Basic Information

Insect: Neoascia interrupta
Gene Symbol: ZFX
Assembly: GCA_947623515.1
Location: OX392463.1:124033658-124042159[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00029 0.042 15.3 1.7 1 20 683 702 683 705 0.93

2 7 0.00013 0.018 16.4 0.2 2 23 712 734 711 734 0.96

3 7 0.00034 0.049 15.1 3.3 1 23 740 762 740 762 0.99

4 7 0.00015 0.022 16.2 0.8 1 23 768 790 768 790 0.96

5 7 7.4e-05 0.011 17.1 4.3 1 23 796 818 796 818 0.98

6 7 3e-06 0.00043 21.5 2.6 1 23 824 846 824 846 0.97

7 7 1.8e-05 0.0026 19.1 1.5 3 23 853 873 852 873 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00029	0.042	15.3	1.7	1	20	683	702	683	705	0.93
2	7	0.00013	0.018	16.4	0.2	2	23	712	734	711	734	0.96
3	7	0.00034	0.049	15.1	3.3	1	23	740	762	740	762	0.99
4	7	0.00015	0.022	16.2	0.8	1	23	768	790	768	790	0.96
5	7	7.4e-05	0.011	17.1	4.3	1	23	796	818	796	818	0.98
6	7	3e-06	0.00043	21.5	2.6	1	23	824	846	824	846	0.97
7	7	1.8e-05	0.0026	19.1	1.5	3	23	853	873	852	873	0.98

Sequence Information

Coding Sequence: ATGGGTCGAAAAATTGAACAATTGACAACAGCTGAGTTAAAAGCGGAATTGGGTAAAAGAAACCTCCAGACTTCGGGGCTCAAAAGGGAATTGTTGCTCCGACTCCAGGACGCTATTACCGAGGAAGGTGGACATCCAGACACGATGCTGTTCGAAGTTCAAGAAGAACAGCAACAAAGCACAGTAAGTACTGCCGATGAAATGCCCGCTTTCATGAAGTTGCTTCTGGGCAAATTCGAGACGCTGGAGAGCGGCCAAAAAGAACAAAAGAATGCTTTCGAAGAACAAAAGAACGCTCTCGAAGACAAATTCGAGAAGCTGGAGAGCGGCCAAAAAGAACAAAAGAACACTCTCGATGAAAAGCTAGATACTAAGTTCGATGAGCAGAAGAAAGCTCTAGAAAGCAAACTTGATTCCCAGAATGCGTTTTTTGAGGAAAAGTTCCAAGCAGTAGATCAAAGAATTGAAAGCGTGGAGGAAAAATTTACTGAAGTCAAATCGGAAGTTGAACAACTGGCTAAGGAGCTGGAGCTAGTTAAGAAACAGAAAGTGCGAGAATATTTGCCCGACGcactagcattcgccctGACAATGGAAGCTGCAGACCAAGCTTCGCAAGGTTGCCATCGCGTAAGGGAAATGGCTGGTCTAGAGTGCTCATGTCAACGCATCGACATCGAAAGGCAAAACACGAACACCACTCGGGGACAAATGAGATGCTGGAACTGTAACAAACTGGGACACCTGCAGCGACAGTGCCGAGCCTTAGTTAGACAAGCGGGTTGCCCACATTGCGCTAAAAGGAGACAGAATGAAGAAGCATCTGGCAGGATGTCGGAGCAGAAGTTGGTTGATGGAATCGACGCCCCCAGGACCATCATCCAAGTCTCGCAAACAAAACGCTGCAACAAGAGTCTGACAATAGAGGCAATCATTGCCAACAGAAGATGCGTGGCCACTATTGACACAGGTGCCACGGCCTCCATCATCCGAAGAGACCTTGTTCAGACGTCATGGCTACATAACACCAGCTGCTACAGTCTGAAGACAGCTACAGGAGAAGCGGCGAAAGTATACGGGGAGGTGCAGCTACAGATACAACTAGAGGGATTGACCTTCTCACATGCATTCTTGGTAGCCGACATATGCATCATTGGAGTGGACTTCATGAAGGCACACGAGGTAATTCTTGACCTTCGAATGCAGGTGCTAAGGTATCGAACCATCGAGATCCCTATGGTATACGGAAACGACAACGCTGTGAATCTTCGAGCAATACTGGGAGGCGATGAAGTTCTACGGCCCTCTTCAGAGACAGTTCTTTGGACACGTTTGGAGGGTGATCCTGGGAACCACCGATTCTATCTCATCGAGCCAGACAACAAAAGTGAATTTAAAAGTTACGTCGTGGGAAAAATTCTTGCAGAGCCCAGGGATAACATGGTGCCGGTAAGACTGATGAACCCAAATAAGCGCACCGTTAAGCTCAGAAAAGGAGAGGTGATCGGAAGATGTGTGCCCGTTGCAGCCATTTCGACAATAGCTGAGAGTGAGCCTGCAAGTCCTGTCTCTCCATCTAAATTGGCCGAGGTATACTGCCGATGTCTATTTGTGTGTGCTGCATGTGATCATGACTTTGAGTTCTTTGACGTTTTCATTGAACACATTGGAGTGGATCATGATTTCCAGAATACATTTGAAAGCAGCGACACAAAAAGACTGGTGTGCATTTCAAACGTGGTAGAGGATAATAATTGCAAGGGGGAAGAATCGACCTTGATTGAGGAAGATACGAAAGACCTCATAGAATTTAAATTGGAAGAAATTATTGAAGAGGGAGCGCCTAGTGAGGAGGCTTATGTCGTTGAACATAACTCTTTAAACCTGGACAATTCCCCAGAGTCTTCGTTAAGCATAGGTGTTGGGTCGTTCCTATCAGATTGTGATGATGTGCCCAAGGAAACTGTTTTGCAAATTAATCCTGATAACTCTAATGAAAATGCAAAAATACGCACAAATCCGTTGCACATAAGTATATTGAAGGAGCACAAGTGTGACATGTGCGGAAAGAAGTATGCAAGCGAAAAAAATCTGGTCCGCCACAAGTGGAGACACTCTAGTCAAACGAAATGGTCTTGTCCTACATGCGGCAAAGTAACAACCACCAAGGATGGCATGATTTTGCACGTCCGCAGAAAGCACACCGGCGAAAAGCCTTTCCAGTGCAAGTTTTGTGAGAAATCATTCGCCTCATCCGCCCAAAGGAATCTTCATCATCGAGTTCACACTGGCTACAAGCCATATGTTTGCGAAAAATGTGGAAAGACATTTAAACTCTATACGGTTCTGCGCTACCACATGGATTGGCATATGGGCGTAAAGAACTACAAATGCGAAAAGTGTGACAAGAAATTCCACTCGACAAGTGAGCTGAATAATCACAAAAGCGTACACACTTGGGAACGGCCATTCCCGTGTCCGGATTGTAACCTGCGCTTTAAGACGCAACGCCATTTGCGGCGACACAAAGAGGTTCACAGCGGTAATCTGAAAATTTGCAAATACTGCAACAAAGGATTTGCACACATTTCCACGCTCACATCGCACTTGAGGGTCCATCAGTTGGATGAGATAGACTAA
Protein Sequence: MGRKIEQLTTAELKAELGKRNLQTSGLKRELLLRLQDAITEEGGHPDTMLFEVQEEQQQSTVSTADEMPAFMKLLLGKFETLESGQKEQKNAFEEQKNALEDKFEKLESGQKEQKNTLDEKLDTKFDEQKKALESKLDSQNAFFEEKFQAVDQRIESVEEKFTEVKSEVEQLAKELELVKKQKVREYLPDALAFALTMEAADQASQGCHRVREMAGLECSCQRIDIERQNTNTTRGQMRCWNCNKLGHLQRQCRALVRQAGCPHCAKRRQNEEASGRMSEQKLVDGIDAPRTIIQVSQTKRCNKSLTIEAIIANRRCVATIDTGATASIIRRDLVQTSWLHNTSCYSLKTATGEAAKVYGEVQLQIQLEGLTFSHAFLVADICIIGVDFMKAHEVILDLRMQVLRYRTIEIPMVYGNDNAVNLRAILGGDEVLRPSSETVLWTRLEGDPGNHRFYLIEPDNKSEFKSYVVGKILAEPRDNMVPVRLMNPNKRTVKLRKGEVIGRCVPVAAISTIAESEPASPVSPSKLAEVYCRCLFVCAACDHDFEFFDVFIEHIGVDHDFQNTFESSDTKRLVCISNVVEDNNCKGEESTLIEEDTKDLIEFKLEEIIEEGAPSEEAYVVEHNSLNLDNSPESSLSIGVGSFLSDCDDVPKETVLQINPDNSNENAKIRTNPLHISILKEHKCDMCGKKYASEKNLVRHKWRHSSQTKWSCPTCGKVTTTKDGMILHVRRKHTGEKPFQCKFCEKSFASSAQRNLHHRVHTGYKPYVCEKCGKTFKLYTVLRYHMDWHMGVKNYKCEKCDKKFHSTSELNNHKSVHTWERPFPCPDCNLRFKTQRHLRRHKEVHSGNLKICKYCNKGFAHISTLTSHLRVHQLDEID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -