Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371223.1:170460917-170463816[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.6e-06 0.00036 22.9 1.0 1 23 173 195 173 195 0.99

2 14 0.17 37 7.1 1.9 2 14 198 210 198 217 0.73

3 14 8.1e-05 0.018 17.6 0.5 1 23 222 244 222 244 0.99

4 14 0.0004 0.089 15.4 4.0 1 23 250 272 250 272 0.98

5 14 0.00011 0.023 17.2 1.3 2 23 279 300 278 300 0.97

6 14 0.00034 0.075 15.6 4.3 1 23 450 472 450 472 0.97

7 14 0.19 42 6.9 1.8 2 14 475 487 475 494 0.71

8 14 0.00014 0.032 16.8 0.3 1 23 499 521 499 521 0.98

9 14 9.9e-05 0.022 17.3 4.9 1 23 527 549 527 549 0.98

10 14 7.9e-05 0.018 17.6 1.1 2 23 556 577 555 577 0.97

11 14 9.6e-06 0.0021 20.5 0.3 3 23 585 605 583 605 0.97

12 14 2.2e-06 0.00049 22.5 1.7 1 23 611 633 611 633 0.99

13 14 0.00046 0.1 15.2 2.6 1 23 639 661 639 661 0.99

14 14 0.0096 2.1 11.0 4.3 1 23 667 690 667 690 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.6e-06	0.00036	22.9	1.0	1	23	173	195	173	195	0.99
2	14	0.17	37	7.1	1.9	2	14	198	210	198	217	0.73
3	14	8.1e-05	0.018	17.6	0.5	1	23	222	244	222	244	0.99
4	14	0.0004	0.089	15.4	4.0	1	23	250	272	250	272	0.98
5	14	0.00011	0.023	17.2	1.3	2	23	279	300	278	300	0.97
6	14	0.00034	0.075	15.6	4.3	1	23	450	472	450	472	0.97
7	14	0.19	42	6.9	1.8	2	14	475	487	475	494	0.71
8	14	0.00014	0.032	16.8	0.3	1	23	499	521	499	521	0.98
9	14	9.9e-05	0.022	17.3	4.9	1	23	527	549	527	549	0.98
10	14	7.9e-05	0.018	17.6	1.1	2	23	556	577	555	577	0.97
11	14	9.6e-06	0.0021	20.5	0.3	3	23	585	605	583	605	0.97
12	14	2.2e-06	0.00049	22.5	1.7	1	23	611	633	611	633	0.99
13	14	0.00046	0.1	15.2	2.6	1	23	639	661	639	661	0.99
14	14	0.0096	2.1	11.0	4.3	1	23	667	690	667	690	0.96

Sequence Information

Coding Sequence: ATGGCACCGTACTCATTAAAACAAAGAATATTTATTGTAAAACGATATTATCAAACAGGAAATTCTGTATCGAATGTACAAAATGAATTTCCACACATATTCAACGTTAATTTAATACCAACTGATAATAGTATTATACAACTTGTGCAATGTTTTGAGGAGCACGGTAGCATAGTGGAAAAAATTGAAGATGAAATATTGAATGAGATTATTGAGGAACCTACACTGTTATTAGAAACTAAACTAGAAGATGAGCCATCTGAAAATAATTCCAGACAGAATACAGATGTGAAAGTTGAGCCACATTTATTGTTTAACCAATTAAGTGTTAAAGATGAACATTCCATTAAAGTTAAAGAAGAGGATTTGTACAGTGGTATCAATAACGACGATGTAGATGGAGGTAGTACATCAGATGATTGTACTATTTCAGATGATACGGATGAGGAAGTTGACAAAATCTTATTGAAAGATGATAGACCGAATGATAAGTCACCAGAAAATAGAAAGCATATTTATAAATGTAACGAGTGCAGTAAAATATTTGAACGTGAAATACAATTAAAACGTCACATAAATTCGCATGCAAGAACCTGCGAGATCTGCGGTAAGAAATACCGAGACCGAGAAACACATCTGCGGAAGCATACGGGAGAAAAACCATTTCAATGCCAACAATGTGGAGCCCAGTTTATTGATTTGACTCGGCTTAATAATCACATTAAAACTCATTCAGATGAGCGACCATTTGAATGCGATATATGCCATAAAACCTTTAAATTGCGTGATCGTCTTCGTGGCCATAAAAAGACTCATATTGTTGATCGGCCTATAAAATGTGAAGTGTGTGGCAAAGGCTTCCTGCACAACGGAAGACtgaaaaatcacatgcgaatgcataccggtgaaaaaccatcgGTGCAAAAGGAATTTCCACATGAATTTTATGATTTGCCATCACCCACGGAAGCCAGTATACACGTTTTAATAGGATTATTTGAAGAGTATGGAAGTGTAATTGATGAACCGAAAAAAGAAGAAAGTCTAGCGGATTTACCAAATATTTCGGCCAAATATGAAATAGAAGCGAATGCAAAAGAAACAATTTTAGATGAAGATGCTGATATTAAGATGGAGGTCACGGAGGAATTGCTTCCGCCGTCAATGCAGGCGAATGATGACAAAGATGATGAATCAAATTACAAAGATACGGACGATAATGATAGTGCCGAGGAGGAAAAACCAATAACGGCCGATATTATGAATGATGATGATAGTGTCGATGAGGAAAAACCAACAACCACCGATATTATAGATGATGATGAAAGTGATAAAAATGTAAAAAAGTTTACTTGTGAAATATGCCATAAAGAATTCCATCGAAGGCGTGCTTTAGTCCGACATACTACGGTGCATCAAAACACTTGTGAAATTTGCGGTAAAAAGTATCGTGATCGTGAACGTCACCTGCAAAAGCATACAGGCGAAAAATCATTTCAGTGCAGTCAATGTGGGGGGCGTTTCGTTGATATGAGCCGCTTGAAAACGCACATGATAATTCATTCGGATGAGCGGCCATTTGAATGTGAAACATGCCATAAGACTTATAAATCTCGTGACCGGTTACGAGACCATATGAAATATCATTTAACCGACCGTCCCATCAAATGTACGGTATGCGGTAAAGGTTTTCTACATAATGCTCCTCTTCGAAAGCATATGCGTTCTCATACAGGAGAAAAACCTTCGATTTGTGCCATTTGCGGTAAGAGTTACTCTTCCAATAAAGCTTTAACTATTCACAGTCGAACACATACCGGTGAAAGACCGTACCAATGTACATTCTGTCCAAAAGCGTTTAGCACTACCGGAACACTAAAAATTCACAAGCGCACGCATACGGGTGAACGGCCGTATAAATGCCAGTACTGTGAAAAGGGATTTCCTGATTCTTCAGCATGTAAATCACACGAACGGACCCATACCGGGGATTATCCATACAAATGTATACTATGTGGCAAAGCCCACAATCATCCGAGTAATTTAAAATCACATATGCGACATGCACATCGCGAACAGCAAGGTATACTCAATTAA
Protein Sequence: MAPYSLKQRIFIVKRYYQTGNSVSNVQNEFPHIFNVNLIPTDNSIIQLVQCFEEHGSIVEKIEDEILNEIIEEPTLLLETKLEDEPSENNSRQNTDVKVEPHLLFNQLSVKDEHSIKVKEEDLYSGINNDDVDGGSTSDDCTISDDTDEEVDKILLKDDRPNDKSPENRKHIYKCNECSKIFEREIQLKRHINSHARTCEICGKKYRDRETHLRKHTGEKPFQCQQCGAQFIDLTRLNNHIKTHSDERPFECDICHKTFKLRDRLRGHKKTHIVDRPIKCEVCGKGFLHNGRLKNHMRMHTGEKPSVQKEFPHEFYDLPSPTEASIHVLIGLFEEYGSVIDEPKKEESLADLPNISAKYEIEANAKETILDEDADIKMEVTEELLPPSMQANDDKDDESNYKDTDDNDSAEEEKPITADIMNDDDSVDEEKPTTTDIIDDDESDKNVKKFTCEICHKEFHRRRALVRHTTVHQNTCEICGKKYRDRERHLQKHTGEKSFQCSQCGGRFVDMSRLKTHMIIHSDERPFECETCHKTYKSRDRLRDHMKYHLTDRPIKCTVCGKGFLHNAPLRKHMRSHTGEKPSICAICGKSYSSNKALTIHSRTHTGERPYQCTFCPKAFSTTGTLKIHKRTHTGERPYKCQYCEKGFPDSSACKSHERTHTGDYPYKCILCGKAHNHPSNLKSHMRHAHREQQGILN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -