Nign019825.1
Basic Information
- Insect
- Neoneuromus ignobilis
- Gene Symbol
- topi
- Assembly
- GCA_029203775.1
- Location
- CP092093.1:33361259-33366370[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00076 0.061 14.6 1.3 2 21 147 166 146 167 0.94 2 13 4.8e-06 0.00039 21.5 2.3 1 23 191 213 191 213 0.98 3 13 0.00039 0.032 15.5 0.2 1 23 219 241 219 241 0.97 4 13 0.022 1.7 10.0 4.4 1 23 429 451 429 451 0.98 5 13 0.58 47 5.5 0.6 1 20 457 476 457 478 0.91 6 13 0.0063 0.51 11.7 1.2 2 21 494 513 493 517 0.88 7 13 0.032 2.6 9.5 0.3 1 23 858 881 858 881 0.98 8 13 0.055 4.4 8.8 1.5 1 23 885 907 885 907 0.92 9 13 7.4e-06 0.0006 20.9 3.2 1 23 913 935 913 935 0.98 10 13 0.049 4 8.9 0.2 1 23 941 966 941 966 0.96 11 13 0.088 7.1 8.1 2.3 1 23 972 994 972 994 0.85 12 13 5.5e-06 0.00044 21.3 0.3 3 23 1002 1022 1000 1022 0.98 13 13 2.1e-06 0.00017 22.7 0.6 1 23 1028 1051 1028 1051 0.98
Sequence Information
- Coding Sequence
- ATGAACGAAAATGACAATATCTTTTTAAAGGTGAATCAAATGGACGCAGAGAATTTACATGACATTAATACTGACAGTATTGtacataatcaatttttacCACACGGTTTAATGTCATCGGAAGATGTAAAATTCGACGAAACGTCGTTGCAATGGGGATACGTAATCGACACGGACTCAAAACTAGATATAAAACTGCACAACAATGAAACGAAACCGGCAACAATTACGTTCATAAAAATCGGCGGAATCGAAGATCTAAATCCGCTAAACGATTTAAATAACATGACACCGCCTCTGAATCCATTCCATCAGATGATCGTCCCGAACAGTTTTATAAACCAAACTCTAGACGATACAACAATACCCGTCACGAAAATCAAAGAGAAggtcaaaaagaaatattacccGCCAGTGACACAGACCGAACCGATTGTTACGTGTCAAAACTGCGATGCTTCGTTCGTAACAAAGTATCAGTACCAGAGACACCAATGCGAGTTCAACGCGTCGAAAGTTATTTTGAAGACCGAGTTACCGAAACGGCATATCGAAAAGCCGAAAACGAAATACGAGTGCGAGGTTTGTCATAAATCGTTCATGACTGAATATAATCTCGAAAGGCATCGTCTCTCGCATGGCGACACGAAACCGTTCACGTGTGAGAATTGCGGCAAGGGGTTTGTGCTCGAATCCCGTCTCAATTCGCACATCGAAAATCATTGTAAATTGTCTGGCgacactaaaaaatattacaagaccGGACTTACCGTGTGGCAATGTTGGAACTGTAAActgataacaGCCACTGAACCTAATACAAACGTCCACATTTGCGATAATATAAATCCGACATTTATtccaaataaaatcgatatgtCGCGACTGACTCTACCGTCACTGAACGATCccgaagaaaataaagaaaacgtCGATCCAAACACACAGTGGTATAAAGAGAACATAAATACCAATTTTATAGAATTCAAGGACTTGTCGAATAATCTCGTTTATGAGAACCCATCGCCGATTATAAAAGTGTTCGGCGAGCACAATTTCAATGCGGATTTATCTTTGAGAAACGAATTTGCATTCCCTCCTCGACCCGATGTGCCGATGGAAAATAATTTCGATACGAGTTTCGAAAAAGCCATCCACGGCATCGACAGTTATCCAAGCGAGCAGCCGTTTTACAGAGGAGAACCTCCGCAAAGAATCCACGTGAATACCGAAGAGTATCAAGCTCTTCCGCacacgtttaaaaaaacgatcGTCGAACAATTGTTCCAGTGCGAGTACTGTAATCGTACTTATTCCGAGAAAGACACGCATAAAGATCATCAGAATTCGCACAAGactgataaaaattatgaatgtatGTTTTGCGATGAATACTTTAAGAGTTACACGAACGCTGTTGTCCACTGGCAACACAAATGTGATAACAAGATGAATCTCTTTTGTTTACCGAAAATTATCGTATGCAAAATCTGCGAAAAAGGATTTAAGTCGCATGAGCTTTTATACGCACACAAGTATAAACTGAAACATTTTATACCGAAGTTGCACAACGAAATTgacaataaacattttcaaatagaaaatatgaaaaatatcataacGCACGATAACGAAATCGCCGATAATACTGTTTTGAACGATCCTCTATCGAATACCAGCAAAGAGAATTTCGATGTAGACAAACTGTCTGAAAATGTAGAAATATCAGATTTATACAAATCGAATAATGTGACCGTACAAAGTTTGAACACGACCACGTCAGATTTAGATTTGGATTCTAGTAAGAATCAAAACATCGACGACATTTTAACAGAAATCGATTCGGAGATCCGAGATGATAAAAACAATTGTAAGAATCTTCCGATCGTCACAAACGAGCCAAACATCGATATCAATAGCAAAGaagtaaatagtttaaatatcgATAACGTCGATGATATCGATCAGCTTGATCAGTTTTTGAACGATATCGAACAAAAAGTCCTGACACAGAAACGTTTAAGTGAAATGAATATCTACGAGAGCGAAACAACTAGACAGAATGTTTCTAAAACGAATCCCGTTGAAGATTCCGGAAGAAGAGTACTCCGGAGTAGTACCAGAAAGACTATAAACAGTCCCGTTAAGAACGCCGATGAGAGTAAAAAAGATGGACCGGTTACGGAATCATTGAAGGTCAGTTTGAAAATGCCCAGTGTGCAGCTGGTTCGATTGAGCTgtgaacaaattgaaaaaagtacaaaGTCATCGATCGATAAAACAATAACAGAAAAAGACTTGTCGAAAAAAGCTGTAGATAAGATCGAACTAGCATCTTTAAAAATAGAGAAGGTCGATGTAAAAGATACGAACATCGTAGAAGAGAATAATTTGAAAAGGAAATCTAAGGATAAAGTGGAAATTAAGAATGAACTCGATGTTCTTCATGACGACGTCCATGCGAAAGAGGAACCGCCTGTTGCGGTACCGGTGCCGGCCAAACGGGGTAGAAAACCGAAACCGAAGTTCCCTGTCGAACAGATTGTGAATAAATGCGAAGAAGGGTATCGTTTCCAGTGCGAGAAGTGTGCGAAAGTCACAATGACCATTAATGAATTGCTCGAGCATAGACAAACAGAACATGGAAGTAAATACGATTGTAAAGATTGCGGACagGTGGTTCATAGTTCAAAAGCTTTAATGATCCATTGCAGAGCACATCAGAGCTTAAAACCTTATGTATGCGATCAGTGTAATCGTAGTTATTCCCAAACTTCTCATCTTTGGCAACACATGCGTTTCCATCAAGGAATTAAACCATTCGCATGTCCTCATGAGGGCTGCGAGGCACGTTATACAATTAGACCAGATTTGAAAGACCATATCCGAAAAGTTCACACCCGTGAAAGACCTTTCCAGTGTTCAGTATGTGGAAAATGTTTTCTTACTGGATCTGTATATTACCAACATCGGCTTATTCATAACAATGACCGGAGATATGGATGTGATATATGTGGTAAACGGTTTTTCCGAGCAGACGCTTTGAACAACCATCGTCGCATTCATACCGACGAACGACCTTTTCCTTGTCCGGTTTGTGGAAGGGAATTTCGTCAGAAAGGTGACAGGAACAAACACCAACGTACGCAGCACCCGACAAGTTTTATTGTTCCAAATCCTAATATTGAAACTAAAGTGTGA
- Protein Sequence
- MNENDNIFLKVNQMDAENLHDINTDSIVHNQFLPHGLMSSEDVKFDETSLQWGYVIDTDSKLDIKLHNNETKPATITFIKIGGIEDLNPLNDLNNMTPPLNPFHQMIVPNSFINQTLDDTTIPVTKIKEKVKKKYYPPVTQTEPIVTCQNCDASFVTKYQYQRHQCEFNASKVILKTELPKRHIEKPKTKYECEVCHKSFMTEYNLERHRLSHGDTKPFTCENCGKGFVLESRLNSHIENHCKLSGDTKKYYKTGLTVWQCWNCKLITATEPNTNVHICDNINPTFIPNKIDMSRLTLPSLNDPEENKENVDPNTQWYKENINTNFIEFKDLSNNLVYENPSPIIKVFGEHNFNADLSLRNEFAFPPRPDVPMENNFDTSFEKAIHGIDSYPSEQPFYRGEPPQRIHVNTEEYQALPHTFKKTIVEQLFQCEYCNRTYSEKDTHKDHQNSHKTDKNYECMFCDEYFKSYTNAVVHWQHKCDNKMNLFCLPKIIVCKICEKGFKSHELLYAHKYKLKHFIPKLHNEIDNKHFQIENMKNIITHDNEIADNTVLNDPLSNTSKENFDVDKLSENVEISDLYKSNNVTVQSLNTTTSDLDLDSSKNQNIDDILTEIDSEIRDDKNNCKNLPIVTNEPNIDINSKEVNSLNIDNVDDIDQLDQFLNDIEQKVLTQKRLSEMNIYESETTRQNVSKTNPVEDSGRRVLRSSTRKTINSPVKNADESKKDGPVTESLKVSLKMPSVQLVRLSCEQIEKSTKSSIDKTITEKDLSKKAVDKIELASLKIEKVDVKDTNIVEENNLKRKSKDKVEIKNELDVLHDDVHAKEEPPVAVPVPAKRGRKPKPKFPVEQIVNKCEEGYRFQCEKCAKVTMTINELLEHRQTEHGSKYDCKDCGQVVHSSKALMIHCRAHQSLKPYVCDQCNRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFQCSVCGKCFLTGSVYYQHRLIHNNDRRYGCDICGKRFFRADALNNHRRIHTDERPFPCPVCGREFRQKGDRNKHQRTQHPTSFIVPNPNIETKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00004887;
- 90% Identity
- -
- 80% Identity
- -