Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371224.1:121753811-121755950[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.22 48 6.8 3.0 1 23 337 359 337 359 0.98

2 11 0.049 11 8.8 0.2 1 19 365 383 365 386 0.90

3 11 0.00019 0.042 16.4 1.1 1 23 393 415 393 415 0.94

4 11 0.00017 0.038 16.5 4.1 2 20 422 440 421 442 0.93

5 11 0.0027 0.59 12.8 2.6 3 23 450 471 449 471 0.95

6 11 0.0035 0.77 12.4 2.3 2 23 491 513 490 513 0.94

7 11 5e-06 0.0011 21.4 1.8 1 23 519 541 519 541 0.98

8 11 1.3e-05 0.0028 20.1 0.6 1 23 560 582 560 582 0.98

9 11 2.7e-06 0.00061 22.2 1.0 1 23 588 611 588 611 0.96

10 11 7e-05 0.016 17.7 0.2 1 23 619 641 619 641 0.95

11 11 0.016 3.5 10.3 5.2 1 23 647 670 647 670 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.22	48	6.8	3.0	1	23	337	359	337	359	0.98
2	11	0.049	11	8.8	0.2	1	19	365	383	365	386	0.90
3	11	0.00019	0.042	16.4	1.1	1	23	393	415	393	415	0.94
4	11	0.00017	0.038	16.5	4.1	2	20	422	440	421	442	0.93
5	11	0.0027	0.59	12.8	2.6	3	23	450	471	449	471	0.95
6	11	0.0035	0.77	12.4	2.3	2	23	491	513	490	513	0.94
7	11	5e-06	0.0011	21.4	1.8	1	23	519	541	519	541	0.98
8	11	1.3e-05	0.0028	20.1	0.6	1	23	560	582	560	582	0.98
9	11	2.7e-06	0.00061	22.2	1.0	1	23	588	611	588	611	0.96
10	11	7e-05	0.016	17.7	0.2	1	23	619	641	619	641	0.95
11	11	0.016	3.5	10.3	5.2	1	23	647	670	647	670	0.96

Sequence Information

Coding Sequence: ATGCAAAAACATTTAGCGAGTGGGGTATTGTGTGCCGTGCCAACCTGTAAGTCGTCTAGACGAACACATCCAACGAGGAAGTTCTATAGTTTTCCCCTGGATAAACAATTATTCGAGGTTTTCTTGGAAAAGTGCTCATTAAAGGAAGCAAAAAAACTACCAAAAATATTAGTAATTTGCGAAATACATTTTGACCCCATGGTTAGAGGGAAGACTAGATTATTAAAAAATGCAGTTCCCATTTACTATCTCACATATCCGGACGTCAAAATTGATAATGAACCTCAATCAAATCAAATTCGAAGTCCGTCAGATTCTGGTGATCCCTTTAGATCACAAACTATAACTGATATCATACCAATTATACCCGCGGAGCCTGGATGCAGCAAAACTGCTGAATATATTCCGATACATTTGATAGATAATAGCGATGCATTGCAAAATACAAATGATACAAACTCGTTTCCCGAAGAAAATCGATTATTGCGTGAAAAATATATCAAATCACTTTCATCGATAAACATTTTAACAAATAAAATGAAGAAGTTCGAAAAAATAATAAATTATTATAAGGATCATATTAATTTTTTGATGAGTGAAATTGAAAAGTACAAGAATGTTACGCTAAGCAAGCAGGTTGAGTCATTGCCAAATTTAAGTTCAGCGGCGAAGGAGTTTGGCTTAACAATTTTAAATGATTCGACCAAAGACTGGCTTTGTAAAAATTGTAGAGCGAATATAGATATGGCCTTAAAATCAAAAGAAACTGTCGATCTAGATATAATTAAATTGGAAAACAATATTACTAGTTCATGTTTTGAAATTAATGAAGAACCAATCAACAAAGTCAGTGAAAATGTACATATTGATGATAGCGCGAAATGTGCCAGTTTTCCTTCTGAACAATTAAAAGAGAGTTCGATAGATTTAAATTCAGTAGTGACGAATTCTGATCATGATGAAAAAGCGCAAGTAGTAGCTGAACCGTTGTTGAGTGACGGTTTAAAATATGAATGTGAGAAGTGTGAAGAGAAACATGAAACTTATAGACAATTAATCTACCATATGAGATTTCATGCCGATTTATGCGTATATGAGTGTGAAAGATGTGGTAAAGAATTTCACATGGGTTCAACGTACCGATCTCATGCGATTATTTATAAAACTGAAAGATCATTTATATGTAATATTTGTCAAAAGGGATTTAAGACGCAGCGTGGTCTGTATCAACATAGGTATGCACACAAAACCAAGAAAATTCTTCCATGCCCGCATTGTGATAAAAGTTTTTGTCATAGAAAGAGCTTATCCCAACACTTGAGCAACTACAGAGAAAAGCTTATATTATGTCACATGTGTGATAAAAAATTTCTATATAATAGTCAGTTAAAAATGCATATGGAGTTAACACATAAGATAGGCATTCAGAACGATAAAAGAGTAAAATCCGATATTTTACGTGAACAAGTATCATGCCCAATTTGTGCAAAATTATTTACTAATAAACATTGTTTAAAAATACATGCAAAATATGTGCATAATCAGATAAGACCGTTTTCCTGTTCAGAGTGTGAAAAGAGCTTTTCAACGTCCAGTGGTTTAAAACTTCATTTTCAGCGTCACATTAATTCGAAAACAAGTTCATTAGATTCAGAAACTTTGAAGTCTTATCTGAAATATAAATGTAATGAGTGTGATAAAGCATATACAAGTCCGCTTTACTTGAAGAATCACAAGATAATTCATTCAGGTGCAAAAGATCATGTTTGCCCTGATTGTGGAAAAGGGTTTGCATTTAAGTGGTATTTAAAACGTCATAAGCGGTTAGTTCACGAAACGGCGCACCCAAGCAATTTTTTATGTAATATTTGTGGTAAAGTATCGGCAAATGTACATGCTTTAAATGCGCACATGCTGAGCCATACAGGGGAAATGCCATTTCATTGTAAGTTTTGTGATTCAAAATTCCGATACGCAAAATCACTTCGGTTACATGTACGCAACAAACATACGTAA
Protein Sequence: MQKHLASGVLCAVPTCKSSRRTHPTRKFYSFPLDKQLFEVFLEKCSLKEAKKLPKILVICEIHFDPMVRGKTRLLKNAVPIYYLTYPDVKIDNEPQSNQIRSPSDSGDPFRSQTITDIIPIIPAEPGCSKTAEYIPIHLIDNSDALQNTNDTNSFPEENRLLREKYIKSLSSINILTNKMKKFEKIINYYKDHINFLMSEIEKYKNVTLSKQVESLPNLSSAAKEFGLTILNDSTKDWLCKNCRANIDMALKSKETVDLDIIKLENNITSSCFEINEEPINKVSENVHIDDSAKCASFPSEQLKESSIDLNSVVTNSDHDEKAQVVAEPLLSDGLKYECEKCEEKHETYRQLIYHMRFHADLCVYECERCGKEFHMGSTYRSHAIIYKTERSFICNICQKGFKTQRGLYQHRYAHKTKKILPCPHCDKSFCHRKSLSQHLSNYREKLILCHMCDKKFLYNSQLKMHMELTHKIGIQNDKRVKSDILREQVSCPICAKLFTNKHCLKIHAKYVHNQIRPFSCSECEKSFSTSSGLKLHFQRHINSKTSSLDSETLKSYLKYKCNECDKAYTSPLYLKNHKIIHSGAKDHVCPDCGKGFAFKWYLKRHKRLVHETAHPSNFLCNICGKVSANVHALNAHMLSHTGEMPFHCKFCDSKFRYAKSLRLHVRNKHT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01052600;
90% Identity: iTF_01052103; iTF_01052600; iTF_01052081;
80% Identity: iTF_01052103;