Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371223.1:376274737-376276694[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00085 0.19 14.3 2.4 1 23 255 277 255 277 0.96

2 12 5.2e-05 0.011 18.2 0.7 1 23 284 306 284 306 0.96

3 12 2.5e-06 0.00056 22.3 1.7 1 23 325 347 325 347 0.99

4 12 0.00064 0.14 14.7 4.4 1 23 356 378 356 378 0.95

5 12 0.0006 0.13 14.8 0.8 1 23 384 406 384 406 0.98

6 12 6.7e-05 0.015 17.8 4.2 1 23 412 434 412 434 0.98

7 12 3.3e-07 7.2e-05 25.1 0.8 1 23 440 462 440 462 0.96

8 12 0.02 4.4 10.0 0.9 1 23 468 490 468 490 0.97

9 12 4.7e-06 0.001 21.4 0.4 1 23 496 518 496 518 0.98

10 12 4.9e-07 0.00011 24.5 2.1 1 23 524 546 524 546 0.98

11 12 1.4e-06 0.00031 23.1 1.3 1 23 552 574 552 574 0.99

12 12 6.1e-06 0.0013 21.1 0.1 1 23 580 602 580 602 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00085	0.19	14.3	2.4	1	23	255	277	255	277	0.96
2	12	5.2e-05	0.011	18.2	0.7	1	23	284	306	284	306	0.96
3	12	2.5e-06	0.00056	22.3	1.7	1	23	325	347	325	347	0.99
4	12	0.00064	0.14	14.7	4.4	1	23	356	378	356	378	0.95
5	12	0.0006	0.13	14.8	0.8	1	23	384	406	384	406	0.98
6	12	6.7e-05	0.015	17.8	4.2	1	23	412	434	412	434	0.98
7	12	3.3e-07	7.2e-05	25.1	0.8	1	23	440	462	440	462	0.96
8	12	0.02	4.4	10.0	0.9	1	23	468	490	468	490	0.97
9	12	4.7e-06	0.001	21.4	0.4	1	23	496	518	496	518	0.98
10	12	4.9e-07	0.00011	24.5	2.1	1	23	524	546	524	546	0.98
11	12	1.4e-06	0.00031	23.1	1.3	1	23	552	574	552	574	0.99
12	12	6.1e-06	0.0013	21.1	0.1	1	23	580	602	580	602	0.99

Sequence Information

Coding Sequence: ATGGCTGAAATACCACCTCCACCCCCCAGTTGTGAAATCCCAACATTAAATCCGTATCTCGATTCATGTCGGATCTGTTTGACCAAGAATACTGCGCCCCAATCTTCTGTTTTTGCTAAATTAACAGAAGATATCAAATATTGTGATTTAATAACATTATTGGCACCGGTGAACATATATCCTAATGATGGACTAACGGAAAAGCTATGCAAAGAATGTACCGATAACTTGATTGGGGTTTATGACTTGCGTGCTCTATGTTTGAAAACGGATCGGGCCTTGCGGGAGACGGTTTTGGATGAGGCAGAAAATATTGACGTTAAGCCGGATATTATAGATGAAAGTGGCTTGATCATTAAAAAAGAAAGTCTGGAAGAGGGTGAACTAGAACCGGGAGAAATACGACATGGGGTGAAAGAATACCCAGAGACGAGTGAAAAAAACCGAGAAGAAATTACATTAGTCGACAGCAAAACAGAAAGGATACTTGATGAAACGTTTGCACATCATCATTCACTGGATGGTTCGTTAAGTATGAATGATGATAATGATTCAATTGGTGATGATTTCTATGGGGAAGATGATGAGGACGACGAGTTTGGTGAAGATGAGGATGATGATTACGAGCCTGAACACTTGATAAAAAACGAGCCATGCGATGTTAATATACAACTACTAAATAGCACGGGAACGGGTGGAACTATTCCTGATCAATTGGGCGATCGAAATTCCACCAGCGGAACGGGTAAGCGCAAAAAACAACACATATGTAAATTATGCAATAAGGCGTTCGACAAGGCATATCGGTTGAGACGTCACTCAAATATTCACGATGCCCGAGGAAAACAGTTCGAGTGTACCATATGCCATATATTCTTTGCGACCGAAAGTAGCCTTATTCGTCACGAGACTATCCATTCCGTACATCTAGCCGCAGCTTCCACATTACTAAATTCTGAAATTAAGAAGGAATTCAAGTGTATGGAATGTGATAAAGTATTTCAGAAACAAGAGTCCCTGTCATCACATATGAAGACTCATAAGAACGATGTCCTAAACAAGGAGTATAAATGTGAGTTTTGTCCGAAAGTTTTTAGCAAGCTGAACCTTCTAACGCGACATTGTAAATCTCACGATGAGATGAAGGTGCATCAGTGCAATATCTGTTACAAAACTTTTGCTCTCGGTGGCCAGCTCCTAGATCACATTAACAAGCATCGTGGAATTaaaccatacgtctgccatgtttgtaataagggtttccaacagtcgtgcactctaaaggatcatttaaggattcatagtggggagcagccatatttatgttcgcagtgcggaaaagcattcaataatagcagtaatttaagacagcatttaatccgacatacgggtattaaaccatacgcgtgtaatcagtgtccaagtcgattcagttgtcgagccggactgagatcgcatatacaaattcatacaggaattaaaccatatatatgcgatgagtgtggctcttcattcacaaaaccttattctctggctaaacataaacgaatacacaccggtgagaaaccgtatgcgtgcgatacatgcccaatgagatttaattcctctgaccatttaaaacgacacatacgaacacatacgggcgaaaaaccatataaatgtaaatattgtgaacgggcatttgcccaaagtaacgatctggtgaaacatacacggtctcatgttggggacaatacctatcaatgtagtaaatgtgatgcagcatttcggttgcagggcgaacttcgggatcatatacggatacatTTTCTAGCAGAGCAGGAGACTAAAATTAATCAGGGTCTACTGGACGAAGAGGGAGACCTGACAATACCAAAAAAAATTGGTAACCTACAAATTTAG
Protein Sequence: MAEIPPPPPSCEIPTLNPYLDSCRICLTKNTAPQSSVFAKLTEDIKYCDLITLLAPVNIYPNDGLTEKLCKECTDNLIGVYDLRALCLKTDRALRETVLDEAENIDVKPDIIDESGLIIKKESLEEGELEPGEIRHGVKEYPETSEKNREEITLVDSKTERILDETFAHHHSLDGSLSMNDDNDSIGDDFYGEDDEDDEFGEDEDDDYEPEHLIKNEPCDVNIQLLNSTGTGGTIPDQLGDRNSTSGTGKRKKQHICKLCNKAFDKAYRLRRHSNIHDARGKQFECTICHIFFATESSLIRHETIHSVHLAAASTLLNSEIKKEFKCMECDKVFQKQESLSSHMKTHKNDVLNKEYKCEFCPKVFSKLNLLTRHCKSHDEMKVHQCNICYKTFALGGQLLDHINKHRGIKPYVCHVCNKGFQQSCTLKDHLRIHSGEQPYLCSQCGKAFNNSSNLRQHLIRHTGIKPYACNQCPSRFSCRAGLRSHIQIHTGIKPYICDECGSSFTKPYSLAKHKRIHTGEKPYACDTCPMRFNSSDHLKRHIRTHTGEKPYKCKYCERAFAQSNDLVKHTRSHVGDNTYQCSKCDAAFRLQGELRDHIRIHFLAEQETKINQGLLDEEGDLTIPKKIGNLQI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01455074;
90% Identity: iTF_01054592;
80% Identity: -