Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371223.1:181161281-181171110[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 4e-05 0.0088 18.5 2.0 1 23 72 94 72 94 0.99

2 11 0.00034 0.075 15.6 3.5 3 23 102 123 100 123 0.95

3 11 0.0001 0.023 17.2 1.9 1 23 129 151 129 151 0.98

4 11 9.4e-06 0.0021 20.5 0.3 1 23 157 179 157 179 0.98

5 11 0.00031 0.069 15.7 0.2 1 23 185 207 185 207 0.98

6 11 3.8e-07 8.5e-05 24.9 0.5 1 20 213 232 213 233 0.97

7 11 0.0022 0.48 13.1 3.3 2 23 243 262 242 262 0.97

8 11 1.7e-05 0.0037 19.7 1.1 3 23 270 290 269 290 0.99

9 11 2.2e-05 0.0048 19.4 1.1 1 23 296 318 296 318 0.99

10 11 0.0048 1.1 12.0 0.2 1 23 324 351 324 351 0.94

11 11 0.026 5.8 9.7 0.1 1 20 357 376 357 378 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	4e-05	0.0088	18.5	2.0	1	23	72	94	72	94	0.99
2	11	0.00034	0.075	15.6	3.5	3	23	102	123	100	123	0.95
3	11	0.0001	0.023	17.2	1.9	1	23	129	151	129	151	0.98
4	11	9.4e-06	0.0021	20.5	0.3	1	23	157	179	157	179	0.98
5	11	0.00031	0.069	15.7	0.2	1	23	185	207	185	207	0.98
6	11	3.8e-07	8.5e-05	24.9	0.5	1	20	213	232	213	233	0.97
7	11	0.0022	0.48	13.1	3.3	2	23	243	262	242	262	0.97
8	11	1.7e-05	0.0037	19.7	1.1	3	23	270	290	269	290	0.99
9	11	2.2e-05	0.0048	19.4	1.1	1	23	296	318	296	318	0.99
10	11	0.0048	1.1	12.0	0.2	1	23	324	351	324	351	0.94
11	11	0.026	5.8	9.7	0.1	1	20	357	376	357	378	0.92

Sequence Information

Coding Sequence: ATGAAAATTGAAAAATGTGATCTCGAAAATGAAATCAAATGTGGTAGTAAAAATAATTGTGAGCCTGATAAAAAAACGAAAATTGATGAAAATGAGAATGAAACAAAAGATCTAGTCGATATAGTAGTTGCCACAGCCGTTACTGATGGCACCGGAGATACCAAATCGCTAAAAAAGCGACGTGCGAAGCGGAAACCACGTGTCAAAAAAATCTACCAATGTGATGTGTGTCACAAAATATTTCAGGGATTAAACGATTTACGAAAACATTATCGCATACACAGTGATGAACGGCCGTATGGATGCGATCATTGTAGTAAAAAGTTTCGGCAAGCAGGTTGTTTAAAAAATCATATAGCGTCGCAACATGGTACCGATACTAAATTTATATGCCATTTTTGTGACAAATCGTTCCCAATCAAGGAAAGACTTCGTTTACATTTGCGAATACATTCTGGCGAGAAACCCTATAAATGTGCATATTGCCAAAAAACATTTGCGCGCGGCGGCCAATTAACACAACATTTAGCGATACATAATGGATATAAAAAATATCGGTGTGACTTTTGTACAGCAGCATTCGCATTTGCAGCTAATTTGAAGTTACATACTAAAATTCATACGAACGAGCGGGATTACACGTGTCATGTTTGTGGCAAGACGTTTGTCCGTTCTGATGCGCTAAGAAAACATTTAGATTGCATTCACGCAAATCTAAAAACCAAACGCTGTGATATTTGTAACAAAGATTTTAAAGGCCATTTACTGCAGCACATGCGAACGCACAAAAATGTACGGCCTCATGGTTGCGCTGTATGCCATGCAAAATTTTCGCAACGTTCACAATTGATCGTGCATCAACGCACACATTCAGGTGAACGACCGTATCGATGTCAAGTTTGCTGGCAAGCTTTTGCTCATTCGAGTGTGCTAAAACTACACATACGTAAGCATACGGGTGAAAAACCGTTCAAGTGTGAACTATGTCCGGCCGAGAATGAAACCGCATTTTCTCAACTTCCTCATCTTAAAAAGCATATGTCAGCGATACACGGTCTAGATAAAACGTATTTGTGTGCAGAATGTGGCCAATATTTTAAAACAAAATTGGAATATGCTGTTCATCAAACGGAATGTCTAAAACGTAATCGAGCAAATAACCAGGATGATGTTGATGGAGTGATCAACGGCATGATGCAAAATAATGAATCAAGTGCTTCTTCTGGAGAGCCTCATGACGAAACCGACGAAAAGGTTCCCAAATCAAAACGAGAATATATCAAAAGTGATTTCGATTATCCGCCAACTCCAATGGCGGTCACCAGGATGAGATTACTTGTCGCAATATTACTCCGACGTATTTCATCGGAGGACCGCCTTAAGCAATTAGGCTACGAGAAACGACTGATCGATAACGTATTGGTTGATTCATTGAAACTAGCAGATCGCACCGTTTGCGAAGATAGGTCGCTAACGGAAGCAGAGCGACTTAAGATTAATATAAGGGAATGGCTAGAGTGGTTGGTACCATCGGATTATATGCAAAAATTTCAATCGGAGCAACGAAGTACAGAAGAGTTACTCGAGCAACTCACCCGAATTTAG
Protein Sequence: MKIEKCDLENEIKCGSKNNCEPDKKTKIDENENETKDLVDIVVATAVTDGTGDTKSLKKRRAKRKPRVKKIYQCDVCHKIFQGLNDLRKHYRIHSDERPYGCDHCSKKFRQAGCLKNHIASQHGTDTKFICHFCDKSFPIKERLRLHLRIHSGEKPYKCAYCQKTFARGGQLTQHLAIHNGYKKYRCDFCTAAFAFAANLKLHTKIHTNERDYTCHVCGKTFVRSDALRKHLDCIHANLKTKRCDICNKDFKGHLLQHMRTHKNVRPHGCAVCHAKFSQRSQLIVHQRTHSGERPYRCQVCWQAFAHSSVLKLHIRKHTGEKPFKCELCPAENETAFSQLPHLKKHMSAIHGLDKTYLCAECGQYFKTKLEYAVHQTECLKRNRANNQDDVDGVINGMMQNNESSASSGEPHDETDEKVPKSKREYIKSDFDYPPTPMAVTRMRLLVAILLRRISSEDRLKQLGYEKRLIDNVLVDSLKLADRTVCEDRSLTEAERLKINIREWLEWLVPSDYMQKFQSEQRSTEELLEQLTRI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01455090;
90% Identity: iTF_01053677; iTF_01054614;
80% Identity: -