Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371223.1:211142868-211144867[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 3.8e-06 0.00084 21.7 1.9 1 23 263 285 263 285 0.98

2 8 0.00036 0.079 15.5 1.0 3 23 293 313 291 313 0.96

3 8 8.9e-07 0.0002 23.7 3.3 1 23 319 341 319 341 0.99

4 8 6.4e-05 0.014 17.9 0.1 1 23 347 369 347 369 0.96

5 8 0.00042 0.093 15.3 1.9 1 23 375 397 375 397 0.98

6 8 1.9e-07 4.2e-05 25.8 2.8 1 23 403 425 403 425 0.98

7 8 1.6e-07 3.5e-05 26.1 2.6 1 23 431 453 431 453 0.98

8 8 0.00029 0.064 15.8 0.8 1 23 459 481 459 481 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	3.8e-06	0.00084	21.7	1.9	1	23	263	285	263	285	0.98
2	8	0.00036	0.079	15.5	1.0	3	23	293	313	291	313	0.96
3	8	8.9e-07	0.0002	23.7	3.3	1	23	319	341	319	341	0.99
4	8	6.4e-05	0.014	17.9	0.1	1	23	347	369	347	369	0.96
5	8	0.00042	0.093	15.3	1.9	1	23	375	397	375	397	0.98
6	8	1.9e-07	4.2e-05	25.8	2.8	1	23	403	425	403	425	0.98
7	8	1.6e-07	3.5e-05	26.1	2.6	1	23	431	453	431	453	0.98
8	8	0.00029	0.064	15.8	0.8	1	23	459	481	459	481	0.96

Sequence Information

Coding Sequence: ATGCTTAATGGTTCAACGATGAATGATAACGAGACGATCTGTCGTGCTTGTTTGGAAAATGCAGATAACATGAAATCTATATTTGAGACCGAAAATATTTTGAATAAACAAATAAGATTGTGTACCGTTCTTAATTATTGTACAAATTTAGATATATACGAGGGCGATGGCTTACCTCGTAAAATATGCCACAGCTGTGTCACAGAAGTTCTTAAGGCGTTTACATTTAAGCAACAGTTTATTCGGGCGAATACGATATTGCGCGATAAATTAGCAACTGTCACAATTGATGATGATGATAAAGATACCGCGAATTGTACGTTTGAACATGTGATAGTGAAGCAGGAATCGGACGATGAAAATGGCAAGGCAATAAATGAACTTGACCCCGCTGAAACTAAACCATTAGAGACCAAAATTGATTCTGATTCGGATGGTATACCAGACACATTTAACGATCATTTCGATGATGATCCGGATAGTGATGCAATGGAATCCTCTCGAGAAGATAAACAGCCGAAGCCACGTAAAAAACGGATTAACAATGATGATGAAGATGATGATGATGAAGAGGTAGATAAGGAATACCTAGAAAATTATTTCAAAGATCATGAATCCGATGATGAGTTTATGAAAAATAAAAAGGAAGAAATACGCGAAAAAATGAAAAAATTAACCGGTAATAATGAAAAATCTATCTTGACTGATCGAGCGTTACGTTCCTACTTGCGAGAACTAAAGAAACGGCCGAAAAATAAAAAGGAGGAGAAAGAAAAAACAACTACTTACAGCTGTAAAGTATGCAACAAGCAGTTAAGTAGTTCGAGCTCGCTTAAAACTCATATGTCGACTCACAACAAAGATAAGCAACATCTATGCAGTACTTGTGGTGAAGGTTTCCGCACGAAATCTGCCTATGACGATCATTTATTGACGCACAGTACAACTGATCCGTTCAAGTGCTCCAAGTGTAATAAAATATTTAAAAATAAACGTTCGTTACGTGATCACCTGCGAATTCATGTCGATGTGAAACCATATTTGTGCGGGGTGTGTGGCAAAGGTTTAACTCAAAAGGTTGCACTGAAGAAACATCTAATGATTCATACGGGAGAAAAACCATATGAATGTGATTTGTGCGGAAAAAAATTCCGTTACATGAACGTGTTAAAGCTGCATAAACGATACCATACAGGCGAGCGACCGTTCCCATGTAATGAATGTGGTAAACGATTCAAGGAGCGAACCCATTTACGGAAGCATATGATGATACATACAGGAGAGAAGCCATTTGAATGTGAATATTGTGGCAAACGGTTTAATACTAAAACATATCTAACGGCACATCGAAAAACTCATACCGGTGAAAGAAATCATTTTTGTGCAATTTGTGGTAAAGGATTTATTCAAAGAAACGTTATGCGAAACCACATGGCAACGCATCAACAACCAATGCCACCAATTGAACCATATGCTGTACCTATAATAATACCTGGTGTAACAGATATAAAAGAAACAAAATCTGATGATGAATCGCCATCTCAGCAATCTACATCACAAACGATAACAATTCAAGAAGCGCAACAACCAACATTATTACAACAACATGTAGTAGTCTCGCAACCACAACAAATAGTAGATCACCCAAACGCACACTTGGGGCAAATAGTAATACAACAACTTCCACCCGAAGAGGATACGTCAACGCAACAGACCGTACTACAATCTATGCATTCTCCACACATGCAAACGATACACAACACGATAATACAAACCCAGCAGCAGCAACAGCATCAAACATTGTACTACCAGTAA
Protein Sequence: MLNGSTMNDNETICRACLENADNMKSIFETENILNKQIRLCTVLNYCTNLDIYEGDGLPRKICHSCVTEVLKAFTFKQQFIRANTILRDKLATVTIDDDDKDTANCTFEHVIVKQESDDENGKAINELDPAETKPLETKIDSDSDGIPDTFNDHFDDDPDSDAMESSREDKQPKPRKKRINNDDEDDDDEEVDKEYLENYFKDHESDDEFMKNKKEEIREKMKKLTGNNEKSILTDRALRSYLRELKKRPKNKKEEKEKTTTYSCKVCNKQLSSSSSLKTHMSTHNKDKQHLCSTCGEGFRTKSAYDDHLLTHSTTDPFKCSKCNKIFKNKRSLRDHLRIHVDVKPYLCGVCGKGLTQKVALKKHLMIHTGEKPYECDLCGKKFRYMNVLKLHKRYHTGERPFPCNECGKRFKERTHLRKHMMIHTGEKPFECEYCGKRFNTKTYLTAHRKTHTGERNHFCAICGKGFIQRNVMRNHMATHQQPMPPIEPYAVPIIIPGVTDIKETKSDDESPSQQSTSQTITIQEAQQPTLLQQHVVVSQPQQIVDHPNAHLGQIVIQQLPPEEDTSTQQTVLQSMHSPHMQTIHNTIIQTQQQQQHQTLYYQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01054626;
90% Identity: iTF_01054626;
80% Identity: -