Basic Information

Insect: Neoitamus cyanurus
Gene Symbol: ZBTB46
Assembly: GCA_947538895.1
Location: OX384541.1:31988292-31989770[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0015 0.23 12.8 0.2 3 23 12 32 10 32 0.98

2 15 0.15 22 6.6 0.1 3 13 51 61 50 63 0.88

3 15 0.0036 0.53 11.7 0.2 3 23 94 115 93 115 0.90

4 15 1.2 1.7e+02 3.8 7.8 1 23 121 143 121 143 0.95

5 15 0.0001 0.015 16.6 0.6 1 23 149 171 149 171 0.97

6 15 4.5e-06 0.00067 20.8 0.1 1 23 179 201 179 201 0.97

7 15 0.0002 0.03 15.6 1.9 1 23 208 230 208 230 0.97

8 15 0.0003 0.044 15.1 0.7 1 23 236 258 236 258 0.98

9 15 6.3e-05 0.0093 17.2 0.2 3 23 268 288 266 288 0.96

10 15 0.0061 0.9 11.0 0.4 1 23 295 317 295 317 0.97

11 15 1.4e-06 0.00021 22.4 3.3 1 23 323 345 323 345 0.98

12 15 6.3e-06 0.00093 20.4 1.1 2 23 354 375 353 375 0.98

13 15 5.7e-08 8.5e-06 26.8 1.5 1 23 383 405 383 405 0.98

14 15 0.0013 0.2 13.0 2.6 1 20 411 430 411 431 0.96

15 15 0.73 1.1e+02 4.4 5.3 1 23 440 462 440 462 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0015	0.23	12.8	0.2	3	23	12	32	10	32	0.98
2	15	0.15	22	6.6	0.1	3	13	51	61	50	63	0.88
3	15	0.0036	0.53	11.7	0.2	3	23	94	115	93	115	0.90
4	15	1.2	1.7e+02	3.8	7.8	1	23	121	143	121	143	0.95
5	15	0.0001	0.015	16.6	0.6	1	23	149	171	149	171	0.97
6	15	4.5e-06	0.00067	20.8	0.1	1	23	179	201	179	201	0.97
7	15	0.0002	0.03	15.6	1.9	1	23	208	230	208	230	0.97
8	15	0.0003	0.044	15.1	0.7	1	23	236	258	236	258	0.98
9	15	6.3e-05	0.0093	17.2	0.2	3	23	268	288	266	288	0.96
10	15	0.0061	0.9	11.0	0.4	1	23	295	317	295	317	0.97
11	15	1.4e-06	0.00021	22.4	3.3	1	23	323	345	323	345	0.98
12	15	6.3e-06	0.00093	20.4	1.1	2	23	354	375	353	375	0.98
13	15	5.7e-08	8.5e-06	26.8	1.5	1	23	383	405	383	405	0.98
14	15	0.0013	0.2	13.0	2.6	1	20	411	430	411	431	0.96
15	15	0.73	1.1e+02	4.4	5.3	1	23	440	462	440	462	0.90

Sequence Information

Coding Sequence: ATGTTTGAAGAAGATTGGCCGAATTCTTTCGGTTGCGATGATTGCGGAATACAATTCGGGGACATCAAGAGCTTTATGACACACCGAAGAATTCATTTTGCAACAGATCCTGATATTCAACCGAAAGGAAAAAACATTCAAGAAGGAATTTGCCCCCACTGCAATTTGTCATTTTACGATAAAACTTTGAGTCCGGAAGAAGTCGACCGATTAAGAAAATCTAAGAAGCGTTCAGAACTTGGTAAGAAAAAGAGATTTAAAGTAAGGGAATGCAGATATTGCTTGATATGCAAGATATCTTTCCGAAATGCAAATGAGTTGCTCATTCATTCAAAGGACGTCCATGGTGTTGAACGGCCGTACAAATGTAAGAAATGTGACTTTACTACTTCTATTTACCATCATATAAAAAGGCACTCCTATTCCCATAATGATACAAAGCTTTACCCCTGCCATCTCTGCCCAAAGGAGTATACAACAAAAACGTCATTAGATGGGCATTTGCTGATACATGCGGAAGTTGATATAAAGTCATACGACTGTGAATTGTGTGGGAAAAAATTTCCAATTCCTTCTCTACTCAAAAGACATTTGGGGACGCACGTCCCCGGCCAGAAGATTTTCAAATGTGAATTGTGTCCCAAGGAGTTTATGTCGAAGAAGGGCTTAAAATTACACACCTTTAAGCATACTGGGGAGAAGCCCTTCCAATGTCGGATATGCCAGAGGGGGTTCATAGAACCTTTTAAATACAGACTTCATATGCAGGTACACAATCAGATTATAGGTAACGTGATCGACTGTGAATTTTGTGGCAAACAGTTCCTCACACCATATTTGCTAAAAAAACATATGATAGTGCACGATAATAGTGGAGCTCAGTTCATATGCGACGTGTGCTCGAAACCATTTCTTCGTGAGGTAACCCTGAATTTGCACAAAAAAAGTCATACTGGTGATCTTCCATACCAATGTGACGACTGCGGTAAGAAGTTCACTAATAGACACAAATATGCGAGGCACAGGATAATTCATATAAACGCCAATGAGGATCCCGTGAAATGTGATCATTGTGGTAAGGAATTCTCTGCCATGTACAAACTGGAAAGGCACATTAAAATACACACTCGTGAGGAGAATGACATGTATAAGTGCGAGATTTGTTCCAAGTCATTTACCAGAAAACAAAACCTAAAAGATCATCTTTTAATACATGAAGGAAAGCAGCCGTACAGCTGCAAGCATTGCGGAAAGAAATTCCTTAAGCAAAAGTATCTCAAAATACATCTTGATCCTGACAAGAACTTTGGGAAACTCTTTAGATGTAAGAAGTGCTCTATAACTTTCACTATTAAAAGTTGTTTCGTATTTCACGCTAAGAGTCATAAGAAAAGTCCTTCGACTACAAAAGATCATATAAATCAGCATATGAAGCACGAAGCGGCAGAGCGCGATGTTGAAATCAAAGAGGAAGTGTGA
Protein Sequence: MFEEDWPNSFGCDDCGIQFGDIKSFMTHRRIHFATDPDIQPKGKNIQEGICPHCNLSFYDKTLSPEEVDRLRKSKKRSELGKKKRFKVRECRYCLICKISFRNANELLIHSKDVHGVERPYKCKKCDFTTSIYHHIKRHSYSHNDTKLYPCHLCPKEYTTKTSLDGHLLIHAEVDIKSYDCELCGKKFPIPSLLKRHLGTHVPGQKIFKCELCPKEFMSKKGLKLHTFKHTGEKPFQCRICQRGFIEPFKYRLHMQVHNQIIGNVIDCEFCGKQFLTPYLLKKHMIVHDNSGAQFICDVCSKPFLREVTLNLHKKSHTGDLPYQCDDCGKKFTNRHKYARHRIIHINANEDPVKCDHCGKEFSAMYKLERHIKIHTREENDMYKCEICSKSFTRKQNLKDHLLIHEGKQPYSCKHCGKKFLKQKYLKIHLDPDKNFGKLFRCKKCSITFTIKSCFVFHAKSHKKSPSTTKDHINQHMKHEAAERDVEIKEEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01049844;
90% Identity: -
80% Identity: -