Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371223.1:300839660-300851195[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 3.5 7.8e+02 3.0 1.9 1 23 172 196 172 196 0.87

2 19 8.2e-05 0.018 17.5 0.2 1 23 202 224 202 224 0.96

3 19 3.8e-05 0.0085 18.6 5.6 1 23 230 252 230 252 0.98

4 19 0.004 0.89 12.2 9.3 1 23 258 280 258 280 0.98

5 19 5.2e-05 0.012 18.2 1.4 2 23 286 308 285 308 0.95

6 19 0.0061 1.3 11.7 0.2 3 23 334 354 333 354 0.93

7 19 0.00026 0.059 15.9 8.5 1 23 360 382 360 382 0.97

8 19 0.0002 0.044 16.3 3.2 1 23 401 423 401 423 0.94

9 19 1.5e-05 0.0033 19.9 1.5 1 23 429 452 429 452 0.96

10 19 0.00069 0.15 14.6 0.4 2 23 461 482 460 482 0.96

11 19 0.00017 0.037 16.6 0.2 1 23 820 842 820 842 0.95

12 19 3e-06 0.00067 22.1 4.2 1 23 848 870 848 870 0.97

13 19 0.0011 0.24 14.0 4.9 1 23 876 898 876 898 0.98

14 19 0.00014 0.03 16.8 2.8 2 23 908 930 907 930 0.94

15 19 1.1 2.5e+02 4.5 0.1 2 11 950 959 949 971 0.86

16 19 3.8e-05 0.0084 18.6 3.8 1 23 977 999 977 999 0.96

17 19 0.0001 0.023 17.2 2.9 1 23 1018 1040 1018 1040 0.94

18 19 0.0014 0.32 13.6 2.5 1 23 1046 1071 1046 1071 0.94

19 19 1.4 3.1e+02 4.2 0.4 3 16 1106 1119 1104 1119 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	3.5	7.8e+02	3.0	1.9	1	23	172	196	172	196	0.87
2	19	8.2e-05	0.018	17.5	0.2	1	23	202	224	202	224	0.96
3	19	3.8e-05	0.0085	18.6	5.6	1	23	230	252	230	252	0.98
4	19	0.004	0.89	12.2	9.3	1	23	258	280	258	280	0.98
5	19	5.2e-05	0.012	18.2	1.4	2	23	286	308	285	308	0.95
6	19	0.0061	1.3	11.7	0.2	3	23	334	354	333	354	0.93
7	19	0.00026	0.059	15.9	8.5	1	23	360	382	360	382	0.97
8	19	0.0002	0.044	16.3	3.2	1	23	401	423	401	423	0.94
9	19	1.5e-05	0.0033	19.9	1.5	1	23	429	452	429	452	0.96
10	19	0.00069	0.15	14.6	0.4	2	23	461	482	460	482	0.96
11	19	0.00017	0.037	16.6	0.2	1	23	820	842	820	842	0.95
12	19	3e-06	0.00067	22.1	4.2	1	23	848	870	848	870	0.97
13	19	0.0011	0.24	14.0	4.9	1	23	876	898	876	898	0.98
14	19	0.00014	0.03	16.8	2.8	2	23	908	930	907	930	0.94
15	19	1.1	2.5e+02	4.5	0.1	2	11	950	959	949	971	0.86
16	19	3.8e-05	0.0084	18.6	3.8	1	23	977	999	977	999	0.96
17	19	0.0001	0.023	17.2	2.9	1	23	1018	1040	1018	1040	0.94
18	19	0.0014	0.32	13.6	2.5	1	23	1046	1071	1046	1071	0.94
19	19	1.4	3.1e+02	4.2	0.4	3	16	1106	1119	1104	1119	0.89

Sequence Information

Coding Sequence: ATGGAAATTGAAATCAAGTTAAATTCATGCCGTGTTTGCTTGAAAAATGTTGGGGTAATTCCATTTTTTAACGATGAGAGCGACGAGATTGCTGCCGAGCTGATAAGTACCCTGTTTAATATTTTTGTAGTCTGTGATCCAAATTTACCAGACACATTATGCGCAAGTTGTATGGATAATCTAAAAATTGCTGCCGCTATCAAAGATGCCATTATTAACTCAGAGGATGTTCTGAACTCCCTCTTGAAGCTGGTCATTGGACCAGCTAAAACCGAATGTAAAGAAGAATACGATATCGAGCAGAGAAACAATACAAACTTTCAAGACACATCACGGTTGGTTGCTTTAAATGTGGAGCATGTTAACAGTGAAACAGACGACAGTTTAGAGGGTCGTTTAATTTTATCGACTCCATCGGAGCATGAATTTGAATTGGATGAGGAATACTTGAGTTGCGAAATTCCTTTACCACCGCCGGTTATTGTGGATTCTTCATTGTCCCACTTTAATATTTATGATTGCTGGAGTGAGAGCTGCGATTTTAAAACTGATACGTATAAACGGGTAATTCATCATATGAGAACTCACGCAGAAATAAAAATGTATGAATGTGAAGATTGTGGTAAAGAATTTAAGAAAAGGTCAAAATATGGTGTACATATCGCAGGACACCGACCCGAAAGGCCTTATGAATGCCACTACTGTACCAAAAAATTTAAGGGCCAATTTAATCTTCGCCAACATATTTTTACTCACAACACCGAGCGTATATTTAAATGCCAGCATTGTGAAAAATCATTTTGCCACATGAAAGCATTAAAACAGCATTTATATATGCACGGTGAAAAAAACGTTGTCTGCGAAATTTGCCACAAAACGTTTAAGCATTCAATAAACTTGGGCAATCATCAATTGGTGATCCATGGTCTTAGTGTTGAACAAAAGCCAAGCATAGTAATCAAAAAGACGTTTCCAGCGTCGAAACATGATAAGGCTCCATGTGAATTTTGTGGTAAAGTATTCTCAATCCAAAATTTAAAAACTCATGTCAAAGCGGTTCATTACAAGGAAAAACCACACAAATGTGCATATTGCGATAAATCATTTTCATCATCATGCAATTTAAGTACCCACATGCACTATCACATTAATTCGAAGCACGTTTCATTAGATGCTAAAACAACCGATTTATATCTAAAATATAAATGTGATGAGTGCGATAAGGGATTTTCAAGTAAAACTTGTTTGAAATTGCATAAGGTTTTGCATTCAGGTGTGAAAGAGCACGTATGTCCACACTGCGGTAAAGAATTCGCATTAAAGGTGTATTTAACGCGTCACGTTAGATTATTGCATAATAGAGCCGATCCAAGAAATTGTGTTTGTAACGTTTGTGGTAAAATTTCAGCCGATATGTCCGGATTAAAATCGCATATGCTGCAACATACAGGAGAAGCCCCATTCCATTGTGCAATTTGTAGTTCTAATTTCAGAGCGGCCCAGCAACAACGAAGAAGCTCCTTCCAACATCCAGGAGCAGTGGCATACAGTCAGCCATTACCACCGCGGCGCAAAACACTATCGGAAGAAGACGCGGCGCAAAACACTGTCGAAAATAAACGAAAGCTTCGTGAAAAATGGTTGGGTCGCAACACTAGAAGCACACAAGTAGAATATCTCCGCGCCAGGAAAGCCACGATTAAATACCTTCGACAAAAGAAACGCGATCATATGAGGTCATGCATTGAAAACATCAGCTTCCAAGCGGAAGTAGGAAATTCAATGGACTCTATTGCTAATGCCAGGAATCTCACTAAAGACTTCCACCCAAGAAGTACAGCCATCAAAGACGGAAATGGAGAATTGAGAACAAACGTGGTTGATGTTCTCTCAGTATGGCAACCCTACTTTCAAAATCTGCTAAATCGGAATGATGACGTGACCCCCATTAGAGCAATAGCTCCTCCAGGTGAAGAGGTAGTTTGTTACCCAAATTTACCCGACACAATATGTGCAAGTTGTATGGATAATCTAAAAAAAGCTGCCGCTATCAAAGAAGCCATTATTAACTCAGAGGATGTCCTGAACTCCCTCTTGAAGCTGGTCATTGGACCAGCTAAAATTGAATTTAAAGAAGAGTGCGAAATCGAGCAGAGCACCAATACAAACTTTCAAGACACATCACAATTGGGTACTTTAAATGTGGGGCATGTTAACAGTGAAACGTTAGACAACAGTTTAGCGAATCGTTTAATTTTATCAACCCCATCGGAGCATAAATTTGAATTGGATGAGAAATACTTGAGTAGCGAAATTCCTTTACCACCGCCGGTTAGTGTGGATTTTTCATTGTCCCACTTTAATATTTATCATTGTTGGAGTGAGAGCTGCGATTTTAGAACTGTTATGTATAAACGGCTAATTTATCATTTGAGAACTCACGCAGAAATAAAAATGTATGAATGTGAAGATTGTGGTGAAGAATTTAAGCTAAGGTCAATGTATCGTAAACATGTCGCAGGACACCGACCCGAAAGGCTTTATGAATGCCACCAATGTAACAAAAAGTTTAAGCGCCAAGTAAATCTTCGCCAACATATTTTTATTCACAACACTGAGCCTATATTTAAATGCCAGCATTGTGAAAAATCATTTCACAACATGAAAGCATTAAACCTACATTTATTAATGCACGGTAAACCTACATTTATTAAAAACGTTGTCTGCGAAATATGTCATAAAACGTTTAAGCATTCAAGATATTTAGCAAATCATCGATTAAATATCCATGGTCTTAGTGCTTCCAGCGTCAAAAAGACGTTTCCAGCGTCGAAACATAAAAGGGTACCATGTGAATTTTGTGATAAAGTATTCTCAATCAAAAATATAAGACCTCATGTCAAAGCGGTTCATTACAAGGAAAAACCACACAAATGTGTATTATGCGATAAATCATTTTCAACGGCAGGCAATTTAAGCACCCACATGCACTTTCACAGTAATTCGAAATACGTTTCATTAGATCCTAAAATATCCGATTTATATCTAAAATATAAATGTGATGAGTGCGATAAGCGATTTTCAAATACAACTTTTTTGAAAAAGCACAAGGTTTTGCACTCAGGTGTGAAAGAGCACGTATGTCCACATCCACACTGCGGTAAAGAATTCGCATTGAAAATGTATTTAACGCGTCACGTTAAATTAGTGCATACTACAGCCGAAGTGCATACTAGAGCCGATCCAAGAAATTGTAACAATTGTGGTAAAATTGTAGCCGATATGCTGCAAGATACAGAAGGAACCCTCGTCCATTGTAAAATTTGTCGTTATAAATTCAGGTATGCAAAATCACTGTGA
Protein Sequence: MEIEIKLNSCRVCLKNVGVIPFFNDESDEIAAELISTLFNIFVVCDPNLPDTLCASCMDNLKIAAAIKDAIINSEDVLNSLLKLVIGPAKTECKEEYDIEQRNNTNFQDTSRLVALNVEHVNSETDDSLEGRLILSTPSEHEFELDEEYLSCEIPLPPPVIVDSSLSHFNIYDCWSESCDFKTDTYKRVIHHMRTHAEIKMYECEDCGKEFKKRSKYGVHIAGHRPERPYECHYCTKKFKGQFNLRQHIFTHNTERIFKCQHCEKSFCHMKALKQHLYMHGEKNVVCEICHKTFKHSINLGNHQLVIHGLSVEQKPSIVIKKTFPASKHDKAPCEFCGKVFSIQNLKTHVKAVHYKEKPHKCAYCDKSFSSSCNLSTHMHYHINSKHVSLDAKTTDLYLKYKCDECDKGFSSKTCLKLHKVLHSGVKEHVCPHCGKEFALKVYLTRHVRLLHNRADPRNCVCNVCGKISADMSGLKSHMLQHTGEAPFHCAICSSNFRAAQQQRRSSFQHPGAVAYSQPLPPRRKTLSEEDAAQNTVENKRKLREKWLGRNTRSTQVEYLRARKATIKYLRQKKRDHMRSCIENISFQAEVGNSMDSIANARNLTKDFHPRSTAIKDGNGELRTNVVDVLSVWQPYFQNLLNRNDDVTPIRAIAPPGEEVVCYPNLPDTICASCMDNLKKAAAIKEAIINSEDVLNSLLKLVIGPAKIEFKEECEIEQSTNTNFQDTSQLGTLNVGHVNSETLDNSLANRLILSTPSEHKFELDEKYLSSEIPLPPPVSVDFSLSHFNIYHCWSESCDFRTVMYKRLIYHLRTHAEIKMYECEDCGEEFKLRSMYRKHVAGHRPERLYECHQCNKKFKRQVNLRQHIFIHNTEPIFKCQHCEKSFHNMKALNLHLLMHGKPTFIKNVVCEICHKTFKHSRYLANHRLNIHGLSASSVKKTFPASKHKRVPCEFCDKVFSIKNIRPHVKAVHYKEKPHKCVLCDKSFSTAGNLSTHMHFHSNSKYVSLDPKISDLYLKYKCDECDKRFSNTTFLKKHKVLHSGVKEHVCPHPHCGKEFALKMYLTRHVKLVHTTAEVHTRADPRNCNNCGKIVADMLQDTEGTLVHCKICRYKFRYAKSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -