Basic Information

Insect: Neoascia interrupta
Gene Symbol: ZNF541
Assembly: GCA_947623515.1
Location: OX392464.1:2029761-2045348[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 6.4e-05 0.0094 17.3 0.2 2 23 195 216 194 216 0.97

2 6 1.7e-06 0.00024 22.3 1.5 1 23 222 244 222 244 0.99

3 6 9.8e-05 0.014 16.8 2.6 1 23 250 274 250 275 0.95

4 6 0.00048 0.07 14.6 0.8 2 23 520 541 519 541 0.97

5 6 0.0039 0.57 11.7 0.7 1 23 1529 1553 1529 1553 0.95

6 6 0.00016 0.023 16.1 0.8 1 23 1587 1609 1587 1609 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	6.4e-05	0.0094	17.3	0.2	2	23	195	216	194	216	0.97
2	6	1.7e-06	0.00024	22.3	1.5	1	23	222	244	222	244	0.99
3	6	9.8e-05	0.014	16.8	2.6	1	23	250	274	250	275	0.95
4	6	0.00048	0.07	14.6	0.8	2	23	520	541	519	541	0.97
5	6	0.0039	0.57	11.7	0.7	1	23	1529	1553	1529	1553	0.95
6	6	0.00016	0.023	16.1	0.8	1	23	1587	1609	1587	1609	0.98

Sequence Information

Coding Sequence: ATGGGTGCCGAAGGATCGGTCACATTGCAACTACGAGAAGCCGTTCATTCGTCGGACTCCTCCTCAGTCGATGGCTGTTCATCGCTGGACAATGCCCTCACGATTGGCTACCCGGATCCGGATATGCTAGCCGATGTTCTAGGTACTCTGCAAACTGCGTCCCTTAACAATAACGCAAACAATAACAACACCATGATTAGCGCCATCACTCTGGAGAGTGTGGATGGTGGTGGAAaactcaatgacatcggctccacaatcagcagcacccccaacaatagtggcggcaccagccagggccggagcagcaacagtaagacgaacaacaacaatggcagccttataagctgtaccagcaacaatatgtcgctgagcagccccattagcggacaaataatcagcatcaccggtagcagcagcggaagcagcggaagtagtagtaattgtagtacaaccagtaatagcagttgtagcagtagcagtaatgagagtatatcaaacgtATCAGTTCCTGGATCTAATCCACCGATTGTGAAGAAACAAAGACCGAAAACATCATCGCCTACACGACATGGACCCCAGCAGTGTCAGGTTTGCAGCAAAGTATTTGGAAATGCATCTGCGTTGGCAAAGCACAAATTAACGCATAGCGATGAGAGGAAGTACGTCTGTGTGATGTGTTCAAAAGCGTTCAAAAGACAGGACCATTTAAATGGCCACATGATGACTCATAGAAATAAGAAACCATACGAATGCAAGGCTGAAGGTTGCGGCAAGTCGTACTGTGATGCAAGATCGTTGAGGCGGCACACAGAGAACCATCACAGTGGACTGGCGGCGGCTGCCACCACCCCCCAGAACCAGTCGTCCTCGCTTTCGCCATCGACAGGGCCGCCCACAGGACTCAGTCTATCGCCGGCAACTGCCAGTGGAGACGCAAGTTCACCCCATGGAGCGAACGGAATTCAGTATACAACTACGGGAAGCGGTGACGATGGCAGTGGCTGTAACAGCACAAGCTCTGGGAAACAATCGTCATCAGCTGTTAATGTGTCAGTTGTGTCGTCGTCTACGCAAGCAAGCTCTGCTTCACAGTGCTACTCATCGACACCGTCACCTGCATCGTCGCCTTCGTCGAACACCTCTGTTAAGTCGGTCGCCGCTAATGAGGGACTCACCAGGCAGCAGCTGGATCTCATTAGTCAAATAATGCAACAAACGAAGCAGGGCAGTACCCAAGTGACTGTGGCCACCACTACGGCGGGCTTGAAGATTGCAAATCAACCACCGTCTCCACATCAGAGTCAGACTCAGAGCCAGTCACAGCAACAATTGCAGAGACCAAGGACATGGAATATGCAGACTCAGCTACAGCAGACACAGTCGAAAATCTCATCAGTGTCGGTGATTGAAAACGCCACCTCGCCGATCACCTCAATCTCAATTAACGAGCTACTAAACGGGAGTGGGCCCCATCAGCAGCAACAGCAGCAAATAACGAGCGCCGGAATAAACCAACAAATTTTAAACATTGTAAAAATAGAGCAGAAACCTGTCGAGTGCAACCTATGTCATAGAAAGTTCAAGAACGTGCCCGCTCTAAACGGGCACATGCGCCTGCACGGTGGCTACTTTAAGAAAGAAGCCGAGACAAAGAAATGCGATCGCAAAGATGGCCTCGGTCCGCCACTGCAGACGGCGAGCATTGGTGTTCGGGCTCTTATCGAAGAGAAGATCATAAGCAAGCGATGTAAGGATCTGAAGGTAATAGGCCCGAACCGATGCCTCTTGCAGTCGTCTGAACGGAATCATTCTCTATTGCAGGGTGCCTTCGTAGTTCCTGCCCCACCCATAGCGGCTGCGGTTAGACGCGCAGCCAGCGACATAGAAAACTTTTTGGCACCCAAATCACCGATAGTTCTCCCGACCGGCGGCTCGCCGACATCTTCGGAACGGAACGGCAGCAACAGTCTAAGCGAGACCGGTACCACCGTACTTCTATCGGGTCTGCAAATCCAAAAACAATCAACTCCAATCATCCACCAGAAACCGAATAACATAAGTGTTGGCACGACAACGGTCTCAACAAACACTTCCAAGGGCACCTCCACCATGGATCACAAGGACGCTACTCTGATTGAGCTTTTAAAGCGAGGCACTAAAGTGGCGGTAAGGAAAACAGGCTCCGGCTCAGACTCGAGCCAAATTTTCACCACCAGCAATGGAACGTTGATGCTGCCCTCAGAGCTGTCGCTGTCCTCGTCTGGATCGTCGAACCCACCACTAGCGATAACCCTGCCAAATGGCGAAACCACTCCCGTATCGCTAACGATATCCCAGGCCTCGAATGGTTCCGGTGATGTGTATACGCTGACCTACTCCACCGATTCGGCTGCTTCGTTTTTCGAGGACAGTGATGTCTACAGTGTATCGGAGACAGATATGCTGTTGCAGACAGTCGACTCTATACAGCTGCTCAACGACGCCGAAGCGACAGATGAGATTAGCTCCCTGACCGATTATCCCACTGAAAGCAGCACAACATCCAGCCTGAGAGAAATCGCAAGCGGATCCACCAAAGACTTGCAAGCGGTATTCAGTTCCCCCTTGCAAGAGGCATTGCCCGACTTCCAAACAATTCATTCCAAGGATTTTGTCCTGTACAACAATGGCACATGCAAAGCACTAAACGGTGGCACTCAGACCACAAATAAATCACTGACTACGCTGGCCAAGCAGTCACTATCGCCCCTTCCCTCGCCGCTTGCGTATCCCACGCCTCCAGCCAGCCATGAGACAGTAACACAATCGTCGCCATTCCTGGATGACTCCCATCACTTTTCGGATGCAGCAAACTCCTTCTTCCAGGAGAAATCCACAACCGATTTCATTGATGATGCCGGGGGGACTTTCTTCAAGGACTGCTCCAATGAGGCACTTACAGAGAGCCAGAAGATCCTCAAATTAAAGAGCGTCCTCGAGGATAGCGGTCAGTTCTTTAAGTCAAACGAAGAGAACTCAAGCGATGTCTTTGACACCTCAGTGGTCAAGGTGGAGGACCTGCTGAACGAGTCCAACGACGGCGCCAACTGTGATCTCAAGGATTTTGCCGAACAGAATCTCTCGTTCTTGGACGATGCTCAAGGATTTCTCGATGACTCGCGCAATGCCACCTCACCACTGTCGGAGTCATTCTTCACCAGCGGTATTGGTACAGCAGAGGAGGTGAAAGAAGTATTGCGCGATGTTCTGCCCGATGAGTCACTCAACTGTGATCCACAAAACTCAACCGACATTGATCTGTATTATCTGCCTGGCTTGGGCCTACAATCCCAAATGATGCCCAACTCCGACGATCCCTTGTTATCGTCCTCACCGAGGGATTTCGGCCACAGGCAACACTCACAACCCCACCACCAGCAATCGCAGCTAGTTCGCATGGAGCAGTCCACAGCGGCAGCGCTACAAGTGCAATTGCATCCAAAGAAACCAGAACCTGATCCAAGCTTCCCCATGCTTTTGGCCACGAGCACGTCCAGAGATGGAAGCACCCAATTCCATTTCAGTATGCAACAGCAGGAGGTTAAGCAAAACAACGAAATCGAAACTAAACACGATGTGCCCTCGAGTCAAACGGGCGCCATAGTTTCTGAGCAACAAACCCCAGCTCAACCACATTCGTTTAAAGACACCCAGCTTAAAGTGACGCAATACTTTGCAACGAGTGATTGCATAGGCCAGCAGCCCCAGAATGTCTTGTCTACGGCAGCAACCGCGTCTCCCCTCACCAGTTCAATTCTGAAGAGGAGATTGCGGCAAGGATCGATCGGTGGTGACAGTGGCTCACATGGCAGTATTCCCCGAAAGTATGAGCTGTACAAGTCGAAGCTACGGAAGCCATCAACGACACACTATACTCCTCAGCCAATCCTAAATCCAGACCGAAAGGGGACAGGTTTGTATTCCAACCTGCCCAAACCACCCACCTTCCACCAAGATGCTTTGCACTTGGATGACGAATTCGAAGAAGCCGCCAGCTTGATGGCTTTCCTCGACGAGTCCAAGGTGAACATCGGTACCGCATATCAAGCAACAATTCCACCCATCGAGAGAGCGTGCTCGTCGATGCAGCAATGCATTGCCGAAGCCACCGATCATGAAGAACTTATGTGGGACCCCTGCGTGGCTATCGACGAGAAGATTCTAACGCGTTACATCGAGCTAAGCAAATCATCAGCCATTCCACTTGGTTACCATTCGGAGGAGGTTGCCCTCAAGGCACTTCTAGAGGTGAATGGCGACACTCCAATTGCAGTTCTCAACCTTCTTAAGTCGCAATCGAATCCCTTCCACCTCAAGTGGTCGTCGCTGGAAGTTGAAATATTCCTGAGGGGCTTGGAGAAGTATGGCAAAGATTTCTACAGTATCGCCAAGGAGATTATAACAAAGTCGACAAGTGAGTGTATCCAGTTGTACTACTTCTGGAAGAAGCTCTGTGTGGACTACAAGGCGACACACTTGAAGATCGAAAATGACGAGGCCAGTCAGTCACACTTTTCCTCACAGACTTCTGAGCTTCGTCCGCATGTCTGCGAAATGCCCGATTGTTCAGCAAGCTTCACATCAAAAGCAGCCCTCCATGGTCATACCCGGATCCATTGCATTGGCCGCAACATGCATCAGCTGAACAACAACAATAGCTCCTTGATGTTTGGCACCAATGGCCAATTGCAAGCAAACCCAAATTTGAAAGACGACTTTCCCTGCAAGGTGTGCGGCAAAGTTTTCAATAAAGTCAAAAGCAGAAGTGCTCATATGAAATCGCATCGTCCTCAGGAAAATGATCCGACTAATCAGCTGCAACAGCAACAGCAACAACAACAACAACCACCACCACTACAACAACAGCAACAGCCACAGCAAAATACAATTTCATCATAA
Protein Sequence: MGAEGSVTLQLREAVHSSDSSSVDGCSSLDNALTIGYPDPDMLADVLGTLQTASLNNNANNNNTMISAITLESVDGGGKLNDIGSTISSTPNNSGGTSQGRSSNSKTNNNNGSLISCTSNNMSLSSPISGQIISITGSSSGSSGSSSNCSTTSNSSCSSSSNESISNVSVPGSNPPIVKKQRPKTSSPTRHGPQQCQVCSKVFGNASALAKHKLTHSDERKYVCVMCSKAFKRQDHLNGHMMTHRNKKPYECKAEGCGKSYCDARSLRRHTENHHSGLAAAATTPQNQSSSLSPSTGPPTGLSLSPATASGDASSPHGANGIQYTTTGSGDDGSGCNSTSSGKQSSSAVNVSVVSSSTQASSASQCYSSTPSPASSPSSNTSVKSVAANEGLTRQQLDLISQIMQQTKQGSTQVTVATTTAGLKIANQPPSPHQSQTQSQSQQQLQRPRTWNMQTQLQQTQSKISSVSVIENATSPITSISINELLNGSGPHQQQQQQITSAGINQQILNIVKIEQKPVECNLCHRKFKNVPALNGHMRLHGGYFKKEAETKKCDRKDGLGPPLQTASIGVRALIEEKIISKRCKDLKVIGPNRCLLQSSERNHSLLQGAFVVPAPPIAAAVRRAASDIENFLAPKSPIVLPTGGSPTSSERNGSNSLSETGTTVLLSGLQIQKQSTPIIHQKPNNISVGTTTVSTNTSKGTSTMDHKDATLIELLKRGTKVAVRKTGSGSDSSQIFTTSNGTLMLPSELSLSSSGSSNPPLAITLPNGETTPVSLTISQASNGSGDVYTLTYSTDSAASFFEDSDVYSVSETDMLLQTVDSIQLLNDAEATDEISSLTDYPTESSTTSSLREIASGSTKDLQAVFSSPLQEALPDFQTIHSKDFVLYNNGTCKALNGGTQTTNKSLTTLAKQSLSPLPSPLAYPTPPASHETVTQSSPFLDDSHHFSDAANSFFQEKSTTDFIDDAGGTFFKDCSNEALTESQKILKLKSVLEDSGQFFKSNEENSSDVFDTSVVKVEDLLNESNDGANCDLKDFAEQNLSFLDDAQGFLDDSRNATSPLSESFFTSGIGTAEEVKEVLRDVLPDESLNCDPQNSTDIDLYYLPGLGLQSQMMPNSDDPLLSSSPRDFGHRQHSQPHHQQSQLVRMEQSTAAALQVQLHPKKPEPDPSFPMLLATSTSRDGSTQFHFSMQQQEVKQNNEIETKHDVPSSQTGAIVSEQQTPAQPHSFKDTQLKVTQYFATSDCIGQQPQNVLSTAATASPLTSSILKRRLRQGSIGGDSGSHGSIPRKYELYKSKLRKPSTTHYTPQPILNPDRKGTGLYSNLPKPPTFHQDALHLDDEFEEAASLMAFLDESKVNIGTAYQATIPPIERACSSMQQCIAEATDHEELMWDPCVAIDEKILTRYIELSKSSAIPLGYHSEEVALKALLEVNGDTPIAVLNLLKSQSNPFHLKWSSLEVEIFLRGLEKYGKDFYSIAKEIITKSTSECIQLYYFWKKLCVDYKATHLKIENDEASQSHFSSQTSELRPHVCEMPDCSASFTSKAALHGHTRIHCIGRNMHQLNNNNSSLMFGTNGQLQANPNLKDDFPCKVCGKVFNKVKSRSAHMKSHRPQENDPTNQLQQQQQQQQQPPPLQQQQQPQQNTISS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01522200;
90% Identity: iTF_01044660;
80% Identity: iTF_01044660;