Basic Information

Insect: Neodiprion pinetum
Gene Symbol: ZBTB2
Assembly: GCA_021155775.2
Location: CM037741.1:29564846-29570325[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.18 27 6.3 1.7 1 23 303 325 303 325 0.90

2 12 0.00014 0.021 16.1 1.3 1 23 330 354 330 354 0.94

3 12 0.0051 0.77 11.2 0.2 2 23 413 435 412 435 0.95

4 12 1.3e-05 0.0019 19.4 1.9 1 23 441 463 441 463 0.97

5 12 0.004 0.6 11.6 0.1 1 23 472 495 472 495 0.89

6 12 2.3e-07 3.5e-05 24.9 3.6 1 23 501 523 501 523 0.98

7 12 1.8e-06 0.00027 22.1 0.4 1 23 529 551 529 551 0.98

8 12 0.00012 0.017 16.4 2.3 1 23 557 579 557 579 0.97

9 12 1.7e-08 2.6e-06 28.4 0.5 1 23 585 607 585 607 0.99

10 12 1.1e-05 0.0017 19.6 5.7 1 23 613 635 613 635 0.98

11 12 1.1e-05 0.0017 19.6 1.6 1 23 669 691 669 691 0.98

12 12 1.2e-07 1.9e-05 25.7 1.9 1 23 697 719 697 719 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.18	27	6.3	1.7	1	23	303	325	303	325	0.90
2	12	0.00014	0.021	16.1	1.3	1	23	330	354	330	354	0.94
3	12	0.0051	0.77	11.2	0.2	2	23	413	435	412	435	0.95
4	12	1.3e-05	0.0019	19.4	1.9	1	23	441	463	441	463	0.97
5	12	0.004	0.6	11.6	0.1	1	23	472	495	472	495	0.89
6	12	2.3e-07	3.5e-05	24.9	3.6	1	23	501	523	501	523	0.98
7	12	1.8e-06	0.00027	22.1	0.4	1	23	529	551	529	551	0.98
8	12	0.00012	0.017	16.4	2.3	1	23	557	579	557	579	0.97
9	12	1.7e-08	2.6e-06	28.4	0.5	1	23	585	607	585	607	0.99
10	12	1.1e-05	0.0017	19.6	5.7	1	23	613	635	613	635	0.98
11	12	1.1e-05	0.0017	19.6	1.6	1	23	669	691	669	691	0.98
12	12	1.2e-07	1.9e-05	25.7	1.9	1	23	697	719	697	719	0.98

Sequence Information

Coding Sequence: ATGGAGGTCCCGCTTTATGATTCAGCGGTTTGTCGATTATGTGCCGAAGACAATGGCAACGGAGAATTCTTGTACGCAGCCGACGGCGAAGAGTCGGATTTAAGCTCCATGGTGAACCGCTACTTGCCACTGAAGATACGAGATGACGGTAAACTACCTCGCACTATCTGCCCAGGATGCAACATCCAGCTGGAGGCAACTGTACAGTTCTTCGAATTACTCGTCGAAGGGCAAAAGAAAATTCGTGAGATGTGGAAATCACAAGTCGAACAACATCGCAAGGCTGAGAGGGAGCGCCTTCGTGCTGAAAGGGAACACACTGAGTTGGAAATTGTCACTCCTGAACTTGATCATTTTGGATTACAAGCTGAGGGCGATCACATTGAACGGCAAATTGTTATTAAAATCATGCCAGATGGAACTCTGTATACGGCGGAACATGAGATGAGTTTACAAATGGAAGGGTTGGATAAGCCTAGAAGAAAACGAGGCCGACCCCCGAAGGCCCATACTGAGGCTGAGACTAAGGAGAATGTAAAGGAATTGAAACAAGAAGTCGGCAGTCAAGGGGAAGAAGATAAGCAAGAGGAGGAACTTGAGGAAGTAGATGGTGATGGTAGACGTCGCCGAAAACGAAAAGTGCCCAAAAGATTCATGGAAGCTGTGCAGGGAAAGGAACTAGAGAGGATATTTAAAGAAGAAGGAGTAATCGATGAAGAAGATGATGATGAGCCTGGAGATGACTTTGATGATCCGGAAGAACGACTGAATTTGCCAACAACGGACGGTCATGAAGAAATTATCGGGCATCTGGAGACTCAAGAGGGGAAAGATCTTGGTGAACTAGTGATAGTAAATCGTGGAAGAGGCAGAGGCAGGCCACGGCTTCGGCGACGTAAGACCAAATTCACATGTAATTTGTGTGGACGAGGATTTCTGCAGCGTAGCAGATATATTATGCACAAGAGCTTTCACAAAGGCGTCAAGTACGAATGCCTCGAGTGTAAGAAGCAGTTTACGAATAGAGACAATTTTGGTCTTCATCAGAAAACTACAGGACACACTGGCGAAGGAATAATAGAAAATCCAGAGGAAAACGAGGTTCGCAATCAAGAGCCTCCAACAACTGAGGGAACGGAAAATGCAGCAGCTGCGTCACCCAAAGAGACGCAAGATGTACCTGGAGAAGCTTCTGTGGCAGAAGAAAAACCGCGTGAAGTTGGTGGAAAAATGATAGAGTGTGAACTCTGCCAAAAACAATTCCAGTCAAAGCAGAGCTATGAGGTTCATGCAAAGGTTGTTCACCAAGGGGAAAAACCTTATACGTGCAACATATGTAACAAGACCTTTGCCTATCACACAAGCCTAAAAGGGCACATGCTTGCACATGAGGCTAATAAATCTGACAAGGGATTTCCTTGTGACATATGTGGAAAGGTTCTAAATCATCCTAGCTCAGTTGTGTACCACAAGGAGGCTGAGCACAATAATGGCCGTCGTTTCGTATGCAATAAGTGTGGAAAAAGCTTCAAGCACAAACAGCTGTTGCAGCGTCACCAGCTGGTACACTCGGATGATCGCCCATATGTTTGCAAGTCTTGTGGTGCTACTTTCAAGACTAAAGCCAATCTGATAAATCACCAATCCATCCACACTGGAGAGAAAAAGTATTTCTGCGAATTATGTGGACAGCAATTTGCACACAAGACCAGTCTCACCCTGCATTATAGATGGCATACAGGTCACAAACCTTACACATGTGAAGTGTGTagtaaaagtttttcacagAACGGCAATCTGCAGGAACATATGAGAATTCACACAGGAGAAAAGCCTTACTGTTGTGATTACTGCGGTCGAAAGTTTACCACCTCCTCGCAGTTCAAACTTCACGTCAAACGACATACGGGCGAGCGTCCCTGGAAATGTGAATTTTGCGCAAAATGCTTCCTGCACAAGGATACGTGGAAGTGTCACGTCAGACGGCATAAGGGTGAACGCCCCTTCCAATGTGCCCACTGCAATCGGGGGTTTACTGAGCAGTGGGCTCTCAAAAAACATCTACGATTACACACAGGGGAAAAGCCATACTCATGTAATATCTGTGGTAAAGCTTTCGCTGATTGCTCGAACCTCACTAAACACAAAAAGgtgcacAGAGAAAATAAAGTGGTTGATGTCGGGGAGCTTGCAGAAAATTCTCCCATCGGCGAGGTATGGCAGATATTACCTGGTGCACAACAGGGCGACGAGAATTCACTTGGAGATCAAGTGACTCAAGTTATTGGAACTGATGAGGCATCGGGTGATGGCATACAGCAAATTATATATGTGTCGTATCAAGATCCAGACGATCCGAATCAGTCGAGAACATTACACTTTGTTGATGCTGGAATGATGGAGAATAAGGAGGTAGCTGCAGTAGCAGGGAGCCAATCATTGCCGTCTTTGGACGTCGAAGATGAAGATGAGACAACCCAACAGCCTGTACAAGATGAAGAGAATCTCGAGCCAGATGAGAGAATTAACATGGAATTAGCCGAGTCTGACTTACAACTGCAGATTACCGATGAGGAAGGAAATCCTATTCCACTTTCAATACAAGATGCACGACAATTACTGTCAGAAGGTCAGTTTGTCAGTCAATTGGGTGACTGTCAGACAATTAGAGTTCACTCAGGAGTCTTAACTCAAGAATTGGCGCAACAACTAGAAGTTGAAGATCAAGGTTCCATGCCGATCGAGGATCCAAACGAAACCGTAACAGAGGATCCAAGTAGCACCGTAGCCTTGACTTCGACAACTCACACTGACGCTGAAGACATTGTCAAGGCGTTGGAGGATGAGGATACTGATGCGACAGCTGTTGCTGCCGTTAATCAGATGGAAACCGAGGAACAGACTGAAGACATAATGGATGGTGAGCAAACGATAGAATTCACAACTCAAGATGGTCAGAAAGTGCGACTTGTAACGTCCTACCACGTCGACCCAATGCAACTTGCCTCCGAATACTTGACTATTGTGTAG
Protein Sequence: MEVPLYDSAVCRLCAEDNGNGEFLYAADGEESDLSSMVNRYLPLKIRDDGKLPRTICPGCNIQLEATVQFFELLVEGQKKIREMWKSQVEQHRKAERERLRAEREHTELEIVTPELDHFGLQAEGDHIERQIVIKIMPDGTLYTAEHEMSLQMEGLDKPRRKRGRPPKAHTEAETKENVKELKQEVGSQGEEDKQEEELEEVDGDGRRRRKRKVPKRFMEAVQGKELERIFKEEGVIDEEDDDEPGDDFDDPEERLNLPTTDGHEEIIGHLETQEGKDLGELVIVNRGRGRGRPRLRRRKTKFTCNLCGRGFLQRSRYIMHKSFHKGVKYECLECKKQFTNRDNFGLHQKTTGHTGEGIIENPEENEVRNQEPPTTEGTENAAAASPKETQDVPGEASVAEEKPREVGGKMIECELCQKQFQSKQSYEVHAKVVHQGEKPYTCNICNKTFAYHTSLKGHMLAHEANKSDKGFPCDICGKVLNHPSSVVYHKEAEHNNGRRFVCNKCGKSFKHKQLLQRHQLVHSDDRPYVCKSCGATFKTKANLINHQSIHTGEKKYFCELCGQQFAHKTSLTLHYRWHTGHKPYTCEVCSKSFSQNGNLQEHMRIHTGEKPYCCDYCGRKFTTSSQFKLHVKRHTGERPWKCEFCAKCFLHKDTWKCHVRRHKGERPFQCAHCNRGFTEQWALKKHLRLHTGEKPYSCNICGKAFADCSNLTKHKKVHRENKVVDVGELAENSPIGEVWQILPGAQQGDENSLGDQVTQVIGTDEASGDGIQQIIYVSYQDPDDPNQSRTLHFVDAGMMENKEVAAVAGSQSLPSLDVEDEDETTQQPVQDEENLEPDERINMELAESDLQLQITDEEGNPIPLSIQDARQLLSEGQFVSQLGDCQTIRVHSGVLTQELAQQLEVEDQGSMPIEDPNETVTEDPSSTVALTSTTHTDAEDIVKALEDEDTDATAVAAVNQMETEEQTEDIMDGEQTIEFTTQDGQKVRLVTSYHVDPMQLASEYLTIV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01303649;
90% Identity: iTF_01048378;
80% Identity: -