Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371225.1:53469206-53471451[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00018 0.041 16.4 0.3 1 23 166 188 166 188 0.96

2 14 8.4e-05 0.019 17.5 0.9 2 23 193 214 192 214 0.95

3 14 1.5e-05 0.0033 19.8 1.0 1 23 219 242 219 242 0.96

4 14 4.6e-05 0.01 18.3 5.3 1 23 248 270 248 270 0.97

5 14 0.00037 0.082 15.5 4.4 1 21 371 391 371 392 0.97

6 14 0.088 20 8.0 1.3 2 20 408 426 407 429 0.94

7 14 3.7e-05 0.0081 18.6 2.2 1 23 435 458 435 458 0.97

8 14 0.014 3 10.6 1.0 3 23 470 490 468 490 0.93

9 14 0.0019 0.42 13.2 2.1 1 23 496 518 496 518 0.97

10 14 5.4e-05 0.012 18.1 0.2 2 23 524 545 523 545 0.97

11 14 2.6e-07 5.7e-05 25.4 0.6 1 23 550 572 550 572 0.99

12 14 0.024 5.3 9.8 4.8 1 23 578 601 578 601 0.98

13 14 3.1e-05 0.0068 18.9 0.9 2 23 608 630 607 630 0.96

14 14 4.6e-05 0.01 18.3 1.5 1 23 636 659 636 659 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00018	0.041	16.4	0.3	1	23	166	188	166	188	0.96
2	14	8.4e-05	0.019	17.5	0.9	2	23	193	214	192	214	0.95
3	14	1.5e-05	0.0033	19.8	1.0	1	23	219	242	219	242	0.96
4	14	4.6e-05	0.01	18.3	5.3	1	23	248	270	248	270	0.97
5	14	0.00037	0.082	15.5	4.4	1	21	371	391	371	392	0.97
6	14	0.088	20	8.0	1.3	2	20	408	426	407	429	0.94
7	14	3.7e-05	0.0081	18.6	2.2	1	23	435	458	435	458	0.97
8	14	0.014	3	10.6	1.0	3	23	470	490	468	490	0.93
9	14	0.0019	0.42	13.2	2.1	1	23	496	518	496	518	0.97
10	14	5.4e-05	0.012	18.1	0.2	2	23	524	545	523	545	0.97
11	14	2.6e-07	5.7e-05	25.4	0.6	1	23	550	572	550	572	0.99
12	14	0.024	5.3	9.8	4.8	1	23	578	601	578	601	0.98
13	14	3.1e-05	0.0068	18.9	0.9	2	23	608	630	607	630	0.96
14	14	4.6e-05	0.01	18.3	1.5	1	23	636	659	636	659	0.96

Sequence Information

Coding Sequence: ATGAATAAAGTAAATAGTGTTAAAATATGTCGGGCATGTTTATCGGAAACCTTTATTTATTTCAATATATACGAAACGCTTTATTATTTCAATACCCGTCAGATACCCGATAAAGAAGTTCCAGTCGCTGAAATTTATGAACGATTGACGGGGAATACTTTAAATGAAAATAATGAAAAACTCCCAAAAAATTTATGTTTAACGTGTCTAGAAAAGTTATTTAACGCCTGTGACTTTTTAGAATTATGTAAAAATTCTGAACGACAGTTGCAATCTTACCATAGTGCTGTAAGTGAAATCGAAATTCCCGAATGTGTTGACAACAGTCTAGAAGATGATGATAATAGCATATCGGACGATCTTGAAGCCGGATCGAGTGATTCAAATGATGAAGATGATTCATGCAGTGAAGATGGTTATCCTGATTGCGATTCTAACGCTAATAATGCATCTGTCGAAAGCAATGTACCAAAGCCTAACAATTCTCGAACACGTTACGAATGCATTAAGTGTAATGAGGTTTTTAATAGAGCAGCCCAATTAAGGAAACACGAAAAAATTCATACGGGGAACTGGAAGTGTTCAGAATGTGATAAAATACTTGCAAATAAGTATTCTTTGCGTCATCACATGGTACTGCACACTGGTAAACCTCACGAATGTGGAGTGTGCAAAAAAAGATTTGCAGTTCCATCGGAATTGACCCGCCACACGAAAATATACCATAAAAATGGTAAATCTTATGCATGTGATCATTGTCCTAAACGATACTATACGAAGAGCCATTTGACTAGTCACAAAATAACTCATCTAAACAAAAAAGATAATTTGCATATTTCAGAAATTGACAATCATATAATGGTTAAAAATGACGACACGCAATGTGAGGCAAATGAGTCAAAATATGAGGCCTCCGAAGCATCGAATACCAATAACTTTTCGACCGATGGTGAAACAACAAATTTTAAAGAATCCTCCCAATGTGCAAATGATTCTACTTCACCGCATCGAAATTTTCCATTCAATACAAACATGAATGAAGAAAATGAAGGCCATTTGAATAATGTTAGTAAAGAAAGCCCACTCAACGTTGCTGAAGATATCGAATTTTATAGATGTAAAACATGTTTTAAAAAATTTCGGCATAAGGCCAATTATTTGAGCCACATGAAACTTCAATTAAATTGTAAAGACGATTTAAATACAAATAACAATCCCCAGAAGTGTGATTACTGTGATATCATATCAGACAATGTGTATCAACTACGAAAGCATTTAGAATGTCATTTGGATAAAGAACCGTTTAAATGTAAGCTATGCGAAAAAAGTTATAAAACTTGGATAAAATTAACGGTGCACACACGGCAAACTCACCTGACAAAAACCAAATATCGTAAAAGTCATTTATGTACTCTGTGTGGCCGTGGATTTTTCACCTCAAAACTCTTGGATGAACATTATCTAGCCCATCAAGGTATTCGAAAATATAAATGCGATACATGTGATAGTTCGTTCTGTACTGTGTACGGATTGAAACAGCACGCAACCATTCATACAAGAGATGTGCTGCAATGTAGTGAATGTGGCAAAATTTTGGCAAATAAAATGTCCCTTAAAAGTCATATGACCATACATTTTGGTAAGAAGTATCAATGTACGATTTGTGAAAAATATTTTCCTAATCCGGCTACGTTAAATCGACACATGAAAAGCCATCGAGGCGAACGGAATTATGTATGCGATCGATGTTCAAAGCGATATACGTGCCGAGGACATTTAAACGAGCATATTAAAAAGATACATGAAAATCCAACAACGTTAAAATGTGATGAATGTGGTAATGAATTTGCCCATCGAAGAGCCCTAAAGAAACACATAAGGCTTGAGCATGCCGAAAAAAAAATATTTAATTGTGATGTGTGTGGGAAAACTTATGGTAGAAAATCAAGATTGAAAGAACATAAAAAGAAAGCGCATGCAATATCCGTGGTTGCGGATCCCATACCTATAATACAAAACCAAATAGAACAGAATATAGCAATTTCAATAGCCACCTATAATCAGCCAGATACTGGAATTATTATGGTTGAAATGTTTAAAAGTGATGAATGTTAA
Protein Sequence: MNKVNSVKICRACLSETFIYFNIYETLYYFNTRQIPDKEVPVAEIYERLTGNTLNENNEKLPKNLCLTCLEKLFNACDFLELCKNSERQLQSYHSAVSEIEIPECVDNSLEDDDNSISDDLEAGSSDSNDEDDSCSEDGYPDCDSNANNASVESNVPKPNNSRTRYECIKCNEVFNRAAQLRKHEKIHTGNWKCSECDKILANKYSLRHHMVLHTGKPHECGVCKKRFAVPSELTRHTKIYHKNGKSYACDHCPKRYYTKSHLTSHKITHLNKKDNLHISEIDNHIMVKNDDTQCEANESKYEASEASNTNNFSTDGETTNFKESSQCANDSTSPHRNFPFNTNMNEENEGHLNNVSKESPLNVAEDIEFYRCKTCFKKFRHKANYLSHMKLQLNCKDDLNTNNNPQKCDYCDIISDNVYQLRKHLECHLDKEPFKCKLCEKSYKTWIKLTVHTRQTHLTKTKYRKSHLCTLCGRGFFTSKLLDEHYLAHQGIRKYKCDTCDSSFCTVYGLKQHATIHTRDVLQCSECGKILANKMSLKSHMTIHFGKKYQCTICEKYFPNPATLNRHMKSHRGERNYVCDRCSKRYTCRGHLNEHIKKIHENPTTLKCDECGNEFAHRRALKKHIRLEHAEKKIFNCDVCGKTYGRKSRLKEHKKKAHAISVVADPIPIIQNQIEQNIAISIATYNQPDTGIIMVEMFKSDEC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01053673;
90% Identity: iTF_01053673;
80% Identity: -