Ninv007973.2
Basic Information
- Insect
- Nicrophorus investigator
- Gene Symbol
- -
- Assembly
- GCA_963457615.1
- Location
- OY735142.1:1912377-1922124[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 34 0.095 8.7 7.3 0.6 1 21 249 269 249 270 0.94 2 34 0.0081 0.74 10.6 3.7 1 23 276 298 276 298 0.97 3 34 1.1 98 4.0 1.1 1 21 480 500 480 501 0.95 4 34 0.84 76 4.3 0.6 2 23 508 530 508 530 0.92 5 34 0.024 2.2 9.2 1.5 3 23 536 556 535 556 0.97 6 34 0.0094 0.85 10.5 4.1 1 23 562 585 562 585 0.96 7 34 0.067 6.1 7.8 0.3 1 11 590 600 590 602 0.91 8 34 0.00016 0.014 16.0 0.5 2 23 607 628 607 628 0.97 9 34 0.13 12 6.8 0.4 1 23 634 657 634 657 0.93 10 34 8.3e-05 0.0076 16.9 2.1 1 23 662 684 662 685 0.95 11 34 4.1e-06 0.00037 21.0 4.6 1 23 694 716 694 716 0.99 12 34 1.3e-05 0.0012 19.4 0.1 1 23 722 744 722 744 0.98 13 34 0.00095 0.087 13.6 3.2 1 23 750 772 750 772 0.97 14 34 0.00027 0.024 15.3 3.7 1 23 778 801 778 801 0.98 15 34 0.0053 0.48 11.2 1.4 1 20 845 864 845 866 0.94 16 34 0.18 16 6.4 0.2 5 21 966 982 965 983 0.92 17 34 0.00065 0.059 14.1 0.9 2 23 1022 1043 1021 1043 0.95 18 34 0.79 72 4.4 0.4 2 21 1048 1067 1047 1068 0.92 19 34 6.7 6.1e+02 1.5 0.4 2 21 1136 1155 1135 1156 0.90 20 34 0.54 49 4.9 1.2 2 23 1253 1274 1252 1274 0.95 21 34 6.8 6.2e+02 1.5 0.5 1 21 1593 1613 1593 1614 0.86 22 34 0.099 9 7.2 0.3 2 23 1643 1665 1643 1665 0.92 23 34 5.9 5.4e+02 1.6 0.1 3 13 1667 1677 1667 1680 0.87 24 34 0.11 10 7.1 0.2 2 23 1712 1734 1711 1734 0.88 25 34 0.00031 0.028 15.1 4.3 1 23 1922 1944 1922 1944 0.98 26 34 8e-05 0.0073 17.0 2.6 1 23 1950 1972 1950 1972 0.98 27 34 1.9e-05 0.0017 18.9 6.8 1 23 1977 1999 1977 1999 0.99 28 34 0.00014 0.013 16.2 2.1 3 23 2007 2027 2006 2028 0.95 29 34 0.0028 0.25 12.1 1.5 1 23 2033 2055 2033 2055 0.97 30 34 5e-05 0.0046 17.6 1.6 1 23 2065 2087 2065 2087 0.98 31 34 0.00029 0.027 15.2 0.3 1 23 2093 2115 2093 2115 0.98 32 34 0.00025 0.023 15.4 0.5 1 23 2121 2143 2121 2143 0.98 33 34 0.00012 0.011 16.4 3.2 1 21 2149 2169 2149 2171 0.96 34 34 0.0023 0.21 12.4 6.7 5 23 2180 2198 2169 2198 0.89
Sequence Information
- Coding Sequence
- ATGGCTAGCACAGTGGAATTGATGCATTTGTGTAGACTGTGCTTAGTCAAAGAACAAGTAAATGTGCCTATCTTCGAGGATCAGGAACAGGAGAGCcagattttcatgaaaatcgtTACTTGTCTGCCGGTCAAGATAAATAAAGATGATAAATTACCCAAGAAAATATGTGGTGGCTGCTCTTACAAGTTGGACTTGTTCTACCAATTCCGCAATTCTACAACAAATGCAGAGAAACAATTACTACTATGGTTTAACAAAGTTGGATTTGATGGTGCAGATAATGTTGACAGCCCAGCTGAAGTACAGAAGGACATAGTTGATGATGTCCAAGCAGATTCAATTTCAACAGAAACGCAAAGTTATATattgcagcaacagcagcTACCATATGGGCCGGTGGAGTTCTTCCAGGGGGATTTTGATGATTCTCAACCTGCTTCTGGTACTAGTGAAAGTGAAATAATTGAGGAACCTGCAGCAAAGAAACGCAAATGTGCAACAAAGAATGTATTGAATAAGAAGAGTAAAACTGTGGTTACAACTAAGacTGATGCCAGTGATGACGACGATGAAGATGACGATGTTAACGATCCTAATGAGTTGACCTATGATGATTCCAAATTCGCAATTTCTTGTGACCAAGACGTTGAGCAAGCTGGTCCTTCGGGGATTGGAAAAGCTGATACACAATTTGAGGAAGTCATCATTAAAACAGAGCACGGTTCGCCTCTAATAGCAAGCTACCAATGCGAAGTGTGTTCTCAATTATTTCCCGACCGGAAGCAATATTTAGAACACCACATGTCGCAATTCGGATCTACGTTCAGTTGCTGCAGATGCAACGAGGCCTTTAAAAACAGCACGGAATTGTACCAGCACTACAATGAGCACAGGGATGAGGAGGAATTGGATGGAGAGATTATATATTCAACGGAGGCGGAGATGTTGAGGGAGGAGGAGATCAAAGAGGAAACGGTACAAGAAGAAGACTACTCTTCGGAAAATATGGAGGCGGTCATGAATATCCCTGGAGCAGAGGGTATGAGCGATGGCAACGAATTGCTTTACATCATAGATGACAGTAATTGCGTTAACGAAGTCATTATCGAGGAGGCCGACCAGATTGCGATGAATCCGACTAGGGACAACTATACAATCGTGCAGGTTGATCACGGGTACATCATACCGAGCGTATTCAAAGGTCAGTTGCAATCGAAGCGAAAGTACAAGAAGAAAGAGGAGAAGGATGTGATGTACGACGATGAGGACGCCAGAGCTACTGAGGTGCTTGTGAAGATGGAACCATCCACCAGTAAACACAAGCCCACAATCCTGCGAATGCCTCCGGTGCCCAAACGCAGACACGAAGTACCTGACTTTTCCGCAACCAATTATCAGCTCTTGAGTCCAAACGAGGAAGTGGTCGTACCGCATTACAAGTGTTTACGTTGCGAACAATTGTTCATCAACAAGTTCGTCTTTTTCAGGCATATAGAAAAAGGCAAATGCTACGTGAATAGTTGCGATGTCTGCTCGGACACGTTCGAAAAGAATAGCGATTTCTATCAGCACTACGTGAGCACACACAATGAACGAGCGATCTGTAACTTCTGCTTCAGAACGTTTATGTACGAGAAGAACGTGAAGGAGCATATGCTTCGGCATCTGGATCAGTTCAGACATCGATGCGAGGAATGCAATAAGGGTTTCTATACGGTGAGAGAATACCGGAACCATTACAAAAACCGGCACATGGGAATCAGACACAAGTGCAATGAGTGCGGTCGATCTTTCGCCGATGATTGTGGTGAGAATGTGTGCGATGTTTGTGCAAAAGTGTTTTCTGTTCCGTGTATGTTAAGGATTCACATGCGAAGGCATTTTAAAGAGTACACTTTTAACTGTGACAAATGCGATTTTGGAACGTTTCGAAGGGACGTGCTGAGGAGGCATGAAGAGGTCGTGCATAACGGGATGAGGTTCATATGCAAGGTGTGCGGAAAGATGTTCACGAGCAAGTACTCGCAGATCGCTCACGAAAAGATGCATCATCGCCAAATCCTCGACTGCGAGAAGTTCAAGTGCGAGATCTGTAACAAGGTGTTCGTCCACAAAAAGACTTTGGTTCATCACATGAAGATACACAACGGGAATAACAAGTTTGTGTGCGATGTTTGCGGTAAAACTGTGGCCTCTGCCGATAGCCTGAGGCATCACCTGATGGTGCATTCGGGATCGAAACCATACACTTGTCCGGTGTGCGGGAAACGTTTCAACAAGAAGCAACTCTGTACCATTCACGAAAGGACCCACGGAAAGTCGAAGCCGTACAGTTGCACCATATGCCATAACAATTTTACCCAAAGATCGTCCCTCGTCGTTCACACTCGCCGATTTCACACCACTATCAGACCATTTACTTGTGATATCGAGAACATCGACAGGACGAAGTATTCGTTGGTGAAAACGAAAAGGAGAAAACTGGTCTCTCTGAATCATGTTAACATCATAGATAACCCGAGAACGAAGTACAAATGCACGCATTGCAACGAACGATTTCAAGACTACCAAATGCTGCAGTCGCACAAGGAAATATGCATTCAGGAAGATAATGAAGATAGAGATTTGACGGATGATAACGACGATTATGATTATAAGTACTATAAAAGACTGCGATCCTCCACTTCAAATACAGCAAAAACAGCTTCGGCAGCAGCAAAGACTGCCACCATTTCTTCTGGACAAGTCGTTAGCACCACTACTCCAGAAAACACTACCACCACGATTTCAGAAGCCACTAGTGCAGTCTCCACCATCATCACCAATTCCAAAACGAAAGCAACAACTAATAACACGGATGCCGATTCTGATGACAACAAATCATACTTGTGCAAGTGCGGCAAGAATTTTACCAGGACAGGCATGTACATTGCGCACACGATGATGTGCAGGGTATACGCAATGGCAAAGAATACTGATCATTTTCAGTGCAAGCACTGCCACAGGTTTATTTACAGTCTACAGTTTCATAATCACACCTGCGTTCCGGCTCCGAAATGGAACTGTTACGACTGCGATAAGAATTTCAAATCGTTCTATGAGCTGGTTCAGCACTACAAGGACCATAAGCATTCTATGACCTGCGGCACGTGCTTAAAGGAATGCACGAGTTACGGTAGTTTGGCGGCACATAAAATGTCTTGCACTCCCAAATTTGCAACGAAGGTTACAAAGGCTGTAACTTCTACGATAACAACAACTACCGCTTGCATCGCGTCTACCGCTCAATCGTCTTGCAAAACAGCCGAAGCCGAACAGTCAACGCAAATACCTGCCGAAACTAAAACCACCActtcaaacaaaacaaaaataagcaCCACCACCGGAAAAACGAAGAGTAAAACCTGTAAAATTTGTAACGTAATATTACCTTCGgatgaaaaacttaaaatgcATACATGCGTTGCACCGTCTACTGCGGCGACGATGACTACAACCAAATGTGATCTGTGTTCGGTCAGGCTGCCTCCGGAAGATCTCACTAGTCACGTCGAAAGTCATTTTTCTATTGTTCAAGTGAAAAACGTAACTCCCTCAACttctttggaaataaaatcgCGGGAATTGTCTGCGGAGCCAAAAGCACCGTTGAATAATAATGGAGAGGCGGAGAGTTGTCGGCTGTTATCGGAATTAGATAATCTGATTATGTCTGACACGAAGAACCAAAAGGTAACTTCCACGAAGTCGTGGAAGTGTacgatttgtaataaaattgagacCACGGAGCAAAAGTTGAACGAACACTTGGAACACCATATAACTGTGCACCAAAAGCCCAACAACGGATTTGCCGAAAGCAACCCTCTTCCTGCAAAACCGCCGACGACAACCACTATGAAGTATAAAGTGAAAACTGTGGGAGTATTACCTAAAACCGTAGATGTATCAAAGATCACAAATCAGATGCCAAGACAAAGGGTGGTCCCACTGATAAACAACCAAAATCAACCGAAATTATTCTTGATAATGACGCCCACTGGTGGGACGTCCAGTGTGACTCCTGTATACACAACCATGACGAATCTTAATCTGATGACACAGAGTTTGAGCACCTTCGCTATACAACCTCAACTTAATTTGAACACCATTCCAACAACCGCCCAGATTCCGGTAAGAATGCAGATCACGCCATCAAACATGCAACAACCGACAGGCAATGGTATTAGTAATTTTGTGATAAGCGAGGTCACGTCTGGACCTGCTGCACAGTCCATGATAGAACAGCAATCGCCGGCAAATGCAGTTCAACCCGCCGAAAGTGGAGTTTCATCGGCAGATCCAACTActgtaactaataatattgatgatgATTCCTCCGCTAATAATATTGGTGAAGCGATCGATGATGGATTGGTAGAAAATGCTATTGATGATAGTAATCCAAACtataaaccaaaaatatttgtaaagccCCTAAGTCAGTTATTAAAAAGCCCCATTAAAACGATCGTCAATGAAGCTGTTAACACAGAGAGTCAAAAGCAAAATAGTGATGTTAGTCCAGTGGAAAATATAACGGATACAAATGCGAGTATTGTGATCAATCAAATTGTTGCTGAAGCCAAAGGAACTCCAACGAACTTGGTGTTAGCCGAACCTCGCACAGTAGAGGCACAGCCTGTTGTTAAGACTATTATTGAAGTGGTTAAACCTAGCACGAGTATACTGCCGAATATTAGTCTAGTGCAAACCAAGGGTGTGAAAAAGTTCTTCAGATGTTCCATCTGCAACATTCTTCAAAGAAAGTCGGTAAGGCTGGAGCAACATCAGAGGAAGTACATGTGCAGAGAGTGTCCTTACTATTGTTGCAAGCTGGTTTTAATGGATAAGCATTATATAGACGTGCACAAATACAAGAACCGGTGCCCGCTGTGCGATAAGCAATTTCCGACTGGAAAAGACCAGATATTGCACAAGAGGGAAGTGCATTGGTGTTCTCAGTGCGGTCGAGGTTTTGCGGATCTAGCGCAGCACGCCAAGGCTTTCAAATGCAAGTCCTGCGAATTTGAGGcatgcaacaacaacatcctGGATAAGCACTACAAGAAGACGCATTGTGTGATGATGCGCTGCACCCCCTGCAACGAGGTGTTCTACTCGCAGGAAAACTTTGCCACTCACAAGGAAgcaatacatttttgcaaaaagTGCAAAACCTACAAAATGGATCTGAACATCCATCAGACATTCTGCAAGGGCATCCCTTCCAGCACCACATCGCCTGTACTCAATACCCCTCAAGTGACTATGAACAGCCCCAAAGGCAATAAAGATACTCGCACCGATTTTGCCTTTTTTAGAAACAATTTCCAAGAAGCCATGTATAGCCAAGCGAACTTTGGCTTGGAAAGCTGCGACTTGCAGGACAGGCAGCAGTACATGCTATGCGTGAAGCAGGAGGGAGAGTACAATCTGCTGGACAGCGCCGTCGACCAGCTAAGCGATCCGGACCTCCTGAACCTCTTGGCCACCGAAGACTGTACGTCCATCCTGCAAAACATAGAAAGCAATGAGAACTTTGAGAGACTAATTAGCAACGATGTGGACGATGCAAATTTGAACTTTCTGGATGCGAACTATTGCGAAAACATCTTGAAAGAGGAATGCTATTTACAGCAGCAGGAGCAACAATTCGAAGAGTCTAAACAGCACGGCGAGAAGAAGATTGTcgatgagagagagagaccgACCGGAGAATTTAAATGTGCTCAATGCGACAAAGTTTGCAGCACTAAAAAGTTGCTCAGGTATCATCTGACCACGCACTCGGATGTTAGACCGTACGCTTGCGAGGTCTGCAACAAGAGGTTCAAGCAGAGGCACGAAGTGAACGCGCACAAGCGCAGCCACAGCAATCCGTCTTTCCAGTGCGATATCTGTTCGAAGATGTTCGTGCACAAATCGCATCTCACCAGTCACAGGAAGAAACACTTGTGCGATTTTTCAGAGTTTTGCAAGGATTGCAATAAGGGTTTCGTATCGAAATCGGCATACTTGAAGCACGTAAAGGTGCACCACGAGAAGGTTTCGCATATTTGCGACATCTGCGGACATCGCCTGAGCACGATAAGCGCACTCAACGAGCACAAGAACACGCACGATCCCAATTATGGAAAGGAGAGGTCGCATGTTTGCGACATATGCGGAAAAAGCTACTTAACCGCGCGCAATCTTAAGACCCACTTAAAAACTCATCTTCAGCTCAGCTCGTACGTCTGCAATATCTGCGGAAAATCATTAAGCAGCAAAAAGATTCTCGAGACACACGTGAAGATGCACATCGGCGAGAAGGATTTTGTCTGCGAATTTTGCAGTAAAAGCTTTGCGGCCAAGGAATATCTGGTGAGCCACAGGAGGATTCATACCGGGGACAAACCGTTCAAGTGTCATCTTTGCGAGAAAGCATTTACCCAAAGAACTACTCTCACCGTGCATCTGCGATGTCACACAGGTGAAAGACCATACAAGTGCCATTGTGGAAAGGCTTTCATCACGAAGAACCATCTGACAAACCATTATAAAACACACGATCTGCCCAGTTTGGATTTCTCATACGAATTCGCGGAGCAAAAgataacatga
- Protein Sequence
- MASTVELMHLCRLCLVKEQVNVPIFEDQEQESQIFMKIVTCLPVKINKDDKLPKKICGGCSYKLDLFYQFRNSTTNAEKQLLLWFNKVGFDGADNVDSPAEVQKDIVDDVQADSISTETQSYILQQQQLPYGPVEFFQGDFDDSQPASGTSESEIIEEPAAKKRKCATKNVLNKKSKTVVTTKTDASDDDDEDDDVNDPNELTYDDSKFAISCDQDVEQAGPSGIGKADTQFEEVIIKTEHGSPLIASYQCEVCSQLFPDRKQYLEHHMSQFGSTFSCCRCNEAFKNSTELYQHYNEHRDEEELDGEIIYSTEAEMLREEEIKEETVQEEDYSSENMEAVMNIPGAEGMSDGNELLYIIDDSNCVNEVIIEEADQIAMNPTRDNYTIVQVDHGYIIPSVFKGQLQSKRKYKKKEEKDVMYDDEDARATEVLVKMEPSTSKHKPTILRMPPVPKRRHEVPDFSATNYQLLSPNEEVVVPHYKCLRCEQLFINKFVFFRHIEKGKCYVNSCDVCSDTFEKNSDFYQHYVSTHNERAICNFCFRTFMYEKNVKEHMLRHLDQFRHRCEECNKGFYTVREYRNHYKNRHMGIRHKCNECGRSFADDCGENVCDVCAKVFSVPCMLRIHMRRHFKEYTFNCDKCDFGTFRRDVLRRHEEVVHNGMRFICKVCGKMFTSKYSQIAHEKMHHRQILDCEKFKCEICNKVFVHKKTLVHHMKIHNGNNKFVCDVCGKTVASADSLRHHLMVHSGSKPYTCPVCGKRFNKKQLCTIHERTHGKSKPYSCTICHNNFTQRSSLVVHTRRFHTTIRPFTCDIENIDRTKYSLVKTKRRKLVSLNHVNIIDNPRTKYKCTHCNERFQDYQMLQSHKEICIQEDNEDRDLTDDNDDYDYKYYKRLRSSTSNTAKTASAAAKTATISSGQVVSTTTPENTTTTISEATSAVSTIITNSKTKATTNNTDADSDDNKSYLCKCGKNFTRTGMYIAHTMMCRVYAMAKNTDHFQCKHCHRFIYSLQFHNHTCVPAPKWNCYDCDKNFKSFYELVQHYKDHKHSMTCGTCLKECTSYGSLAAHKMSCTPKFATKVTKAVTSTITTTTACIASTAQSSCKTAEAEQSTQIPAETKTTTSNKTKISTTTGKTKSKTCKICNVILPSDEKLKMHTCVAPSTAATMTTTKCDLCSVRLPPEDLTSHVESHFSIVQVKNVTPSTSLEIKSRELSAEPKAPLNNNGEAESCRLLSELDNLIMSDTKNQKVTSTKSWKCTICNKIETTEQKLNEHLEHHITVHQKPNNGFAESNPLPAKPPTTTTMKYKVKTVGVLPKTVDVSKITNQMPRQRVVPLINNQNQPKLFLIMTPTGGTSSVTPVYTTMTNLNLMTQSLSTFAIQPQLNLNTIPTTAQIPVRMQITPSNMQQPTGNGISNFVISEVTSGPAAQSMIEQQSPANAVQPAESGVSSADPTTVTNNIDDDSSANNIGEAIDDGLVENAIDDSNPNYKPKIFVKPLSQLLKSPIKTIVNEAVNTESQKQNSDVSPVENITDTNASIVINQIVAEAKGTPTNLVLAEPRTVEAQPVVKTIIEVVKPSTSILPNISLVQTKGVKKFFRCSICNILQRKSVRLEQHQRKYMCRECPYYCCKLVLMDKHYIDVHKYKNRCPLCDKQFPTGKDQILHKREVHWCSQCGRGFADLAQHAKAFKCKSCEFEACNNNILDKHYKKTHCVMMRCTPCNEVFYSQENFATHKEAIHFCKKCKTYKMDLNIHQTFCKGIPSSTTSPVLNTPQVTMNSPKGNKDTRTDFAFFRNNFQEAMYSQANFGLESCDLQDRQQYMLCVKQEGEYNLLDSAVDQLSDPDLLNLLATEDCTSILQNIESNENFERLISNDVDDANLNFLDANYCENILKEECYLQQQEQQFEESKQHGEKKIVDERERPTGEFKCAQCDKVCSTKKLLRYHLTTHSDVRPYACEVCNKRFKQRHEVNAHKRSHSNPSFQCDICSKMFVHKSHLTSHRKKHLCDFSEFCKDCNKGFVSKSAYLKHVKVHHEKVSHICDICGHRLSTISALNEHKNTHDPNYGKERSHVCDICGKSYLTARNLKTHLKTHLQLSSYVCNICGKSLSSKKILETHVKMHIGEKDFVCEFCSKSFAAKEYLVSHRRIHTGDKPFKCHLCEKAFTQRTTLTVHLRCHTGERPYKCHCGKAFITKNHLTNHYKTHDLPSLDFSYEFAEQKIT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -