Basic Information

Gene Symbol
-
Assembly
GCA_932525705.1
Location
CAKOBH010000029.1:827594-829555[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.0044 0.8 12.0 1.3 1 23 261 283 261 283 0.96
2 11 0.19 34 6.9 1.5 1 19 289 307 289 310 0.83
3 11 7.5e-06 0.0014 20.7 3.3 1 23 317 339 317 339 0.95
4 11 7.1e-05 0.013 17.6 2.3 2 23 346 368 345 368 0.93
5 11 0.0005 0.09 15.0 1.6 3 23 375 396 374 396 0.96
6 11 0.0033 0.6 12.4 0.0 1 23 420 443 420 443 0.96
7 11 6.5e-05 0.012 17.8 2.3 1 23 449 471 449 471 0.97
8 11 6.3e-06 0.0011 20.9 2.1 1 23 490 512 490 512 0.96
9 11 5.3e-07 9.6e-05 24.3 3.7 1 23 518 541 518 541 0.96
10 11 0.011 2.1 10.7 3.1 1 23 549 571 549 571 0.97
11 11 0.015 2.8 10.3 2.3 1 23 577 600 577 600 0.95

Sequence Information

Coding Sequence
ATGAAATGTAAAATAAAATGTGCTGTAGAATCCTGTAGAGCTACCAAGATCACACATCCAAATAGAAGATTTTTTATGTTCCCGCAAGATGAAACTCTTCTGGAAATATGGAGGGAGAAATGTAGTCTTTCGAAATCCAGGCCATTAAAAAGTTTAAAGCTTTGCCAAGTTCATTTTGATAGTAAAAATATTGGAATTAGAAAATTAGCTATGGGTTCCGTCCCAGAATATTATTTAACAGATCCGAACATAAAAATTGTTAATGTATTCAAGAAAACCGGAATGTCCTTTAAAAACTATGAGGTAAATGTTAGTAAAAAGATAGGTCGTTTGACCACATTAATCCAATTTTACAAGAAAGAGAACAACATTCTCAAAAGTGTTATTAAAAAGCACCGACTAGTTAATTCGACAAAACCTCACATTAGTAAACTTCCTAATTTAAACTTGTTGGCGAAAGAGTTTGGTCGTGTGTTCTTAAATGATTCGTTGAAAGAATGGCCATGTGCTAAATGTATGGAGACAATAAAAGACGACCAGAACGTAAAAGAAGAAAAATTTACCCCAGACTTGTTAAAATTGAAACAAAACGATGATGAAGAACGAAAATCAAACATTGCAATAAGCGACGATATAAGTCTAGTTTCCGAAGAGGAAGACGAAATCTCTCCTGATGAGAGATCCTGGGGGAGTGCAAGCGACAAGGAATCAGTAAACATCAAGAATGAAAATGCAGAGCAGGAAGTAATTGACGGTTTTTTAGCTGTTACCCTTGAAACGTATGAATGTGAAAAATGTAACGTAAAATTAAATTCGTATAAACAGTTAATAAGGCATTTAAGTTTTCATCGAGATGCATACTTATACGAATGCGAAAGATGTGGAAAAGAGTTCCATCAAGGTTGTATGTACCGTGATCATTCTCTTGTTTATCAACTCGAAAGACCCCATGTATGCAAGATTTGTGGAAAAGATTTTAAAACTCCTAAGTATCTAAAACGACATGAATTCAGACATATTACAGAAAGAACCGTGCCTTGCCCCCTTTGTGGAAAAATGTTTAGTCATAAGCAGGCTTTACACAATCACTATTTTAGTACCCACAAAGAGAAACGTAAGGCCTGTACTCTGTGCGATGCAACATTTAAATTAAAAGTTTCACTTAAACATCATATGAGTAAAGTACACGGAGCTTCAGAATCTGGCAAGACTACTACTAGTACTAAGAAAACTGTGAAATCCGAAAGAACGCTCGAGTTTGCTTGTGAAATATGTGGAAAGTTAGTAACAACCGAGCTCGGTTTAAATTTACATATAAGAAATATACATAAAAAGGATAGACCATTTCCGTGTTCATATTGTAGTAAAACTTTTATCAGCGTTCAATTCTTAAAACGCCACATGCAGTTTCATATTAATAAAAAGAATAGTCCCGTCGATTCTAAAACGAAAGATGCATTTTTGCAGTTTAAATGTGATGAATGCGATAAATCGTTCACAGATTCACGATTTTTAAAGCAACACAAGATATTGCATTCCGGTTTGAAAGAACATACTTGTGAACATTGTGGGAAATCATTTGCATTAAAATCATATTTAAAGCGTCATATACGTTTAATCCACGAAATAAATCATCCGAATAATTTTGCCTGTAGTAAATGTGGCAAAGTATCCAGAGATGTATCACACCATAATTCTCATATGCTATCACATACAGGCGAAACTCCATTTGCTTGTGAATTTTGTGTTTCGAAATTTCGTTACAAAAAATCACTTCAATTGCATATCAAGAACAAACATTCCGAAACTGTTTAA
Protein Sequence
MKCKIKCAVESCRATKITHPNRRFFMFPQDETLLEIWREKCSLSKSRPLKSLKLCQVHFDSKNIGIRKLAMGSVPEYYLTDPNIKIVNVFKKTGMSFKNYEVNVSKKIGRLTTLIQFYKKENNILKSVIKKHRLVNSTKPHISKLPNLNLLAKEFGRVFLNDSLKEWPCAKCMETIKDDQNVKEEKFTPDLLKLKQNDDEERKSNIAISDDISLVSEEEDEISPDERSWGSASDKESVNIKNENAEQEVIDGFLAVTLETYECEKCNVKLNSYKQLIRHLSFHRDAYLYECERCGKEFHQGCMYRDHSLVYQLERPHVCKICGKDFKTPKYLKRHEFRHITERTVPCPLCGKMFSHKQALHNHYFSTHKEKRKACTLCDATFKLKVSLKHHMSKVHGASESGKTTTSTKKTVKSERTLEFACEICGKLVTTELGLNLHIRNIHKKDRPFPCSYCSKTFISVQFLKRHMQFHINKKNSPVDSKTKDAFLQFKCDECDKSFTDSRFLKQHKILHSGLKEHTCEHCGKSFALKSYLKRHIRLIHEINHPNNFACSKCGKVSRDVSHHNSHMLSHTGETPFACEFCVSKFRYKKSLQLHIKNKHSETV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01052618;
90% Identity
iTF_01053402;
80% Identity
iTF_01053402;