Basic Information

Insect: Nephrotoma guestfalica
Gene Symbol: -
Assembly: GCA_963691935.1
Location: OY829914.1:4937699-4939564[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 4.7e-05 0.0092 18.2 3.9 1 23 144 166 144 166 0.97

2 14 0.00035 0.069 15.4 0.8 1 23 173 195 173 195 0.98

3 14 6.2e-05 0.012 17.8 1.8 1 23 244 266 244 266 0.96

4 14 0.0006 0.12 14.7 1.2 1 23 273 295 273 295 0.98

5 14 6e-06 0.0012 21.0 0.7 1 23 312 334 312 334 0.99

6 14 1.5e-05 0.003 19.7 1.0 1 23 343 365 343 365 0.98

7 14 2.9e-05 0.0058 18.8 0.2 1 23 371 393 371 393 0.98

8 14 7.5e-05 0.015 17.6 2.5 1 23 399 421 399 421 0.98

9 14 3.5e-07 6.8e-05 24.9 0.4 1 23 427 449 427 449 0.96

10 14 0.00058 0.11 14.8 2.4 1 23 455 477 455 477 0.97

11 14 9.2e-05 0.018 17.3 2.7 1 23 483 505 483 505 0.98

12 14 0.0001 0.02 17.1 2.3 3 23 513 533 511 533 0.98

13 14 6.5e-07 0.00013 24.1 0.6 1 23 539 561 539 561 0.99

14 14 0.00018 0.035 16.4 2.8 1 23 567 589 567 589 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	4.7e-05	0.0092	18.2	3.9	1	23	144	166	144	166	0.97
2	14	0.00035	0.069	15.4	0.8	1	23	173	195	173	195	0.98
3	14	6.2e-05	0.012	17.8	1.8	1	23	244	266	244	266	0.96
4	14	0.0006	0.12	14.7	1.2	1	23	273	295	273	295	0.98
5	14	6e-06	0.0012	21.0	0.7	1	23	312	334	312	334	0.99
6	14	1.5e-05	0.003	19.7	1.0	1	23	343	365	343	365	0.98
7	14	2.9e-05	0.0058	18.8	0.2	1	23	371	393	371	393	0.98
8	14	7.5e-05	0.015	17.6	2.5	1	23	399	421	399	421	0.98
9	14	3.5e-07	6.8e-05	24.9	0.4	1	23	427	449	427	449	0.96
10	14	0.00058	0.11	14.8	2.4	1	23	455	477	455	477	0.97
11	14	9.2e-05	0.018	17.3	2.7	1	23	483	505	483	505	0.98
12	14	0.0001	0.02	17.1	2.3	3	23	513	533	511	533	0.98
13	14	6.5e-07	0.00013	24.1	0.6	1	23	539	561	539	561	0.99
14	14	0.00018	0.035	16.4	2.8	1	23	567	589	567	589	0.99

Sequence Information

Coding Sequence: ATGGAAAATATATATGAGAGTACGTGTCGGATTTGCTTGGTAGCGACCAATGTTGACGGAAGTCAGGGTATTTTTGATGTATTCTCTAATGAGTTAACTTACTCCGATGTTGTTATATTGATTGCTTCGAttgaaataaaaccaaatgatgGCCTACCGAACAAAATATGCACAAATTGCTCGAATCGTGCAAATGATGCTTACAACTTTCGTAAACAATGTATCAGCTCAGATAAGCTGATGAAATCTAAGACCGAGGCACCTAGCATTATAAAAGTGGAAGTTGCAGAAGCAGACGTCAAAAATGAGTGCTCCGACGACgatgataattttaatgatagttTGAATGAGGTAGATTGCAATCCTCTTGACGAAATAGAAGACTTGGCTGAAGAAGTGGAACCCCCGCGACACAAAGTGAAAAAGGTTCATAAATGTGAAATTTGTTCCAAAGTGTTTGACAAACCATTCCACCTACAACGGCATTCAAATGTTCACACCGCCAATGGTAAAGAATTCGAATGTGATATATGCCATAGATTTTTTGCTTTGGAAGGTACTCTCATCAAACATAAAATGATACATGATGAACCACCAGATGAATGCGTAGAAGATCAGCAACAAAACAGTGAAAGTCATGATGAAGATGATGATATAAATGATGAAGATTATAAACCAACTCTCGAAGCGGCTCCAATACCTGAAAAACCTCGCAAAGTTCGAAAGACTCATAAAtgtgaaatttgttctaaaGTATTTGATAAACCATCACGACTACAACGACATTCATCTGTACATGCTGCTAATGGAAAAGAATTTGAGTGTAATATATGCCACCGTTTTTTTGCTGCTGGAAGCACTctcattaaacataaaataacgcATGCGGCCCAATCTGAGTTTAATAATGATAGTACACTTCCAAAAAAACcgtttaaatgtttcgaatgtgACAGAGTTTTTGAGAAGCAGGAGTCTATGGCATCTCATATGAGAATACATAAAACAGGTTCGACAATTAGAGAGTATAAATGTGATTACTGCCCAAAAGTATTCACTGAAGTTAATTTATTGACAAGACATTCCAAATCGCATATTGAAATGAAAGTTTTTAAATGCGAAATTTGTCCTGAGAGTTTTGGATCTAGACCGCAATTGATTGATCATACGAATAAACATAAAGGCTTGAAACCTTATGAATGTAccatatgccagaaaaaatttcattcatctACTGTGCTAAATCAGCATATCAAAATTCACACTGATGATAAATCCTATTTGTGTCCACAGTGTGGTAAAGGATTTAAAAATAACGGATATTTAAAACAACATATGATCTCACATTTgggcgaaaaaatatttgcatgtcCTCAATGCCCGAATAAATACTGCACTAAAGgaaaattaaaatctcatCTTCAAAGTCACTCTGGATTAAAACCCTTTGTCTGTGAACAATGTGGATCTAGTTTTACAAAGCATTATACATTGACGGTACATAAAAGAATTCATTCGGGCGAGAAACCATTCGGATGCGATACTTGTCCTAAacgatttatttcattaaatcatTTGAAACGGCATTCCCGTGTTCACACTGGTGAGAAACCATACAAATGTCAATATTGTGAACGGGCATTTGCGCAAAGTGGTGATCTCATAAAGCATACTCGATCTCACATTGGAACGAACACTTATAAGTGTGACAAATGTGAATCAACGTTTCGTCTTCACGGGGAGCTTAAAAAACATATTCAAATGCATTTCTTAGCTGAAAAGGAAATGAACGaaacaaaaagtgaaaattaa
Protein Sequence: MENIYESTCRICLVATNVDGSQGIFDVFSNELTYSDVVILIASIEIKPNDGLPNKICTNCSNRANDAYNFRKQCISSDKLMKSKTEAPSIIKVEVAEADVKNECSDDDDNFNDSLNEVDCNPLDEIEDLAEEVEPPRHKVKKVHKCEICSKVFDKPFHLQRHSNVHTANGKEFECDICHRFFALEGTLIKHKMIHDEPPDECVEDQQQNSESHDEDDDINDEDYKPTLEAAPIPEKPRKVRKTHKCEICSKVFDKPSRLQRHSSVHAANGKEFECNICHRFFAAGSTLIKHKITHAAQSEFNNDSTLPKKPFKCFECDRVFEKQESMASHMRIHKTGSTIREYKCDYCPKVFTEVNLLTRHSKSHIEMKVFKCEICPESFGSRPQLIDHTNKHKGLKPYECTICQKKFHSSTVLNQHIKIHTDDKSYLCPQCGKGFKNNGYLKQHMISHLGEKIFACPQCPNKYCTKGKLKSHLQSHSGLKPFVCEQCGSSFTKHYTLTVHKRIHSGEKPFGCDTCPKRFISLNHLKRHSRVHTGEKPYKCQYCERAFAQSGDLIKHTRSHIGTNTYKCDKCESTFRLHGELKKHIQMHFLAEKEMNETKSEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01052488;
90% Identity: iTF_01052488;
80% Identity: -