Basic Information

Insect: Nephrotoma flavescens
Gene Symbol: THAP4
Assembly: GCA_932525705.1
Location: CAKOBH010000414.1:328594-330707[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 7.6 1.4e+03 1.8 0.1 5 16 161 172 160 174 0.80

2 11 0.0081 1.5 11.2 1.8 2 23 335 357 334 357 0.94

3 11 0.04 7.3 9.0 0.7 2 23 363 385 362 385 0.92

4 11 0.025 4.5 9.6 0.6 1 21 413 433 413 434 0.94

5 11 1.6 2.8e+02 4.0 1.2 2 21 442 461 441 462 0.90

6 11 0.00021 0.038 16.2 3.2 1 23 490 512 490 512 0.98

7 11 0.11 20 7.6 0.7 2 19 521 538 520 541 0.93

8 11 0.0024 0.43 12.8 0.7 1 23 570 592 570 592 0.96

9 11 9.9e-07 0.00018 23.5 1.4 1 23 598 620 598 620 0.98

10 11 0.00075 0.14 14.4 2.0 1 23 626 649 626 649 0.96

11 11 0.46 84 5.6 0.1 1 16 655 670 655 672 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	7.6	1.4e+03	1.8	0.1	5	16	161	172	160	174	0.80
2	11	0.0081	1.5	11.2	1.8	2	23	335	357	334	357	0.94
3	11	0.04	7.3	9.0	0.7	2	23	363	385	362	385	0.92
4	11	0.025	4.5	9.6	0.6	1	21	413	433	413	434	0.94
5	11	1.6	2.8e+02	4.0	1.2	2	21	442	461	441	462	0.90
6	11	0.00021	0.038	16.2	3.2	1	23	490	512	490	512	0.98
7	11	0.11	20	7.6	0.7	2	19	521	538	520	541	0.93
8	11	0.0024	0.43	12.8	0.7	1	23	570	592	570	592	0.96
9	11	9.9e-07	0.00018	23.5	1.4	1	23	598	620	598	620	0.98
10	11	0.00075	0.14	14.4	2.0	1	23	626	649	626	649	0.96
11	11	0.46	84	5.6	0.1	1	16	655	670	655	672	0.85

Sequence Information

Coding Sequence: ATGCCGTCGACTTGTATTATTCGCGGCTGTAAAACAAAATACGCAACTGATGTTTCGTTTCACAAGTTTCCCGTAAAAAATACCAAATTACTTAAGCAATGGATAAAATTTGCGAACCGCGGCGAGACATGGAAGCCGACACGATGGACTTCCATTTGTAGTTCACATTTTCAACGGTCAGATTTTCAGGATCGTAACAATCAGCGGAAAACACTGAAAAAATTTGCTGTGCCCTCGATTAATGAGGCGGCGGTCGTGGACGATGTGTACCAAACAAATAATGATTGTAGTGGCGAAATAGGGACTCAAGAATATTCAACTCCGATTCTGTATAATACATACGTAGAACCGATGTGCCATTTTTGTGGTGACAAAGCGCACGTATTCAACTTCTCAAAATTTAATTTAATACATTTCAGTGCGATCCTGAAACAGTATCCTTACTTGAATTTGAATGAGTATAACGAGGCTCAAATTAAAATTTGTGATAAGTGCTACAACACGATTGTAAATTTTGAAGTTTTTCTGACGAACTTCTTAAAATTGCACGGTTGTAGCGAAGATATAGAGCATTCTGTTGAGTCGCCAGAATTCGGCGACGATACCTATAACGATACGAGTAAAATACCTAAACTGAAAATAAAACAAGAACCAATAACGGTTATAAAAGAAGAGATTTTGGAGCCAGGACAACGATTTATCCCGTCTGAACTATTGACAGGCCAATCATTGAGTAATAATGATGTAATCGAAGTAACACCTCCCAATGACGTCATAAACATTATCGAGGAGGATAATATTCAGGATACTGGTGAAATTCAAGAGGAATTCGAGTTTGAATTGAAGTCTGAGGAGGTTAAAACCGAGGCGGTCGAGACGTGTGATATTCGTTATATTGAAAATGCTCGACATGATCATTCTTATGCTAAATACACAGGTGATATGCGACACGACGGTTACGAATACAGTGTTGATGAAAAACCGGTATTTTTTGATCAGATCACGTGTACCCTGTGCAATTCCTACTTTGAGGATCAGCACCAGTTGGAGAAGCACACTAGTATATTTCACACGTTTCACAGTCAAACCTGCAACGAATGCTATCTAGAGTTCAAAACTCTGTACGATTATTTAATCCATAAAAACGACACGCATGGACGAATTAAAACGACTGGTGACGATGAACTCACCGTAGTGTATGATACGACTCCCACCAAAGAGTCGATCGATCCTAAATTTATCTGTGATTTATGTAATGAGATTCTGGTCACAAAGACGTCGCTGAATCATCACAAGAAGTATTTGTGCCAATTCAAGCTACAGTACTGTAAAGTATGTAAAACGGGATTCGAAGACATGGAAGTGTTCCAAACGCATACGTGTAGTAAAAAGACGATGCAACGGGTTGGCGGCGGCAATTTGATACGAAATAAAACGGCAAAGCTAAATTTTATGAAGAATGGCCGGTACACCTGTAAATTTTGTTCCCGTACTTATGGAAAATATTACAACCTACTGAAGCACATACGTCTCCATCGTCCGATACAGGAATGGAATTTAAAATGCGGCAATTGTGGCATGCTGTTCGATCGGATCTACGATCTGAATCAACATTGCCGTCGAAGCATCTGCACAATCAATCCTAATGAACCGCTAATAACCAAATTTAATTTCAATTCCGCGGGTTTTAAACGACAAAAACTCAAATACGTCTGCCTCAAATGTAACAAAATTTTGTCGTCGAGTAAAAGTCTTAAGCTACACGAGTATATTCACAGTACGACACGGCCGTTTGTTTGTGAAACGTGTGGCAAAAAATTCCGATCACCGATTAATTTGAGGCAACACAAAAAATCGCATATCGATCATAAATCATTTGCGTGCAACTACTGCGAGAAGAAATTCAAATGGAAAACGAATTTGAGATTGCACGTGAATTCCTTCCATTTAGATATTAAGCCGCATGCATGCCCGAACTGTAATTACCGATATGCGAGGCGGCGGGAAATGTTAAGATGTAAGCATTCGATTCAATTATGTAATAAAACGTGA
Protein Sequence: MPSTCIIRGCKTKYATDVSFHKFPVKNTKLLKQWIKFANRGETWKPTRWTSICSSHFQRSDFQDRNNQRKTLKKFAVPSINEAAVVDDVYQTNNDCSGEIGTQEYSTPILYNTYVEPMCHFCGDKAHVFNFSKFNLIHFSAILKQYPYLNLNEYNEAQIKICDKCYNTIVNFEVFLTNFLKLHGCSEDIEHSVESPEFGDDTYNDTSKIPKLKIKQEPITVIKEEILEPGQRFIPSELLTGQSLSNNDVIEVTPPNDVINIIEEDNIQDTGEIQEEFEFELKSEEVKTEAVETCDIRYIENARHDHSYAKYTGDMRHDGYEYSVDEKPVFFDQITCTLCNSYFEDQHQLEKHTSIFHTFHSQTCNECYLEFKTLYDYLIHKNDTHGRIKTTGDDELTVVYDTTPTKESIDPKFICDLCNEILVTKTSLNHHKKYLCQFKLQYCKVCKTGFEDMEVFQTHTCSKKTMQRVGGGNLIRNKTAKLNFMKNGRYTCKFCSRTYGKYYNLLKHIRLHRPIQEWNLKCGNCGMLFDRIYDLNQHCRRSICTINPNEPLITKFNFNSAGFKRQKLKYVCLKCNKILSSSKSLKLHEYIHSTTRPFVCETCGKKFRSPINLRQHKKSHIDHKSFACNYCEKKFKWKTNLRLHVNSFHLDIKPHACPNCNYRYARRREMLRCKHSIQLCNKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01455240;
90% Identity: iTF_01054797;
80% Identity: -