Basic Information

Insect: Nephrotoma guestfalica
Gene Symbol: -
Assembly: GCA_963691935.1
Location: OY829914.1:11236255-11238077[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 3e-05 0.0059 18.8 1.3 2 23 216 237 215 237 0.96

2 12 0.00013 0.026 16.8 0.7 1 23 244 266 244 266 0.97

3 12 2.4e-08 4.8e-06 28.5 0.4 1 23 282 304 282 304 0.99

4 12 4.2e-05 0.0082 18.4 1.3 1 23 315 337 315 337 0.98

5 12 0.00029 0.056 15.7 0.5 2 23 344 365 343 365 0.97

6 12 0.16 31 7.1 2.4 1 23 371 393 371 393 0.95

7 12 0.00027 0.053 15.8 3.0 3 23 403 423 402 423 0.98

8 12 3.5e-05 0.0068 18.6 1.3 1 23 429 451 429 451 0.98

9 12 7.1e-05 0.014 17.6 1.0 1 23 457 479 457 479 0.98

10 12 1.9e-07 3.8e-05 25.7 2.2 3 23 487 507 485 507 0.98

11 12 2.1e-06 0.00041 22.4 0.6 1 23 513 535 513 535 0.99

12 12 3.3e-06 0.00065 21.8 0.6 1 23 541 563 541 563 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	3e-05	0.0059	18.8	1.3	2	23	216	237	215	237	0.96
2	12	0.00013	0.026	16.8	0.7	1	23	244	266	244	266	0.97
3	12	2.4e-08	4.8e-06	28.5	0.4	1	23	282	304	282	304	0.99
4	12	4.2e-05	0.0082	18.4	1.3	1	23	315	337	315	337	0.98
5	12	0.00029	0.056	15.7	0.5	2	23	344	365	343	365	0.97
6	12	0.16	31	7.1	2.4	1	23	371	393	371	393	0.95
7	12	0.00027	0.053	15.8	3.0	3	23	403	423	402	423	0.98
8	12	3.5e-05	0.0068	18.6	1.3	1	23	429	451	429	451	0.98
9	12	7.1e-05	0.014	17.6	1.0	1	23	457	479	457	479	0.98
10	12	1.9e-07	3.8e-05	25.7	2.2	3	23	487	507	485	507	0.98
11	12	2.1e-06	0.00041	22.4	0.6	1	23	513	535	513	535	0.99
12	12	3.3e-06	0.00065	21.8	0.6	1	23	541	563	541	563	0.99

Sequence Information

Coding Sequence: ATGTATGATGATGACAACATAGAGTATAACCATTTGTGTCGAGTCTGTTTGGAAGAAACACTGGATTGGAATTCAATATTTGATAATTTGGATGAAACCCATAAAATTTCCGATGTCATCCTGCTTCTGGCACCGGTTATGGTGTGTATTGGGGATGGCCTTCCGAGCAGAATATGCGGAAACTGTTTGGAATacctaaaaatttattataatttgcgCAAAATTTGTGTCCGTTCCGATCAGAAACTGAGGGCCAAAGCCAAGCCGGAAcctattgtgaaaatggaaaatttcgatGATGGTTACGCAGGGATTGTGGGAAAAAATGGAGAGGACAGTTTTAATGACAGCCTCCTATCAAAAAAAGAAACATTCGACGAAGAACATTTGTATCCCGAAATAGAGGACGGATGCGAGTTGGATGATGATGTCGATCATGATCCTGGTATGTTGGAAATGGTGATTGCAGCCTCGGACACGGAAGATGAACTAAAACCCAAGTTTCGGAGTgagaaattaatcgaaattgaaattaataagcAAAGTGCGAGTGAAAGCGAGGAGGATTATAAATTCGAGCATTTAGAGAGCGACGACTATGCTCCGGACCCCTTGACCGGAAGGCGAGGCTCTAGGGGAAATTTGACGTGTCCAGAATGTGGTAAAATCTACAATAAAGCTTATCGGCTCAAGAAGCATATGGAACATCACGATACGGTGGGAAGGCCATTCAAATGTGATGTTTGCTCTTTATGCTTTCCATTGGAAAGTGCTCTAATTCGCCATATGACATTACATTCAGAAGCGATGAAAGCCTCAACAGCCTTAATCGAGGAGGAGGCATATAAATGCGAAGAATGTCCAAAAGTTTTCGATCGCAAATCATCCCTTGCGTCACACATGAAAGTGCACAAAAAGAACTGTTCTGCCGAAAACACggaatttaaatgcgaattgtgtcccaaattatttgaaactcGGAAAACGTTAATGCGCCACTGGAGTACACACCCGGAGATGAAAAAGCTCAAGTGTAGTATGTGTGAAAAGACATTCTCTTGGAAAGCACAATTAGTTGATCACATAAACAAGCACAACGGCATCACGCCATACGAGTGTATCGAATgtaaactaaaatttcattCTTCCGCTTTGTATCGCAAACACCTAGTAAAACACAggccgaaaaataaaaaagagagTTTGTGCCCGCATTGTGGCCGCGTTTTTCATAACAATACTGATATGAAGCAACACCTGACAATACATTCGACCGAGAAGGCGTACGCTTGCGATGAATGTCCCAGCCGTTTTGTATCGAAAAAATATTTAACGAAACATCGCCAAACCCATACAGGCGTAAAACCACACGTCTGCGATGTCTGCGGTAATGCATTCACAAAAGGAAGTTCACTTGTGAAACACAAAAGAACGCATACGGGTGAAAAACCATTTGGCTGTCCAACGTGCGATAAACGATTTAACTCGTCAGATCATTTAAAGCGGCACATTCGAATTCATACTGGTGAAAAACCGTACAAATGCCAATACTGTGAACGTGCTTTTGCTCAAAGTAGTGATTTAATTGGACACACCCgtaaacatttaggcgacaACATATACAAGTGTGAAAAATGTCCAGAAACATTTCGGCTTCAAGGTGAGCTACGTGAACATACACGTATGCATTTCTTAGCTGAACGGGAAACTAAGATTTCAGAAAATAGTGAATCAGGCGATCCCTCGGACATTCCAAGCCTTCAGTAA
Protein Sequence: MYDDDNIEYNHLCRVCLEETLDWNSIFDNLDETHKISDVILLLAPVMVCIGDGLPSRICGNCLEYLKIYYNLRKICVRSDQKLRAKAKPEPIVKMENFDDGYAGIVGKNGEDSFNDSLLSKKETFDEEHLYPEIEDGCELDDDVDHDPGMLEMVIAASDTEDELKPKFRSEKLIEIEINKQSASESEEDYKFEHLESDDYAPDPLTGRRGSRGNLTCPECGKIYNKAYRLKKHMEHHDTVGRPFKCDVCSLCFPLESALIRHMTLHSEAMKASTALIEEEAYKCEECPKVFDRKSSLASHMKVHKKNCSAENTEFKCELCPKLFETRKTLMRHWSTHPEMKKLKCSMCEKTFSWKAQLVDHINKHNGITPYECIECKLKFHSSALYRKHLVKHRPKNKKESLCPHCGRVFHNNTDMKQHLTIHSTEKAYACDECPSRFVSKKYLTKHRQTHTGVKPHVCDVCGNAFTKGSSLVKHKRTHTGEKPFGCPTCDKRFNSSDHLKRHIRIHTGEKPYKCQYCERAFAQSSDLIGHTRKHLGDNIYKCEKCPETFRLQGELREHTRMHFLAERETKISENSESGDPSDIPSLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01052492;
90% Identity: iTF_01052492;
80% Identity: -