Basic Information

Insect: Nephrotoma flavescens
Gene Symbol: Hivep1
Assembly: GCA_932525705.1
Location: CAKOBH010000245.1:40279-48324[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00083 0.15 14.3 2.1 1 23 386 408 386 408 0.97

2 8 0.00053 0.095 14.9 2.3 1 23 414 438 414 438 0.90

3 8 0.0043 0.78 12.0 1.0 1 20 730 749 730 750 0.95

4 8 3.4e-06 0.00061 21.8 2.0 1 23 1524 1546 1524 1546 0.99

5 8 3.7e-05 0.0067 18.5 3.2 1 23 1552 1576 1552 1576 0.92

6 8 0.0029 0.52 12.6 1.3 2 23 2029 2050 2028 2050 0.97

7 8 0.0064 1.2 11.5 1.3 1 23 2056 2080 2056 2080 0.91

8 8 0.0057 1 11.6 2.6 1 23 2101 2125 2101 2125 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00083	0.15	14.3	2.1	1	23	386	408	386	408	0.97
2	8	0.00053	0.095	14.9	2.3	1	23	414	438	414	438	0.90
3	8	0.0043	0.78	12.0	1.0	1	20	730	749	730	750	0.95
4	8	3.4e-06	0.00061	21.8	2.0	1	23	1524	1546	1524	1546	0.99
5	8	3.7e-05	0.0067	18.5	3.2	1	23	1552	1576	1552	1576	0.92
6	8	0.0029	0.52	12.6	1.3	2	23	2029	2050	2028	2050	0.97
7	8	0.0064	1.2	11.5	1.3	1	23	2056	2080	2056	2080	0.91
8	8	0.0057	1	11.6	2.6	1	23	2101	2125	2101	2125	0.93

Sequence Information

Coding Sequence: ATGGATGATTCACCAGCGTATTTAATAAGCTATTCACGTTTTGAGTATGCTGAAATATGCACGAAAATTAATCATTGTTCTAGTTTAAAAATTCGCCAGAAATATCATGATTCAGATGATAGGGGTGACAAATCAGCAGCACCACTAATCGATATAGTACAAAAAAATAGCAGTAATAATAACAATAATGAGATAGATGAACGGCATAATCGAAGGGACGAAGATTTATTGAAATCACATCATATTCATAATCAGCACCAGCCAATAAGAGAACTTCCAAAATTTGTAAATAATAACAATAGTAGTGCAACATTTGATGATCGAAAGTACCTGCATAAAAAATTTAAGCGACTCGCTAGTACTACACTAAATGATATACATTTAGAAAATAACGGTTTAGTGAATAATAGTAATTTAATAGTGAATAATAATAGTAATAGTAATATCAGCCCACCATTATCAAGTTTTACATCAACATCATCACAATCTCCTCCCAGTGTTGTGCCAACGGCAATAACCACAACAACAACAATCGCACCGACGACCACACTAATATCACCTCCAAATTTACATCATATTCAACATCAGAAACATCAACACAGTGAGCCGGGAAATTGCAATCCAGTGCAATTAATGAATAGCGCGAATAATAGTACCACTAGTCCCAAATACAACGGACATCAAGAGAATCATCATCATATTCATAATAGTTCAAATATTAATTACAATGAATTGAGGTATAACGATAGTATAACAGTTTCAGGCCAGATTGTTACTACACAGCAACCACACATTGTCCAAACCGGCGGTAATAATGTAATTTATGTATCTCTGCGCCCATCCAATCTGGTCCAACAACAATTGCCGCCATCACAATCTCCGTCGATATTATCACAGCAGACTAATTACGTTAAGGAGGAGGAGGAGTCATCATCAATAGATGATATTTCATCGTCAGGAATGGGTATTAATGAAAGTTACACCCATCAAAATCATTATCAACCGCAACATTTACCCAATGGTATTTTGGCACAAGGCAACTCGTCTACCACAACAACACTGATTTCAGCACCAAAATTAATAAGTTCAATGCCGAGTACAGTGCCATCGTCCGGAGCAACTTCGGCAACTGCACCTTCATCTACAAATGGCCGGCATGTCTGTCCGTATTGCCAAATGAATTGTTCTAAACCGTCGGTCCTACAGAAGCATATCCGGGCACATACAAATGAGAGACCATATCCATGTGGACCGTGCGGTTGTGCATTTAAAACAAAAAGTAATCTCTACAAGCATCAAAGATCCCGAACTCATACTCTTAGAACCCAAGGTGGTGAGCCAGCGGAGGATGATGTGTCACAAGGGTCTGATCAAGAGCAAGATCAAGATCAACAATTTAATCAATTCGATAGTTTAACTCATCCTCAGAATCCTAGTATGGAAGTAGTTGAAATGAAGTACTCATCACAACAATATATTCATCAGCAACCACTGCCGAACCATCAGCCACAACAACAGCCTATCCAAGAGCAAAAGCCATACAAACCAAAATTTCACCAAATTAACGCCTATAAACCGTATGGTGATCAAGGTAACAGCAATAGTAGCAGTTGTAGTGGAACCGTAAAAGATGAGCCCAAACAACAAAGCCATATTATTGCAACAACAAGTATTAGTTTTATTGCAAATTCTTCGGTAATGATTAAGCCACAAGTTCCAAATGTAGTCTCGACTCCACCAAAAAATTTAGATTTTGCTTCGCACATCACGAAATTAATATCCGATAATGAAGCAATTGTCGAAGGTGGTAAACCGCCGCTTCCAAAGAAAACCCTTAAAACATCATTTCGTGGTACAATTCCAGAAAATTCAAGTCCAAAACTGGCATTGGCCTTATTGCACAAGGAAATAAATGCGAATGCAGCTGGGCAAACGTCCAACAATAAATTAATAGTTTCTAACAGTCGATATGTGAATTTTCCGACTAGCATAAATAATCCGGGTACATCGAGTCAGGCAGATACCATCGCGGGTCCTAGTTTAACGCAACCATTAAATTTAAGCAAAGTTGTGGTCAAAAATGTGCCCAATCATCCACAAAATCCAGAACGATCCATTATAAAAGATTTGCTTTTGAATACGAAAGAATTTGGAGCAGTGGATGGTATGGAGGCGGCCGAATCACTATATCACTGTCCATTTTGTAAAATCAGCTTTCGTAATGCTGAAACACTGAAGTACCATACAATTTGTTATTGCCAAGGAAATCAAGCGAACAGTCCGCATAATAGTGCATCAGCTAGTCCCGCAGCATCACCTTCTCATCAATATATGAGGACGCACAGTAACTCAGAAAGCTATAACCCAAATAGTCTAGCAAAATTGGCTAGTACATCTCTGCGTCAGCATCCTTATCGCACGCCCACGAAATTATTTAATTTGGCTAAGGCTAATATAAAGCCGACGCGTCCAAGACTCGAAAATATCGTGATTAATGAGAAACAAGATGAAATTGTAAATCGAAATATTGATATTGTGCAAGCACCTTTACCTTCACCAGGACCATTACTGGGGAATACTCGTCTCGTTGATTCGTACTATAAAACACCTAGTGACCGAGGATTGATGGAAGAAAAAACGCAAGGCGTTTCATTGTATATTGTTCAAACAAATCAGGAGCGCAGTCCCTCGCCGATGGAAACGCAAAGTCATAATTTTGCGTTACCCACAATGATCAGCGATGACCCGGCAATATCTCACCGAAGAAATTCAAACAGTGTAAATAATTTTCAAATGTTTGGAGGTGAAGTTCAAGTCATCGAAAAAAAGAATGATTTATTTCCAACGTACGGTGCGGGCGGTTCAGTAACATCGCTGTCACCGTCAGATTCTGAACCTAGTCCAATACTTGTGCGAACAGGATTATTTTCAGGTGGTTCGCTTCAGTTACCACAGACGCCTAAAGAAAAAATTAATCGTACGCCACTAACACCTAAGCTACTCGGTACCCCGGCAATGGTTACACCATCGTCTATGACACATTTTCAATTTCCACCAATTAATTCTATATCAGGATACAATCCGTTAACTCTACCTCCGATTACAATTTCTTCGACATCATTACCATGTTCTTCGCCTGTGTCGACACCAGCATCATCAAATCAGCCATCTGCTATCATTCATGGTGGTAAAATTATTCCTTTCGTACCCGGAATTCCAGGGCCAAATACAAATTCATCATCGAATTTACTTCTACAGCAACAACATGCTCTGAATAACGTACGAGTGATAAGTCCAAATAGATTGAAGAACATCCCGAGCCCTTTAACGTACACGCATGCCTCGAATAATTCTATGCTGTCTGGAACATCAGTACTTCGGATTAATACCGGCCTGTCCAATACAAATATACCAAATAACGCAATGTCACCTCGCACCATACCGCACATCAAAATTTACGATGCTACCTCTACTACGAGCGAAGATTTAAAGCTGAATAAAAAACCACCGCACATGGTTGGAACTAAAAACGGGCTACTACTAACAACAGAAAAAAATGTGATTTGGTCGCCGGCAAAACAAGAACTTCAGGCAGCCGCGGCTTCTAATACTTCTAAAAGATTTAATTTTGCCAGAATGGCGGAAAATTTGAGTCCACGGAAACTGAATACAACATTGCCTCCCGGACGATCACCGGATGCCGAAATTCGTCATTTTAATTATGAAAATTTAATTTCAAAATCAGCTATTTTGATTAAACCTCCTCCGCCACCATCTAGTCAACATAATGAGACATCACCGCGTCCTGCAGCTATAACACCAATTCATATCGATGTCGATCCTATAACACCACCATCGCGATCACCACAACTACCTGTAAAAAATAAATTTCTGCGGCCAACATCTCTTCCCTTGAAGCCCGGCACTTTTATACAAAAGAAACATCATGGAATCACCCCAACGCACAATACTATGCCACTTATTTCACCGGAAACTCCGAGACCATCAAAAAATTGTATCCAGCTTTATTTAAATGGACACGCATATACATATCTTGGCCTGAAATGTAGTACAAAATTGACATATTGCACGTTAAATCGAGCGCAACCCGTTTACATTGCAAACCAACATAAATTGTCCATGTATAGTGAATGGCGGGTGCAAACCGATTATGATCCCCATCCATTAGGTTTGAAGCAAGACAAAGCAATTTCGTTGTACGATTCGAGACATCGGCCGCACACTTATTCGATCGCAAAAGATAAAACTCGGCTGGCATCGCAAAATACATTTTTGGTGCATTCCCAATCTACAATTATGACTCCGTTTGAAAGCGCGATGCCCACCCCTAAAGATGGCCAATACCCGCATCATCAAGTTATGCAAATTGAAGTTCCACCACCACCACCACAACAAGCAGTTCTTCATTGTGAAACAACAAATCTGTATAGTACAACGGCGACGGGGCCTATTTCGTCGTCGACTTCATCGTCGGCTGTGGGGGCGATACCTGGTGGTTACGAGAGTAATGAAGATTATACGTATGTGCGAGGACGAGGGCGAGGTCGTTATGTCTGTTCCGAATGTGGCATACGTTGCAAAAAACCGTCAATGCTTAAGAAGCACATTCGAACGCATACTGATGTACGGCCATACACTTGTAAAATGTGCGCGTTTAGTTTCAAGACCAAGGGAAATCTGACAAAGCACATGAAATCGAAGACGCATTATAAAAAATGTATAGAATTAGGGTTGAATCCGATTCCGATGCCGGGTATGGGTATGGATGATGATTCAAATGAGATGTTGGATGATCAAATGTCGATGACCGGAAGCGGTCGTACTAGTACCATTCCTGGAGACTCGGACACAGATTCGGAGAGTGATGGGGACGATGTCGAAAGTGAAAGTAGTGATACCGATGAATCGAAATCTCGTCTACTCGAACAGGAAGCTGCACACTGTTTAATTTCGCTATCTATGACTCCACCTATGCCATCGGTAAGCACAACAAATTCCTACATTCAACCTTCAATTGATCCAGCGGAAAATCGGCAACGTTGTATTATTACAACATTTTCTTCAGCCAAGCCAAGCGAATTCAATCTTCTAAAACACGATCAATACTATTCAAATCCTAAAGTGAATAAAACGTTCAATGTAGTACGAAATGCGCCACCAGAAGTTGTATCAAGTGATATATCCTCATCAGCCACCGATGATTCAATGCCTATTGATTTAACAAAACCAAAAGAACGGGAAAGGCCGGCTTTATATGGCAATCCTCATAGTTTAGTGCAACAAGTACCGGCTCAGGCACGTCAACCAATATCAGAAGTAATCGGCCCAATCGATCAAACTCGCTTTATCACATCGTTAGTGTCAATAATGGAGAAAATACCTACTTCAACCAGTAATAGTGATAGTAATAACTTACCCAGCCATATAGATGAGAATAAGTTGCTGCATCAATATTTGACGGAGCGGGCTCTCCAAGATTCTAAAATGAAACAGTCCCAGATGATAAAAAAATTAAATAATATCGAGAATTGCGAGACGAACACAAATAGCAGCGATGGTGTAATCGGTGGTAATGGGATCATTATATTAAGCCAGCCGTCTACACCGCTGGCCTCGACACCAACTAATTCAGAGTGTTTCGGTGCTAAATATGATGAGAAAATAATAGAAAATGAAAGTGAGAAACAATCGAATCACAGTGAAACCGAAAAAGAGCTGGGAAATGCTTCGAGTATGGAGACCTTAGCTGAGATTGCAGCAAGTTCTGTTAAACTAGATGTGTCCGCAAATCAAAAAATGTTGAACATAAATGATAATGCGAAAACTGTGGCATCTGAATATTTAAAACTGGCATCGAATGAAACAAGGCGGCAAGCAAAGATATCGATCAACGAAGATGACGAGTTTAACAACAGTGAATCAGATCAGGATGATTTATCGAATAAACTTTCGAATACGAATCTTGTGCGTAAAGTGGTAGTCGGTGAAGATGGTTTTAAGAATCCGGTCGCTGAAAATACACAAGTTCCCTATACACCACGGCTTCTCGAGGATGGTCGCGTTGTTTGCACGGTTTGCTCGAAAACGTTTCAAAAGGAATATCATTTATTATTGCACTATAATATTCACTATATCGAACGTAAATTCCGTTGCGAACCGTGTGCGATTAGTTTCCGTACCAAAGGCCATCTCCAAAAACATGAACGAAGTGTTCAACATAATACCAAAGTTTCAATGACGTCAACATTTGGTGTGGCAACCACATCAAATCCGCGTCCATTTAAATGTGGTGATTGTAAGGTTGCGTTTCGTATACATGGGCACTTGGCAAAGCATTTACGATCAAAAAGTCATGTCATGAAATTGGAATGTATTGGAAAATTACCGTTTGGTATGTACGCGGAAATTGAACGGGCCGGTGTTAGTTTAACCGATATTGATACAACAGACTGTGATAACTCATTGACAAGTTTATTGTTGCTTGCCCAAAAATTACACGAGAAAGATCCGAATATATTTGGTAACTGGAGTCCAGATGCGAATAATATTTCGATTTTGCAGCAGCAGCAACAGCAGCAGCATATTAGTAATAAGAATAATAATAGTAATAATGATACAGATAGTGATGATAGTGATAACCAAATTGATGAACAAAAAGATGAAATTAATAGTCTTAGCCGTAATATGGGTAATACCAGTAATATTGTTGGTGGTGGATTGATAAATATTAGTAATAATATTGGTAATAGTAATTCTATAAGTGGTGGAAATGGTGGAGGTGGTGGTGATTCAGCATTTTCATCAGACTCGAGTACTGGTTCAATTAAACGTAAAATAGACCAAATAACCGGAAGTCTAGATCCTCTACTTATAGGCAGCGATGAGCAAGCGCCATCACCATCATCCTCATCATCTATAAATATCGATCATAAAAGACTTAAAACACTAAGTGACATCTAG
Protein Sequence: MDDSPAYLISYSRFEYAEICTKINHCSSLKIRQKYHDSDDRGDKSAAPLIDIVQKNSSNNNNNEIDERHNRRDEDLLKSHHIHNQHQPIRELPKFVNNNNSSATFDDRKYLHKKFKRLASTTLNDIHLENNGLVNNSNLIVNNNSNSNISPPLSSFTSTSSQSPPSVVPTAITTTTTIAPTTTLISPPNLHHIQHQKHQHSEPGNCNPVQLMNSANNSTTSPKYNGHQENHHHIHNSSNINYNELRYNDSITVSGQIVTTQQPHIVQTGGNNVIYVSLRPSNLVQQQLPPSQSPSILSQQTNYVKEEEESSSIDDISSSGMGINESYTHQNHYQPQHLPNGILAQGNSSTTTTLISAPKLISSMPSTVPSSGATSATAPSSTNGRHVCPYCQMNCSKPSVLQKHIRAHTNERPYPCGPCGCAFKTKSNLYKHQRSRTHTLRTQGGEPAEDDVSQGSDQEQDQDQQFNQFDSLTHPQNPSMEVVEMKYSSQQYIHQQPLPNHQPQQQPIQEQKPYKPKFHQINAYKPYGDQGNSNSSSCSGTVKDEPKQQSHIIATTSISFIANSSVMIKPQVPNVVSTPPKNLDFASHITKLISDNEAIVEGGKPPLPKKTLKTSFRGTIPENSSPKLALALLHKEINANAAGQTSNNKLIVSNSRYVNFPTSINNPGTSSQADTIAGPSLTQPLNLSKVVVKNVPNHPQNPERSIIKDLLLNTKEFGAVDGMEAAESLYHCPFCKISFRNAETLKYHTICYCQGNQANSPHNSASASPAASPSHQYMRTHSNSESYNPNSLAKLASTSLRQHPYRTPTKLFNLAKANIKPTRPRLENIVINEKQDEIVNRNIDIVQAPLPSPGPLLGNTRLVDSYYKTPSDRGLMEEKTQGVSLYIVQTNQERSPSPMETQSHNFALPTMISDDPAISHRRNSNSVNNFQMFGGEVQVIEKKNDLFPTYGAGGSVTSLSPSDSEPSPILVRTGLFSGGSLQLPQTPKEKINRTPLTPKLLGTPAMVTPSSMTHFQFPPINSISGYNPLTLPPITISSTSLPCSSPVSTPASSNQPSAIIHGGKIIPFVPGIPGPNTNSSSNLLLQQQHALNNVRVISPNRLKNIPSPLTYTHASNNSMLSGTSVLRINTGLSNTNIPNNAMSPRTIPHIKIYDATSTTSEDLKLNKKPPHMVGTKNGLLLTTEKNVIWSPAKQELQAAAASNTSKRFNFARMAENLSPRKLNTTLPPGRSPDAEIRHFNYENLISKSAILIKPPPPPSSQHNETSPRPAAITPIHIDVDPITPPSRSPQLPVKNKFLRPTSLPLKPGTFIQKKHHGITPTHNTMPLISPETPRPSKNCIQLYLNGHAYTYLGLKCSTKLTYCTLNRAQPVYIANQHKLSMYSEWRVQTDYDPHPLGLKQDKAISLYDSRHRPHTYSIAKDKTRLASQNTFLVHSQSTIMTPFESAMPTPKDGQYPHHQVMQIEVPPPPPQQAVLHCETTNLYSTTATGPISSSTSSSAVGAIPGGYESNEDYTYVRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPYTCKMCAFSFKTKGNLTKHMKSKTHYKKCIELGLNPIPMPGMGMDDDSNEMLDDQMSMTGSGRTSTIPGDSDTDSESDGDDVESESSDTDESKSRLLEQEAAHCLISLSMTPPMPSVSTTNSYIQPSIDPAENRQRCIITTFSSAKPSEFNLLKHDQYYSNPKVNKTFNVVRNAPPEVVSSDISSSATDDSMPIDLTKPKERERPALYGNPHSLVQQVPAQARQPISEVIGPIDQTRFITSLVSIMEKIPTSTSNSDSNNLPSHIDENKLLHQYLTERALQDSKMKQSQMIKKLNNIENCETNTNSSDGVIGGNGIIILSQPSTPLASTPTNSECFGAKYDEKIIENESEKQSNHSETEKELGNASSMETLAEIAASSVKLDVSANQKMLNINDNAKTVASEYLKLASNETRRQAKISINEDDEFNNSESDQDDLSNKLSNTNLVRKVVVGEDGFKNPVAENTQVPYTPRLLEDGRVVCTVCSKTFQKEYHLLLHYNIHYIERKFRCEPCAISFRTKGHLQKHERSVQHNTKVSMTSTFGVATTSNPRPFKCGDCKVAFRIHGHLAKHLRSKSHVMKLECIGKLPFGMYAEIERAGVSLTDIDTTDCDNSLTSLLLLAQKLHEKDPNIFGNWSPDANNISILQQQQQQQHISNKNNNSNNDTDSDDSDNQIDEQKDEINSLSRNMGNTSNIVGGGLINISNNIGNSNSISGGNGGGGGDSAFSSDSSTGSIKRKIDQITGSLDPLLIGSDEQAPSPSSSSSINIDHKRLKTLSDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01456847;
90% Identity: iTF_01054796; iTF_01052693;
80% Identity: -