Nfla001136.1
Basic Information
- Insect
- Nephrotoma flavescens
- Gene Symbol
- -
- Assembly
- GCA_932525705.1
- Location
- CAKOBH010000029.1:812524-814368[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.011 1.9 10.8 2.2 1 23 226 248 226 248 0.98 2 11 0.00019 0.035 16.3 0.7 1 21 254 274 254 275 0.95 3 11 6e-07 0.00011 24.2 1.6 1 23 282 304 282 304 0.96 4 11 0.008 1.4 11.2 5.4 2 19 311 328 310 333 0.91 5 11 8.2e-06 0.0015 20.6 0.3 2 23 337 359 337 359 0.96 6 11 0.0025 0.46 12.7 0.2 2 23 381 403 380 403 0.94 7 11 1.7 3e+02 3.9 5.9 1 23 409 431 409 431 0.96 8 11 0.00069 0.12 14.5 0.4 1 23 447 469 447 469 0.95 9 11 4.3e-05 0.0078 18.3 1.3 1 23 475 498 475 498 0.96 10 11 4.8e-06 0.00087 21.3 0.2 3 23 508 528 506 528 0.97 11 11 0.00031 0.056 15.6 1.5 1 23 534 557 534 557 0.96
Sequence Information
- Coding Sequence
- ATGAGTTTAAACGAGGATCAGACCTTAGAATTTGCAAGTAGTGAAGAAGTTTTGTACAGTCCAATTCCGGAATATTTGGACGACCCAAACGAACAAATTGAAGATGAACTCGGATTTCTTAGTTCTCCGATTAGTACGACAAGTAAAATAAACCGTTTGGTGGAAATGCTAAAATATTATAAAAACCATATAAGTTTCCTCGAGGATACAATTAGAAAGCACGAGATGAAAGAATCGTTACGCACGAAGATTGATTCATTCCCAAATTTAAGCTTGATAGCGAAAGAATTTGGTAAATTTTTTTTTAGCGATTCAGATGAAGAATGGTTATGTATAAAATGTATGGAAACTATAAAATTTGCTATTAACTCAAAGGAAATTCCAAAGCCACCTGCTATAATGAAATTGGAAATAAACCATATTGATGAGCCTTCATTATCAGACTTGGATTTAGATAATAAAAATTCCGCCACTGATTGGGAAATAAACTATATTGATGAGGAATTAAGTAATACAAATTTTGCCACTGATGATACTCAATTGAAGAATGAAGCAGAGGACAGTTCGAACAATTTAAACTCAGTTAGTACTAACAAGGAGAATGAGATAGAAAAATTAAATGAACTAGACCTGGAATTGTTAGAAGCAAAATTCTCTACCGCAGATGTAGGAAAGTACCATTGTGAAATATGCACGGCAACAAGTAACTCTTACCAAAAATTAATTTCACATTTAAGACGTCATCGAGGTGCACATATATACGAATGTGAAAGATGTGGTAAAGGATTTACTCACGGACACAATTACAAAGATCATATCCTTGTTTATCAAGACGAAAGACCACATATATGCGAAGTTTGTGGGAAAGGGTTTAAAACTCCAAAATACCTGAAACGACACCAGTTAAGCCACTTAACCGAAAGAATTATACCTTGTCCGCATTGTGATAGAATGTTTTGCCATCAAAAGGGATTACAGGAGCATTGTTTACAATTACACATTGAACGAACATGTCCTGATTGTAACGAAATATTTAAAAACAGTGTACTTTTAAGAAGGCATCTCTCTAGGATTCACAGCAAAAGTAAGAGAAGCAGGGCCAAGCTTCATAACGGAGAGAGTGGACCTTCGGAAAGGTTACCCTGTGGGCAATGTGAAAAGACATTTTTGACCAAAGCTAATTTAATACTACACTATAAAAATATTCATAAAAAGGAAAGGAAACATTCATGTCCGTGTTGCAGCAAATCATTTTTTACCACTCAAATTTTGCGAAGCCACATGCAATCTCATATAAATGAGAATGAAAGCAACGAAGTAATCGAAAAATATGCGAGATATAAATGTGACGAGTGTGATAGAACGTTTGCAGTTCTAGGCATGTATAGGGAACATAAAACGCTTCATTCCGGATTGAAAGAGCACAGTTGTCCATTTTGTGGAAAAGCATTTGCATTTAAAATTTATTTATCAAAACATGTTCGTTTAATGCACAATACTGCTGATCCAAAGAATTCTATATGTAGTTACTGTGGTAAAGTATCGGCAAATAAGGCAGCCCTTAAGTCACACATGCTAACACATACAGGGGAAACACCATTTTCTTGTACAATTTGTCCTTCTAAATTTCGATACGCGAAGTCACTTCGACTGCATATTAAAAACAAACATAATTCTGGAAATGTTTACACCCCAATTGCCATGGTCGCGTCACGTCAACTTTTGTGA
- Protein Sequence
- MSLNEDQTLEFASSEEVLYSPIPEYLDDPNEQIEDELGFLSSPISTTSKINRLVEMLKYYKNHISFLEDTIRKHEMKESLRTKIDSFPNLSLIAKEFGKFFFSDSDEEWLCIKCMETIKFAINSKEIPKPPAIMKLEINHIDEPSLSDLDLDNKNSATDWEINYIDEELSNTNFATDDTQLKNEAEDSSNNLNSVSTNKENEIEKLNELDLELLEAKFSTADVGKYHCEICTATSNSYQKLISHLRRHRGAHIYECERCGKGFTHGHNYKDHILVYQDERPHICEVCGKGFKTPKYLKRHQLSHLTERIIPCPHCDRMFCHQKGLQEHCLQLHIERTCPDCNEIFKNSVLLRRHLSRIHSKSKRSRAKLHNGESGPSERLPCGQCEKTFLTKANLILHYKNIHKKERKHSCPCCSKSFFTTQILRSHMQSHINENESNEVIEKYARYKCDECDRTFAVLGMYREHKTLHSGLKEHSCPFCGKAFAFKIYLSKHVRLMHNTADPKNSICSYCGKVSANKAALKSHMLTHTGETPFSCTICPSKFRYAKSLRLHIKNKHNSGNVYTPIAMVASRQLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01052527;
- 90% Identity
- -
- 80% Identity
- -