Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371225.1:248218131-248220349[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0021 0.46 13.1 3.9 1 23 184 206 184 206 0.97

2 11 1.9e-05 0.0042 19.6 1.5 1 23 212 234 212 234 0.98

3 11 0.0015 0.34 13.5 3.8 1 23 240 263 240 263 0.96

4 11 0.009 2 11.1 3.5 1 21 269 289 269 291 0.95

5 11 0.00019 0.042 16.4 1.9 1 23 297 319 297 319 0.99

6 11 3.8e-05 0.0084 18.6 1.2 1 23 325 347 325 347 0.98

7 11 0.0056 1.2 11.8 3.1 1 23 355 378 355 378 0.96

8 11 0.00077 0.17 14.5 1.1 2 23 385 406 384 406 0.97

9 11 0.00071 0.16 14.6 0.2 1 23 412 434 412 434 0.98

10 11 4.3e-06 0.00095 21.6 1.9 1 23 440 463 440 463 0.96

11 11 6.4e-07 0.00014 24.2 1.1 3 23 479 499 478 499 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0021	0.46	13.1	3.9	1	23	184	206	184	206	0.97
2	11	1.9e-05	0.0042	19.6	1.5	1	23	212	234	212	234	0.98
3	11	0.0015	0.34	13.5	3.8	1	23	240	263	240	263	0.96
4	11	0.009	2	11.1	3.5	1	21	269	289	269	291	0.95
5	11	0.00019	0.042	16.4	1.9	1	23	297	319	297	319	0.99
6	11	3.8e-05	0.0084	18.6	1.2	1	23	325	347	325	347	0.98
7	11	0.0056	1.2	11.8	3.1	1	23	355	378	355	378	0.96
8	11	0.00077	0.17	14.5	1.1	2	23	385	406	384	406	0.97
9	11	0.00071	0.16	14.6	0.2	1	23	412	434	412	434	0.98
10	11	4.3e-06	0.00095	21.6	1.9	1	23	440	463	440	463	0.96
11	11	6.4e-07	0.00014	24.2	1.1	3	23	479	499	478	499	0.99

Sequence Information

Coding Sequence: ATGTCAGCAAAATTGGCTGATGTTAAAATAAAGTTGGAAGGGAACGATTTAACATCCTATTTGGAAACGTTCAATAAAGAGATTGATGATGGTGAAACTATAACTGTGATTCAAGAAGCTGGATCTGAAAATGAGGAGGACGAAGAGGGTGGAACATATTTTGTTGATCAAACTGGAAACTACTACTATCAGGCGACAAAAGATTCAGATCCTGTGCTAACTGAACCGCCAAATGAAGAAGATGCACAATATGTTGAGGAATCCGATCCGCTTGACGGAAATCTGGTATATAACCAGAAAAAAGGTGATTATCAAAATGTCACATTGGTGCAATCGGGCACAAATTCAGAAGAAGTGAGTTACGTACTAATCATGGAGGGGAATCAAAAAAATAATGATGAAAATCAAGAGATAAATGTTTTTGATTTCGACGAGAATGATGAGACGCAAAGCGGTAAGACTCAGGCGATTGATTCGGGCCACGAAGATGATAAATCAAAAATCGTAAAACTTGTACCAAAGAAATCTACCCAAGTGTCAATAGCCCAGCACATGTGTAATTACTGTAATTACACAAGTCCGAAACGGTACTTGCTTTCCCGACATTTAAAATCACATTCAGAAGAAAGACCGCACAAGTGTTCGGTATGTGAACGTGGCTTTAAAACTTTAGCGTCGTTACAGAATCATGTGAATACGCATACTGGTACAAAACCGCATCACTGTAAATTTTGTGAGAGTGCATTCACAACGTCAGGGGAATTGGTGCGACATATTAGGTACCGACATACACACGAAAAACCACATAAATGTAATGAATGCGATTATGCGAGTGTTGAGCTCAGTAAATTGAAACGGCATATTCGATGTCACACAGGCGAACGTCCTTATCAATGCCCACATTGTACGTACGCATCACCCGATACGTTTAAACTTAAACGGCATTTACGAATTCATACCGGTGAAAAGCCATATGAGTGTGATGTGTGCCATGCGCGATTCACCCAATCGAATTCTTTAAAGGCACACAAATTGATACATAGCGTTGGCGATAAACCGGTATTCCACTGCGAACTGTGTCCAACAACGTGCGGCCGTAAAACCGATTTACGCATTCATGTACAAAAATTGCACACGTCAGACAAACCATTAAAATGCCGCCGTTGTGGTAATTCATTCCCGGATCGGTACAGCTATAAAATTCATGCAAAAACGCATGAAGGTGAAAAATGTTATAAATGTGACTTGTGTCCTTACGCGTCTATTTCAGCACGTCACTTAGAATCGCATTTGTTAATCCATACGGATCAGAAACCGTATCAGTGCGATACATGTGACCAATCATTCCGACAAAAGCAGCTACTGAAGCGCCACGTAAATTTATATCATAATCCGAATTATGTCCCGCCTGTACCCAAGGAGAAGACGCACGGTTGTCCAAATTGTAATCGGTCGTTTAGACATAAAGGGAATTTAATACGACATATGGCCGTCCATGATCCAAATTCGAATATAAAAGAGGAAGCGGTTGCTTTGAAATTGGGGCGACAGAGGCGTATTCGGATGATGGCTGCGAATGGTCTTAAGGTGGACGAAAGTTATGACGATGAAGATTTTGAGGAGGAAGAGGAGGATGAAGAAGACGAAGAGGATGAGCCTGAAAATGAGACGTCCCCAACTGAAAGTACTCCTGTGAGTCAAACTAATGTTGTATCGGTGAATGGCGAGGATGGCCAGCAGTATGTAGTACTGGAAGTTATTCAAATACAGGAAGGTGAAAATGACGAGGAAACTGATCAATTGGACGACGAGACGATGGAGGTGGATGAAGATTTTTTGATTGGTGATGGCATCGACGAGGAAGTTTTAAATGACATGCCAAGCCGTAGAATGCTAAAATCGGAAGGTAGAAAACTTATCGAAGATAATTTTGACTTTGAAGAACACGATGAAGATGACGTGGACCACCACAATGTGATCGACTTAGATGAGGATGACGAGCGGGAACACAAGGCCACAATAAAGCTACTACATATGCAAGAATAA
Protein Sequence: MSAKLADVKIKLEGNDLTSYLETFNKEIDDGETITVIQEAGSENEEDEEGGTYFVDQTGNYYYQATKDSDPVLTEPPNEEDAQYVEESDPLDGNLVYNQKKGDYQNVTLVQSGTNSEEVSYVLIMEGNQKNNDENQEINVFDFDENDETQSGKTQAIDSGHEDDKSKIVKLVPKKSTQVSIAQHMCNYCNYTSPKRYLLSRHLKSHSEERPHKCSVCERGFKTLASLQNHVNTHTGTKPHHCKFCESAFTTSGELVRHIRYRHTHEKPHKCNECDYASVELSKLKRHIRCHTGERPYQCPHCTYASPDTFKLKRHLRIHTGEKPYECDVCHARFTQSNSLKAHKLIHSVGDKPVFHCELCPTTCGRKTDLRIHVQKLHTSDKPLKCRRCGNSFPDRYSYKIHAKTHEGEKCYKCDLCPYASISARHLESHLLIHTDQKPYQCDTCDQSFRQKQLLKRHVNLYHNPNYVPPVPKEKTHGCPNCNRSFRHKGNLIRHMAVHDPNSNIKEEAVALKLGRQRRIRMMAANGLKVDESYDDEDFEEEEEDEEDEEDEPENETSPTESTPVSQTNVVSVNGEDGQQYVVLEVIQIQEGENDEETDQLDDETMEVDEDFLIGDGIDEEVLNDMPSRRMLKSEGRKLIEDNFDFEEHDEDDVDHHNVIDLDEDDEREHKATIKLLHMQE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01456709;
90% Identity: iTF_01053695;
80% Identity: -