Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371225.1:221365142-221366724[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.19 43 6.9 2.0 2 23 203 225 202 225 0.96

2 10 1.5 3.3e+02 4.1 2.1 6 23 234 251 234 251 0.99

3 10 0.00029 0.064 15.8 3.6 1 23 257 279 257 279 0.99

4 10 5.5e-06 0.0012 21.2 1.7 1 23 287 309 287 309 0.98

5 10 2.3e-05 0.005 19.3 0.2 1 23 317 340 317 340 0.95

6 10 0.00029 0.064 15.8 1.3 1 23 346 369 346 369 0.96

7 10 0.063 14 8.5 3.0 2 23 378 399 377 399 0.97

8 10 2.7e-05 0.0059 19.1 0.3 1 23 406 429 406 429 0.97

9 10 1.1e-05 0.0024 20.3 0.6 1 23 435 457 435 457 0.98

10 10 1.3e-06 0.00029 23.2 4.3 1 23 463 486 463 486 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.19	43	6.9	2.0	2	23	203	225	202	225	0.96
2	10	1.5	3.3e+02	4.1	2.1	6	23	234	251	234	251	0.99
3	10	0.00029	0.064	15.8	3.6	1	23	257	279	257	279	0.99
4	10	5.5e-06	0.0012	21.2	1.7	1	23	287	309	287	309	0.98
5	10	2.3e-05	0.005	19.3	0.2	1	23	317	340	317	340	0.95
6	10	0.00029	0.064	15.8	1.3	1	23	346	369	346	369	0.96
7	10	0.063	14	8.5	3.0	2	23	378	399	377	399	0.97
8	10	2.7e-05	0.0059	19.1	0.3	1	23	406	429	406	429	0.97
9	10	1.1e-05	0.0024	20.3	0.6	1	23	435	457	435	457	0.98
10	10	1.3e-06	0.00029	23.2	4.3	1	23	463	486	463	486	0.98

Sequence Information

Coding Sequence: ATGGAAAATCAAAACTGTGGTCTGTGCTTAAAGCCAGCCGAGGACAAACCCAATATCGGTGTATTTGGCGAGCAAGGCATACAATTAGGCGTTGCATCGATTTTGTCGCATCATTTCTGGTTCGAAATGAAGGAAAATGAAGACAGCCCCCAAAGTATTTGTACAGCATGTTGGCTCAATGTCCATAATTTTCACATATTCTATATGCAAATATACAATGCTCACCACAAATTGGTCGAAAAATTGGATATTAAAGAAATAAAAGTTGAAGAGCCAATCAATGAAATAATCAGTGAAAATACGATTATGAATACCTATATCGAAATAATGCCGGAAAAAATCGAAGATGCTGAAGAACATACCATTCACGGAGATCACTTTGCAGATGATAGCACAGAAGACATCAAAAGTAATCATTGCGATTCTGCAACGAACGACAATGAAATGGAAGTGCTACTTATTGATGAACCAAAAAGTTCAGACGCAGTGTCAAATTTGCAAGAGAAACGCAAGAAGAATTTTAAACGTACAAAAACAAAAAGGAATAACGAAGAAACTCGTCAGATTGAACGCGAAGATCAACAAATTCGTGAATACTTTGCAATGGAATGTAAACTGTGTTCAACAAAATTTCAAATTTTCCAAAACGTTAAATCGCATTATCGCACTTCTCACAACACGAACGGATATTTAATGTGTTGTGGCCGAAAATTTTTCAAGCGATGTTACGTTCTTCAGCACATCCAGCGACACTTGAACCCTGATATATTTAAATGTCACGTCTGCAATAAAACCTACTTGGAAAAACGAGGCCTTCAGAATCACATGAACACGCATTTACCCGTTACTGAGAAACCGTTTAAATGCAATAAATGCCCTAAAGCATTTGCCAAAAATTTCCTTTTAAAACAGCACCAAATTCGCCATGTATCCGACGATGAGAAACGATTCATTTGCTCTGATTGTGGAAAATCGTTTGCTTCTAATTCTATACTCCAGTCACATAAGAGAGGGGTACACGAAGGTGCCTATGTCCATATATGTGAAATATGTGCGAAATCGTTTAAAAGTAAATTATTTTATGAAGCACACATGAAATCGATTCATAGTAATGAAACTATTCCAAAAGTTCAGTGCCAACTGTGCGGCACGTGGTTGAAACATGAGCACAGTTTGAGAAGTCATATGTTGCGACATGCAGACGCGAATAAAAATTACACTTGTAAAATTTGCGGTAAACAATCACCAAATCGTGGAGCTCTACGTAGCCACCAACAGTACGTACACTTGATTAGCCGAGCGCATAAATGCAGCATTTGCGATAAAGCGTTTAAGAAGGCTATTGGCCTTATGGAACACATGACAATCCACACGGGTGAGGTACTATATACTTGTCCGCATTGCCCCAAAACATTTAATTCCTCAGCCAATTTACATTCGCATCGCAAAAAAGTTCATCTGATCGAGTGGGAAGCAAATCGCAGGGCTAAGGTTATAAATTACAATGAAAAGAACGAATAG
Protein Sequence: MENQNCGLCLKPAEDKPNIGVFGEQGIQLGVASILSHHFWFEMKENEDSPQSICTACWLNVHNFHIFYMQIYNAHHKLVEKLDIKEIKVEEPINEIISENTIMNTYIEIMPEKIEDAEEHTIHGDHFADDSTEDIKSNHCDSATNDNEMEVLLIDEPKSSDAVSNLQEKRKKNFKRTKTKRNNEETRQIEREDQQIREYFAMECKLCSTKFQIFQNVKSHYRTSHNTNGYLMCCGRKFFKRCYVLQHIQRHLNPDIFKCHVCNKTYLEKRGLQNHMNTHLPVTEKPFKCNKCPKAFAKNFLLKQHQIRHVSDDEKRFICSDCGKSFASNSILQSHKRGVHEGAYVHICEICAKSFKSKLFYEAHMKSIHSNETIPKVQCQLCGTWLKHEHSLRSHMLRHADANKNYTCKICGKQSPNRGALRSHQQYVHLISRAHKCSICDKAFKKAIGLMEHMTIHTGEVLYTCPHCPKTFNSSANLHSHRKKVHLIEWEANRRAKVINYNEKNE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01054681;
90% Identity: iTF_01054681;
80% Identity: -