Basic Information

Insect: Neria commutata
Gene Symbol: ZEB2
Assembly: GCA_963457695.1
Location: OY735247.1:37146322-37152139[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0042 0.38 11.7 1.0 1 23 131 153 131 153 0.98

2 15 0.068 6.2 7.9 2.8 1 23 159 182 159 182 0.97

3 15 0.00013 0.012 16.4 0.8 3 23 369 389 368 389 0.98

4 15 1.8 1.6e+02 3.5 2.4 1 23 395 418 395 418 0.93

5 15 0.12 11 7.2 0.8 1 23 471 494 471 494 0.96

6 15 2.5 2.3e+02 3.0 7.1 2 23 544 565 543 565 0.95

7 15 0.015 1.4 10.0 4.0 5 23 680 698 677 698 0.93

8 15 0.22 20 6.3 0.6 1 23 704 727 704 727 0.95

9 15 0.41 38 5.5 0.2 2 23 764 786 763 786 0.95

10 15 0.021 1.9 9.5 1.6 1 23 800 823 800 823 0.96

11 15 0.0053 0.49 11.4 6.2 1 23 947 969 947 969 0.98

12 15 1.1e-05 0.001 19.9 0.5 1 23 974 996 974 996 0.97

13 15 0.00018 0.017 16.0 5.8 1 23 1002 1025 1002 1025 0.95

14 15 0.0085 0.78 10.8 0.1 3 19 1032 1050 1031 1051 0.90

15 15 0.00054 0.05 14.5 1.2 1 19 1060 1078 1060 1083 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0042	0.38	11.7	1.0	1	23	131	153	131	153	0.98
2	15	0.068	6.2	7.9	2.8	1	23	159	182	159	182	0.97
3	15	0.00013	0.012	16.4	0.8	3	23	369	389	368	389	0.98
4	15	1.8	1.6e+02	3.5	2.4	1	23	395	418	395	418	0.93
5	15	0.12	11	7.2	0.8	1	23	471	494	471	494	0.96
6	15	2.5	2.3e+02	3.0	7.1	2	23	544	565	543	565	0.95
7	15	0.015	1.4	10.0	4.0	5	23	680	698	677	698	0.93
8	15	0.22	20	6.3	0.6	1	23	704	727	704	727	0.95
9	15	0.41	38	5.5	0.2	2	23	764	786	763	786	0.95
10	15	0.021	1.9	9.5	1.6	1	23	800	823	800	823	0.96
11	15	0.0053	0.49	11.4	6.2	1	23	947	969	947	969	0.98
12	15	1.1e-05	0.001	19.9	0.5	1	23	974	996	974	996	0.97
13	15	0.00018	0.017	16.0	5.8	1	23	1002	1025	1002	1025	0.95
14	15	0.0085	0.78	10.8	0.1	3	19	1032	1050	1031	1051	0.90
15	15	0.00054	0.05	14.5	1.2	1	19	1060	1078	1060	1083	0.96

Sequence Information

Coding Sequence: ATGGAGTTAGATTACAGATTGACATGTCGGACATGTCTGGCGTCTGAGGCGGAATTTTACAAGTTAGATGCGCCTATTGCCGATGACGCTGAGGATAATGATAAGGTGCAAAAGATCAGCTTTATGGAGTGCCTCCGCTATTGCACGCGCTTGCCAGATGTACCCGAGCTCCccatctacatatgtacagaGTGCAGCAGTGCGTTGCAAGTAGCGTACAACTTTGTGCGGAACGCCTTGCAGGCGCATGAGGTATTATGCCAGAAGTTGTGTCCGAGCGCGCAAACACATTGCTACGATTCAACGCCCAATCGATTAACGCATATCGGAAAGTGGTCCGGTGTAGGGGAGGAGTCGTGTAGTACTGGCACGCAGGAGAAGGCAATGCGTTTTCGATGTAAAGTTTGTAGCGAAAAGGTGGAATCGAGGAAGTCATTAAAGGAACATGTAAAACTGCATTTGGATATCATTTCCTACAGCTGTCAAATGTGCGCTTACGAAAGCAAGAAGCGTAGTCATCTCAGTGAACACTACCAGAGAATTCATGACCGGCAAGCCAGCCGTGAACTGTTAAAACCAAAAACAGTTGTGCCACAAAAAACATCTCAAACAAACATGAAAGAGGAACTCGAAGATTGGCAAGCGGATGATATTTCGCTTCAAATGGAAGCATTGCACAATGCGCCAAAAGttgaaatacaacaacatcatCTTGAAGTGGGTGCCGTGCTGTCAGCTCATACCAACACAATTAATGAATTCTCCTCAGAATTTCCGATTATGCCACATGAATTGTCGAAGGAAATGTGCATTGGCAATGAGTTTATTGTAATGGCAGATGGCACAGTGGAGGAAGTAATGGGAAATGGTGTTGTAATTGAGTATATTAATGCAGTAGACGAGGATGGGGTATCCCTGGAGCAAAATGGTTTAGTGTTGAACGACGTGGACAGCATGGATGTGGATGACTTGATAATCGAGGAAAATGTTGCTACAGGATTCGTGGAAGAGTCTTCACATGTGCCAGATTTGCCAATGTCAGCGTCAATACCACTCAAGCACTTACCGTCAATAACAAACGCCAGGAAAGATAAAAAGGCGATCTGCAAAATATGCGCGAATAATTTCAACACACAAGATCAACTTAAAACCCACATGCTGACGCATAATGaaattccTCATTTCTTTTGTGATCGTTGCCcgttttatacatttttcaaagtaGACCTAATGCAGCACTACAAAATGCAGCATAATCTGGAGCCTACGTATAAACAGTTGCAGCCGAAGAATAAAGTCAGTTCATATGGCGCCAGCAGCAGTAGCTACAGCAAGGCAAGGAGTGGAGCAGGCCGCCCAATAAAAAGAGGAGGGGGAGGAGGAGGAGAAGCCGTATACAAGCGGTACATTTACAATTGTGATTTGTGTCTATATGAAACAAACGCGAAAGTTAATTTGCGTCGACACTACCTAAGCAAACACCAGCAGAATGCCACAGACGTGCAATTGCGACCTACTATTGAGGAAATAGAAAGATCTGAGGAGCACTGTCCCAGCACGGACAACGTGAGAAACATCGATAACCTACGCAATGTAAACTGCACAAAGCCGGATTATCCCAATGGCTTGCATTGTCGAAGATGCAAAAAAACGTTCCATTGGCGCAGCAAATTGAAAGAACACTACAGATGGCACAAACTCGTGGATACTAACGCGGAAGTTGATGGGATTTCCCCAGCAGAGTATGTCGCTGGCAATACAGCGTTTGATGACAACACGCTGACTGCTCCGCCGACAGCAAATGCATACGCAGTACCTCCCGATGCCATGCCGCAAGTGGTGGAAATCGATGATATCATCGATGACACCGAAATAGATTTTGATTTCAATCAGGATGCGCTCTTCGATGATTTCGATGAAGAGAATGAGGACAATGAGGACTTGCAAGACCTACTACTGACTAGTGATGATGATTTCGAGGACTTACTGGAGGAACAAAGTGAAAATGCTGAGTCGGAAACGCATCCCTTCTGCATACACTGCAATAAGAAGTTCTTTAGCCAGTATCAATTCGAGAATCACATGTTTGTGCACAGAGGCTTGGCACCCTATCGTTGTGAGATGTGCACAAACTTATACAATACCAAGCGTGCAATTATAAGGCATTACAAAGCCGTACACAAACGTATACCCACCAGGGATATGATACAAGCTAAGGGTGATAAGGTGGCCGTGGATAAAACGCCAGTGGAGCATTTGAATCTGGGGGAACAGAAGCCCACCACTCTGATGTGCGCCAAATGTCCTTATGAATCCACGGAGCTGAATAACATACAAATTCATCTGAAAACGAGTCATGGCATACAGAATGAAAACTTCATACTTCAAAAACTGCCATTCGAGTGTCCCCGCTGCATTCGTTCGTATGAGACAAAAGAGTGCCTCGTACGCCATTTAGAACGCAGCCATTCAGTGGCAACCATCATACAGCAAAGGCAGTCTCCGCCTGTGGACAGAAGTTTCACAGAAAacactgccgctgctgctgctgcgactaTAAACGCAGCCCCTGCCGCAAGTTGTGgcGAGACAATAGCAGAGCTAAGTCAAAACTCCAGccctagcaacaacaacaatgacaatacACCCACGACATTATACACTACAGCGCAATTGGCACCAGTAGCGGAAATCGATTTAGCCGTAATTACCATTAGCGACGAGGCAAGTCTGCCCCGATATCAATGCGTTGCCTGCGAATTTTATTGCCAAACGCTCGTCGATCTGGACGAGCACAGCAAGCGGCATCCGAGGGATGGCACACGCGACACGCTCAATTTTATGTGCCCCATCTGCAAGTGCAAGTACAAGTCGCTGATGCTGCTGAAGCACCACTTGAAGCGGCACACGGGCCGCACGTACGCATGCGCTGACTGCCCGAAAACGTTCGTAAATCGCAGAGAGCTGGAGCATCATCGATTGATACACACAGGCGAGATGCCGTACAAGTGTGAAGCATGCGACAAAAAGTTCCGCTACTCGCATCACCTGAAGCGGCACACGGACGTGCAGCATCTGGGCAAGCGGCAGCTTTGTACAGTGCCCGGCTGCGGGCGGAAATTCACGACGTTGGCACAACTGAAGATACACAGCTGGAATCACAATGGCATCGTTCCGTACAGGTGCAAGTACTGCGAGCGAGAATTCAAGAAGCGGGAATTACTGCGGCAGCATGCCTGGAAAGTGCACCAGGTCACGCTCACCGAGGAGGAAATCGCAGAAATTTATCGCAAAACCGTTGGCTATACGAATCCGTACGACTTCACTGTGCCTGTCTCGAGTGGAATAATGTTGCGGCGTTCCGACGCGGAGGAGTTTGAAAAGTCGCCACCCAAAAGCGGGGAAACTGAAACGTTGTAA
Protein Sequence: MELDYRLTCRTCLASEAEFYKLDAPIADDAEDNDKVQKISFMECLRYCTRLPDVPELPIYICTECSSALQVAYNFVRNALQAHEVLCQKLCPSAQTHCYDSTPNRLTHIGKWSGVGEESCSTGTQEKAMRFRCKVCSEKVESRKSLKEHVKLHLDIISYSCQMCAYESKKRSHLSEHYQRIHDRQASRELLKPKTVVPQKTSQTNMKEELEDWQADDISLQMEALHNAPKVEIQQHHLEVGAVLSAHTNTINEFSSEFPIMPHELSKEMCIGNEFIVMADGTVEEVMGNGVVIEYINAVDEDGVSLEQNGLVLNDVDSMDVDDLIIEENVATGFVEESSHVPDLPMSASIPLKHLPSITNARKDKKAICKICANNFNTQDQLKTHMLTHNEIPHFFCDRCPFYTFFKVDLMQHYKMQHNLEPTYKQLQPKNKVSSYGASSSSYSKARSGAGRPIKRGGGGGGEAVYKRYIYNCDLCLYETNAKVNLRRHYLSKHQQNATDVQLRPTIEEIERSEEHCPSTDNVRNIDNLRNVNCTKPDYPNGLHCRRCKKTFHWRSKLKEHYRWHKLVDTNAEVDGISPAEYVAGNTAFDDNTLTAPPTANAYAVPPDAMPQVVEIDDIIDDTEIDFDFNQDALFDDFDEENEDNEDLQDLLLTSDDDFEDLLEEQSENAESETHPFCIHCNKKFFSQYQFENHMFVHRGLAPYRCEMCTNLYNTKRAIIRHYKAVHKRIPTRDMIQAKGDKVAVDKTPVEHLNLGEQKPTTLMCAKCPYESTELNNIQIHLKTSHGIQNENFILQKLPFECPRCIRSYETKECLVRHLERSHSVATIIQQRQSPPVDRSFTENTAAAAAATINAAPAASCGETIAELSQNSSPSNNNNDNTPTTLYTTAQLAPVAEIDLAVITISDEASLPRYQCVACEFYCQTLVDLDEHSKRHPRDGTRDTLNFMCPICKCKYKSLMLLKHHLKRHTGRTYACADCPKTFVNRRELEHHRLIHTGEMPYKCEACDKKFRYSHHLKRHTDVQHLGKRQLCTVPGCGRKFTTLAQLKIHSWNHNGIVPYRCKYCEREFKKRELLRQHAWKVHQVTLTEEEIAEIYRKTVGYTNPYDFTVPVSSGIMLRRSDAEEFEKSPPKSGETETL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -