Basic Information

Insect: Neoitamus cyanurus
Gene Symbol: Ctcfl
Assembly: GCA_947538895.1
Location: OX384540.1:22534228-22536466[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.016 2.3 9.7 4.5 1 21 188 208 188 210 0.95

2 11 9.2e-06 0.0014 19.8 1.3 1 23 216 238 216 238 0.98

3 11 0.0036 0.53 11.7 4.2 1 23 244 267 244 267 0.95

4 11 0.007 1 10.8 3.5 1 21 273 293 273 295 0.95

5 11 0.00011 0.017 16.4 1.9 1 23 301 323 301 323 0.99

6 11 1.3e-05 0.0019 19.4 1.2 1 23 329 351 329 351 0.98

7 11 0.00029 0.042 15.1 1.4 1 23 359 382 359 382 0.97

8 11 0.00073 0.11 13.9 3.6 2 23 389 410 388 410 0.97

9 11 0.00026 0.038 15.3 0.2 1 23 416 438 416 438 0.98

10 11 6.9e-06 0.001 20.2 2.6 1 23 444 467 444 467 0.96

11 11 2.3e-07 3.4e-05 24.9 1.4 1 23 481 503 481 503 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.016	2.3	9.7	4.5	1	21	188	208	188	210	0.95
2	11	9.2e-06	0.0014	19.8	1.3	1	23	216	238	216	238	0.98
3	11	0.0036	0.53	11.7	4.2	1	23	244	267	244	267	0.95
4	11	0.007	1	10.8	3.5	1	21	273	293	273	295	0.95
5	11	0.00011	0.017	16.4	1.9	1	23	301	323	301	323	0.99
6	11	1.3e-05	0.0019	19.4	1.2	1	23	329	351	329	351	0.98
7	11	0.00029	0.042	15.1	1.4	1	23	359	382	359	382	0.97
8	11	0.00073	0.11	13.9	3.6	2	23	389	410	388	410	0.97
9	11	0.00026	0.038	15.3	0.2	1	23	416	438	416	438	0.98
10	11	6.9e-06	0.001	20.2	2.6	1	23	444	467	444	467	0.96
11	11	2.3e-07	3.4e-05	24.9	1.4	1	23	481	503	481	503	0.96

Sequence Information

Coding Sequence: ATGTCTGCGAAAGTGGCGGAGGTAACAGAAGTGAAAGTCGAGAATACAAACGACTTACAGTCGTACTTGGAGTCATTTAATCAGGAGATAGATGATGGAAGCGGCACAATCCAAATCCTTAAGGAGGACAGCAATGATAATGAAGAAGATGAGGGTGGGACATATTTTGTGGACCAGGCAGGAAACTATTACTACCAAGCGACAAAAGATTCAGAACCTGTGCTGACAACACCCCCTGAGGACTATGAAGAGGGCAGCGATGCAGAAGATGACCGATTGAATGACACCGAAGAATTTCTAGAAGACACTGATAATGAAAGCGGCAAAGATAAGAAGGCCAAAGTTTCAGTAGTAAATAATAAGCAGGGAAAGGAGCAAATTAGTTTTGTCCTTATAATGGATGATGAGGCGAAAGGTGATGGTCAGAAAGAAGAAATATATGAGTTCGATGAAAAAGAAGAGGAGGAGGAGAAAGATCAATCCAGCCAAGAAGAAGATAAACCATCTAAGAAAGTTGTGAAGTTGGTACCAAAGAAAGCCACTACGGCAAATGGCCAGATTTTTTATTGCAGCTACTGCAGTTATGCAAGTACGAAGAGGTACTTGCTAGCCAGGCATATGAAGTGCCATTCAGAGGATCGACCCCACAAATGCTCTGTATGTGAGAGAGGCTTCAAAACAATAGCATCATTACAAAACCATATTAATACGCACACGGGTAATAAGCCCCATCACTGCAAGTCGTGCGAAAGTTCGTTTACGACTTCTGGTGAGCTTGTTAGACATGTGAGATATCGGCACACGCACGAAAAACCCCATAAATGCACTGAATGTGATTATGCCAGCGTGGAACTGAGCAAACTGAAGAGACATATCCGTTGCCATACAGGTGAAAGGCCGTATCAGTGTCCGCATTGCACATATGCTTCACCTGATACTTTCAAGCTAAAAAGGCATTTGAGGATACACACTGGAGAGAAGCCGTATGAGTGCGATATTTGTCACGCCCGTTTTACTCAATCTAATTCGCTGAAGGCTCATAAACTCATCCACAGTGTTGGGGAGAAACCTGTGTTCCAATGCGAACTATGTCCCACGACTTGTGGGCGAAAGACAGACTTAAGGATACATGTCCAAAAATTGCATACTTCGGATAAGCCTTTGAGATGTAAACGATGCGGTCAACATTTTCCCGATAGGTATAGCTATAAAGTCCATTCAAAAACGCATGAAGGCGAAAAGTGCTACAAATGTGAATTGTGCCCTTATGCGTCTATATCTGCTCGTCATTTAGAATCCCATATCCTAATTCACACTGACCAGAAACCCTATGAATGCCAACACTGCGACCAAGCGTTTAGGCAGAAACAGCTCCTAAGAAGGCATGTGAATTTGTACCATAATAAGAACTACGTGCCACCGGTACCCAAGGATAAAACACACGTGTGTCCGGACTGCTACAAGGCTTTTAGTCACAAAGGCAATTTAATCCGACACATGGCTCTTCATGATCCAGAGTCTGGGGCGAAAGAGCAACAAGTGGCCTTAAAGATAGGCCGTAAGAAGCGTATTCAAGTCATTGATGGCCAGGCTGTTGAAATTTGCCAAAGTCTGGATGGGGACATGGACGACAGTATGAACGAAGATGGTTATGAGGACTCATGCAATGCGGATATTGCTCCTATTACGAAGGAGGAAAAGGAAATTGTGGCTGTGGAGGGCTCTGACGGGCAACAGTATGTCGTCCTCGAAGTTATCCAAATGGATCCCGAAGCTAGTGGGCCAACGGGTAATACAAATTCAAACATGGAGATTAATGAAGACGGATACATCATGGATTTTCCATCTGAAGTCATAGGTGCTTTAAAAGGGAGCAAAAAGCTGCAGACAAAAACAGAAGAAGGTATCATCGTTGAAGAACAGGAAATGGATAATTGCTTCGGGTTTGAGGAAGATGACAACAGTCAAGTTGATGGAGAAGAACATGAAGACAAAACACAAATTAAATTTGAATTGGAAGATGAAGAGGAATAG
Protein Sequence: MSAKVAEVTEVKVENTNDLQSYLESFNQEIDDGSGTIQILKEDSNDNEEDEGGTYFVDQAGNYYYQATKDSEPVLTTPPEDYEEGSDAEDDRLNDTEEFLEDTDNESGKDKKAKVSVVNNKQGKEQISFVLIMDDEAKGDGQKEEIYEFDEKEEEEEKDQSSQEEDKPSKKVVKLVPKKATTANGQIFYCSYCSYASTKRYLLARHMKCHSEDRPHKCSVCERGFKTIASLQNHINTHTGNKPHHCKSCESSFTTSGELVRHVRYRHTHEKPHKCTECDYASVELSKLKRHIRCHTGERPYQCPHCTYASPDTFKLKRHLRIHTGEKPYECDICHARFTQSNSLKAHKLIHSVGEKPVFQCELCPTTCGRKTDLRIHVQKLHTSDKPLRCKRCGQHFPDRYSYKVHSKTHEGEKCYKCELCPYASISARHLESHILIHTDQKPYECQHCDQAFRQKQLLRRHVNLYHNKNYVPPVPKDKTHVCPDCYKAFSHKGNLIRHMALHDPESGAKEQQVALKIGRKKRIQVIDGQAVEICQSLDGDMDDSMNEDGYEDSCNADIAPITKEEKEIVAVEGSDGQQYVVLEVIQMDPEASGPTGNTNSNMEINEDGYIMDFPSEVIGALKGSKKLQTKTEEGIIVEEQEMDNCFGFEEDDNSQVDGEEHEDKTQIKFELEDEEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00628593;
90% Identity: iTF_01184020;
80% Identity: -