Basic Information

Insect: Nephrotoma guestfalica
Gene Symbol: Zfa
Assembly: GCA_963691935.1
Location: OY829914.1:235504989-235514028[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 7.1e-05 0.014 17.6 3.7 1 23 42 64 42 64 0.98

2 8 0.0012 0.24 13.8 0.5 1 23 88 111 88 111 0.97

3 8 0.018 3.6 10.0 8.8 1 23 117 140 117 142 0.93

4 8 0.00069 0.14 14.5 0.8 2 23 167 189 167 189 0.91

5 8 2.9e-06 0.00058 22.0 2.2 2 23 205 227 204 227 0.97

6 8 0.082 16 8.0 3.5 2 16 234 248 233 258 0.85

7 8 4.9e-06 0.00096 21.3 5.7 1 23 264 286 264 286 0.99

8 8 9.5e-07 0.00019 23.5 1.6 1 21 292 312 292 313 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	7.1e-05	0.014	17.6	3.7	1	23	42	64	42	64	0.98
2	8	0.0012	0.24	13.8	0.5	1	23	88	111	88	111	0.97
3	8	0.018	3.6	10.0	8.8	1	23	117	140	117	142	0.93
4	8	0.00069	0.14	14.5	0.8	2	23	167	189	167	189	0.91
5	8	2.9e-06	0.00058	22.0	2.2	2	23	205	227	204	227	0.97
6	8	0.082	16	8.0	3.5	2	16	234	248	233	258	0.85
7	8	4.9e-06	0.00096	21.3	5.7	1	23	264	286	264	286	0.99
8	8	9.5e-07	0.00019	23.5	1.6	1	21	292	312	292	313	0.95

Sequence Information

Coding Sequence: ATGGAACCAGTAGAAGATGTAGGAATTGAATATGCTGAATATATGATCGAAGAGATTGTCGAAACAGAAGAATTTGTCGAAGAGGAATTTATTGTGtgtgaagaaattgaaaatcagATTCAGTATCAATGTGATATATGCCAGCGTTTATTTGATAAACACTACTATTTGGAACGTCATATGCAATACCATAATGTTGAAGAAATTgatgatgataataattttgaagaagAAGaCCTTCAAGAAGACGACATTCAAACGTACGACTGTGACACGTGTAAAGAAAAATTCTACGATGTTGAATCATTGAACGAGCACAACAAAACCGTACATAAACGGAATCGCATTTATAAATGTTCAGTATGCACTAAAATCTATCGTACACGGCATAGCCTCTACAAACATTTTCATCAGTGTCACACGGAATCGGATCGTTGTATCGCTTGCGATGAAACCTTCACTGATATCATTGAACACGTAAAACAGCATCATGGCGAAAAGTGTCCCGTATGCgagaaacattttttcaatctcGACGAATTACACGATCATATTGTGGCGATTCATGTGGCCAAAATTAAACCTGAAAAAGCGGATGAATTGCCCGAATTACAATGTAATATATGTTCaaagcaatttaaaaatgtaatacatTTGCAGGCCCATATGCGGCGTACACATTCAAAAGAGAAAATTTTAGAGTGTCCGCTATGcggtaaacaatttaaaagtgcAAACAGTTTTACATGCTATACGAGtcatataaatatacatacgGGTGAGAAACCGTACAAGTGTCAATATTGTTCGAAAACGTTTAGTAATTCGGGCACATTGCAtaagcataaaaaaatccataccggtgaaaattttcatcgatGCAGTTTGTGTGATAAAAAATTCCGTGATGCTAGCTATTTAACCCGTCACATAAAAAGTTGTTCGTATCGATATAGTGGATAA
Protein Sequence: MEPVEDVGIEYAEYMIEEIVETEEFVEEEFIVCEEIENQIQYQCDICQRLFDKHYYLERHMQYHNVEEIDDDNNFEEEDLQEDDIQTYDCDTCKEKFYDVESLNEHNKTVHKRNRIYKCSVCTKIYRTRHSLYKHFHQCHTESDRCIACDETFTDIIEHVKQHHGEKCPVCEKHFFNLDELHDHIVAIHVAKIKPEKADELPELQCNICSKQFKNVIHLQAHMRRTHSKEKILECPLCGKQFKSANSFTCYTSHINIHTGEKPYKCQYCSKTFSNSGTLHKHKKIHTGENFHRCSLCDKKFRDASYLTRHIKSCSYRYSG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01053818;
90% Identity: iTF_01052660;
80% Identity: -