Nign029532.1
Basic Information
- Insect
- Neoneuromus ignobilis
- Gene Symbol
- wdr45b
- Assembly
- GCA_029203775.1
- Location
- CP092098.1:4817484-4828019[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.0092 0.74 11.2 0.5 1 23 556 578 556 578 0.98 2 14 0.88 71 5.0 5.5 1 23 606 628 606 628 0.96 3 14 0.0083 0.67 11.3 4.2 1 23 634 656 634 656 0.95 4 14 0.0077 0.63 11.4 0.3 1 23 663 685 663 685 0.96 5 14 5.7e-05 0.0046 18.2 4.2 1 23 691 713 691 713 0.99 6 14 3.9e-05 0.0032 18.6 1.1 1 23 719 741 719 741 0.99 7 14 0.00048 0.039 15.2 2.6 1 23 747 769 747 769 0.99 8 14 0.00019 0.015 16.5 1.2 1 23 775 797 775 797 0.96 9 14 0.0052 0.42 12.0 1.0 1 23 804 826 804 826 0.97 10 14 0.00091 0.074 14.4 1.4 1 23 832 854 832 854 0.98 11 14 5.9e-05 0.0048 18.1 1.2 1 23 860 882 860 882 0.96 12 14 0.00087 0.07 14.4 0.3 1 23 889 911 889 911 0.97 13 14 5.6e-06 0.00045 21.3 1.2 1 23 917 939 917 939 0.98 14 14 0.0055 0.45 11.9 0.5 1 23 954 976 954 976 0.97
Sequence Information
- Coding Sequence
- ATGAATTTATGTACAGAAAATCCTTACGATAATGGTTTATTATTCGCTGGCTTTAACCGAGAtcgaGATGTTTTACTTGTGCAACTGAATCGGGTTTTCGACTACGTTGAAATGCTTTTTCGTCGTAACTACTCAGCTCTTGTCGGTGGAAGTAAAAGATCAGTTTATCCTCCTAACGGAGTCATTATTCgggatgatttaaaaaagcaacCGACAATATCGTTAGAATTTTCTACTCCTGGTAAAGCAGTACGATTGAAAAGAGACAGAATCGTTGTCGTTCTAGaaggtgttattaaagtatatacatTCACTTCTCAACGATTACACATTTTTGAAACAAGTCCAAATCCGAAAGGTCTTCGTGCACTTTGTCCTAACAGTAGTAATAATTCACTTTTGGCATTTCCCGATTCTGATGATAGTGACCAACAAACTGAAACTGCTGTTGATAGAACTATGTGGAAAAAGATCAAACATAAATCTACTCCGTTTCTAAGAAGACCACAGCGTAGAACCACTTTCAAAGGAGTTAGCGGTCCTACAGCATATGCAAAAAGAAACATAATCGGAGTATATGTAGACGACGAAATAGTCATAACTTCGTCTGTAAAGCTCAAGGACGAGCTATTAAGATTACTAAGAATTCAACTCGAGATAAAGAAACTCGGAACGTTTCAATTCTTTTCGAACATAGAAGTGTCAAACGACAATGAGAACAGCATCGTGTATTTAAACCGAACAAGCTACGTTAAACAAATTCTACGAAGATTCAATATGTCAAATCGTAATTCAGCGATTACACCGTTAAATGAAAATCAGAAGCTGagtgaaaaacaaaaatattcagataCATGCAACAGTTCAGAATCAAGTGATTTTCCATATCGGGAGGCAGGGGGGGGGCACAATTTTGTACATAAGCCAAACAGCAAGAAACGTTTTGTACCTATTTTAGCAATGAATATAACAAATGTTCATGATTTGCCGAGCTTATGTAGAACATGTTTATCGCAACATAACAACGCTTCTGACATATTCAGTGGAAAATGTGTCAACGAAAAAACGTTCAGTGAAGTCTTAATGGAATACGCTTCGATACAAgttTGTAAGAATGAAAGATTATCGCTGTTCGTCTGCCATTCATGTGCTGAGTATTTGAAGACGTTCGCTGTTTTCCGCAATAAATGTATCGAAACAGAGTCTGCATTATGTGATTTCCTTCGAGATTCGCGCTTCGACATAGAAGTAAAAAAGGAACCGGGAAATAATGTAACAGACATCGATAAAGATTGTAGTTTTTCCATGcaggaaaaaatatcttttcgacGATGTTTACGAACCGATATCGATTCGTGCGCAAAAAACGTCGATGAACCGAACATCGTAAAAGTTAAAATCGAAGTAGACGATGAAGAAACTAATGACGAGAGAACGCAGTCATGTTTTTCTACATCGTACGAGAGAGGATCGGATGAAAATCTCAGAACGTATTTTTCTTTACAAGAATCGATCGATATCAAAGAGGACATCGAGGATTTTGTCGACGATGAGAACACGACGTCGGAAGTACCGAACGACGCAAGAGAGACACGCGCGACGGATTCGGACAACTGGGAAGATCAGTCATTAGAAAGTAGAAGAATTCGTTCAGGTCACGATTCGTTCACTTGCGACTCGTGCAATGGGTCGTTCGCGACGAAGACACGTCTCGacgtacatttaaaaatacactgcGAAGGAAAAGAAGATCTCGGCGCGACGAAGTCGTACCATCGACGAACGACTAAGAACGTCGACGTCTCCGATAGACCGTTTCCATGCGATCGATGCAAAATGTCGTTCTTGATGAGACATCAGTTACACAAACATATGTACCTCCATACTGGCGAGAAGCCGTTCAAGTGTGACACGTGCGTCAAGTCGTTCTGTAGTAAACAAAATTTAGACCTACACTCCTACATGCATTCCAAAATAAAGAGACCGTTCGCGTGCGATCTGTGCACGAAATCGTTCTTCACCACCGAGCGTCTGGCCGCGCACAAGATCGTGCACCTCGGCAAAAAACCGTTTAAATGCAACGAATGCGATAAGTCGTTTTCGTGCAACACATTTTTGGTCCGGCATATGAGAGTTCACACGGGTGAAAAACCTTTCAAGTGCGATGAATGCGAAAAGTTGTTTTCGTTCATTTCGAATCTAGTCCGGCATAAGAGAATTCACACGGGTGAAAAACCTTTCAAGTGcaacgaatgcgaaaagtcgttttcgtgCAACAGAGTTTTGGTCCGGCATATAAGAGTTCACACGGGTGAAAAACCATTCAAGTGCGACACGTGCGGTATGTCGTTTGCTCAGAAAAATACATTAGACCGACACTCCTACatgcattccaaaaaaaagagaCCGTTCGCGTGCGATCTGTGCACGAAATCGTTCTTCACCACCAAGCGTCTGGCCGCGCACAAGAACGTGCACCTCAGCAAAAAACCGTTTAAATGCAACGAATGCGAAAAGTTGTTTTCGTACAACTCGATTTTGGTCAAGCATAAGAGAGTTCACACGGGTGAAAAACCGTTCAAGTGCGACACGTGCGGTATATCGTTTGCTCGGAAATATACATTAAACCTACACTCCTACatgcattccaaaaaaaagagaCCGTTCGCGTGCGATCTGTGCACGAAATCGTTCTTCACCACCGAGCTTCTGGCCGCGCACAAGAACGTGCACCTCGGCAAAAAACCGTTTAAATGcaacgaatgcgaaaagtcATTTTCGTCCAAACCAAATCTGGGTCAGCATAAGAAAGTTCACACGGACCATCACTCCTacgtgcattccaaaaaaaaaagacCGTTCGCATGCGATCTGTGCACGAAATCGTTCTTCAGCACCGAGCGTCTGGCTGCGCACAAGAACGTACACCTTGACAAACTACCGTTCAAGTGCGACATATTACAGCATCCAAAAGGGCATTAA
- Protein Sequence
- MNLCTENPYDNGLLFAGFNRDRDVLLVQLNRVFDYVEMLFRRNYSALVGGSKRSVYPPNGVIIRDDLKKQPTISLEFSTPGKAVRLKRDRIVVVLEGVIKVYTFTSQRLHIFETSPNPKGLRALCPNSSNNSLLAFPDSDDSDQQTETAVDRTMWKKIKHKSTPFLRRPQRRTTFKGVSGPTAYAKRNIIGVYVDDEIVITSSVKLKDELLRLLRIQLEIKKLGTFQFFSNIEVSNDNENSIVYLNRTSYVKQILRRFNMSNRNSAITPLNENQKLSEKQKYSDTCNSSESSDFPYREAGGGHNFVHKPNSKKRFVPILAMNITNVHDLPSLCRTCLSQHNNASDIFSGKCVNEKTFSEVLMEYASIQVCKNERLSLFVCHSCAEYLKTFAVFRNKCIETESALCDFLRDSRFDIEVKKEPGNNVTDIDKDCSFSMQEKISFRRCLRTDIDSCAKNVDEPNIVKVKIEVDDEETNDERTQSCFSTSYERGSDENLRTYFSLQESIDIKEDIEDFVDDENTTSEVPNDARETRATDSDNWEDQSLESRRIRSGHDSFTCDSCNGSFATKTRLDVHLKIHCEGKEDLGATKSYHRRTTKNVDVSDRPFPCDRCKMSFLMRHQLHKHMYLHTGEKPFKCDTCVKSFCSKQNLDLHSYMHSKIKRPFACDLCTKSFFTTERLAAHKIVHLGKKPFKCNECDKSFSCNTFLVRHMRVHTGEKPFKCDECEKLFSFISNLVRHKRIHTGEKPFKCNECEKSFSCNRVLVRHIRVHTGEKPFKCDTCGMSFAQKNTLDRHSYMHSKKKRPFACDLCTKSFFTTKRLAAHKNVHLSKKPFKCNECEKLFSYNSILVKHKRVHTGEKPFKCDTCGISFARKYTLNLHSYMHSKKKRPFACDLCTKSFFTTELLAAHKNVHLGKKPFKCNECEKSFSSKPNLGQHKKVHTDHHSYVHSKKKRPFACDLCTKSFFSTERLAAHKNVHLDKLPFKCDILQHPKGH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -