Nscu012469.1
Basic Information
- Insect
- Nephrocerus scutellatus
- Gene Symbol
- grau
- Assembly
- GCA_947095585.1
- Location
- OX352762.1:93881993-93884641[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 9 1.5e+03 1.1 0.0 2 23 284 306 283 306 0.88 2 10 1.1 1.8e+02 4.0 0.4 6 23 315 332 315 332 0.98 3 10 3.5e-06 0.00057 21.3 1.9 1 23 338 361 338 361 0.96 4 10 0.00013 0.021 16.4 1.4 1 20 369 388 369 391 0.93 5 10 0.00012 0.02 16.5 0.3 1 23 399 422 399 422 0.95 6 10 0.012 2 10.2 0.7 2 23 429 450 428 450 0.95 7 10 0.00062 0.1 14.2 1.0 2 23 459 480 458 480 0.97 8 10 0.0082 1.4 10.7 2.3 1 23 487 510 487 510 0.95 9 10 1.3e-06 0.00021 22.7 0.9 1 23 516 538 516 538 0.99 10 10 2e-05 0.0033 18.9 4.9 1 23 544 567 544 567 0.97
Sequence Information
- Coding Sequence
- ATGATTTGCCGGCTTTGTTTAAAGGACATTGTCGAAGTCATAAGAATTTTCGATGAAATTGGAACCGAGCTAAATGTGGCCTTTCTCCTTGGAAAGTACTTTTGGTTCGAGCCCAAAATCGATGATCCCATCTCTACTGCAATCTGCAATTCTTGTTGGATCAAAGTTTCTAATTTTCATCAATTTTATGAATCCGTTGAAGAAGCTCATCGTTTACTTACGGAGCGATTTTCTATTAAATCAGTTCAAATAGCAAGCGGCAATGACGTCACAGAGAAGGACGAGCAGCAGGAAGACTCTGTGGAAGACAAGCATTTTATCCAACCCAATTGGGAATCGGATATTATTGCGAATGACGGAGGTTTACAGCTTAATGTTTTTGCTGTATCTGATGCAGCAGAATATACTAAAGATGAAAACGATATTAAACTGTGTAGTGCTAGCAGTAAAAATAAAGAAAATGCCAGCGAATTGGAATTTGCGAGTAACGAGGAACACTTTATCGAAGTAACTTTCGAGTCTGAAATGGAATCCGACAGCGACGATGACGATGTAAAACCTGTAACAGAAGAACTTATTGGAGATGTGGAGCAACGAAGAGCTTCTCTAAGATCACGGACAAGTGCAAGGGTACAGTATGATGAACAAGAGCACAGCTGTGGCGGTTCGAGTGATACGAAATCAGAAAATTTTTACAAAAACGATAGAATTCTCAATCGCAAGTCAGAAAAGTTGAGACGCAGTCCCGAAAGACCTAAATCAGCGTCTGATACGCAACACAAAAAGAACTCAAAACAAAGATGTAGATCAATAGAATGTGATGAGAAAATCGCCAAGCACATGCGTTTGATCTGCGAATTGTGTAATATAGAAGTGCCCACATTTGCTGCCATTCAACAACACTTTCAAAATGTTCACTCTCAAAAGGGCTACGTTATTTGCTGTAACAAAAAGTTATATAAGCGAATCCTGCTTATGGACCACATAAACAAACATCTAGATCCGGAGTATTTCAAATGCAATGATTGTAATAAAGTGTTTGCTGATAAGCAGTGTCTGCGTAACCATGTTCTCATAATGCACCAAGCTGATAAAGACAAAACATTCGAGTGCGAGCATTGCCCAAAGAAATTTGTGAAACGTTATCTCCTGGAGCAGCATCGTCCTATTCATGTACCAGCTGAAGAGCGAAAACATATATGCGATGTCTGTTTAAAACCGTTCCCAAATGCTACTTCCCTTACTGCCCATCAAAAGAACGTACACAACGCAGCATACGGGACAATGTGCCATATATGCGCCAAAGTAATTCGAGGTAAAGCGGCTTTCAAGAAGCATCAACTTGAACATTCGGGCGTCAAAGTACCAGAAGTGCAATGCGAAAAATGCGGCTCGTGGCTAAAAGACAAGTACAGTCTGCAAAAGCATATGCGCCGACATAACGACGAAGGAACCTTACATATTTGCTGTATATGCCGgaaggttgcgccaaatcaaagtgctctgcgaagtcattttcgttacgttcatgcttcgcagagaacttatgaatgtagtgtatgcaaaaaagcatttaaaaaaccgcttaatttaaaggagcatatgaccacacacactggggaagttctctactcgtgcccgcattgtccgaaaacttttaattccaatgcaaatatgcattcgcacagaaagaaaatgcatccgaaggaatgggaagaaaatcgaaaATATCGAAAGGGAAAAATAACTGGGAAATCGAATGAATCTTCCGATTCAATTAACGATTCGATAAATACGAGTTTAAGAAAAACTTACTCCTTCGGCACTCTTAACGAAAGCAGCGAAAAAGCAAGTGTAATGGATGTTATTATCACGGAGTACACAAGCGGTGGAGATGCTATGTACAACATTAATGCACATAAAACGTGA
- Protein Sequence
- MICRLCLKDIVEVIRIFDEIGTELNVAFLLGKYFWFEPKIDDPISTAICNSCWIKVSNFHQFYESVEEAHRLLTERFSIKSVQIASGNDVTEKDEQQEDSVEDKHFIQPNWESDIIANDGGLQLNVFAVSDAAEYTKDENDIKLCSASSKNKENASELEFASNEEHFIEVTFESEMESDSDDDDVKPVTEELIGDVEQRRASLRSRTSARVQYDEQEHSCGGSSDTKSENFYKNDRILNRKSEKLRRSPERPKSASDTQHKKNSKQRCRSIECDEKIAKHMRLICELCNIEVPTFAAIQQHFQNVHSQKGYVICCNKKLYKRILLMDHINKHLDPEYFKCNDCNKVFADKQCLRNHVLIMHQADKDKTFECEHCPKKFVKRYLLEQHRPIHVPAEERKHICDVCLKPFPNATSLTAHQKNVHNAAYGTMCHICAKVIRGKAAFKKHQLEHSGVKVPEVQCEKCGSWLKDKYSLQKHMRRHNDEGTLHICCICRKVAPNQSALRSHFRYVHASQRTYECSVCKKAFKKPLNLKEHMTTHTGEVLYSCPHCPKTFNSNANMHSHRKKMHPKEWEENRKYRKGKITGKSNESSDSINDSINTSLRKTYSFGTLNESSEKASVMDVIITEYTSGGDAMYNINAHKT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01051442;
- 90% Identity
- -
- 80% Identity
- -