Napp002595.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nephrotoma appendiculata
Gene Symbol
-
Assembly
GCA_947310385.1
Location
OX371223.1:47612577-47615696[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.052 12 8.7 2.4 3 23 292 312 291 312 0.96
2 11 0.69 1.5e+02 5.2 0.1 1 22 317 338 317 341 0.86
3 11 0.0076 1.7 11.3 1.2 2 23 434 456 433 456 0.94
4 11 5.1e-06 0.0011 21.3 3.2 1 23 462 484 462 484 0.97
5 11 3.7e-05 0.0082 18.6 3.5 1 23 490 512 490 512 0.98
6 11 3.5e-05 0.0078 18.7 2.1 1 23 518 540 518 540 0.98
7 11 1.3e-07 2.8e-05 26.4 2.1 1 23 546 568 546 568 0.99
8 11 0.00051 0.11 15.0 9.1 1 23 574 596 574 596 0.99
9 11 0.11 24 7.7 0.9 1 23 602 624 602 624 0.92
10 11 9.1e-06 0.002 20.5 0.9 1 23 630 652 630 652 0.97
11 11 5.3e-05 0.012 18.1 2.8 1 20 658 677 658 679 0.95

Sequence Information

Coding Sequence
ATGGCGAACGATTCAGCACAAATTTACAAAAATTTATACAATTCTGAAATATGTAGACTCTGTGGCGAAAATAATTCGAATGGAACCCCATTATACGACGAGACGGATGATGAAATTGATATTAAAACGCTAGTTAATCTTTATTTACCCGTAAAAGTCGCGGATGATGGAAAATATCCAAGACGCATTTGTCCTGGATGTCATCTGCAAGTGGAATCGACTGCTCAGTTTTTCGATTTGCTACTGTTGGGCCAAGAGAAATTACGTGCATTATTAAAACGTGAGATAGATGATCAGAAAAAGACACAAAAATCTCAGAGCTTATTGAAGTTTGATTGTAAAGAAGAGGAGGTAATCCCAAGTACTGAAGAGTATATGATTACAGAAGACAAACCGCTTTTTGGAGTTGATCACGATCTCTCAATGAAATGCGAAGGTATCGATAAACCTCGTCGAAAGAGAGGCCGCCCTCCACGTCCGCCACCCGAAGAACTCGAAGCGCAAAGATTAGAACAGATGGCTCAGTTAGAGGAAAAAATTAAAATCAAGCAAGAGGCTGAGAGCGATATTGAAGATGAAAATGGGCAGAGGAAGAAGAGACGTATAAAAATTCCATCACGATTCCAAGAGGTTGTACAAGGCAAAGAATTGGAAAAGATTCTTGCTGAGGAAGGTGTGATTGATAAGGTTGAATTTTCGGATGCGGATGAAATTGTTGACGATGGAATTCGTAAATTTGATGGTAATTTTAAAAATGAAATAATCGGTCATCTACAAGGAAATGATGGGATCAATATTGGTGATTTGGTGTTCATAAAATCGCCGAAACGTGGTCGTAAGAATTACAATCGGAAAGGTCGCACCAAATTGCTATGTGATATATGCAATAAAGAATTTTTCCACGAGTATCGGTTCATGAAACATCGCGCCTTGCATCGCAATGCTCGCTTCGAATGCATCGAATGTTTAGCTGAATTTCCGGAACAGAAACAGCTCACCGCACATCAGCAAATCACAAACCATAAAGGTGAAGGCGTTATCGAAAGCATGGATTTGATCCAAGAGCCATACAAACCACGGCATTACAACTCCAATAATAATGACGAAAATTATAGTGATGAAGGTGAAAGATCATATTCAACGACCTCGGCGACTATTGATGAATTTAACGTTTCGTTAAGGAGTGAGAAAGAAAATCATCCTTTACCTGAAAGTATTAAAAAAGAAATAAATAGTGAAGTCGCAATGCTCGACGATGGGCTAGATCAAAGTCTTAACGATAGCGTTCAGACAAAACTCCAGTGTGAAATCTGCTTAAGGGAATTTAATCATCAAGGCTCGCTGATGTACCACAAAGAGTCACAGCATAATAAAAACCGGAAATTCATTTGCAGTAAATGTGGAAAATCTTTCAGTCACCGGCTACTGTTGCAGCGCCATCAGAAAGCTCACTCTAATGATCGGCCTTTTGAATGTAATTTCTGCAGTGCCAAATTTAAATCCAAGTCGAACTTGAAGAATCATCGTCTAAAGCATAGTGGTGACAAGAATTATCCTTGTAGCATGTGCCAACAAAAGTTTGCGCACCGCAACAGTCTTATAACGCATATGCGATTACATAGCGGTGAAAAGCCGTTCAAATGCTTTGTGTGCGAGAAGAGATTCACGCAAAACGGAAATTTAACTGAGCACATGAGAACCCACACGGGTGAGCGACCTTTTAAATGTACCCATTGTGACCGCACGTTTACAACGAGTTCTCAGTGTAAAAGCCATATTAAAAAGCATATCGGGGATCGGCCATTTGCCTGTGAAATTTGTGATAAACGTTTCTTGTATTTAGAAATATATAAAACTCATCTTCGTCGACATAACGGCGAGAAACCGTTTTCATGTTCCATTTGCAAAAAAGGTTTTGCTGATAATTGGGGTCTTCGGAAACATCAACGATTCCATACCGGAGAGAAACCTTATCCATGTGAATTTTGTGGAAAACATTTTGCCGATTGTTCCAACTTGAAAAAACACAAAGCGAATAATTGTACGCTACGCTTTACAAACATACCATCTGAAAATACTGGACCATCGCATGCCAATAATGTGACTGAAGAAAACCCTTATGTCTGCAGACCAGAATCGCCTTCAGCCTCTGAAATGACTCCTGAACATATTGAGGAAATAATCCAAAACCCATCATCGCCACCACCCCTAGCGCTTGCCAGTTTTACAAATTCGCATGATAATTCCGACCCCATTGAATACAAACCGATTATCTATTTAACATATCAGTCAGCAATGGACGATACCATCGATCAATCGTGTAATGGTAATCAAATAAATTCAATATCAGAAATTGATCCGGTTACTGGAAATGAGATGGCCTTAGTTTCGCATAACGGGAACGATACTATTACAACCAATCAATATCTCAACGATACCATGTTAAATCACATGACCGAGGATGGTAGTTGTAATGATCCTATGATTATTACTGTGACGAAAGATGATTCTGATGAGAATGTTGATTGCATTACAACGGAAAATATTTTGCAATTGGCGGCACACAACGGGAGTGATTTGTTGTATCAAATACAGACGAATGATGGAATGATTGAGAATTATGGGGATAGTCAACAAATCGAATATATCATGGTAGAGGGTCGTCGATTGCGGTTAGTCAATTATGCGGATCCAATTGATTTAGAATCACCTTATATTTTAACTTAA
Protein Sequence
MANDSAQIYKNLYNSEICRLCGENNSNGTPLYDETDDEIDIKTLVNLYLPVKVADDGKYPRRICPGCHLQVESTAQFFDLLLLGQEKLRALLKREIDDQKKTQKSQSLLKFDCKEEEVIPSTEEYMITEDKPLFGVDHDLSMKCEGIDKPRRKRGRPPRPPPEELEAQRLEQMAQLEEKIKIKQEAESDIEDENGQRKKRRIKIPSRFQEVVQGKELEKILAEEGVIDKVEFSDADEIVDDGIRKFDGNFKNEIIGHLQGNDGINIGDLVFIKSPKRGRKNYNRKGRTKLLCDICNKEFFHEYRFMKHRALHRNARFECIECLAEFPEQKQLTAHQQITNHKGEGVIESMDLIQEPYKPRHYNSNNNDENYSDEGERSYSTTSATIDEFNVSLRSEKENHPLPESIKKEINSEVAMLDDGLDQSLNDSVQTKLQCEICLREFNHQGSLMYHKESQHNKNRKFICSKCGKSFSHRLLLQRHQKAHSNDRPFECNFCSAKFKSKSNLKNHRLKHSGDKNYPCSMCQQKFAHRNSLITHMRLHSGEKPFKCFVCEKRFTQNGNLTEHMRTHTGERPFKCTHCDRTFTTSSQCKSHIKKHIGDRPFACEICDKRFLYLEIYKTHLRRHNGEKPFSCSICKKGFADNWGLRKHQRFHTGEKPYPCEFCGKHFADCSNLKKHKANNCTLRFTNIPSENTGPSHANNVTEENPYVCRPESPSASEMTPEHIEEIIQNPSSPPPLALASFTNSHDNSDPIEYKPIIYLTYQSAMDDTIDQSCNGNQINSISEIDPVTGNEMALVSHNGNDTITTNQYLNDTMLNHMTEDGSCNDPMIITVTKDDSDENVDCITTENILQLAAHNGSDLLYQIQTNDGMIENYGDSQQIEYIMVEGRRLRLVNYADPIDLESPYILT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01460528;
90% Identity
iTF_01053716;
80% Identity
-