Ngue033343.1
Basic Information
- Insect
- Nephrotoma guestfalica
- Gene Symbol
- -
- Assembly
- GCA_963691935.1
- Location
- OY829914.1:177439153-177448088[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.0049 0.97 11.8 0.2 5 23 136 154 134 154 0.95 2 20 0.15 29 7.2 0.7 3 23 158 175 156 175 0.73 3 20 0.024 4.7 9.7 1.2 1 23 181 203 181 203 0.98 4 20 2.8e-05 0.0056 18.9 2.4 1 23 209 231 209 231 0.97 5 20 0.00054 0.11 14.9 0.6 2 23 238 259 237 259 0.98 6 20 0.00019 0.037 16.3 0.7 2 23 406 427 405 427 0.97 7 20 0.48 94 5.6 4.6 2 23 430 448 430 448 0.89 8 20 0.0088 1.7 11.1 0.8 1 23 454 476 454 476 0.96 9 20 0.0059 1.2 11.6 4.2 1 23 482 504 482 504 0.97 10 20 0.00013 0.025 16.9 1.1 1 23 510 532 510 532 0.98 11 20 4.9e-08 9.6e-06 27.6 0.4 2 23 539 560 539 560 0.97 12 20 0.0015 0.3 13.4 0.8 2 23 680 701 679 701 0.96 13 20 4.3 8.4e+02 2.6 2.9 2 23 705 723 704 723 0.77 14 20 0.048 9.4 8.7 0.3 1 20 729 748 729 751 0.93 15 20 1.3e-05 0.0025 20.0 3.7 1 23 757 779 757 779 0.99 16 20 4.1e-05 0.0081 18.4 0.6 2 23 786 807 785 807 0.98 17 20 1.8e-05 0.0035 19.5 1.6 3 21 815 833 813 835 0.94 18 20 0.00028 0.054 15.8 1.3 1 23 841 863 841 863 0.98 19 20 0.00017 0.033 16.5 2.6 1 23 869 891 869 891 0.99 20 20 0.00019 0.038 16.3 5.2 1 23 897 920 897 920 0.97
Sequence Information
- Coding Sequence
- ATGACAGCGTTCACATtactcgaaaaaatatttattgtaaaacgGTATTATCAGACTGGAAATTCATCCGAACACGTGGAAAATGAATTCGTTCAACAATTTCAAAGTGGTCATTTATTAAACGCGGCTGTTATTAATCAATTGGTtggtttatttgagaaatttggtAACGTAAATCAAGAGGACTTAGAATTGAAGTTAACCGTTGATACACTGGTgaaagatgaatttaaaaaagattACAAAACAATTGAGAATACTGATTATTTGGATGAAAGTCTTACCCTTCCATTAGATAACGAACTTGATTTTGACGAGAGCGGTTGTGAAGATGCGGATGAAGAAAGTGCAGAAACACCACTATTCACTGTAGAAGAAGTTGAATCTAAGTCAAGTTCACAAAtcatttgtgataaaaaattcaaacgtcGTTCAGAAAAAATAACGCACATGATTGGACATAATAATACGTGCGAAATATGTGGCAAAAAGGCGAGAAATCTAGTAAATCATATGCAAAAGCATACAGGTGAAAAGGCATATAAATGCACACAATGTATTGCGCGGTTTTCAACATCAATGAGATTAAAAAATCACTTGGCTTCTCATTCAAACGATCGTCCATTTAATTGTAGCATTtgtgataaaagttttaaaacaaatagtCAAATGTACGGGCATAAACAAACTCATTTAGCTGATCGACCTATAAAATGCGAATTATGCGGTAAAGGATTTCTCCGTAATCGCGAGAAAAATGCTCATATGAGAACACACACAGGTAATTCGACACAGTCAGTACAAAAAGAATTTCCTAGTGAGTTTAATCAATATGCATCGcctacaaatgaaaatattgaagaGTTAGTGCAATTATTCGAGGAATTTGGAAGCGTAATTAAGTTAAATGAAACAGAAACAATTTATGAAGCAACTAGCAGCTATttgCGGAAAGAGGATGATTTGGAAATCAAAGAGGAACCAACACTTGAAGTTTACGACCACCCGCATCCTGTGGCGGACGaagtttttcttaataaatctattgataacggacaaaataatttaagtagtGATATTAGTTGTAGCGATGATGGTGAAGATGAGGACAGAGATAAATCATATACAACGAGTGATGAGGCGAAGGATACTCTATCCTTAGCTAATGAACAGGATCCGGATAAATCTTCAAGtaacaaaacaaagttaatattaaaatgcGAGGAATGCGGAAAAGAATTTGATCGTCGAGCTCGATACCTAAGACATAAAAACGTACATAAAAACCGATGTGatatttgtggtaaaaaatTTCACGATCGCGAGAAACATATGAAGAAGCACACAGGTGAAAAAACATTTATGTGCATGCTATGTAATGCTAGATTTATCAATATAAGTAGATTAAATCACCATATGATCGGACATTCAACAGAAAGGCCGCATGAATGCGACGtttgccataaaaaatttaaatctaccGATGTATTACGTGGACACAAGAAAATACATTCGACTGAACGACCACATAAGTGTGATCAATGTGGTAagggatttttaaataaaaatgatttggcTAAACATCTAAATGTACACACGGGTCAAAAACCGGCTGTTTGTCAGATATGCGGTAAAGGTTTCTCGTCAAACGATTCGCTCAAAGTTCATATGCGAACACATACTGGTGGACTACTGTACATACTGTTTATATTTAAGGAAGAGGAATGCGAAGTAAAATCTGAGCCAGTtaatttccttatcaataatATCGGAATTTGTGAACCGCAACATGAAAACAATGATGTCGATACCATCAAATTTGATTCAGAGTTGGACCTGTTTGCCGGAGTGAACAGTCACAATGATTTTAGTGAGGTGCTTGTGCCCACTAAAATTGGGGAGATTAATAAATATAACTCGATTGGCGATAATTCTGCAAGCAATGATTGTTCAAATGGAGGTAATcctttaaaatatgaatttttagaAGACGCtgcattagaaaataaaaaagaagatgTTAATCCTGTAGTTCTATCTTGTAAGATTTGTCGTCAAGAATTCGACAAAGAAATGTATCTTAAACGGCATATCAAGGCACATAGCAAAACATCATGTGAGATATGCGGCAAAAAATATCTGAATCGAGAGAACCACATGAAAAAGCATTCGGGTGAAAAATCGTATCAGTGCACGATATGCGGATCGCGATTTTTAAATATGAGCCGACTAAATAGTCACATGCCAATACACTCAGAAGAAAGGCCATTTGAATGTACCACATgccaaaagaaatttaaatctcGCGAAAGATTACGCGTACATCAGAGGACACACACTACGGACCGGCCGAATAAGTGTGAAGTATGCGGTAAAGGATTTTTACAGAAATACGatctaaaaaaacatttaaacgtGCACACGGGCGAAAGGAAATCAATATGTAGCATATGTGGCAAATTTTTCGTTTCCAATGATTCACTAAAAGTTCATATGCGATGCCATACTGGTGAAAAACCATACAATTGCAGGTATTGTGAGAAACATTTCAGCTCAGCGggtgttttaaaaattcacgAACGGATTCATACTGGtgaaaaaccttacaaatgcaaatattgtgttaaagaattttatgaTTCATCTACAAGGAGGGCACATGAAAGAACACATACCGGAGAGTATCCATATAAATGTACCCTTTGTGGTAAAGCTCACAATCACCCTAGTAATTTAAAATCACACATGCGACATGCTCACCGAGAAGCATTAATAATAggttttaagtaa
- Protein Sequence
- MTAFTLLEKIFIVKRYYQTGNSSEHVENEFVQQFQSGHLLNAAVINQLVGLFEKFGNVNQEDLELKLTVDTLVKDEFKKDYKTIENTDYLDESLTLPLDNELDFDESGCEDADEESAETPLFTVEEVESKSSSQIICDKKFKRRSEKITHMIGHNNTCEICGKKARNLVNHMQKHTGEKAYKCTQCIARFSTSMRLKNHLASHSNDRPFNCSICDKSFKTNSQMYGHKQTHLADRPIKCELCGKGFLRNREKNAHMRTHTGNSTQSVQKEFPSEFNQYASPTNENIEELVQLFEEFGSVIKLNETETIYEATSSYLRKEDDLEIKEEPTLEVYDHPHPVADEVFLNKSIDNGQNNLSSDISCSDDGEDEDRDKSYTTSDEAKDTLSLANEQDPDKSSSNKTKLILKCEECGKEFDRRARYLRHKNVHKNRCDICGKKFHDREKHMKKHTGEKTFMCMLCNARFINISRLNHHMIGHSTERPHECDVCHKKFKSTDVLRGHKKIHSTERPHKCDQCGKGFLNKNDLAKHLNVHTGQKPAVCQICGKGFSSNDSLKVHMRTHTGGLLYILFIFKEEECEVKSEPVNFLINNIGICEPQHENNDVDTIKFDSELDLFAGVNSHNDFSEVLVPTKIGEINKYNSIGDNSASNDCSNGGNPLKYEFLEDAALENKKEDVNPVVLSCKICRQEFDKEMYLKRHIKAHSKTSCEICGKKYLNRENHMKKHSGEKSYQCTICGSRFLNMSRLNSHMPIHSEERPFECTTCQKKFKSRERLRVHQRTHTTDRPNKCEVCGKGFLQKYDLKKHLNVHTGERKSICSICGKFFVSNDSLKVHMRCHTGEKPYNCRYCEKHFSSAGVLKIHERIHTGEKPYKCKYCVKEFYDSSTRRAHERTHTGEYPYKCTLCGKAHNHPSNLKSHMRHAHREALIIGFK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -