Basic Information

Insect: Nemotelus pantherinus
Gene Symbol: zfh1
Assembly: GCA_963978885.1
Location: OZ022266.1:65779349-65781609[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.44 1.2e+02 5.6 6.4 1 23 129 152 129 152 0.97

2 16 1.8e-05 0.0048 19.4 6.0 1 23 180 202 180 202 0.99

3 16 0.0002 0.052 16.1 0.3 1 23 220 243 220 243 0.96

4 16 0.05 13 8.6 0.9 2 23 252 273 251 273 0.96

5 16 0.0026 0.7 12.6 0.0 3 23 278 299 277 299 0.94

6 16 5.3e-06 0.0014 21.1 0.2 1 23 333 355 333 355 0.99

7 16 5.5e-05 0.015 17.9 1.9 2 23 365 386 364 386 0.97

8 16 4.7e-05 0.013 18.1 0.4 1 23 392 415 392 415 0.97

9 16 0.00019 0.049 16.2 1.8 1 23 420 442 420 442 0.98

10 16 1 2.8e+02 4.4 0.7 1 11 446 456 446 468 0.86

11 16 6.3e-05 0.017 17.7 1.6 1 23 474 497 474 497 0.97

12 16 1e-05 0.0027 20.2 3.5 1 23 503 525 503 525 0.99

13 16 0.00044 0.12 15.0 3.0 1 23 534 556 534 556 0.97

14 16 0.00072 0.19 14.4 3.6 1 23 562 584 562 584 0.92

15 16 0.027 7.2 9.4 1.6 1 23 590 612 590 612 0.94

16 16 0.014 3.8 10.3 0.6 2 22 619 639 618 639 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.44	1.2e+02	5.6	6.4	1	23	129	152	129	152	0.97
2	16	1.8e-05	0.0048	19.4	6.0	1	23	180	202	180	202	0.99
3	16	0.0002	0.052	16.1	0.3	1	23	220	243	220	243	0.96
4	16	0.05	13	8.6	0.9	2	23	252	273	251	273	0.96
5	16	0.0026	0.7	12.6	0.0	3	23	278	299	277	299	0.94
6	16	5.3e-06	0.0014	21.1	0.2	1	23	333	355	333	355	0.99
7	16	5.5e-05	0.015	17.9	1.9	2	23	365	386	364	386	0.97
8	16	4.7e-05	0.013	18.1	0.4	1	23	392	415	392	415	0.97
9	16	0.00019	0.049	16.2	1.8	1	23	420	442	420	442	0.98
10	16	1	2.8e+02	4.4	0.7	1	11	446	456	446	468	0.86
11	16	6.3e-05	0.017	17.7	1.6	1	23	474	497	474	497	0.97
12	16	1e-05	0.0027	20.2	3.5	1	23	503	525	503	525	0.99
13	16	0.00044	0.12	15.0	3.0	1	23	534	556	534	556	0.97
14	16	0.00072	0.19	14.4	3.6	1	23	562	584	562	584	0.92
15	16	0.027	7.2	9.4	1.6	1	23	590	612	590	612	0.94
16	16	0.014	3.8	10.3	0.6	2	22	619	639	618	639	0.95

Sequence Information

Coding Sequence: ATGAACGATTCGCCTTTGGTAAGCGATACAATTCTCGCTATAAAGGAAGAAATCGATTTTGATGAAACGCAATTGCAAGAGCAATTATACGATGAGTTGGCTGGCAAAAAGTTTCAAAAAGAATACTATCGGAATCGAATTAGTAAAGGTTCTGATCGGATTTGGCCAGATTTATATTGTGCGGTAACTAATCGACATTGCTGTCTTCTTTGTCCGGGCTCATACAAGAACAGAAGGTCGTGCATAGACCACATGAGAGGAATTCATTTATGCACTCCTGACGAAGTAGAAAACGATCAACATATATGCAACGAGGGAAAATGCGGCCGACCAAAACCCGAGGTTGATTCATGGCCAAatttattttgtgaaataacACAACGCCATCAATGCCTACATTGTTCAGTCTCGTACAAGAACAGGCGGTCGTGTATCGCACACATGAAGTCGATTCATCCAAGTGTCATTCCACAGAGATTATTATGTCACACTAAACCACGTCCTGCAAAAGCAGAAACTACAAAAAACAGAAACGCTTTCAAATGCCAATTCTGTCCAAAAGTATTTTTTCATAAGAGCTCACTGTCAACACACCGAAGAACTCATCCGGAACGGAAATTATTCAACGCCGAATCCGGGGATCCAGTGAAACAGCCATTCAAGTGCCCAAAATGCCCCAGAAGATTCGCCGCTTGGGCTGTGTTTCAACGGCACATAGACAAACGGCACCGCGAATTTCGAACAGAGCCCCAACGGTGCTTGATTTGCTTAAAGGTCTTCGGGAACAAAACTGTATTCAAACTTCATGTGAAACAACATATCGAAAAGATTTGTCCGGTATGCAATGAGGTAACCACTGATAGCAACGCACTTCAAGACCACGTCAAAGCTTTGCATATTGGCAAAGTTGAATTTATGTGTCCAATGTGCTACAAGCTTTCTATGAACAGTTTTAGGCATGAAATTCACGTGAGCACTCACACCGGAATACGGCCCTACAGATGCGATCTATGTCCCAAGGACTATACCAGTCCCGTGGGTCTGGAGCGACATATAAAAAAGCATTTGGGAATACCCAGGGGCGGGGAGAAGAAATGCCAGATTTGCTCGAAGGTCTTCAAATCCGCGCAGCATCTAGGTAATCACATGTACGTTCACACTGGCGCACGGCCATTTGAATGCAACGAATGCCTCATGTCGTTCAGATCCCCTACAACGCTCACTACGCATATCGAACGTCTTCACAACAAGCAAGTCTATTCGTGTCGAGTATGCAGCAAAGGTTTCTCGTCACGAGTTAATCGGCAAAGGCATGAACGATCGCACAAACAAATGTTTCCCTGCCGAATTTGCGGCAAAGAATATTCTTGGCGGCGCAGTCGTACTTTCCATGAAAAGAAACACACCAAAGGGTGCTTGTTCGAGTGTTCCAACTGCGACAAGAAATTCTTTGCCAATTATCAACTCGAACGTCACACAAAAATAATGCACGACACTGATGGCCCGTTCCAGTGTAAAATATGCTCTGAGATGTTTAGTAACCGTGACTTCCTACGCGACCATATGCACACGCATGCAAAAGCAAAGGATCGTTTAAAATACAACTGCACACTTTGCGAGAAATCTTGCTATTCAAAGCAGTTGCTAGAAGCCCATATGAATTTTCATCGAGGCGAGCGTCCTTTCGAGTGCGATATCTGCTCGAAATCATTTTACGGTAAAGACTCGTTGACTAAACATTGCAAATTGCATACGGACGAACCGAAATTTGAATGCACGGTTTGCGATAAAAGATTCATGGTCGATAAACATAGACGTGTACATGAGGCAACGCACTCAAATCCGAAACCGATTCAATGCCAAGTCTGCGAAATGTATTTTGTGACGGAATTTCAATTGCATAGCCATTTGCGGAAGCGGAAATGCACCCCAAATGCGTTGAAATCTGGTTTGGTTGATCGAGAAAACGAAAATGCAATATGTGCTCAAGAGCGCGAAGAATGTCAGTCTGATATTGAATTCCAAGAAGACAATGAACAACAAGCTCAGGAAATAAATGAGGTTCCTCCTGAGAAGCAATTGTGTACGTAA
Protein Sequence: MNDSPLVSDTILAIKEEIDFDETQLQEQLYDELAGKKFQKEYYRNRISKGSDRIWPDLYCAVTNRHCCLLCPGSYKNRRSCIDHMRGIHLCTPDEVENDQHICNEGKCGRPKPEVDSWPNLFCEITQRHQCLHCSVSYKNRRSCIAHMKSIHPSVIPQRLLCHTKPRPAKAETTKNRNAFKCQFCPKVFFHKSSLSTHRRTHPERKLFNAESGDPVKQPFKCPKCPRRFAAWAVFQRHIDKRHREFRTEPQRCLICLKVFGNKTVFKLHVKQHIEKICPVCNEVTTDSNALQDHVKALHIGKVEFMCPMCYKLSMNSFRHEIHVSTHTGIRPYRCDLCPKDYTSPVGLERHIKKHLGIPRGGEKKCQICSKVFKSAQHLGNHMYVHTGARPFECNECLMSFRSPTTLTTHIERLHNKQVYSCRVCSKGFSSRVNRQRHERSHKQMFPCRICGKEYSWRRSRTFHEKKHTKGCLFECSNCDKKFFANYQLERHTKIMHDTDGPFQCKICSEMFSNRDFLRDHMHTHAKAKDRLKYNCTLCEKSCYSKQLLEAHMNFHRGERPFECDICSKSFYGKDSLTKHCKLHTDEPKFECTVCDKRFMVDKHRRVHEATHSNPKPIQCQVCEMYFVTEFQLHSHLRKRKCTPNALKSGLVDRENENAICAQEREECQSDIEFQEDNEQQAQEINEVPPEKQLCT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -