Basic Information

Insect: Neoascia interrupta
Gene Symbol: L
Assembly: GCA_947623515.1
Location: OX392462.1:155616176-155626399[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 4.9e-06 0.00071 20.8 1.7 1 23 190 212 190 212 0.98

2 15 0.41 60 5.4 5.8 1 23 218 240 218 240 0.98

3 15 2.1e-07 3.1e-05 25.1 3.1 1 23 246 268 246 268 0.99

4 15 9.8e-06 0.0014 19.9 0.3 1 23 274 296 274 296 0.98

5 15 7.5 1.1e+03 1.4 0.2 2 23 359 382 358 382 0.81

6 15 0.0036 0.53 11.8 0.4 2 23 396 418 395 418 0.97

7 15 0.018 2.6 9.6 1.4 1 23 499 521 499 521 0.97

8 15 0.00041 0.06 14.8 1.1 2 23 529 550 528 550 0.94

9 15 0.0004 0.059 14.8 1.3 1 23 558 583 558 583 0.90

10 15 0.0013 0.19 13.2 2.9 1 23 675 697 675 698 0.96

11 15 0.00093 0.14 13.7 4.6 2 23 876 898 875 898 0.96

12 15 0.11 16 7.2 0.1 1 23 904 926 904 926 0.92

13 15 0.047 6.9 8.3 0.3 2 23 934 955 933 955 0.96

14 15 0.045 6.5 8.4 0.0 1 23 1075 1097 1075 1097 0.96

15 15 0.23 34 6.1 1.1 1 23 1104 1126 1104 1126 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	4.9e-06	0.00071	20.8	1.7	1	23	190	212	190	212	0.98
2	15	0.41	60	5.4	5.8	1	23	218	240	218	240	0.98
3	15	2.1e-07	3.1e-05	25.1	3.1	1	23	246	268	246	268	0.99
4	15	9.8e-06	0.0014	19.9	0.3	1	23	274	296	274	296	0.98
5	15	7.5	1.1e+03	1.4	0.2	2	23	359	382	358	382	0.81
6	15	0.0036	0.53	11.8	0.4	2	23	396	418	395	418	0.97
7	15	0.018	2.6	9.6	1.4	1	23	499	521	499	521	0.97
8	15	0.00041	0.06	14.8	1.1	2	23	529	550	528	550	0.94
9	15	0.0004	0.059	14.8	1.3	1	23	558	583	558	583	0.90
10	15	0.0013	0.19	13.2	2.9	1	23	675	697	675	698	0.96
11	15	0.00093	0.14	13.7	4.6	2	23	876	898	875	898	0.96
12	15	0.11	16	7.2	0.1	1	23	904	926	904	926	0.92
13	15	0.047	6.9	8.3	0.3	2	23	934	955	933	955	0.96
14	15	0.045	6.5	8.4	0.0	1	23	1075	1097	1075	1097	0.96
15	15	0.23	34	6.1	1.1	1	23	1104	1126	1104	1126	0.93

Sequence Information

Coding Sequence: ATGTCATTTAAATTAATCGAACGACTTGGCTTCATTTCAGATCTGTACTCTACGCACACCTCGTCCAGCTACTCGCCCTCGATGTCGGACGGGACAATTACGCCGAACTCGCTGCACAACCACCACCATCATCATCACCAGCAGCGACTGCACCACTTGCAGTACCAGTGTGAACAGCCAAACAGCGGTGGTCATCACAATCGCGACAGGCATTACAATCGACGTGTCTCGACCATAAATGGAGCAACTGCCAGCGGTGTTCTCGGCGAGGACGACGACAACGAAGACGATGACGGCGAAGTGGTGGACGAAGATGAAGACGCCGCAAATTCTGGCGAGGAAAAGGTTTTCCTCTCCTCAAACGGTGGTGGGGCCAACAACGATGCCAACACCACAACCACCACCACCACATCATCATCCACCACCGCGAGCAGCATCAGTGGCGCAACCGGCGAGCATTCCGTGAAAATTCCAACGAAATTGCGGAAAATCGATAGGGATTCGGCAAAGTTGCTGGATAAGTTGACAAGTGATGGCATTAAGAGCGCGACCGACCGCGACGGATCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGCCTTGGGTATCTGAAGAAGCATGAACAGAGTCATGCTGAGCACCTTCCGTTTAAGTGTGACTATTGTGCCAGGCTGTTTAAGCACAAGAGGTCGCGTGATCGACACACTAAACTGCACACTGGAGACAGACGATACAGGTGTCCGCACTGCGAAGCTGCATTTTCACGCAGTGATCACTTGAAGATCCACATGAAGACGCACGACAACCAGAAACCATTCCAATGCACCATCTGTAACCGCGGCTATAATACAGCGGCGGCTCTGACCTCGCACATGCAAAACCACAAGAAGCAAGCAGCACTTTTGGCTGCTGGCGGTAACCCTGCTGCTCTTAACTACAGCCCTCGCTCAACTGGATCTGGTTCGAGTAACGGAAGCTTACAGAAGCGTCGATACGCCTCAGTAGCAATGAACAAAAGCCCCAGTCCAGGTAGTCTGGACTACGCCAAACGCTTGCGCAACTCCTACATCTCCTGCATGTATTGTACGAAATCAGACTTCGCATCAATGGAGCAACTGAGCTCTCACATACAGGCCATGCATGAAAAGGAAGCCTTGGCCAATCAAACCAACTTCCAGATGTCCTGTGAGTACTGCACTATGAAATTTCCCAGCATCCCAGCAATGTTCCAGCACATGAGAACGACCCATATCGATCGGCTGTCCAGCCCGAGCAGCTACTTTGAACACTTCAATCGGTTAGCAGCGTCGGGAACATTCAGTCCACGATTGCCAACACCCAAGTCAAACGAAGTGAAAGTCAAAGTCGAAGAGCCAAGTCCGAGGGAGATTGAGAAGCCCGACGACGAACCGACAGATTTGAGTCAGAACAAACGCACCGCACAGACGCCTTCGCACGAGTCTGCTGAAGCAGTCGAGAAACCAGGTGTGTTCTTCTGCAATCAGTGTAACGATGGTTTTCCAGATTTCGACAGTTTCCGCAATCACCTCAAATCGCATATAGTTCAGGGACTTAATCTGATTTGCCACCACTGTGGTCAAGCACTGCGCGATCAGAGCGAGTACGAAAGACATGTTGTGTCACATTTTCTCATAACCAGCTCGGAGTATAACTGCACCGAAAAAAATTGCAGCAAGTCGTTTACGAAGCCAGAGGATCTGCAAAAACACCTCTTTGACAGTCACATACAGTCGTTGTACAAATGTCTCTTGTGCTCGGACTTATTTGAGACAAAGGTTGCCATCCAGGTGCACTTTGCATGCATTCACTCGCCAGAGAATAAGATTCTTCGCTGCTCGGCCTGCATGGACACTTTTCATAGCGAGCAAGAGTTTCATATCCATGTTAAGACCAGACATCAAACTGCAGCAGGCTCACCTATCCAGTGTATGTTTTGCAGAGCAGTTTGCTCCACCGAGCTGGAGATGCACTTCCACCTGGCTGCCCATGCTCGACAATTTCGCTGCCCGTCGTGTCCAGAGACGTTTCACGTTGAATTTTTGCTTGACCGTCACATGCAGACGCACCACGGACAAAAAGACGTGGATGCGCCACCGACGGTCAATCCAGCATCAATCAATCCACTTTACATGAGTGCTCTATTCAACAAGCCACCTCCGTCGAGCCAAAACAACAACAACAGCATTCTTGACTACAACGCATTCGCTATGGGCAAAAATATTTTCGCCAACGCCTCGGGGAACAAGTTTTACAACCCCCTACAAGTGGATACTGCAACCACCATGAAACACCCCTCGCTGGTGTATGCCAGCCTTAATCAGCGCTACTTCGACACCAATCGAACCATCCTCGAGATGTACAGCCAGCATCAGCAGGAAAAACTAAGCGGTAATGCAGTGGCAAACTACTTCAGCAGCCCAAGCAACACACCAAGCAGAAGCGCACAGAAGCCTCAGCAGGAGAGCAGTAAGCCATCTTTGGACCGTCCAATTGCCGGCGGCTTTAGCTGCGGCATGTGCGAACGCAACGACTTCCGAACTGAAGCCGAGATCCACTCACATCGAAAGATCGTTCACAACCTCAAGACGGGCGTAAGTCTGCGCTGTGCCTACTGCAGCGGCAACTTTAAGTCGCGAAGCGAGCTGGAACATCACATGAAGACTTGCCACAACTCCACCGGCAAGCACAAATGTCTCATATGCGATGAGATTTTCCCATCACCAGCCATCCTCGCCGAGCACAAGCTCCAGCACTCCAAAGTTGGCCAGTCTGGCAAATGTTCACACTGCGCAAAGGCCTTGGCAGATGTGTCTGCATTCAAGAGTCATCTATTGGAGCACAACACTGAAGGACAAATGCCGGTGCAATGCATTTGCTGCCGTCAGACACTTCATTCTGACTTTGAGATCGGCCTACATGCCAAATTTCACACAAAGTCCTCCTCGGTTACCGAGAGCGTGTGCGCCTTATGCTTGGAGACAATCCCCAACACAACCGACGCCAAGGTGTGCGACAAATGCTGTCGCAAGCACAACCTCAGCAACAAGTTCAACAATCAGCGCAGCTTTGACACCAGCTCTGGACCACCGAACTATGTGGAGAACCGATGCAACTTGTGCAAGGTCATAATGCCGCATGCACAGAAACTGCAAGAGCACCTCGTCGAGCACACCTTCGCCGGCTGCGAAGACAGAGGCTTCACTTGCTACATTTGCTCCGCGGTTTTTACGGCGCCAGTAGGTCTGCTCGGTCACATGACTGAGCACGGAGCAAACTCACGTCCATACGACTGTAACCTTTGCAGCGAAAAGTATTATTTCCGCGCCGAGCTCGACCATCACCTCGTCGACCACGAGATGAGGGATCGTAACAAGAGTGCCGAGCCAGCAATTGCCGACGGGAAAAAGGCCTTCGACGAACTTCCTCCAGCAGAAGAGCGAGCTCCGAAGCCCGAAGTGAAGAACGAAACCGCCGAGGAGAAACCAGCCGACGACGACGACGACGAGTACATCGAAGTTGAGAAGGTACCCGAAGTTGTACAAGATAAATCATGTTCCTCCGACAAGGAAGACTAG
Protein Sequence: MSFKLIERLGFISDLYSTHTSSSYSPSMSDGTITPNSLHNHHHHHHQQRLHHLQYQCEQPNSGGHHNRDRHYNRRVSTINGATASGVLGEDDDNEDDDGEVVDEDEDAANSGEEKVFLSSNGGGANNDANTTTTTTTSSSTTASSISGATGEHSVKIPTKLRKIDRDSAKLLDKLTSDGIKSATDRDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAALLAAGGNPAALNYSPRSTGSGSSNGSLQKRRYASVAMNKSPSPGSLDYAKRLRNSYISCMYCTKSDFASMEQLSSHIQAMHEKEALANQTNFQMSCEYCTMKFPSIPAMFQHMRTTHIDRLSSPSSYFEHFNRLAASGTFSPRLPTPKSNEVKVKVEEPSPREIEKPDDEPTDLSQNKRTAQTPSHESAEAVEKPGVFFCNQCNDGFPDFDSFRNHLKSHIVQGLNLICHHCGQALRDQSEYERHVVSHFLITSSEYNCTEKNCSKSFTKPEDLQKHLFDSHIQSLYKCLLCSDLFETKVAIQVHFACIHSPENKILRCSACMDTFHSEQEFHIHVKTRHQTAAGSPIQCMFCRAVCSTELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHGQKDVDAPPTVNPASINPLYMSALFNKPPPSSQNNNNSILDYNAFAMGKNIFANASGNKFYNPLQVDTATTMKHPSLVYASLNQRYFDTNRTILEMYSQHQQEKLSGNAVANYFSSPSNTPSRSAQKPQQESSKPSLDRPIAGGFSCGMCERNDFRTEAEIHSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCAKALADVSAFKSHLLEHNTEGQMPVQCICCRQTLHSDFEIGLHAKFHTKSSSVTESVCALCLETIPNTTDAKVCDKCCRKHNLSNKFNNQRSFDTSSGPPNYVENRCNLCKVIMPHAQKLQEHLVEHTFAGCEDRGFTCYICSAVFTAPVGLLGHMTEHGANSRPYDCNLCSEKYYFRAELDHHLVDHEMRDRNKSAEPAIADGKKAFDELPPAEERAPKPEVKNETAEEKPADDDDDEYIEVEKVPEVVQDKSCSSDKED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01542500;
90% Identity: -
80% Identity: -