Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371225.1:1860584-1862476[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0075 1.7 11.4 3.3 3 23 252 273 250 273 0.95

2 10 4.8e-06 0.0011 21.4 4.7 1 23 277 299 277 299 0.97

3 10 4.9e-07 0.00011 24.5 1.8 1 23 305 328 305 328 0.98

4 10 0.00048 0.11 15.1 0.6 1 23 334 356 334 356 0.95

5 10 2.1e-05 0.0047 19.4 1.1 1 23 362 384 362 384 0.96

6 10 0.00045 0.1 15.2 2.6 1 23 408 430 408 430 0.98

7 10 2.2e-05 0.0049 19.3 1.9 1 23 436 458 436 458 0.97

8 10 0.00013 0.03 16.9 0.6 1 23 464 486 464 486 0.98

9 10 3.5e-05 0.0077 18.7 2.4 1 23 492 514 492 514 0.96

10 10 0.00024 0.052 16.1 4.5 1 23 520 542 520 542 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0075	1.7	11.4	3.3	3	23	252	273	250	273	0.95
2	10	4.8e-06	0.0011	21.4	4.7	1	23	277	299	277	299	0.97
3	10	4.9e-07	0.00011	24.5	1.8	1	23	305	328	305	328	0.98
4	10	0.00048	0.11	15.1	0.6	1	23	334	356	334	356	0.95
5	10	2.1e-05	0.0047	19.4	1.1	1	23	362	384	362	384	0.96
6	10	0.00045	0.1	15.2	2.6	1	23	408	430	408	430	0.98
7	10	2.2e-05	0.0049	19.3	1.9	1	23	436	458	436	458	0.97
8	10	0.00013	0.03	16.9	0.6	1	23	464	486	464	486	0.98
9	10	3.5e-05	0.0077	18.7	2.4	1	23	492	514	492	514	0.96
10	10	0.00024	0.052	16.1	4.5	1	23	520	542	520	542	0.98

Sequence Information

Coding Sequence: ATGACTAGCATTGATTTTGCTAATAAATTTGTATGTCGATTGTGCGAGAAGCAAAAAGATCTCGATAATTTATTTGATGAACGTTTGAAGAATGTTTTGAAGAAGCTCCGGGCATGCACAGATATCACGATCGAAAAACATGATACTCTTCCTAAATTTATTTGTAAATTGTGCCAAACAAATTTAGAATTTGCATATAAATTCAAAATTCAGTGTGAGTATACGGACCGTAAATGGAGAGATTTAATTCTTGAGCAACTCGAAATTAAAGAGATATCGAGTCCTGCATTAGTAGAACATATTGAACAAATTGAAGAATTGGAACATGAATCTATTTCTACTAAGGATGGAGCAGATGTTCGTTATGAAATTGAATATGTGAATGACATGATTACGATTAAGTATGAAGATGGCATTGAAACTAGTGACGATATTTATGTCGAAGATAGAGAGCAAAGAGATTACGACGACTTGATTGAACAGCTAGAGGATGATGACGGTCAGAGTGATGATGTTATCAATGTAAATAACGAAATTGACGAGCAGGTCAGAGTAGAATCTCCTCAATATCAAGACGAGAATATCGGAATTTCATATTATGAAGTTGAGGAATATGAAGATATTCAGAATTTAGATAATTCTGATGATTGTTCTAATCAAGTTCCTGACGATTCCAAAGGATCTGTTTCTCATGATCAAACTTTAGAGGTACAAATTGATCAGAATAGCGATGTTAATGTAACTGAACAGCATTGCGATTTGTGTGACGAAATTTTCCATTCTTCTGTCGAGCTAAATAAACACAAAAAGTCGTCACATAAAAAAATATTCCAGTGCAAAGAATGCAACAAACGTTTCTCAAAACGATATCACCTAAGGAACCATTTAGTAATCCACACAGGAGAAAATCGCTACAAATGCAATGATTGCGATAAAATTTATACAAATCACGGTAATTTAGATAGACATATTCGTGTGTTCCACAATAAAGAGAAAAAACACATTTGCGATACTTGTGGGAAAGGATTCTCTCAATTATCAATTTTACGACAGCATCGTGCTGTGCATTTAGAAGAAAGGCCATTTGAATGTGACGTTTGTAATAAAACTTATAAGACCCAGGACTATCTAAATTTACATAAGGAACTTCATAAACCACGAGAACAGCGTAAAATTAGAACTTATGTCAAGAAGCCGAGTAAAAAACCTCCGATTAAAATATTCGTTTGTCCATATTGTGGAAAGAAATCAAATAACTATTCGCTGCATCAaagtcacattcgcactcataccggggaaaaaccttacgaatgcaaaatttgtaataaaaagtttgcattccaacaatcgttgcgaagtcatcggcttcttcatactggtgaaaaacctttcaaatgcgaagcatgtggcttgacattccgccaaatcggacatttaaaaggccatcaacttatacatacaggtgaaaagaaacacgattgccttgtgtgtcataaaacgtttgcattgcgcggaaacttaactgttcatatgcggttacatacgggggaaacaccctacCACTGCAATCAATGTTCGAAGAAGTTTTATGATTCTAACGGCTTAAAACGGCACAAGATGGTGCACAGCAAACAACAAGCCAATGCAATTCAGTTATTGCAATCGGATGTCATTAAAATAGAGAACAATTCGGAATATGTTGGAAACGAACATGAAATATCGTATGAGGGTATTATAGAAAACGTAGACGAAATTGATACATCGTCCCCATCGCATTTACATTACGATTCTACTTCATATAACATTTTAAGTATTTCTTCGGAAAATTAG
Protein Sequence: MTSIDFANKFVCRLCEKQKDLDNLFDERLKNVLKKLRACTDITIEKHDTLPKFICKLCQTNLEFAYKFKIQCEYTDRKWRDLILEQLEIKEISSPALVEHIEQIEELEHESISTKDGADVRYEIEYVNDMITIKYEDGIETSDDIYVEDREQRDYDDLIEQLEDDDGQSDDVINVNNEIDEQVRVESPQYQDENIGISYYEVEEYEDIQNLDNSDDCSNQVPDDSKGSVSHDQTLEVQIDQNSDVNVTEQHCDLCDEIFHSSVELNKHKKSSHKKIFQCKECNKRFSKRYHLRNHLVIHTGENRYKCNDCDKIYTNHGNLDRHIRVFHNKEKKHICDTCGKGFSQLSILRQHRAVHLEERPFECDVCNKTYKTQDYLNLHKELHKPREQRKIRTYVKKPSKKPPIKIFVCPYCGKKSNNYSLHQSHIRTHTGEKPYECKICNKKFAFQQSLRSHRLLHTGEKPFKCEACGLTFRQIGHLKGHQLIHTGEKKHDCLVCHKTFALRGNLTVHMRLHTGETPYHCNQCSKKFYDSNGLKRHKMVHSKQQANAIQLLQSDVIKIENNSEYVGNEHEISYEGIIENVDEIDTSSPSHLHYDSTSYNILSISSEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01053703; iTF_01054649;
90% Identity: iTF_01054649;
80% Identity: -