Basic Information

Insect: Nicrophorus investigator
Gene Symbol: zfh1
Assembly: GCA_963457615.1
Location: OY735145.1:12792543-12797924[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0034 0.31 11.8 0.6 2 23 50 72 49 72 0.93

2 9 0.0012 0.11 13.2 0.2 3 23 109 129 107 129 0.95

3 9 4.3e-05 0.0039 17.8 0.7 2 23 136 157 135 157 0.97

4 9 4.2e-06 0.00038 21.0 5.9 1 23 166 188 166 188 0.99

5 9 0.00012 0.011 16.4 0.8 1 21 194 214 194 215 0.94

6 9 0.29 27 5.7 0.5 2 20 430 448 429 450 0.91

7 9 1.7e-05 0.0015 19.1 1.4 1 23 817 839 817 839 0.95

8 9 0.00012 0.011 16.4 9.4 1 23 845 867 845 867 0.98

9 9 0.048 4.4 8.2 7.1 1 21 873 893 873 894 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0034	0.31	11.8	0.6	2	23	50	72	49	72	0.93
2	9	0.0012	0.11	13.2	0.2	3	23	109	129	107	129	0.95
3	9	4.3e-05	0.0039	17.8	0.7	2	23	136	157	135	157	0.97
4	9	4.2e-06	0.00038	21.0	5.9	1	23	166	188	166	188	0.99
5	9	0.00012	0.011	16.4	0.8	1	21	194	214	194	215	0.94
6	9	0.29	27	5.7	0.5	2	20	430	448	429	450	0.91
7	9	1.7e-05	0.0015	19.1	1.4	1	23	817	839	817	839	0.95
8	9	0.00012	0.011	16.4	9.4	1	23	845	867	845	867	0.98
9	9	0.048	4.4	8.2	7.1	1	21	873	893	873	894	0.96

Sequence Information

Coding Sequence: ATGGTGGCGCGAAGTGAGAGCATGTTCGGGTGCTACGACAGCTACTCTTATAGACTTTGGAGTCTCGCCAATGTGTGGAACACCTGTCAATTACCCTCCCTCACGAATGGGGTGAGCAAAGAGGGCGAGGAGGGTGAATACTTCATCAAGTGTCCGCTATGCCAGAAGGGTTGCCAAACGTTGCAATCGCTGAAGGATCACATGGAGGCAGCCCATCCGGAGGCGTACATCGAACCGGGAAATTTGCAGACGACTCCGAGCGCCGTTTCGCCGACGCCGAGTCTCGGTGGAGGTGCTGGAATCGGCGGAATCGGTCCCTACGGTTGCTCCCAATGCGCCACGTCCTTCGCCAGCAAAGATCAATTGGAGAAGCACGAGTTGCTGCACTCTGCAAACGCACAAGTGACTTGTAAAATTTGTAGCAAAAACTTCGCGAACGTGTACCGACTACAAAGACACATGATTAGCCACGACGAGAGCGCGGTTTTGAGGAAGTTCAAATGCACGGAATGCGAAAAGGCGTTCAAGTTTAAGCATCATCTGAAGGAGCACATCAGGATACACAGTGGCGAGAAGCCGTTCGCGTGCGGGAACTGCGGCAAGAGGTTCTCGCACTCTGGCTCGTATTCCAGCCACATGACGTCCAAGAAGTGTTTGGTGATGAATCTGAAGTTGGGAAGGACCAGAGCACCGACGACGACGGCGTCCGGGGTTTCCGAGAAGATGACGTCGCAGAGCGCACGAGGACCCAAGAGGCAGCTGAACAATAACATCGCCACGACAAATCACAACGCCTATTTGCCTATTCTTCCGAAATATTCGGaagccgccgccgctgcttTCATCCATAACATGCAGGCCTCCAATCCAGCAATGCAACAATTCTACATGGCTCAGCACGGTCTTCTGAACGGACATCCAATGAATCCGTATTCCATGCCAGCGTTGACCCATCTGCTGGAGAAGCTGCAGGGCTCATCGCCGAGTCACTTATTGCAGGAGGATGTGATCAAGACTGAGGATCAGAAGGAGTCCAATAAATCGAATTCGTCCAGTTGCGGTGATCTCATCATGGACGAAGAAGAAGTGGACACTAAATCGGAAAACAATGATAGCAAATCCGAGATCAACAGTAACAACGATGATTTAGAGGCGGTCAAGAGGATATTGGACACGGTGAATGCGTCCGTAACAAAGCAATTTCTACGTGCGAACATGCAAAAATACTCGGACAACTCGAGCGATTGTCAGAGCGTGCGATCCGTGCATTCGCCCCCTTCGGAACTCTACTGCAACAGCTGCAAGAAGAATTTTGCGGGACAATTGGAGCTCGAGGAGCACGAATGCGAGACTAATGTTGATGTTAAGAGCGAGGGCTTAGCCGCTAAATTGGAGGAGGCTATAGTGCCGAAGACGGAACCGCAGGAGGCGAACGGTGTGGGAAGCGGCAACGAGGAGGAGGACGATAAGCAGCAGCAGGAGTACGACATGGACAGCGAGTCCGTGACGACGACGGATCAACTTACGGAGGATGGGAGAAAGGTGCGAGTTCGGTCGCTGATCTCGGACGAGCAGTTGAAGGTGCTCAAGGACAATTACAATCTGAATCCGCGTCCGAAACGCGAGGAATTGGCGAAGATCGCCGAGCAGATCGGCTTCCAGGTGCGCGTCGTGCAAGTGTGGTTCCAGAACACGAGGGCGCGCGATCGTCGCGAGGGCCGTTTCATCCAGGTGAACTACAACACGCAGACACCGTTGCCAACGCAGCAATCGTCGACGATGATCAATTCGGGTTACCCCCAACCCGTGGTGCCTTCACAAACCCAGCAGTATCCTTCCCACAAAATTTACCCCCAACATTATTCCAGCGAGCAACCGCTGGATCTCTCTACCAAGAAGGAACCGTCGAGGGAGTCGTCGCCGGCGAGCTCGCCGCACCGACCCTCCTCCATACACCATCATTCCGACTCGGGCGAAGAGGTCGTCAATCTCAGTCACAAATCCTCGAGAAGCCCGACACCCTTCCAGCAGCACCATCAGATCCCGTACCAAAGTCATTACCAGGCGTCGAACTGCTCCTCCGAGCCGCGCCGTTCCCCATCGCCCGTCGACTACCATCTCCATCAGAATAACAACAGCAGCCGGCTGGCGCATATCCTCGGACAGCCGTCGCACAAGCTCTCTTTGCCCTACATGCCCATCGAGAGGATCATGCAATACGGCCCGCACGACATGACCTCCTTTGCGCAGCACCTCATCAACAATCGCATCTCCAGCATCAGCCCCAACTTGGACAAACGGTCCTGGTCTGATGCCGCGGCCGCAGCTTCATCCATCGGCGACATGGACTGCGATGAAGATCTGCAGCAGTCGAAGCGCGGAAAACTAGCGGCAAAGGGATTAGGAAGCCCGATGCTCGGCAACCAGGAGGTCGAGATCGAGGGACAATTCACGTGCGACCAATGCGAAAAAGCATTCTCCAAGCAGAGTTCCCTAGCCCGACACAAATACGAGCACTCAGGTCAGCGTCCACACAAATGCGACGAGTGTCCGAAGGCCTTCAAACACAAGCATCACCTCACCGAGCACAAGCGTCTGCACACGGGCGAGAAACCTTTCCAGTGCTGCAAGTGCCTGAAGAAGTTCTCCCACTCCGGCTCCTACAGCCAGCACATGAACCATCGATATTCGTACTGTAAACCCTACAGAGAGTAA
Protein Sequence: MVARSESMFGCYDSYSYRLWSLANVWNTCQLPSLTNGVSKEGEEGEYFIKCPLCQKGCQTLQSLKDHMEAAHPEAYIEPGNLQTTPSAVSPTPSLGGGAGIGGIGPYGCSQCATSFASKDQLEKHELLHSANAQVTCKICSKNFANVYRLQRHMISHDESAVLRKFKCTECEKAFKFKHHLKEHIRIHSGEKPFACGNCGKRFSHSGSYSSHMTSKKCLVMNLKLGRTRAPTTTASGVSEKMTSQSARGPKRQLNNNIATTNHNAYLPILPKYSEAAAAAFIHNMQASNPAMQQFYMAQHGLLNGHPMNPYSMPALTHLLEKLQGSSPSHLLQEDVIKTEDQKESNKSNSSSCGDLIMDEEEVDTKSENNDSKSEINSNNDDLEAVKRILDTVNASVTKQFLRANMQKYSDNSSDCQSVRSVHSPPSELYCNSCKKNFAGQLELEEHECETNVDVKSEGLAAKLEEAIVPKTEPQEANGVGSGNEEEDDKQQQEYDMDSESVTTTDQLTEDGRKVRVRSLISDEQLKVLKDNYNLNPRPKREELAKIAEQIGFQVRVVQVWFQNTRARDRREGRFIQVNYNTQTPLPTQQSSTMINSGYPQPVVPSQTQQYPSHKIYPQHYSSEQPLDLSTKKEPSRESSPASSPHRPSSIHHHSDSGEEVVNLSHKSSRSPTPFQQHHQIPYQSHYQASNCSSEPRRSPSPVDYHLHQNNNSSRLAHILGQPSHKLSLPYMPIERIMQYGPHDMTSFAQHLINNRISSISPNLDKRSWSDAAAAASSIGDMDCDEDLQQSKRGKLAAKGLGSPMLGNQEVEIEGQFTCDQCEKAFSKQSSLARHKYEHSGQRPHKCDECPKAFKHKHHLTEHKRLHTGEKPFQCCKCLKKFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01058305; iTF_01059016; iTF_01059302;
90% Identity: iTF_01058305; iTF_01059016; iTF_01059302;
80% Identity: iTF_01058305;