Basic Information

Insect: Nemotelus pantherinus
Gene Symbol: ZFX
Assembly: GCA_963978885.1
Location: OZ022263.1:10645807-10651457[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00029 0.077 15.6 3.4 1 23 88 110 88 110 0.98

2 10 0.00011 0.03 16.9 0.2 1 23 116 139 116 139 0.94

3 10 2.1e-05 0.0056 19.2 0.8 1 23 145 167 145 167 0.97

4 10 1.4e-05 0.0037 19.8 2.5 1 23 173 195 173 196 0.96

5 10 0.00034 0.09 15.4 0.1 1 23 201 223 201 223 0.98

6 10 0.14 36 7.2 6.3 1 23 242 262 242 262 0.97

7 10 4.5e-07 0.00012 24.5 3.2 1 23 268 290 268 290 0.96

8 10 0.00013 0.035 16.7 1.4 1 23 296 318 296 318 0.99

9 10 0.0082 2.2 11.0 0.5 1 23 324 350 324 350 0.90

10 10 0.00031 0.083 15.5 0.3 1 20 356 375 356 377 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00029	0.077	15.6	3.4	1	23	88	110	88	110	0.98
2	10	0.00011	0.03	16.9	0.2	1	23	116	139	116	139	0.94
3	10	2.1e-05	0.0056	19.2	0.8	1	23	145	167	145	167	0.97
4	10	1.4e-05	0.0037	19.8	2.5	1	23	173	195	173	196	0.96
5	10	0.00034	0.09	15.4	0.1	1	23	201	223	201	223	0.98
6	10	0.14	36	7.2	6.3	1	23	242	262	242	262	0.97
7	10	4.5e-07	0.00012	24.5	3.2	1	23	268	290	268	290	0.96
8	10	0.00013	0.035	16.7	1.4	1	23	296	318	296	318	0.99
9	10	0.0082	2.2	11.0	0.5	1	23	324	350	324	350	0.90
10	10	0.00031	0.083	15.5	0.3	1	20	356	375	356	377	0.94

Sequence Information

Coding Sequence: ATGCATCGAAAATCACGCAAATCGGATAGTGCATCATCGACCACGGCAAATTCAGCAGCCAACGACAGTGGAATACTGTTGTCGGATGTTACATCGGAAAATACCAGTATAAAATCCCTTGATATCGGGTCAACGAGAAGACAGCGAGCAAGAATTTCGCCTGCTTCTAAACGCTCATCGTCGACCTTATCTGAATGTCGAAGCTCTAATGGCAGCAAACCGAAACAACGGACACGTCGAACGAAAAAACCTCGAAAGGAGTACGTTTGCCATGTCTGCGATAAACATTTTCTCGGATCGAGTGATCTCCGCAAACATTCGCGAATCCATACAGACGAACGACCGTTTGCTTGCGAAAAGTGTCCTATGAAATTCAGGCAATCAATTAGTTTGAAAAATCACGTCGCTTCGATACATGGAACAGATCAGAAATTTGCTTGTGACCAATGCAAGAAATCGTTTCCGTTAAAGGAAAGACTCAAATTGCATATGCGGGTACATTCAGGTGAAAAACCTTATCGCTGCTCGCAGTGTCCGAAAACTTTTGCTCGGGGTGGAACGCTTCGCCAACATATGTTCTCGCATCACggtacaaaaaaattcaaatgtctCGAGTGCCCCGCCTCATTTCCGTCACTCAACGGTCTTCGCCTGCACACGAAAATCCATTCGAACGTACTTGAAAAAAAGCAAATCGTTATACCAGCAGCAAAAGGAAAAGAATTCCATTgtaaaatttgcaataaaacgtTAAAAGGTCATCTTCTACAGCACATGAAAAGTCACGAAAATATTCGTTCGCATGCATGTAATATTTGTGGCTTGCAATTTTCACAGAAATCACACTTGAACGTTCACCAACGAATGCATTCGGGCGAAAGACCATATCGGTGTCGGGTCTGCTGGCAAGCCTTTGGTCATTCTAGTGTGCTCAAGCTGCACATTCGAAAACATACCGGCGAGAAACCTTTCAAATGTCTCGTTTGTACCGAAAAGGGTGTTGCTTTTTCCCAACTGCCACATTTGAAAAACCACATGAAAGTCATACACAACAAAGACAAACCATACATGTGTGAAGCTTGCCAAGAATTCTTCAAAACCAAAAGCGATCTCAAAATCCATTTGGATTCAGAGTGCACTAAATCCAATCCAGACGAGTCATCGCAGAGTTCGCAAAACGACGAAGAGACCAATCTATCGAAATTACGTCTACTCGTGGCCATTCTGATCAAACAGATCTCTACCGAAGACCGTCTGAAACAACTAGGATTCGAAAAGCGTCTCATCGACAACGTAATTATTAGTGCATTAAAATTAGCAAAACGTCGGTGCTACGATGATGAGACGCTGAACGAAATGGATCGTTTTCGGCTTAACATAACCGAATTTCTCGAATGGACAATTCCCGAGAAGTTTATGACCAAGTTTCGAGAAgagaaaaaatcaattgaagaTCTACTGGAAGATCTAACTTCGGCCTATAAGACCCCGAACGATTCTCTTCCAGATCGTAATGGAGACGATGCATGA
Protein Sequence: MHRKSRKSDSASSTTANSAANDSGILLSDVTSENTSIKSLDIGSTRRQRARISPASKRSSSTLSECRSSNGSKPKQRTRRTKKPRKEYVCHVCDKHFLGSSDLRKHSRIHTDERPFACEKCPMKFRQSISLKNHVASIHGTDQKFACDQCKKSFPLKERLKLHMRVHSGEKPYRCSQCPKTFARGGTLRQHMFSHHGTKKFKCLECPASFPSLNGLRLHTKIHSNVLEKKQIVIPAAKGKEFHCKICNKTLKGHLLQHMKSHENIRSHACNICGLQFSQKSHLNVHQRMHSGERPYRCRVCWQAFGHSSVLKLHIRKHTGEKPFKCLVCTEKGVAFSQLPHLKNHMKVIHNKDKPYMCEACQEFFKTKSDLKIHLDSECTKSNPDESSQSSQNDEETNLSKLRLLVAILIKQISTEDRLKQLGFEKRLIDNVIISALKLAKRRCYDDETLNEMDRFRLNITEFLEWTIPEKFMTKFREEKKSIEDLLEDLTSAYKTPNDSLPDRNGDDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -