Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371223.1:245650735-245652652[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0023 0.51 13.0 0.1 2 23 252 274 251 275 0.93

2 12 3.8e-05 0.0085 18.6 3.4 1 23 281 303 281 303 0.98

3 12 3.8e-05 0.0084 18.6 1.0 1 23 309 331 309 331 0.97

4 12 0.00014 0.031 16.8 2.4 3 23 345 365 343 365 0.95

5 12 0.00014 0.03 16.8 1.0 2 23 372 393 371 393 0.97

6 12 2.3e-06 0.0005 22.4 4.4 1 23 399 421 399 421 0.98

7 12 5.8e-06 0.0013 21.2 0.2 1 23 427 449 427 449 0.96

8 12 1.1e-06 0.00025 23.4 0.2 1 23 455 477 455 477 0.99

9 12 4e-06 0.00088 21.7 2.6 1 23 483 505 483 505 0.99

10 12 1.3e-06 0.00029 23.2 2.0 1 23 511 533 511 533 0.98

11 12 1.2e-06 0.00025 23.4 1.1 1 23 539 561 539 561 0.96

12 12 1.1e-06 0.00024 23.4 0.4 1 23 567 589 567 589 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0023	0.51	13.0	0.1	2	23	252	274	251	275	0.93
2	12	3.8e-05	0.0085	18.6	3.4	1	23	281	303	281	303	0.98
3	12	3.8e-05	0.0084	18.6	1.0	1	23	309	331	309	331	0.97
4	12	0.00014	0.031	16.8	2.4	3	23	345	365	343	365	0.95
5	12	0.00014	0.03	16.8	1.0	2	23	372	393	371	393	0.97
6	12	2.3e-06	0.0005	22.4	4.4	1	23	399	421	399	421	0.98
7	12	5.8e-06	0.0013	21.2	0.2	1	23	427	449	427	449	0.96
8	12	1.1e-06	0.00025	23.4	0.2	1	23	455	477	455	477	0.99
9	12	4e-06	0.00088	21.7	2.6	1	23	483	505	483	505	0.99
10	12	1.3e-06	0.00029	23.2	2.0	1	23	511	533	511	533	0.98
11	12	1.2e-06	0.00025	23.4	1.1	1	23	539	561	539	561	0.96
12	12	1.1e-06	0.00024	23.4	0.4	1	23	567	589	567	589	0.98

Sequence Information

Coding Sequence: ATGGTCAATTTAAGTGAACCCATAGAATTCGATAAAATTTGTCGTGGGTGTATGAATAAACAAATCGACATGAAACCTCTATACGGTTCGTCTTTAGACGAAATGTTTCGAACCGTTGTGAATGTTAACGTTTCGATGGGTGACGGCCTACCAGAACAAATGTGTGTCCAATGTATCTTACAAATTAGTCGAGCGTTTAGATTTCGGCAGCAATGCGAAAAGATCGATATTAGGCTCAGATCGTATTTAGAAGAAATAAATAAGCTTAATTTAGATGTTAGCGGAGATTTCAAAAACAAAGGGAATATTGCGAATGATGAACAAAGTGATGGCCGTGAGGTAAAAGACGTAAATAGTTTCGAGAATAGCAGTCTGACGCAAATTAATTTTTCCGAGGCAGAGGATCTTCCAAATAACACCGGGAATTTAATATTTGTGCAAAAAATAGAATCTGTTGAGTTACATGATGAAGCTCAGTACAATACCAATGTACACAGCGAACACCAAACTATTGTATTCGAAACAAACCATGGCGACAATACTGTAGAAGATACCAATATAGACCTGTGTGATGCCCAGATACATATTTTAAAGAATGTAAAGGTCGAAGGCTTGCACCATCACACTGACAACATGCTTATTGAAAATTATGAAACGTTCGCCAATAATATGCCCCTAATTGTGACCATCAACGAAGAAAACTTGAACCAATCCGAGTCACATGAAATTCAGTTAGGAGAAATAAAATCACTAGTCTGCCAATTATGTCTGATTGACTTCCGCGATGCTGACGAGCTTAAAGCGCATATGGAAGAAGTACATCATGTTTTGCAAACAACATTCGAATGCCATATCTGTAATAAGAAATTTGGTGAAAGCAAAGTTTTAAAACGCCATCTAAAAACACATTCACCAGATAAGCCTCATGTTTGTCTTACATGTGGCATGGCATTTGCCGAGGCCTCAAATCTTACCAAGCACAAAAAGAAACATACCGGTGAATTACGAAACGTAATCGGTAAGCCACATTTATGTTCCGTATGCGGCAAACGTTTTAAATGGGctagttcgctgtcgaaacatatgaagtaccatacaaagcataagatattaaaatgtgaatattgtccaaagtactatgtcgaggcacgttctttacatattcatatgagatctcatacgggtgaaaaaccctttgtctgtcatatttgtcaaaaagcttttacacagacctgcaatttggaaaaacatttacgtgttcacactggagaaaaaccatttttatgtaatatttgtggtaaaggattttctcaacggggctacgtggcaatccatttacgaacacataccggcgaaaaaccgtacgagtgtaatgaatgtggaaaatcttttgccggttcgaatacgctggcgattcataaaagaacacacacaggaatcaaaccgtacacctgtttcgtatgctcaaaatcctttgcgcgtcaagaaaccctaataatacatcatagaacccatacgggagaaaaacctcatgtttgtacaatttgcgatcgtgccttttctagttcgggccatttatctgggcatatgcgatcgcatacaggaattaagccacacgcgtgcacaatttgtgatagaaaatttgcgggtagtagcagtcttaaagtacatatgagatcgcatactggcgaaaagccctacatttgtaattattgtggtaaggcgtttgctcagaACGCTTCGCTCTCGACACATCTTTTTACGCATGAGCCATTGCCTTCTGCGGATATATAA
Protein Sequence: MVNLSEPIEFDKICRGCMNKQIDMKPLYGSSLDEMFRTVVNVNVSMGDGLPEQMCVQCILQISRAFRFRQQCEKIDIRLRSYLEEINKLNLDVSGDFKNKGNIANDEQSDGREVKDVNSFENSSLTQINFSEAEDLPNNTGNLIFVQKIESVELHDEAQYNTNVHSEHQTIVFETNHGDNTVEDTNIDLCDAQIHILKNVKVEGLHHHTDNMLIENYETFANNMPLIVTINEENLNQSESHEIQLGEIKSLVCQLCLIDFRDADELKAHMEEVHHVLQTTFECHICNKKFGESKVLKRHLKTHSPDKPHVCLTCGMAFAEASNLTKHKKKHTGELRNVIGKPHLCSVCGKRFKWASSLSKHMKYHTKHKILKCEYCPKYYVEARSLHIHMRSHTGEKPFVCHICQKAFTQTCNLEKHLRVHTGEKPFLCNICGKGFSQRGYVAIHLRTHTGEKPYECNECGKSFAGSNTLAIHKRTHTGIKPYTCFVCSKSFARQETLIIHHRTHTGEKPHVCTICDRAFSSSGHLSGHMRSHTGIKPHACTICDRKFAGSSSLKVHMRSHTGEKPYICNYCGKAFAQNASLSTHLFTHEPLPSADI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01053660; iTF_01054586;
90% Identity: iTF_01053660; iTF_01054586;
80% Identity: -