Basic Information

Insect: Nephrotoma guestfalica
Gene Symbol: -
Assembly: GCA_963691935.1
Location: OY829915.1:59589494-59591570[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 2.6e-06 0.00052 22.1 4.5 1 23 269 291 269 291 0.97

2 12 9.2e-08 1.8e-05 26.7 0.6 1 23 297 319 297 319 0.99

3 12 0.00011 0.022 17.0 1.4 1 23 325 347 325 347 0.99

4 12 8.1e-07 0.00016 23.7 0.6 1 23 353 376 353 376 0.97

5 12 1.9e-05 0.0038 19.4 0.7 2 23 385 406 384 406 0.97

6 12 1.5e-06 0.00029 22.9 1.2 1 23 415 437 415 437 0.98

7 12 6.1e-06 0.0012 21.0 2.0 1 23 443 465 443 465 0.98

8 12 5e-05 0.0099 18.1 2.0 1 23 471 493 471 493 0.99

9 12 3.3e-05 0.0064 18.7 4.3 1 23 501 523 501 523 0.98

10 12 0.00064 0.13 14.6 0.6 1 23 531 554 531 554 0.91

11 12 0.0058 1.1 11.6 0.1 1 23 558 581 558 581 0.93

12 12 0.0029 0.56 12.6 2.1 3 23 588 608 586 608 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	2.6e-06	0.00052	22.1	4.5	1	23	269	291	269	291	0.97
2	12	9.2e-08	1.8e-05	26.7	0.6	1	23	297	319	297	319	0.99
3	12	0.00011	0.022	17.0	1.4	1	23	325	347	325	347	0.99
4	12	8.1e-07	0.00016	23.7	0.6	1	23	353	376	353	376	0.97
5	12	1.9e-05	0.0038	19.4	0.7	2	23	385	406	384	406	0.97
6	12	1.5e-06	0.00029	22.9	1.2	1	23	415	437	415	437	0.98
7	12	6.1e-06	0.0012	21.0	2.0	1	23	443	465	443	465	0.98
8	12	5e-05	0.0099	18.1	2.0	1	23	471	493	471	493	0.99
9	12	3.3e-05	0.0064	18.7	4.3	1	23	501	523	501	523	0.98
10	12	0.00064	0.13	14.6	0.6	1	23	531	554	531	554	0.91
11	12	0.0058	1.1	11.6	0.1	1	23	558	581	558	581	0.93
12	12	0.0029	0.56	12.6	2.1	3	23	588	608	586	608	0.96

Sequence Information

Coding Sequence: ATGAGCATTCGAATCGATATAAATGTGTGCAGAGTATGTATGAAAACGGGAGACGGACAACCAATCTATGCGGATAGCgaaacagcaaaaaaatttcaattttgtacacaattagagATTTCAGAAAATGATGATTTACCAAAAACGTTGTGCAATAAATGTGTTGGACGGTTGAAAATTGCTCATGATTTTCGTAAACAAGCCGAGGCAACAGATAAGCACCTAAAGCAGGTCATTTCACATTTCACCGAACAACTTAACCAGTCAGTGCAGGTAAAAGAGTGTCTAGACGATGAATTGGACGCCGAAATTGATGATATGCTGGTGGATACACATAATTATGTGGATGAGGAGGAGCTGCCTCTAACAAAAATTAAGGTCAATCAAGATGATCACATTGAGCAGCTCACCGATCATGATCATCATGAAGATCACGATGAATCGGAACAGATCCCGATGATGAATATTTCTCATACTCAGAATGAAATTTCGATAGAAGCAGAAAATATAGTATATGAAGAAATAGAAAGAGAATGTGAAGGTGCTCCCGTGTACATCGAAGTAGAAGAGTGTGGTGATATTACGAGCGAGGCGCACCTTGAAGAAGTGGAAGAGATTGAAGAAGGAGGAGGTGTGGAAGATTTAGAAATGGAAGAGAGAAAACCAGtaaatttattcacaattaCTGAAGTTAACTATATGACTGAAAATGAGGGTGAAGGTGAACAAACCGATCCGGGTACTGGAAACGAAAGTGATTCGAAAAAGGAAGTTGAATCATTCCTTATGTTTTCAGGAAAAACTCATAACTGcagtaaatgtaataaagatttCAGTACCAAAACCAATTTGATACGCCATTTGCAAACTCATGATGGTGTTAAACCATACGAGTGCAGCATATGTGGTACCCGTTTCACCCAGAACGGTTCACTTAAACAACATTTACGAATACATTCGGGTGAGCGACCTTACAAATGTAATGTTTGTGGCCGAGGCTTTACCCAGGGAAAATCGTTGTCATTCCATATGAGAAGGCACACGGGTGAAAAACCGTACACTTGCGAAACGTGCGGGCTATCATTTCGGCAAAAGGACGGTTTAAAGCGACACGTTATGATTAAGCACAGCGATATTGAGGTGGAAGGCCAACCATGCCCGACATGCGGCAAAGTTCTCTTTTCCAAGTACACGCTTCAAATGCACATGAAAAAACATTTGGGCACTCAACCAGAAGACACGCACAAGTGTGAAAAATGTGATCGAGCATTTTCGTCTAAGGCATCACTAATAAATCACGTACGATGGCACACTGGAGAAAAACCCTTTAAATGTGAAACATGCAATAAACAGTTCTCTCAGAAAGGGTCGTTGGTGTCCCACTTAAAGCAGCATCTAGACGTTAAGCCCTATAAATGCGAAACGTGTAGCAAAGGATTTACCCAAAAGCACCAAATTGTGGCACATCTAAATATGCATcagaatcaaaatttaaaaaagttcaaATGTTCAAAGTGTCATAAAAGTTTTGCAATCAAGCGAAATCTTATCCAGCATCTTAAAAATCACGAACGAGACGATTGCGAGGAGTTTAAATGCGAAGATTGCAATATTGGATTTAACTCGAGGCGTGGTCTCAAATTACATCGTGGCAATCAACACAAAGACGATCATATGTGCGAAGTATGTAATGCCCAGTTTGTGATGGCCACCGATTTAAATCAGCACATCGAATTGATACACGATGATATTGATATGAATTGCGAGATGTGTGATCAGCAATTTTTCTCACACAAGTTGTTAACGAGTCATATGTTGGAACATGAGCTGAGTGAAATtgcataa
Protein Sequence: MSIRIDINVCRVCMKTGDGQPIYADSETAKKFQFCTQLEISENDDLPKTLCNKCVGRLKIAHDFRKQAEATDKHLKQVISHFTEQLNQSVQVKECLDDELDAEIDDMLVDTHNYVDEEELPLTKIKVNQDDHIEQLTDHDHHEDHDESEQIPMMNISHTQNEISIEAENIVYEEIERECEGAPVYIEVEECGDITSEAHLEEVEEIEEGGGVEDLEMEERKPVNLFTITEVNYMTENEGEGEQTDPGTGNESDSKKEVESFLMFSGKTHNCSKCNKDFSTKTNLIRHLQTHDGVKPYECSICGTRFTQNGSLKQHLRIHSGERPYKCNVCGRGFTQGKSLSFHMRRHTGEKPYTCETCGLSFRQKDGLKRHVMIKHSDIEVEGQPCPTCGKVLFSKYTLQMHMKKHLGTQPEDTHKCEKCDRAFSSKASLINHVRWHTGEKPFKCETCNKQFSQKGSLVSHLKQHLDVKPYKCETCSKGFTQKHQIVAHLNMHQNQNLKKFKCSKCHKSFAIKRNLIQHLKNHERDDCEEFKCEDCNIGFNSRRGLKLHRGNQHKDDHMCEVCNAQFVMATDLNQHIELIHDDIDMNCEMCDQQFFSHKLLTSHMLEHELSEIA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01052494;
90% Identity: iTF_01053666; iTF_01052494;
80% Identity: -