Nint001280.1
Basic Information
- Insect
- Neoascia interrupta
- Gene Symbol
- topi
- Assembly
- GCA_947623515.1
- Location
- OX392464.1:27060736-27063015[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 1.7 2.4e+02 3.4 1.6 2 21 131 149 130 150 0.93 2 11 3.8e-05 0.0056 18.0 2.9 1 23 217 239 217 239 0.97 3 11 2.2 3.2e+02 3.1 0.1 2 19 343 360 342 362 0.92 4 11 1.6 2.3e+02 3.5 0.0 1 20 370 389 370 391 0.91 5 11 0.038 5.5 8.6 0.9 1 21 410 430 410 434 0.90 6 11 0.011 1.7 10.3 0.0 2 23 449 471 448 471 0.89 7 11 4.5e-07 6.6e-05 24.1 2.0 1 23 486 508 486 508 0.95 8 11 0.002 0.29 12.6 1.0 1 23 514 539 514 539 0.95 9 11 0.42 61 5.3 1.6 1 23 545 567 545 567 0.88 10 11 5.9e-07 8.7e-05 23.7 0.2 3 23 575 595 573 595 0.98 11 11 0.0087 1.3 10.6 1.4 3 23 603 624 601 624 0.95
Sequence Information
- Coding Sequence
- ATGAATTGTGCAAACTTATGTACCGGAGACGAAGAGTACTCCAATTCAGAAGCATGGTTAGCTGAGCAAATATTTTCTCAGCTTAAAGACTTCAATACGGAACCTCCGAAAGCGAAGGATGAGGAAATCGTTCAGGCCAACGCTGAAGAACAAAATAGCTCTCAAGAAACCGAACCCACAATTAGCCCTGACGTGATTGACTTGAGTACTCCGCAGGCCAATGAGCTGAAGCATAAAGAAAGTCAACAACAGCATGTTATCGCTAGTCCCAAGATAAGATTTGAGTTTCCAGAGCAGCATGTGGCTGGAGTAACAAATGAAGAACATGCTCCGCGGGACTGTTTGGAACCGCCGCCGACATTCGCTGCCCAAAACCGTTTTCAAATCATCGAGTGTGCCAACTGCAACTGCATCTTTGACCTTGATTCCTTTCGTCAACACATTTGTGACTACAGCGAGGACAACAGCCTAATTGTTCCCGAGCCGACGGAGCAGCATTCGATGCTCGCCTATGAGGCTGGACCTCCTGAACCGCCATGCATGCGTTTGTTGCGTGAAAATCAAATCCGTATCCGGCGCTTTCTCAAAGACGAACTCAAATACGATTTGAATGCCGGGAGTGCAACAACCAGAAAGCAAGACGGTCCACACGAGTGCACGCTGTGTGAAAGAAAGTTTGTTCATGCTTCTGGGCTTTCGCGTCACATGGAGAAGCACGCTCTTGACCTGATACCAAGCACATCGTCCACAAATCCAAATAACGGCTATCAGACGGGCAACGGTTTGAAGGTGGTAATCAAGTGTACCATTTGCGGTCTCATACACTACGAACCGGAGCCAGCATGTAAGCACTTTTTGTCTCATTTTTCCGGTTCCCATGAAAAAAGCCCCGATGGACAGGATGTTGGGGCGTTTCCCTACGAGAACTACCTGGACGATGCTCTGCAATTCTTAGAAACTGAGTCCAATAAAACCGAAACAAAGCCCCATGCCTACCTCAAGCTGGTGATACTCAGTTGTGTGCTCCAATGTGAGTTTTGTAATTTACTTTTCTCAGAGGTGTCGTTTTTACTGGCACACTCGGCGTGCCACCAGCCCCTGCGGCGGTTCGAATGCTTTAACTGCGAAATCAGTGTTCCTACGTCCAAAGAGGTGTTCTTGCACTGGCAGGCCGAATGCGTCTTTTCCAGGGAGAACCTTAAGCGTGGATGCTCCTCGCAGCGGTACTACGTGTGCAACGTTTGCGAAAACAAGTTCGGTTCACTGGAACAGCTGCATGAGCACAGGTATTCCGCCTATCATTTCTTTCCAAGGCTTGAAAAGAGCCAAGGAATTCTGCTTCTGCCTTGCGAGTACTGCGATGCGGTGTTTGAGACAGCCAGCGAAATCGTGAGCCACTACGATGAGAGGCACTACAAGAAAAACAAACGTGATCCCGGTGCAAAGTACCGCCAGTACCTGTGCGAAATTTGTGGGAAGACCTACACCCAGTCCAGTCATCTGTGGCAACATTTGAGATTCCACAAAGGTGTCAAGCCTTTTGCATGCAAGGAGCCAGGCTGCACCCGTCGTTTCACTATTCGTCCCGACCTCAACGACCACATCCGAAAGTGCCACACTGGCGAGCGACCCTACCACTGCCTGATCTGCGGCAGACGTTTTCTGACGGGATCGGTGTTCTACCAACACCGGCTTATTCATCGCAACGAACGTCGTtacggctgcgatgagtgcgggaagagattctaccgagctgacgccctgaaaaatcaccttcgtatccataccggagagaagccgttcggatgtttgttctgcacaaaaagctttcgccagCGTGGAGATCGCGACAAGCACATTCGAGCAAGGCACTCTAGCCTAGACGCAAATGCTCGCCTCATGATGCAAATGCATAAGCTGCAGCTGGAGGCAGCCGCCAGGGCCAATGCAACGGGCTCAACGACCGCCGTCGAGGATGTTCTCATGCTGGGAAACATACCATTCCCGAAGAGCCTGTTTCAGCCCATCTTGACTGACATAGATTCTTCTGCCCAACAATGA
- Protein Sequence
- MNCANLCTGDEEYSNSEAWLAEQIFSQLKDFNTEPPKAKDEEIVQANAEEQNSSQETEPTISPDVIDLSTPQANELKHKESQQQHVIASPKIRFEFPEQHVAGVTNEEHAPRDCLEPPPTFAAQNRFQIIECANCNCIFDLDSFRQHICDYSEDNSLIVPEPTEQHSMLAYEAGPPEPPCMRLLRENQIRIRRFLKDELKYDLNAGSATTRKQDGPHECTLCERKFVHASGLSRHMEKHALDLIPSTSSTNPNNGYQTGNGLKVVIKCTICGLIHYEPEPACKHFLSHFSGSHEKSPDGQDVGAFPYENYLDDALQFLETESNKTETKPHAYLKLVILSCVLQCEFCNLLFSEVSFLLAHSACHQPLRRFECFNCEISVPTSKEVFLHWQAECVFSRENLKRGCSSQRYYVCNVCENKFGSLEQLHEHRYSAYHFFPRLEKSQGILLLPCEYCDAVFETASEIVSHYDERHYKKNKRDPGAKYRQYLCEICGKTYTQSSHLWQHLRFHKGVKPFACKEPGCTRRFTIRPDLNDHIRKCHTGERPYHCLICGRRFLTGSVFYQHRLIHRNERRYGCDECGKRFYRADALKNHLRIHTGEKPFGCLFCTKSFRQRGDRDKHIRARHSSLDANARLMMQMHKLQLEAAARANATGSTTAVEDVLMLGNIPFPKSLFQPILTDIDSSAQQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -