Nscu018786.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nephrocerus scutellatus
Gene Symbol
zfh1
Assembly
GCA_947095585.1
Location
OX352764.1:74268491-74271484[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0012 0.19 13.4 0.1 2 23 15 36 14 36 0.97
2 16 0.042 6.9 8.5 3.7 1 23 42 65 42 65 0.93
3 16 0.0059 0.98 11.1 0.2 3 23 70 91 68 91 0.95
4 16 0.00015 0.025 16.2 0.2 2 20 100 118 99 120 0.92
5 16 0.00016 0.027 16.1 2.0 1 23 128 150 128 150 0.98
6 16 0.0048 0.79 11.4 2.5 1 23 156 178 156 178 0.97
7 16 0.0011 0.18 13.4 2.7 1 23 184 206 184 206 0.97
8 16 4.4 7.3e+02 2.1 4.0 3 22 214 233 213 233 0.91
9 16 0.18 30 6.5 0.2 1 23 611 633 611 633 0.85
10 16 0.04 6.6 8.5 3.1 1 23 641 665 641 665 0.92
11 16 0.017 2.9 9.7 1.2 2 23 670 691 669 691 0.96
12 16 0.0019 0.31 12.7 0.2 2 22 705 725 704 725 0.94
13 16 0.00037 0.061 14.9 0.4 1 23 733 755 733 755 0.96
14 16 2.2e-07 3.7e-05 25.1 1.3 1 23 761 784 761 784 0.98
15 16 5.8e-05 0.0095 17.5 1.4 1 23 790 812 790 812 0.98
16 16 5e-05 0.0083 17.7 1.7 1 23 818 840 818 840 0.97

Sequence Information

Coding Sequence
ATGCTGGTCCAAATAACAAACGATCAAAGTGGACCGAAACTAGTTTGTCCAATTTGCAGCAAAGCGTTAGTATCACTCAATGGCTATGTGAAACATATGAAAAAACACGATCCACCAGGCGGATTTCTCTGCAAATATTGTGATGATCGCTTTTGCACAGATGAGCTTTTAAAGAAGCATCGTCAAGAGACTCATTCGACTCTTGCATGTCGCCTATGCCATGAGACATTTCCAGCAGCTGAGGATTACCGCGAACACATTCGTATTCGTCATAACGGAATCGATCGTGAGATGTCAGTTTGCACCAAGTGCGGTGTGGAATTTAAGACAAAAGAGGCACTTAAGCGTCATGAATCCACACAATGTGGTCAAATAAAACCGCATAAGTGTGATCAGTGTGACATAGCATTCTATACCATTTATAATCTAAAGGAGCACAAGAAAATCCATAGTGGCGAGAAGAAATTCTGTTGCAGCTACTGCGGAAAAAATTTCCTTCAAAAAGGCCGCTTGGTGGTACATGAGAGATCACATACAGGGGAGAAACCCTACAAATGTGATGTTTGTGCGAAATGTTTCGCTCATCGTGAGAGTTTTGTAACACATGCATCAATTCATACTGGAGTAAAGCTAGTCATTTGTAAGTGTTGTGATGCGCGATTCTCTTGCTATTCGAATCTCATTAAACATAGACGTTCACGACCCGATACTTGTGGTTTAACTATTTACGATCCGTCTAAGGATGCTGTACGTACAGGAAAGTCAAGAATTCCAGCATCACTTATGACATCAGAAATTCGTATAAGTAATGCCAGTAAGATAATCAAACCATCAGAAACACAAAAAATACCAGCACATGTCGCTAAAATTGAATCAATTTCAAAAGTGGACTTGTCAGGATTACCTTCATCAGATGTTGATAACATGGATCATACAAGAAAGCATGAAGACACGAAATCGGGACAACTTTCTGAAAAAATTGACAGTACCTCCAGCAAAATAGTATCACCGCAAATAACTTCTAATAAGGAAGATAAATCATCCGATGATACTGATGATTCAGAAGACGACTATCCCGATTTTGATCCTCCTGATAATATAAATGACGATAATGATTCAGATGATGTTAAATTGCCAGAACCAAAACTGGAAATTGTTATTAAGGAGGAAAACCCCGCCGAATTTGATACTTTAGATACAAATTTTCTGCCAAATGACTTAAATGTAAAATCGGAAAATAATGAAAATAACGCTGATTTGAACGCTTTCGTCGATAAAGATCAAATTCTGGATGCTCTACTAATGGAGAACTCACCAGACTCAGCCAAATTACTTAATTTTCATAGTATAAAATTAGAAGAATTATGTCGAGAAAATGTGGGGGAGGAAATCAAAGTCGACGATGATGCATTGGCAACAAGTGAGCATTCAGATGGTCTCCAAGAATGCACACTAGTTATAGAAGATGTTTGCAATCGTTACCCACAGCTTAAAACGGATAAAACTATTAAACTTTCTCAAAATACAAAGTCATTAGCACCAGTAAACAAGAAGCAGAAACCGCAAAAAAAGGAACACGTTTCACCAAAACTACCATCACAACCGCGAATGTCCTCCACACCATTGATCCGTCGTATATATCAATCAGAACTAAAGCAACGTATGAAACTAATGAAGAAGGATAAAACATATGAATGCATTGATTGCATTAAAGTTTATCATATCCGCAAGCCATACGAAACCCATTTACGAGAATATCACAAGAAAACCGATCTGGAACTGAGGGAAATTTTTAAAGATGAGGAGGATGAGCTACTTGACAATATAGTTTTTAAATGTCCGATTTGCTCTAAAATTTATTTGATAGAAAAACGACTCCAGTCGCATATTATCCTGCATGGACCTAATGGTATTCTTGTCCACAAATGTCCGTGTTATTGCACAAAATTTTTCGCCACTAAAGAAGAAGCATTTGAACATGCCAAGGCCGAACATAAAGAACTGATTTATTGTAAATTATGTGATAAATTCAAAAACACTCCAGATGGGTTTAAAACTCATATGCTAAAGCATGCGCCAGATAAAAAACCACGAGTTATTAAGAGGAATCTCGTATGTGACAAATGCGCTAAAAAGTTTGCCAGTCGAACTTCTCTTATCGACCATACACGGTCGGATTGTGGTCGTAATCCAATTTATCAGTGCGAAATATGCGAAAAACGATTTACCTCAGCTGGCATTCTGAAGACTCACAAACTTCTGCACAAGGACGAGACACCTTACCAATGCGATCAATGTGGGAAAACCTTTAAAGTGAAAGCACAATATATGGCGCACATGAAAACGAGACACACAGATTACAAACCGTTTAAGTGTCATCTGTGTCCCAAAGAGTATCCGTACAGAGAAAGCCTTCTCACGCACATGACAGTTCATACCGGATTTAAGCGTTTCGCTTGCAACGGTTGTGGCAAACGTTTCACTTGCATTTCAAATCTTCAAGCCCATCGAAAGGTTCATGCCGATACTTGTGGTCTTCTGCCGTTAAATGCAAAGGCCAGCCAATACATGGGTGTGCAGAAGGGTGTGCTTTTAGTCGGGACAAAGCCGGAAGCTGGACTGGAATAG
Protein Sequence
MLVQITNDQSGPKLVCPICSKALVSLNGYVKHMKKHDPPGGFLCKYCDDRFCTDELLKKHRQETHSTLACRLCHETFPAAEDYREHIRIRHNGIDREMSVCTKCGVEFKTKEALKRHESTQCGQIKPHKCDQCDIAFYTIYNLKEHKKIHSGEKKFCCSYCGKNFLQKGRLVVHERSHTGEKPYKCDVCAKCFAHRESFVTHASIHTGVKLVICKCCDARFSCYSNLIKHRRSRPDTCGLTIYDPSKDAVRTGKSRIPASLMTSEIRISNASKIIKPSETQKIPAHVAKIESISKVDLSGLPSSDVDNMDHTRKHEDTKSGQLSEKIDSTSSKIVSPQITSNKEDKSSDDTDDSEDDYPDFDPPDNINDDNDSDDVKLPEPKLEIVIKEENPAEFDTLDTNFLPNDLNVKSENNENNADLNAFVDKDQILDALLMENSPDSAKLLNFHSIKLEELCRENVGEEIKVDDDALATSEHSDGLQECTLVIEDVCNRYPQLKTDKTIKLSQNTKSLAPVNKKQKPQKKEHVSPKLPSQPRMSSTPLIRRIYQSELKQRMKLMKKDKTYECIDCIKVYHIRKPYETHLREYHKKTDLELREIFKDEEDELLDNIVFKCPICSKIYLIEKRLQSHIILHGPNGILVHKCPCYCTKFFATKEEAFEHAKAEHKELIYCKLCDKFKNTPDGFKTHMLKHAPDKKPRVIKRNLVCDKCAKKFASRTSLIDHTRSDCGRNPIYQCEICEKRFTSAGILKTHKLLHKDETPYQCDQCGKTFKVKAQYMAHMKTRHTDYKPFKCHLCPKEYPYRESLLTHMTVHTGFKRFACNGCGKRFTCISNLQAHRKVHADTCGLLPLNAKASQYMGVQKGVLLVGTKPEAGLE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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