATGTCCACAAACAACATCCACATGTATCGACCGGCGCCTTGTCCACCTTTGCCCTTCTTCACTCGACCCTTCTCCGCCTACCACCAAATCTTCCACCCCAACGCACCGCAAGCGCCGTACATGAACCCGCTCCTCTTCAATCCACCACCGAAGCTTCCCAAAGAAGACGTGTCGCCGCCGAAGAAGCTGAGGTTAGCCAGCCCCGAGAGGATGTCACCGATTAAAGATAGAATGACCCCACCGCGCGTTCCCGCCATTACCAATACGAAAGTGAGTCCTCCAACGGCGGAGGAAGCGAATTTGGCGCCGAGCCCAGCGCGTCCACCACAAAACAGCACGATATTCCGCGATCCCCGGGAACAACTCAACACGAATACCTCGGACGAGGAGGAAACCTTCCCCAAAGACCTATCCACCGGCAAATCTCCCGCCCACAAATCGTGCAGCAGCGACGAGGAAACCGAAAAACCCTTGGACCTGAGCTGCTGGAAGAAGGAAGTGAAAGTCGAGGAGAAGGTCGAAGTGGTCGAGCTCATCGAAGCCCCAGTCAAAGAGGAGGAACCTAAGCTGATTTCACCACCACCCATCGCCTATCCGACACCTTACCATCCGATGCTCATGTATAGACCGAACTTGAATTTCCAAAACAACGAGAGGGTGTTCACGCCGTCTTTCCTCCCGCCTCGGCTCAACTACCTGAACCACCTGCAGCAACGCAACATCGACCTGCTCAGATCACCGACCTTCAGTGGAGTGCGGCAGTACCAGGACGTGATCAGTCAACAGAGTCAAGGCAAGGTGAAGGATCGGTATTCCTGCAAATTCTGCGGTAAGGTTTTCCCCCGTTCCGCAAACCTCACGCGCCACCTCCGCACACACACCGGGGAGCAACCCTACAAGTGCAGATACTGCGAGCGCAGCTTCTCCATCAGCTCAAATCTGCAGCGCCACGTGCGAAACATACACAATAAGGAGAAACCCTTCAAATGCACGCGGTGCGAACGCTGCTTCGGGCAACAGACGAACCTCGACAGACACCTGAAAAAGCACGAAACGGACGAGAACGGTGGCATCTCCGTCGCCGATTCCCCGGGAAGCAGTAACGAGAACGAGCGTGACGATGCCTGCTTCGAGGAGATCAGGAACTTCATGGGCAAAATCACCTGCTCATCGGATCCCTACTCTCAAACCAGGCTCTACACGCCTCCTCACAACAACCAAAGTGGAGTGATCGACGTCGTTGGACGCGATGACGATGACTCCGAGACGTACTCGGAAGGATCGCCTCCGGAAGACTTCTCCAAGCACGCGAAGGACGAAATCCTCAACAACAACGACCTCGAAATTTccacttaa
Protein Sequence: MRSKSIARKITSHEGSEDELEIPRGGNEDMETMVSPNSGDLAGERLQLKPVEALYDTHHRPSVDDPYKFLTIHAKNILAEHFSGIKMANDYAWSRLLPADLEIRENGVFAKCPLAKHIKYGPFQGKWAGIPQDKRFAWEVIAGSGDRGWLDGSLEHQNWLKFIKCSTTKSSANMRHFLQGGKLWYETCMDIPSGAELILEPREPLYLQDMFGDSTSADERSDRETASQHSGTVEDEREDEDEDAPSLCCVCDQPYHNIDRLDEHLVLKHNYRKDEYRCDLCPKAYCYRPCLIRHRSIVHGEHRKYHCENCTKVFTDPSNLQRHIKTHHPAARSHACPECGKAFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCSQTFSTVTSLSKHKRFCDSTTPNNSNLPIHQMPINPMSTNNIHMYRPAPCPPLPFFTRPFSAYHQIFHPNAPQAPYMNPLLFNPPPKLPKEDVSPPKKLRLASPERMSPIKDRMTPPRVPAITNTKVSPPTAEEANLAPSPARPPQNSTIFRDPREQLNTNTSDEEETFPKDLSTGKSPAHKSCSSDEETEKPLDLSCWKKEVKVEEKVEVVELIEAPVKEEEPKLISPPPIAYPTPYHPMLMYRPNLNFQNNERVFTPSFLPPRLNYLNHLQQRNIDLLRSPTFSGVRQYQDVISQQSQGKVKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCRYCERSFSISSNLQRHVRNIHNKEKPFKCTRCERCFGQQTNLDRHLKKHETDENGGISVADSPGSSNENERDDACFEEIRNFMGKITCSSDPYSQTRLYTPPHNNQSGVIDVVGRDDDDSETYSEGSPPEDFSKHAKDEILNNNDLEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01058616;
90% Identity: iTF_01058616;
80% Identity: -