Nfla017577.1
Basic Information
- Insect
- Nephrotoma flavescens
- Gene Symbol
- -
- Assembly
- GCA_932525705.1
- Location
- CAKOBH010000585.1:162742-164875[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.2 37 6.8 3.0 1 23 337 359 337 359 0.98 2 11 0.017 3 10.2 0.3 1 21 365 385 365 386 0.93 3 11 7e-05 0.013 17.7 1.1 1 23 393 415 393 415 0.91 4 11 0.00066 0.12 14.6 2.7 2 20 422 440 421 442 0.93 5 11 0.00045 0.082 15.1 0.6 3 23 450 471 449 471 0.95 6 11 0.0091 1.6 11.0 0.2 2 23 491 513 490 513 0.94 7 11 0.00047 0.084 15.1 3.7 1 23 519 541 519 541 0.98 8 11 1.2e-05 0.0022 20.1 0.6 1 23 560 582 560 582 0.98 9 11 2.6e-06 0.00046 22.2 1.0 1 23 588 611 588 611 0.96 10 11 6.6e-05 0.012 17.7 0.2 1 23 619 641 619 641 0.95 11 11 0.081 15 8.0 6.3 1 23 647 670 647 670 0.96
Sequence Information
- Coding Sequence
- ATGCAAAAACATTTAGCGAGTGGGGTATTGTGTGCCGTGCCAACCTGTAAGTCGTCTAGACGAACACATCCAACGAGAAAGTTCTATAGTTTTCCTTTGGATAAACAATTATTCGAGATTTGGTTAGAAAAGTGCTCATTAAAGGAAGCAAAAAAATTACCAAAAATATTAGTAATTTGCGAAATACATTTTGACCCCATGGTTAAAGGGAAGACTAGATTGTTAAGAAATGCAGTTCCCATTTACTATCTCACATATCCGGACGTCAAAATTGATAATGAACCTCAATCAAATCAAATTGAAATTCCGGCAGATTCTTGCGATCCCTTTAGATCACAAACTATAACTGATATCATACCAATTATACCCGCGGAGCCTGGATGCAACAAAACTGCTGAATATATTCCAATACATTTGATAGATATTAATAGCGATGCATTGGAAAATACAAACGAAATAAACTCGTGTCCCGAAGAAATTCCATTATTGCGAGAAAAATATATCAAATCACTTTCATCGATAAAAATTTTAACAAATAAAATGAAGAAGTTCGATAAATTAATAAATTATTATAAGGATCATATTAATTTCTTGATGAGTGAAATTGAAAAGTACAAGATGAATGTTACGTTAAGCAAGCAGGTTgaatcattgccaaatttaagttcggcggcaaaggagtttggcttaacaattttaAATGATTCGACCAAAGACTGGCTTTGTAAAAAATGTAGAACTAATATAGATATGGCCTTAAAATCAAAAGAAACTGCCGATCTTGATATAATTAAATTGGAAAACAATATTATCAGTTCATGTTTTGAAACTAATGAAAAACAAATCAAATTCAGTGAAAATGTTCATATTGATAGCGCCAAACTTGCGAGTTTTCCTTCTGTACAATTAAAAGAGAGTTCGATAGATTTAAATTCAGTAGCGGCGAATTCTGAGCAAGATGAAAAAGAGCAAGTAGTAGCTGAACCGTTGTTGAGTGACGGTTTAAAATATGAATGTGAGAAGTGTGAAGAGAAACATGAAACTTATAGACAGTTAATCTATCATATGAGATTTCACGCAGATTTATACGTATATGAGTGTGAAAGATGTGGTAAAGAATTTCACATGGGTTCAAAGTACCGAGCTCATGCTCGTATATACGAAACTGAAAGATCATTTATATGTAATATTTGTCAAAAAGGATTTAAGCGACTGCACAATCTGATCCAACATGGGTACGCACACAAAACCAAGAAAATTCTTCCATGCCCGCATTGTGATAAAATTTTTTGTCACAGAAAGGGCTTATCCCAACACTTGAGCAACTACAGAGAAAAGCTTATATTATGTCCAATGTGTGATAAAAAATTTCTATATAATAGTCAGTTGAAAATACATATGGAGTTAAAGCATAATACAGGTATGCAGAAAAGTAAAAGAGTAAAATCCGATATTATCCGAAAACAAGTACCTTGCCGAATTTGCGCAAAATTATTCACTAACAAAAATGTTTTAGAAAGACACGTAAAATATGTACATAATCGGATAAGACCGTTTTCCTGCTCAGAGTGTGAAAAGAAATTTCCAACGTCCGGTTGTTTAAAACTTCATTTTCAACGTCACATTAATTCGAAAACAAGTTCACTAGATTCAGAAACTTTGAAGTCTTATCTGAAATATAAATGTAATGAGTGTGATAAAGCATATACAAGTCCGCTTTACTTAAAGAATCACAAAATAATTCATTCAGGTGCAAAAGATCATGTTTGTCCAGATTGTGGAAAGGGGTTTGCATTTAAGTGGTATTTAAAACGGCATAAGCGGTTAGTTCACGAAACGGCACACCCAAGCAATTTTTTATGTAATATTTGTGGTAAAGTATCAGCAAATGTACATGCTTTAAATGCGCACATGCTGAGCCATACAGGCGAAATGCCATTTCATTGCAAGTTTTGTGATTCAAAGTTCCGATACACAAAATCACTTCGGTTACATGTACGCAACAAACATTCCTAA
- Protein Sequence
- MQKHLASGVLCAVPTCKSSRRTHPTRKFYSFPLDKQLFEIWLEKCSLKEAKKLPKILVICEIHFDPMVKGKTRLLRNAVPIYYLTYPDVKIDNEPQSNQIEIPADSCDPFRSQTITDIIPIIPAEPGCNKTAEYIPIHLIDINSDALENTNEINSCPEEIPLLREKYIKSLSSIKILTNKMKKFDKLINYYKDHINFLMSEIEKYKMNVTLSKQVESLPNLSSAAKEFGLTILNDSTKDWLCKKCRTNIDMALKSKETADLDIIKLENNIISSCFETNEKQIKFSENVHIDSAKLASFPSVQLKESSIDLNSVAANSEQDEKEQVVAEPLLSDGLKYECEKCEEKHETYRQLIYHMRFHADLYVYECERCGKEFHMGSKYRAHARIYETERSFICNICQKGFKRLHNLIQHGYAHKTKKILPCPHCDKIFCHRKGLSQHLSNYREKLILCPMCDKKFLYNSQLKIHMELKHNTGMQKSKRVKSDIIRKQVPCRICAKLFTNKNVLERHVKYVHNRIRPFSCSECEKKFPTSGCLKLHFQRHINSKTSSLDSETLKSYLKYKCNECDKAYTSPLYLKNHKIIHSGAKDHVCPDCGKGFAFKWYLKRHKRLVHETAHPSNFLCNICGKVSANVHALNAHMLSHTGEMPFHCKFCDSKFRYTKSLRLHVRNKHS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01052600;
- 90% Identity
- iTF_01053293;
- 80% Identity
- iTF_01053293;