Ngue033058.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nephrotoma guestfalica
Gene Symbol
ZFX
Assembly
GCA_963691935.1
Location
OY829914.1:172898752-172902092[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 4e-06 0.0008 21.5 4.4 1 23 212 234 212 234 0.99
2 17 0.23 45 6.6 0.7 3 23 238 255 237 255 0.89
3 17 0.001 0.2 14.0 0.3 1 23 261 283 261 283 0.99
4 17 0.0001 0.02 17.1 3.8 1 23 289 311 289 311 0.98
5 17 0.00011 0.021 17.1 0.9 2 23 318 339 317 339 0.97
6 17 2.4e-06 0.00046 22.3 3.8 1 23 345 367 345 367 0.98
7 17 4.3e-05 0.0085 18.3 2.2 1 23 373 395 373 395 0.99
8 17 0.78 1.5e+02 4.9 1.7 1 12 401 412 401 415 0.89
9 17 1.7e-06 0.00033 22.8 1.0 1 23 518 540 518 540 0.99
10 17 0.21 41 6.7 1.7 2 14 543 555 542 562 0.76
11 17 8.3e-05 0.016 17.4 0.5 1 23 567 589 567 589 0.99
12 17 0.00074 0.15 14.4 4.0 1 23 595 617 595 617 0.98
13 17 0.00011 0.021 17.0 1.3 2 23 624 645 623 645 0.97
14 17 2.5e-06 0.00048 22.2 1.1 2 23 652 673 651 673 0.97
15 17 9.2e-06 0.0018 20.4 1.2 1 23 679 701 679 701 0.98
16 17 0.026 5.2 9.5 4.9 1 23 707 729 707 729 0.98
17 17 0.00015 0.03 16.6 5.5 1 23 735 758 735 758 0.97

Sequence Information

Coding Sequence
ATGGCGCCGTactcattaaaacaaaaaatatttatcgtaaaacGGTATTATCAATGCGGTAATTCAACGGAAAAGGTTCAAAACGAGTTCCCTTTTGAATTTACTCGTAGCAAATCACCTACAGACGGCATGATTAATGAACTAGTGCAATTATTTGAAGAATTTGGCAGTGTATTCAAGTATCACAAGTTTCGATCGAACGATGTTTTAACGgacggaataaaaggaatcaaaaatgaaaatgatggcAATGAATGGAATACATACGAGCATGAAGAAAACTGCGTTGAAATTAAAACAGAGCCTGAAATATTTGCTCATGAATTTACGCCATATCTTGATGTCGACGACGATGATCATCACTTAGATAGTTTAAACGATTATGTGAAAGATGAGACTAGCACCGACAAATGTTCCTCCGAATCTTCTTCGGATGATAATACTAAAGCAAATGATGATAGAGATTGGGTAGACAAAGAGATTGATCAACAAATACAAGAATCGAATTCCACCATAAACACCATTAATACATTAGAAAATAACGACGATATGAACagaaaattattggatgagaTAATACATAGAACGAATAACGAGTTAGAGAAGGCTGAGGAGGCAACAAGTAAAACAGGTTTTAAATGTACCATTTGTAAGAAAGCATTTAATCGAAGACGGACATACACAAAGCACATGAATAGCCATAAAAATTCCTGTGAAATCTGTGGAATTAAATATCGTGATTATGCCAAGCACATGCGGAAACATACTGGCGAAAAGCCTTATCAATGTGCTGTTTGTAGTGCTCAATTCGTCGATATGAGCAGACTAAATAGTCACATGACAACGCATTCGGATGCACGCCCATTTGAATGCGATACatgcaaaaaaacatttaaatcacGTGATCGTCTACACGGCCACATGAAAATTCACTTAAGCGATCGACCAATCAAATGTGATATATGTGGAAAAGGTTTTCTACATAATGGCGATCTCAAGAAACATAGCCGTGTTCATACAGGTGAAAAGCCTTATGTATGTAGTTATTGTGGTAAATGTTTTGCATCCAGTCATTCTCTAACGGTACACAATCGAATCCACACGGGAGAGAAACCGTATAAATGCTGCTACTGTGATAAACAATTCAATGTGGCGGGCAGCTTAAATATTCATAAGCGAATTCATACAGGTGAAAAaccttttaaatgtaaattttgtgaaaaagcATTTTACGATACTGCCACATGTCGGGAACCTACACTGTTATTAGAAACTAAACTAGAAGATGAGCCACCTGAAAATAATCCCAGACAGAATACCGATGTGAAAGTTGAGCCACATTTACTGTTTAACCAATTAAGGGTTAAAGATGAACATGCCATTAAAGTTAAAGAAGAGGATTTGTACAGTGGTATCAATACCGAAGATGTAGATGTAAATAGTACATCAGATGATTGTACTATTTCAGATGATACGGACGAGGAAGTTGATAAAATCTTATTAAAAGATAATAGACCGAATGATAAGTCGCCAGAAAATAGAAAgcatatttataaatgtaacgAGTGCAGTAAAATATTTGAACGTGAAATACAATTAAAACGTCACATAAATTCGCATGCAAAAACCTGTGAGATCTGCGGGAAGAAATACCGAGATCGAGAAATACATCTGCGGAAGCATACGGGAGAAAAACCTTTTCAATGCCAACAGTGTGGTGCCCAGTTTATTGATTTGACTCGGCTAAATAATCATATTAAAACTCATTCAGATGAGCGACCATTTGAATGCGATGTATGCCATAAAACCTTTAAATTGCGTGATCGTCTTCGTGGCCATAAAAAGACTCATATTGTTGATCGCCCTATAAAATGTGAAGTGTGTGGTAAAGGCTTCCTGCACAACGGAAGACTGAAAAATCACATGCGAATGCATACCGGTGAAAAACCATcggtttgtaatttttgtggtaAATGTTACGCTTCGAATGATACGTTACGAGTTCATATTCGAATACACACTGGTGAAAAGCCATACGCATGCACATTCTGCACCAAAAAATTTAGCTCATCGGGAAGCTTGAATATTCATACAAGGATTCATACCGGCGAAAAACCGTACAAATGTCAGTACTGTGAAAAAGCTTTTCATGATTCGGCAACTTGTAGATCACATGAACGGGTGCATACTGGAAACTATCCGTACAAATGTAAACTTTGCGGGAAAGCACATAATCATCCTAGTAATTTAAAGTCACATATGCGGCATGCACATCGAGAAGAACAAgcctaa
Protein Sequence
MAPYSLKQKIFIVKRYYQCGNSTEKVQNEFPFEFTRSKSPTDGMINELVQLFEEFGSVFKYHKFRSNDVLTDGIKGIKNENDGNEWNTYEHEENCVEIKTEPEIFAHEFTPYLDVDDDDHHLDSLNDYVKDETSTDKCSSESSSDDNTKANDDRDWVDKEIDQQIQESNSTINTINTLENNDDMNRKLLDEIIHRTNNELEKAEEATSKTGFKCTICKKAFNRRRTYTKHMNSHKNSCEICGIKYRDYAKHMRKHTGEKPYQCAVCSAQFVDMSRLNSHMTTHSDARPFECDTCKKTFKSRDRLHGHMKIHLSDRPIKCDICGKGFLHNGDLKKHSRVHTGEKPYVCSYCGKCFASSHSLTVHNRIHTGEKPYKCCYCDKQFNVAGSLNIHKRIHTGEKPFKCKFCEKAFYDTATCREPTLLLETKLEDEPPENNPRQNTDVKVEPHLLFNQLRVKDEHAIKVKEEDLYSGINTEDVDVNSTSDDCTISDDTDEEVDKILLKDNRPNDKSPENRKHIYKCNECSKIFEREIQLKRHINSHAKTCEICGKKYRDREIHLRKHTGEKPFQCQQCGAQFIDLTRLNNHIKTHSDERPFECDVCHKTFKLRDRLRGHKKTHIVDRPIKCEVCGKGFLHNGRLKNHMRMHTGEKPSVCNFCGKCYASNDTLRVHIRIHTGEKPYACTFCTKKFSSSGSLNIHTRIHTGEKPYKCQYCEKAFHDSATCRSHERVHTGNYPYKCKLCGKAHNHPSNLKSHMRHAHREEQA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
-
80% Identity
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