Napp018229.1
Basic Information
- Insect
- Nephrotoma appendiculata
- Gene Symbol
- -
- Assembly
- GCA_947310385.1
- Location
- OX371223.1:265698532-265699893[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.00012 0.028 17.0 0.3 1 23 214 236 214 236 0.97 2 8 2.6e-05 0.0057 19.1 0.3 1 23 240 262 240 262 0.95 3 8 1.7e-05 0.0037 19.7 0.9 2 23 269 291 268 291 0.97 4 8 4.8e-05 0.011 18.3 0.3 1 23 297 319 297 319 0.95 5 8 0.00033 0.073 15.6 2.1 1 23 325 347 325 347 0.98 6 8 3.2e-06 0.0007 22.0 2.2 1 23 353 375 353 375 0.98 7 8 1.7e-07 3.7e-05 26.0 1.8 1 23 381 403 381 403 0.98 8 8 0.00023 0.051 16.1 0.0 1 23 409 431 409 431 0.96
Sequence Information
- Coding Sequence
- ATGTTGATGAATAATTATTTTGATTCTTATACGTGCCGAGCATGTTTAGAGTACACAGATGAAATGGTGCCTATCTTTGAAACTGATGAAGTAATGAGTAAACCAATTAAGCTGTCAACCCTCTTGTCTGAGTGCACCGGTGTTGAGCTGGTAGATGATGATGATTTTCCAAAACAAATATGTAATACATGCCTAAACGAGGCGACTCGCGCCTACTCATTTCGGGAGAAATTTCTTCGGGCTGATAAGTTCCTACGCGAAATGCTGGAGAATGCCACTAAAGAAGCTCAGAAAAATGCAGAAGTGGATTTTGTGGCTGTGCATATGTTAGATGAGGTAGCCAATGATGATGATGAACACCTAACTCCAATAGATGACATACCTGAAATTGAATTATGCGACGAAAATATAAAAACGGAGGAAAGTTTTACTGAACACGAGAATGACCTCGAATTTACGGTAATTGTGTCTGAACAAGATGCTGACCCGATCGAAGATAAAATTGTCCAGGAAAATCGACCTTTACGAATATACGTGAGGAAGAAGAAAAAGCCGAACGCGGATCAGGTAACGGAAGTGGATAAAGTTAAAACAGAACCAGTAAAAGTGCTTAAAAAGAAACCTACCGTTAAAAAATCGTATATATGCGAAGTGTGTGATAAACGGTTAAACAGTAAAAATGGACTGCAGGAACATTTGAAATTACATTTAAATCAATTTATCTGCGGAAAGTGTGGTCAAAAATTTAAAACGAACTCTGCGCTGGAAGACCACGAAGTCCGTCATGATCCGTACAACCCAAATAAATGTAAACAATGTGGCCGAATGTTTCGCACGGAAGAATTACTGGAGGAACACACAAAACGTGCGCATAAAGAAGAAAAGCCATTTCTTTGTGGTATTTGTGGCAAAGGATTTCTACAAAAAACGGCCTTTGAAAAGCACATGCGAATCCACACGGGTGAAAAACCATTTGAATGCGAAGTATGCCATAATCGATTTCGCTATAAAAATTCATTGGTACTTCATTTGCGAGGACACACGGACGAGAAACCATTTGAATGCTTGGAATGTAATCAAAAATTTCGAGACAAAGCACATCTACGAAAGCATTTGCTGGTTCATACAGGCGAAAAACCATTTACTTGTGAATTCTGTGAAAAAAGCTTTAATCGTAGCTCGAATCTTAATGCGCATCGTAAAATTCACACTGGAGATAGGAAATATATTTGTCCCGTGTGCAACAAAGCGTTTATTCAGAATAATGTTATGCAAGCACATTTGGCCAACCACAATAAGAAAATGTAA
- Protein Sequence
- MLMNNYFDSYTCRACLEYTDEMVPIFETDEVMSKPIKLSTLLSECTGVELVDDDDFPKQICNTCLNEATRAYSFREKFLRADKFLREMLENATKEAQKNAEVDFVAVHMLDEVANDDDEHLTPIDDIPEIELCDENIKTEESFTEHENDLEFTVIVSEQDADPIEDKIVQENRPLRIYVRKKKKPNADQVTEVDKVKTEPVKVLKKKPTVKKSYICEVCDKRLNSKNGLQEHLKLHLNQFICGKCGQKFKTNSALEDHEVRHDPYNPNKCKQCGRMFRTEELLEEHTKRAHKEEKPFLCGICGKGFLQKTAFEKHMRIHTGEKPFECEVCHNRFRYKNSLVLHLRGHTDEKPFECLECNQKFRDKAHLRKHLLVHTGEKPFTCEFCEKSFNRSSNLNAHRKIHTGDRKYICPVCNKAFIQNNVMQAHLANHNKKM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01054629; iTF_01053691;
- 90% Identity
- iTF_01054629;
- 80% Identity
- -