Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371223.1:149214507-149227076[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00034 0.076 15.6 3.4 1 23 227 249 227 249 0.98

2 11 0.0051 1.1 11.9 7.9 3 23 257 277 256 277 0.97

3 11 9e-05 0.02 17.4 6.5 1 23 283 305 283 305 0.98

4 11 0.00051 0.11 15.0 2.3 1 23 311 333 311 333 0.95

5 11 1.1e-05 0.0023 20.3 0.8 1 23 339 361 339 361 0.97

6 11 3.5e-06 0.00078 21.8 0.1 1 23 367 389 367 389 0.98

7 11 0.00013 0.029 16.9 1.4 1 23 394 416 394 416 0.97

8 11 0.00014 0.032 16.8 0.2 1 23 422 445 422 445 0.95

9 11 0.00049 0.11 15.1 0.1 1 23 568 590 568 590 0.97

10 11 0.019 4.1 10.1 4.9 1 23 692 714 692 714 0.96

11 11 0.00013 0.029 16.9 4.3 1 23 724 746 724 746 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00034	0.076	15.6	3.4	1	23	227	249	227	249	0.98
2	11	0.0051	1.1	11.9	7.9	3	23	257	277	256	277	0.97
3	11	9e-05	0.02	17.4	6.5	1	23	283	305	283	305	0.98
4	11	0.00051	0.11	15.0	2.3	1	23	311	333	311	333	0.95
5	11	1.1e-05	0.0023	20.3	0.8	1	23	339	361	339	361	0.97
6	11	3.5e-06	0.00078	21.8	0.1	1	23	367	389	367	389	0.98
7	11	0.00013	0.029	16.9	1.4	1	23	394	416	394	416	0.97
8	11	0.00014	0.032	16.8	0.2	1	23	422	445	422	445	0.95
9	11	0.00049	0.11	15.1	0.1	1	23	568	590	568	590	0.97
10	11	0.019	4.1	10.1	4.9	1	23	692	714	692	714	0.96
11	11	0.00013	0.029	16.9	4.3	1	23	724	746	724	746	0.97

Sequence Information

Coding Sequence: ATGCCATACTTGCAGTTATCTGATGGTAATAATATAACAATACAGAAGGAAGGAAAAGGAAATATAACCCATGCAAATAAGGGGGTTGTGAGGAGGATGGTTTATGTGAGCGATTCATCATTTCAACAAGGAACAACTCAGAGGGTAATTACGACGGGCTCACCAGCCACAACAGCTGTGACAACACATAAAAAACATGATGTACTGAGTATGGGTTGTGATAAAAATTGTAATTGCAATGAGAATACAACGACAGCTATAACACCGATTTTTATTCAATCAGATCAATCAAATCATTCTATTGCCAATGGGATAATCGATTCAAAAACTCAAACAGTACTGACTTCAAGCGGTAAGGCGACACATTTTATGAGTCCAATTGGCCCCTTACAGTTAACCGCGGAAGAATACAGTGAAATACTAATGAAACGGGCGATGGCTCAACAAAATCAGCACACAATCACGACAACGACAAGCGACGGACATCACACCGAATTATGTTTCAAAGGTATTTCCGTTCAAGTTCAAAAGGTTATCCAGGGTTTAGAGGAGGCGGACGATTCACAAGCAACCTCGTCGACACATTGCAAACTTGAGCCCGTTCTTAGTATTTCACCGAAGCTAGAACATGAGGACCGGGATATGGAACCTAACCCGGCCACACCAAAAGAGAGGCCTTATTCATGCGACGAATGTGGAAAAAGTTTCCTACTCAAACACCATTTAACAACACATGCGCGAGTGCATACGGGTGAACGGCCACATGGTTGTGTTCACTGTGGCAAAACGTTTGCTCACAAACACTGCTTAAATACGCATTTGTTGTTGCATTCAACCGAACGTCCATATCAATGTAATGAGTGTAAGAAAAGTTTTACGCTGAAACATCATTTGCTCACGCATTCTCGGGTGCATAGTAGGGAACGTCCATTCGTGTGTCAAGAGTGTGGCCGGTCGTTTCCGCTTAAGAGACACCTAGTAACGCATAGTAAATTTCATGCTGGTGAACGGCCATTCGTGTGTGAAGATTGCGGCGAGAGTTTTGCTCAGAAAGAACATCTTGTGATGCATTCACGGTTTCACGGATCATTAAATCCATTTGTATGTCCCGATTGCGGTGCAACATTTCCACGTAAATTTCAACTGGTCAATCATGGAAGAATTCATGGACGGGTACCCCATTCGTGCACCGTTTGTGGTAAAGAATTTTTACAGAAACGAACATTGGTGGCGCATATGCGATTGCATACTGGCGATCAACCGTATCCTTGTACGGCGTGTGGTGAAGGATTCCGGACGAAAGCGGACTTAAATCAGCACAATCGTTTACAACACGGTGGAATTAATCCCAATTCTGCAAATACGACAATTGTGACGACACCAGATAATAAAATATTGATACAACAGACAGTACAGgctcatcagcaacagcagcaacaacagcagcagcagcaacaacagcagcagcagcaacaacaacagcagcagcagcagcaacaacaacaggccgcagctgctgctgctgctgcacaacaagcagcacaacagcaacagcagcaacaacaacaagctgctcaacaggctgctcaacaacagcaacaacagcagcagcaacaagcgcaaaccctcacagtggttaattcaaataacagtatggttattcaacaagccgcatcaccagaaacatcacctcggccgcaATACGCGTGCCGAGAATGTGGAAGTGCCTTTAATAGTCGTGAAGCATTAGCGTTACATTTACGTTTGCACACGGGCGATAAAAGTTTAATGACAGATTTATGTGCACTAACCGCCGCACTACCTGGTCACTTTTTGGCCAATACGAATCTAAATCAAGTagtgacggcagttccagtacaaataattacatcatctggtcaggttgtcaaccaaacgataccagtccaatcaccacctcaccaacaacaacaacagcagcagcaacagcagcagcaacaacagcaacaacaaacaaatgtggtatccacggttagtggcggtggtggtaatgccggtggtggtggaggacaTCATCAACCTAAACCAAAAACACATTTTTGTCCAAGCTGCTCGAAGGGTTTTGCATCTAAACATGGCCTGTTCCAACATAGTAAACGGCATCCGAATGGTGGATGTGCGGTACGACAACACGTGTGTGATAGTTGTGGCAAAGCTTTCTTCCAAAAGAACCATTTAATGTTGCATCAGCGTCAACATTTTGAAACCAAACCAAATTTAAGTCAGTTGCAACAGGTATCTCAAAATCAAACTCAAGAAGTGATTACGGTACAACAATCACAACAAATTACGCAACAGCAATTGAATCAATCGCAACAACAGCAGCAAAATCAACACCATCAACTAAATTCCCGTGAATTAGTAATAAGTAATCAACCTGTGCAAGTTCAAGTATTACAAGGTAATACCGCTCAAGTAATTAAATACGAGATCAATATTCCGCAGGATTCGCATCAAGCGATCGAGTGA
Protein Sequence: MPYLQLSDGNNITIQKEGKGNITHANKGVVRRMVYVSDSSFQQGTTQRVITTGSPATTAVTTHKKHDVLSMGCDKNCNCNENTTTAITPIFIQSDQSNHSIANGIIDSKTQTVLTSSGKATHFMSPIGPLQLTAEEYSEILMKRAMAQQNQHTITTTTSDGHHTELCFKGISVQVQKVIQGLEEADDSQATSSTHCKLEPVLSISPKLEHEDRDMEPNPATPKERPYSCDECGKSFLLKHHLTTHARVHTGERPHGCVHCGKTFAHKHCLNTHLLLHSTERPYQCNECKKSFTLKHHLLTHSRVHSRERPFVCQECGRSFPLKRHLVTHSKFHAGERPFVCEDCGESFAQKEHLVMHSRFHGSLNPFVCPDCGATFPRKFQLVNHGRIHGRVPHSCTVCGKEFLQKRTLVAHMRLHTGDQPYPCTACGEGFRTKADLNQHNRLQHGGINPNSANTTIVTTPDNKILIQQTVQAHQQQQQQQQQQQQQQQQQQQQQQQQQQQQAAAAAAAAQQAAQQQQQQQQQAAQQAAQQQQQQQQQQAQTLTVVNSNNSMVIQQAASPETSPRPQYACRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLANTNLNQVVTAVPVQIITSSGQVVNQTIPVQSPPHQQQQQQQQQQQQQQQQQTNVVSTVSGGGGNAGGGGGHHQPKPKTHFCPSCSKGFASKHGLFQHSKRHPNGGCAVRQHVCDSCGKAFFQKNHLMLHQRQHFETKPNLSQLQQVSQNQTQEVITVQQSQQITQQQLNQSQQQQQNQHHQLNSRELVISNQPVQVQVLQGNTAQVIKYEINIPQDSHQAIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01455098;
90% Identity: iTF_01456697;
80% Identity: -