Basic Information

Gene Symbol
-
Assembly
GCA_029203775.1
Location
CP092087.1:19314701-19318632[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 2.6 2.1e+02 3.5 0.2 13 23 71 81 69 81 0.91
2 20 2e-07 1.6e-05 25.9 0.4 1 23 87 109 87 109 0.98
3 20 0.0014 0.11 13.8 4.3 1 23 115 138 115 138 0.97
4 20 0.0025 0.2 13.0 0.6 1 23 167 189 167 189 0.95
5 20 0.0021 0.17 13.2 0.1 1 23 194 216 194 216 0.92
6 20 4.2e-07 3.4e-05 24.9 0.8 1 23 222 244 222 244 0.99
7 20 5.3e-06 0.00043 21.4 4.2 1 23 250 272 250 272 0.98
8 20 1.2e-08 9.4e-07 29.8 0.7 1 23 278 300 278 300 0.98
9 20 1.7e-06 0.00014 22.9 1.2 1 23 306 328 306 328 0.98
10 20 0.00041 0.033 15.5 2.2 1 23 457 481 457 481 0.93
11 20 0.89 72 4.9 0.3 2 23 487 507 486 507 0.92
12 20 0.00018 0.014 16.6 0.8 1 23 513 535 513 535 0.98
13 20 1.7e-06 0.00014 23.0 0.2 1 23 541 563 541 563 0.98
14 20 0.006 0.49 11.8 1.2 6 23 573 590 571 590 0.96
15 20 0.0064 0.52 11.7 1.5 1 23 621 643 621 643 0.96
16 20 0.00048 0.039 15.2 1.5 1 23 648 670 648 670 0.95
17 20 8.6e-07 7e-05 23.9 0.7 1 23 676 698 676 698 0.97
18 20 8.7e-08 7e-06 27.0 3.1 1 23 704 726 704 726 0.97
19 20 6.5e-07 5.3e-05 24.3 0.8 1 23 732 754 732 754 0.98
20 20 2.9e-05 0.0024 19.0 1.3 1 23 760 782 760 782 0.96

Sequence Information

Coding Sequence
ATGTCCAATGAAATAACAAgtttaagtataaataaagtATGCCGTACTTGTTTAGCTGTAGGggatttaaaatctatttttattgagAGTTCAAAATCGGTACCTCTATCAGAAATGATAATGGCATGTGCTTCAAttaagataacTGAAAATGATGGCCTCCCTTCTCAAATATGTACTACTTGTTTCCAACAAGTTACTGAAgcTTTGAGTGGAAATTTACGTCGTCATGTTATGACTCACACTGGAGAACGACCTCATCAGTGTAAAATATGTGGAAAAGGATTTATTCAAGCAGTATCATTGGAAACCCACATGCGTGTTCACACAGGAATAGCTCcttttgtttgtaatttttgtgGAAGAGCTTTTAAGCAATCCAAACAATGCcaaattcatatgaaaaataaacacattgaaCCGTCAGAACCAAATGATCGACGAAAACGGCCAGTTTCACAAATTTCAAGAAAATCATCAGATGATGTTCTTAGACCGTTTGTTTGCAATATATGTCAACGAGCGTTCACCACAAAAATCATTCTACAGACACACTCCTTACGCCATggtgaaaaaacatttttatgtagtGAATGTGGAAAAGGTTTTGTTAGTAAAGTAGGACTGGACAGTCATAGCATTGTTCATTCTGGTATCAAACCATATCAGTGTAACATTTGTACGAAATCATTTGCCTATAGTGGTTCTCTTAAAATTCACATGTTAAAACATACAGGAGAAAAACCATATAGTTGTGATTTATGTAGCAAACGATTTACTCAAAGTACTCATTTAAAAACTCATATTCGATTACACAAGGGAATTAAACCATATAATTGTTCAGTGTGTGGAAAAGATTTTTCTCAAAAAGGAAATTTAACTGTTCATATGAGAACACACACAGGAGAAACACCATTTGTATGTCCTGTTTGTGGAAAAGGATTTTATGATTCTAGTAGTATGAGAAAGCATCATAGAGGTCATATaaataaGAGTGATGTAAAAACAGAATTGCTACTTTCAGAGATATTAATGGAGTGTAGTTCAATTGACgTTGTGGAAGGAGATGGATTACCCATTCATATGTGCACTAACTGCATTAAAGAAATGACTGGTGCTTATCAATTTCGGCAATTATgtattaaatcaaatacaacACTTCGTTCTTACATTAACATTCAGAAGTTTTctgatagtaaaaataaattgaagttaTCTCTTGATAACCAATCAAATAGTGATGTAGAAATAAATGAATCCAATAATATACTCGTAGATGAAGATTCTACTTATAATAttaaaaaaactacaaataatTCTAAACAAGTAAAAAGTAAACCTCGAAAGAGAAAATCCTCTCATcctatttttaaatgtagaaaATGTAAAGAAGTTTTCTCATCTGAAGTTGAATTAAAAGAacatacaaaaacaaaaaaacatcCAGATCGTCAAATACCATGTACTGTTTGTTCAAAATTGTTAGGTTCTAGAAACATGTATATTCATATGAGAACTCACACCAAAGAAAAGCCATATGCTTGTAGTTTTTGTAATGCTCGTTTTAGTGCAAATGGAAATTATCGACGTCATTTAATGACACATACAGGGCAGCGACCACATAGATGCGGTGTTTGTGATAAAGGTTTCATAAGAGCAGTATCATTAGAATGGCATATGCGTGTTCATACAGGAGAAAGAccttttgtttgtttttgtggAAAAGCATACAAACagtcaatacaattaaaaacacatgcaaaaaaacatattcaatcAGAAGATAAAAGCGATGAAAAATCAGAAAATGATTCATCACGACGGACAAAAACCGGTCGTCTAGATGATGCAGAGAGAACACACATATGTGAAATTTGTAAAAGGGGTTTTACTACCAAAATGATATTGTCAACACATTTGTTAACACATGGAGATAAGAAATTTTTATGCAGTGATTGTGGAAAACAATTTCATACAAGAATGGGGCTTGACACTCACATTAAGGTTCACAATGGGAAAAAGCCTTACATTTGTAATATATGTGGAAAAACATTTGCATATAAAGcatctttaaaaaaacacacttaTGTTCATACGGGTGAAAAGCCATATGCCTGTAAAATTTGTGATAAAAAGTTTTCACAAAGTAGCCATTTAAGAACTCATATTCGACTTCATTCAGGAATCAAACCATATAGTTGTTCAATATGTAgcaaaaattttacattaaaaggCAATCTAACAGTACACATGAGAATTCATATGGGGGAAAAACCTTTTACGTGTATTGTTTGTGGAAAAGGTTTTTATGATTCGagtagtttaaaaaaacatcgtaATAGACACGGAGATAAAACAGTTCagaatttatttacatcaacaaACATTACCTCCACTTAA
Protein Sequence
MSNEITSLSINKVCRTCLAVGDLKSIFIESSKSVPLSEMIMACASIKITENDGLPSQICTTCFQQVTEALSGNLRRHVMTHTGERPHQCKICGKGFIQAVSLETHMRVHTGIAPFVCNFCGRAFKQSKQCQIHMKNKHIEPSEPNDRRKRPVSQISRKSSDDVLRPFVCNICQRAFTTKIILQTHSLRHGEKTFLCSECGKGFVSKVGLDSHSIVHSGIKPYQCNICTKSFAYSGSLKIHMLKHTGEKPYSCDLCSKRFTQSTHLKTHIRLHKGIKPYNCSVCGKDFSQKGNLTVHMRTHTGETPFVCPVCGKGFYDSSSMRKHHRGHINKSDVKTELLLSEILMECSSIDVVEGDGLPIHMCTNCIKEMTGAYQFRQLCIKSNTTLRSYINIQKFSDSKNKLKLSLDNQSNSDVEINESNNILVDEDSTYNIKKTTNNSKQVKSKPRKRKSSHPIFKCRKCKEVFSSEVELKEHTKTKKHPDRQIPCTVCSKLLGSRNMYIHMRTHTKEKPYACSFCNARFSANGNYRRHLMTHTGQRPHRCGVCDKGFIRAVSLEWHMRVHTGERPFVCFCGKAYKQSIQLKTHAKKHIQSEDKSDEKSENDSSRRTKTGRLDDAERTHICEICKRGFTTKMILSTHLLTHGDKKFLCSDCGKQFHTRMGLDTHIKVHNGKKPYICNICGKTFAYKASLKKHTYVHTGEKPYACKICDKKFSQSSHLRTHIRLHSGIKPYSCSICSKNFTLKGNLTVHMRIHMGEKPFTCIVCGKGFYDSSSLKKHRNRHGDKTVQNLFTSTNITST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-