Basic Information

Insect: Neoitamus cyanurus
Gene Symbol: ZEB2_2
Assembly: GCA_947538895.1
Location: OX384541.1:31976219-31977724[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00011 0.017 16.4 1.4 2 23 12 33 11 33 0.97

2 15 0.00053 0.078 14.3 0.5 2 23 92 114 91 114 0.95

3 15 0.0031 0.46 11.9 1.4 1 23 120 142 120 142 0.96

4 15 0.00014 0.021 16.1 1.9 1 23 148 170 148 170 0.98

5 15 3.7e-06 0.00055 21.1 1.6 1 23 178 200 178 200 0.96

6 15 4.9e-06 0.00072 20.7 1.4 1 23 207 229 207 229 0.98

7 15 4e-07 5.9e-05 24.1 4.2 1 23 235 257 235 257 0.98

8 15 6.1e-06 0.0009 20.4 2.5 2 23 266 287 265 287 0.98

9 15 1.2e-05 0.0018 19.5 0.6 1 23 294 316 294 316 0.97

10 15 3.3e-06 0.00048 21.2 2.2 1 23 322 344 322 344 0.96

11 15 2.2e-05 0.0033 18.6 0.8 3 23 352 372 351 372 0.98

12 15 8.9e-06 0.0013 19.9 2.6 1 23 380 402 380 402 0.98

13 15 3.4e-05 0.005 18.1 0.6 1 20 408 427 408 428 0.95

14 15 0.00077 0.11 13.8 8.0 2 23 438 459 437 459 0.97

15 15 0.71 1.1e+02 4.4 4.4 1 23 463 485 463 485 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00011	0.017	16.4	1.4	2	23	12	33	11	33	0.97
2	15	0.00053	0.078	14.3	0.5	2	23	92	114	91	114	0.95
3	15	0.0031	0.46	11.9	1.4	1	23	120	142	120	142	0.96
4	15	0.00014	0.021	16.1	1.9	1	23	148	170	148	170	0.98
5	15	3.7e-06	0.00055	21.1	1.6	1	23	178	200	178	200	0.96
6	15	4.9e-06	0.00072	20.7	1.4	1	23	207	229	207	229	0.98
7	15	4e-07	5.9e-05	24.1	4.2	1	23	235	257	235	257	0.98
8	15	6.1e-06	0.0009	20.4	2.5	2	23	266	287	265	287	0.98
9	15	1.2e-05	0.0018	19.5	0.6	1	23	294	316	294	316	0.97
10	15	3.3e-06	0.00048	21.2	2.2	1	23	322	344	322	344	0.96
11	15	2.2e-05	0.0033	18.6	0.8	3	23	352	372	351	372	0.98
12	15	8.9e-06	0.0013	19.9	2.6	1	23	380	402	380	402	0.98
13	15	3.4e-05	0.005	18.1	0.6	1	20	408	427	408	428	0.95
14	15	0.00077	0.11	13.8	8.0	2	23	438	459	437	459	0.97
15	15	0.71	1.1e+02	4.4	4.4	1	23	463	485	463	485	0.97

Sequence Information

Coding Sequence: ATGACCACTTTGGAGAAATTACTGGGCGATATCAGCTGTGATGACTGCGGTTTTAATTTTAAGAGCTACTCAGAATATTTTCTGCACAGAAAGAGACATACCTTGCTACTGCGGCGAAAGATCACGGAGAAAACGCTGCTAGAAGGATGCTGTCCGATGTGTTTCTTGAAATATTGCAAGAAGTACAAAGACGTATGTTTAGAAGATCTGCTGGGGAGCGGGAAAATAATTAAAAAAGAGCTGGATGACTCGAAGAAGGTAATGGGCTGCAAGTATTGCCCGAAATGTGATATTCAGTTCCGCACTTCGAACATGTTTCTCAACCATGCGAAGGTAGTCCATAACGATGAAAGGCCGTATGCCTGCACAAAGTGTAATTTTGCATCTTTCCGATACCAAGATCTCAAGCGCCACATTTACATTCATGTGGACTACAAAATGTTCAGGTGTCATCTCTGCCCAAAGGAGTATACAACCAAAACCTCATTAGACGGTCATTTGCTGAGCCACAACGGCGTTAACATAAAGTCTCATGACTGCCCTTACTGTGGTAAGAAGTTTCCCATTCCCCATTTGCTGAAGCGCCACGTTAAAGTGCATAATCCTACCTCAGAAACGTTTAAGTGTAGTATGTGCCCTAAGGAATTCGCCTATAAGCAGAGCTTAAAACTTCACATGCTTTACCACACCGGTGAAAAACCGTACGAGTGTCCATACTGCCAGAAACGGTTCACTCAGCGCTTCAACTATCGCCGGCACTTACAGAGGCACAATCATATCCTCGGAACACTTATAAAATGTACTTATTGTGACAAGCAGTTCCTCACCAGATACCTTTTAAAAAGGCACATGCAGACCCACGAGAAGGACGAGAACGCTTTTATTTGTGATATATGTTCCAAGCCCTTCACACGGGAGCAGAGCCTCAACTTGCACAAGCTGACCCATACGGGTAACATGCCATTCACCTGCGAGTATTGTGATAAGAAATTCACCCGCATCTCCAGCTACAATCGGCATCGGGTCATTCACGTTGATGCCGATCGAGTCGATTGTGAGCATTGTGGGAAAAGCTTTCCAGGACTGTATCGGCTGCAGAGGCACGTAAAAATACATACCAGGCCAACTGAGAAGCCGTTTAAATGCTCACTATGCCCGAAACGGTTCTCCAAGAAGCCAGATTTTAAAAATCACCTACTGAAACACGAGGGTCGGGAGCCATATGATTGCCAGCACTGTGGGAAGAGATTTATTAAACAGCGAGCACTTAAGATTCACCTCGATCCGGACAAGCAGGCGATACATACTCTGAGGTGCCGCGAATGTCCGAAGACGTTTAAACATAAGAATTGTTTAACGTACCACAAACGGTCTCACAAAGATGAATATTTCTGCGATACCTGCAAGGGAAAATTCTTAACTCATGATGGTTTCCGGAACCACTTAAAAAGACATGCCGTAAATAAGAATGCAAACATTAAGATGGAATTTAAACAAGAGATGTAG
Protein Sequence: MTTLEKLLGDISCDDCGFNFKSYSEYFLHRKRHTLLLRRKITEKTLLEGCCPMCFLKYCKKYKDVCLEDLLGSGKIIKKELDDSKKVMGCKYCPKCDIQFRTSNMFLNHAKVVHNDERPYACTKCNFASFRYQDLKRHIYIHVDYKMFRCHLCPKEYTTKTSLDGHLLSHNGVNIKSHDCPYCGKKFPIPHLLKRHVKVHNPTSETFKCSMCPKEFAYKQSLKLHMLYHTGEKPYECPYCQKRFTQRFNYRRHLQRHNHILGTLIKCTYCDKQFLTRYLLKRHMQTHEKDENAFICDICSKPFTREQSLNLHKLTHTGNMPFTCEYCDKKFTRISSYNRHRVIHVDADRVDCEHCGKSFPGLYRLQRHVKIHTRPTEKPFKCSLCPKRFSKKPDFKNHLLKHEGREPYDCQHCGKRFIKQRALKIHLDPDKQAIHTLRCRECPKTFKHKNCLTYHKRSHKDEYFCDTCKGKFLTHDGFRNHLKRHAVNKNANIKMEFKQEM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00937477;
90% Identity: -
80% Identity: -