Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371223.1:178223295-178234951[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00012 0.027 17.0 0.2 1 23 575 597 575 597 0.94

2 12 0.00046 0.1 15.2 1.7 1 23 606 628 606 628 0.98

3 12 0.00059 0.13 14.8 0.5 2 23 636 657 635 657 0.97

4 12 6.1e-06 0.0013 21.1 1.8 1 23 663 685 663 685 0.99

5 12 0.00035 0.078 15.6 1.7 1 23 692 714 692 714 0.98

6 12 2e-05 0.0045 19.4 1.7 1 23 720 742 720 742 0.96

7 12 7.6e-05 0.017 17.6 0.3 1 23 748 770 748 770 0.98

8 12 9.5e-06 0.0021 20.5 0.9 1 23 776 799 776 799 0.96

9 12 0.00025 0.056 16.0 2.1 1 23 805 828 805 828 0.94

10 12 0.00024 0.052 16.1 2.5 1 23 834 856 834 856 0.99

11 12 0.00018 0.039 16.5 1.5 1 23 862 884 862 884 0.97

12 12 0.0014 0.32 13.6 0.2 1 21 890 910 890 914 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00012	0.027	17.0	0.2	1	23	575	597	575	597	0.94
2	12	0.00046	0.1	15.2	1.7	1	23	606	628	606	628	0.98
3	12	0.00059	0.13	14.8	0.5	2	23	636	657	635	657	0.97
4	12	6.1e-06	0.0013	21.1	1.8	1	23	663	685	663	685	0.99
5	12	0.00035	0.078	15.6	1.7	1	23	692	714	692	714	0.98
6	12	2e-05	0.0045	19.4	1.7	1	23	720	742	720	742	0.96
7	12	7.6e-05	0.017	17.6	0.3	1	23	748	770	748	770	0.98
8	12	9.5e-06	0.0021	20.5	0.9	1	23	776	799	776	799	0.96
9	12	0.00025	0.056	16.0	2.1	1	23	805	828	805	828	0.94
10	12	0.00024	0.052	16.1	2.5	1	23	834	856	834	856	0.99
11	12	0.00018	0.039	16.5	1.5	1	23	862	884	862	884	0.97
12	12	0.0014	0.32	13.6	0.2	1	21	890	910	890	914	0.92

Sequence Information

Coding Sequence: ATGATTCTCTACGAATTAAAGCTTGCGCAATTAAAGGAGCAGCTGAAACAGCGAGACAAGTATGATTTCGAGGAGGAAAAACCGGATGAGATCAGTGTGGACCAGAAAGAAAAGGACGTGCAAACGGTGGTCGGAGCAGCACAAAACCCATCTGGAAGTTTTGATTTATCGCAGTTAATGGCAGCTATGAATCAAATGATGGGTCAACAGTTGGGTGGAATTAAACAATCTATGGAGCAACAAGGGGCGGACATTAAACATCAAATGAAACAGCAGATGGAGCAACAAGGGGCGGACATTAAACATCAAATGAAACAGCAGATGGAGCAACAAGGGGCGGACATTAAACAATCGAACCAGGAAATGAAACAGAAGATGGTACAAATGGAGCAACAAGGAGCGGACATTAAAAACCAAATAGAAGTTGGCCAAAAGAATATGGACGAGAAGTTTCTGGAGTTATCTTCTACACTACACGGTAAAGTGGAAAAACTGCAAACAGAAGTACACGCAGAAATTCAAAATGTTAAACAAAATCTACAAACGGAAGTTAAACGACTCGAGAAGGAGCTCCAAGATGTCAAGTCAAATGGaacaacaggtcaaATGAAAAATGAAAATGATGATGTTGGAAGTGAATATGCCAAACAACAACAGCACAATGTTGAAATAATGAAAATTGGAACTTGCTTCATCTGTAATTCAGAGTTTGGTAGCGACAGAAACGCTGAACTAAATTTATTTACAGATCGTACTCCAATCAATGATTTATCACCATCATTCATTCTCTCTCAAATATTGAACCGGCCTCTGGGTAGCGATACCGTTCATTCTGATTCGCTGTGTCAAAATTGTTTTAAATTATGTTTAGAATTTGAAGAACTGGAACAGCGGTTAGTTGAAATCCGTCTTGAATTCATTCGTAATTTTAACAATACAGCAATCACCTACAATTTGGAACCAGTTGAACTTGAAGACGATGAAGTCGAAGATGATAATCTAGCCGAGGAAAATTTGGTGGAAGAGGATGATGAATGTGATGAGAATGATGGCGATGAAGAGCAAAAACATGAAACTGTACACAATGAAACTCGCGAAGGTGAAATCCTAGAAGATCCATTGGAAAAGATTCCGCGTCACCATCAGGAAATTTTGGAACAATATGAAACGACTGAGGCTAATGAAGCGGGAAAAGAATCAAGAGTCATACTTTTGGATAATTTGCAAGCCACAAGCTTAGTGCAGGAAGGACACCATAGTAATACTGCAACATATTCGATTGATGCAACTCACTTTCGGGAAGAATACCTTAGCGAAGAAAATCATAATATGGTCGAGGTCGTTGCAGAATCGGAGGACTACGTCGATTTGATTGTACATGAAAATCAGATGTCGTTACACGATGAAAATTCGTATGAGAGTGGAATTGTTAAGGACAATTCAAAATCATCCGATAATAGCCAGGATAGTAATCGAAATCATCTGTTCCAAATCAAAGTTGAACAAAGTGATAATAGTGAAAGTGCGTTCAGTGTTCCATCAAATAAAACAAAACGGAAAATTACCAAAACAGAAAAGGATGCTATTGTGTTGAGCACAAACGAGATTTTCACCCGAGAAGGCGATTCCTACGTTTGCCGATTATGTCTTGATAAAAATATAATTATTTACGATGGGCGGACCATCGGAATTCATTTGAAATCGATCCACGATATTAAAATTTACTTATGTGACATATGTGGCCAAGACTTTCGCAAGCGAAGCGAGCTCACAGAACATTTGGATGAGCATGTATCGGCAACAGAGGACGGGTTCTTCACCTGTGATTTATGTAATAGAGAATTTAATAATTTACGTCTCTTCCGAATACACAAACGTATACATTACACGAACTCAAAGTCATGGCCTTGTACAAAATGTAATAAAAAGTATGGATCGAAAAATTTGCTGGACGAGCATATGAATATGCATACAGGGAAACGACCATATAAATGTGCTCATTGCGAAAAAGATTTTGCATCTAAATATACTCTATCAGCCCACATGAAAATTCATTCCGATCGTAAAAGGCCGTTTAATTGCCGGACATGTGACAAATCATTTTATAGTGGACAAAATTTAATACAACACGAAAAAACGCACACCGGTTTGCGACCGCATGTCTGTGAAGCATGCGATAAATCTTTTAGTACGCAACATAATTTGGAGGTTCATAAAATTGTGCATACCGGGTTTAAACCATTTATTTGTAGGACTTGTGGTAAAGCATTTGCACGACGAGCTGAAATTAAGGATCACGAGCGTACGCATACTGGTGAAAAGCCGTTCAAATGTGATTTATGTAATGCCAGTTTTGCACAACGATCAAATTTGCAGTCTCACAAAAGGGCTACGCATTTAGATGATAAACGATATCAATGTGACATTTGTGATCGCCGGTTTAAAAGACGACGATTATTAGATTATCATAAGAAAGCCACCCATACAGGTGAACGACCATTTCAATGTCGTCTCTGCTCGGCCACATTTGTTTACCCCGAACACTATAAAAAACACTTGCGCATACACACCGGCCTTAAACCGTATTCATGTGAAATATGTAAAAAAATGTTTAATAGTCGAGACAATCGGAATGCACATCGATTTGTGCACAGCGATAAGAAACCTTATGAATGCACAACATGTGGTGCTGGTTTTATGCGAAAACCATTACTATTTGCGCACATGCATCAGGCGGCCCATTTTTCGGATGCTATCATTATTAACCAACCGCGAATCCAATCGATGGTAACTGCAACTAATCCAAAAGATGGCAAAAATGAAGTTGTATTTAAAACGGAAAAGGTCGTTGTTGATAAAGATAATTCAAATGATGTGTTTACGGTGGAATATATTGACGGAGAGCAAATGGATGACGGTGAAATAATTGACGGCGACCAAAATTTATTAGATAACGAAATGGAATCAATACTTCCTGATGATGAAGGAAGACATGAGATGGAAGGCGATGACGAAGATATGCCTGAAGATCATATTGTCGGTGAAGAGTTATCAGTTGAACACATTCTAGACAACTCCAATTTTTCCACCGAAACTATTGAACCCGGAACGGAAATTTTTATAACAGAAGAAGGACAGCTATACGAAACTGCTAATGGAACAATACACTATGTGAAAATCATAAATGATGCAGAGACGTTGAACAATAATAAAAATGTATCAATAAAATTGGAGTAA
Protein Sequence: MILYELKLAQLKEQLKQRDKYDFEEEKPDEISVDQKEKDVQTVVGAAQNPSGSFDLSQLMAAMNQMMGQQLGGIKQSMEQQGADIKHQMKQQMEQQGADIKHQMKQQMEQQGADIKQSNQEMKQKMVQMEQQGADIKNQIEVGQKNMDEKFLELSSTLHGKVEKLQTEVHAEIQNVKQNLQTEVKRLEKELQDVKSNGTTGQMKNENDDVGSEYAKQQQHNVEIMKIGTCFICNSEFGSDRNAELNLFTDRTPINDLSPSFILSQILNRPLGSDTVHSDSLCQNCFKLCLEFEELEQRLVEIRLEFIRNFNNTAITYNLEPVELEDDEVEDDNLAEENLVEEDDECDENDGDEEQKHETVHNETREGEILEDPLEKIPRHHQEILEQYETTEANEAGKESRVILLDNLQATSLVQEGHHSNTATYSIDATHFREEYLSEENHNMVEVVAESEDYVDLIVHENQMSLHDENSYESGIVKDNSKSSDNSQDSNRNHLFQIKVEQSDNSESAFSVPSNKTKRKITKTEKDAIVLSTNEIFTREGDSYVCRLCLDKNIIIYDGRTIGIHLKSIHDIKIYLCDICGQDFRKRSELTEHLDEHVSATEDGFFTCDLCNREFNNLRLFRIHKRIHYTNSKSWPCTKCNKKYGSKNLLDEHMNMHTGKRPYKCAHCEKDFASKYTLSAHMKIHSDRKRPFNCRTCDKSFYSGQNLIQHEKTHTGLRPHVCEACDKSFSTQHNLEVHKIVHTGFKPFICRTCGKAFARRAEIKDHERTHTGEKPFKCDLCNASFAQRSNLQSHKRATHLDDKRYQCDICDRRFKRRRLLDYHKKATHTGERPFQCRLCSATFVYPEHYKKHLRIHTGLKPYSCEICKKMFNSRDNRNAHRFVHSDKKPYECTTCGAGFMRKPLLFAHMHQAAHFSDAIIINQPRIQSMVTATNPKDGKNEVVFKTEKVVVDKDNSNDVFTVEYIDGEQMDDGEIIDGDQNLLDNEMESILPDDEGRHEMEGDDEDMPEDHIVGEELSVEHILDNSNFSTETIEPGTEIFITEEGQLYETANGTIHYVKIINDAETLNNNKNVSIKLE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01053681;
90% Identity: -
80% Identity: -